Page last updated: 2024-10-06
Urate synthesis
Proteins (2)
| Protein | Synonyms | Taxonomy |
|---|
| Xanthine dehydrogenase/oxidase | | Gallus gallus (chicken) |
| Cytosolic purine 5'-nucleotidase | EC 3.1.3.5; Cytosolic 5'-nucleotidase II | Gallus gallus (chicken) |
Compounds (11)
| Compound | Description |
|---|
| hydronium ion | |
| NADH | |
| Orthophosphate | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Inosine Monophosphate | Inosine 5'-Monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. |
| hypoxanthine | A purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway. |
| inosine | A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed) |
| uric acid | An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| xanthine | A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed) |
| ribose 1-phosphate, (alpha-D)-isomer | |