Uptake and function of diphtheria toxin

Proteins (7)

Protein	Synonyms	Taxonomy
Heat shock protein HSP 90-alpha	EC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38	Homo sapiens (human)
Heat shock protein HSP 90-beta	HSP 90; Heat shock 84 kDa; HSP 84; HSP84	Homo sapiens (human)
Elongation factor 2	EF-2	Homo sapiens (human)
Thioredoxin reductase 1, cytoplasmic	TR; EC 1.8.1.9; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1	Homo sapiens (human)
Proheparin-binding EGF-like growth factor		Homo sapiens (human)
CD9 antigen	5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24	Homo sapiens (human)
Diphtheria toxin	DT; NAD(+)--diphthamide ADP-ribosyltransferase; 2.4.2.36	Corynephage beta

Compound	Description
hydronium ion
niacinamide	An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
nad	A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)