Page last updated: 2024-10-06

Signaling by ERBB2 ECD mutants

Proteins (11)

ProteinSynonymsTaxonomy
Epidermal growth factor receptorEC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
SHC-transforming protein 1SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1Homo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
GRB2-associated-binding protein 1GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1Homo sapiens (human)
Pro-epidermal growth factorEGFHomo sapiens (human)
Hsp90 co-chaperone Cdc37Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37Homo sapiens (human)
ErbinDensin-180-like protein; Erbb2-interacting protein; Protein LAP2Homo sapiens (human)

Compounds (4)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.