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Regulation of thyroid hormone activity

Proteins (3)

ProteinSynonymsTaxonomy
Thyroxine 5-deiodinaseEC 1.21.99.3; 5DIII; DIOIII; Type 3 DI; Type III iodothyronine deiodinaseHomo sapiens (human)
Type I iodothyronine deiodinaseEC 1.21.99.4; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinaseHomo sapiens (human)
Type II iodothyronine deiodinaseEC 1.21.99.4; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinaseHomo sapiens (human)

Compounds (5)

CompoundDescription
hydronium ion
iodineA nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
thyroxineThe major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)