PIP metabolism

Proteins (47)

Protein	Synonyms	Taxonomy
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta	PIP5KI-beta; PtdIns(4)P-5-kinase 1 beta; EC 2.7.1.68; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase beta; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha; Phosphatidylinositol 4-phosphate 5-kinase type I beta; PIP5KIbeta	Mus musculus (house mouse)
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	PIP5K1-alpha; PtdIns(4)P-5-kinase 1 alpha; EC 2.7.1.68; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha; Phosphatidylinositol 4-phosphate 5-kinase type I beta; PI4P5KIbeta	Mus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	PI3-kinase subunit beta; PI3K-beta; PI3Kbeta; PtdIns-3-kinase subunit beta; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; PtdIns-3-kinase subunit p110-beta; p110beta	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3	EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3	Mus musculus (house mouse)
Phosphatidylinositol 3-kinase regulatory subunit beta	PI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-beta	Mus musculus (house mouse)
Phosphatidylinositol 3-kinase regulatory subunit alpha	PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha	Mus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110delta	Mus musculus (house mouse)
1-phosphatidylinositol 3-phosphate 5-kinase	Phosphatidylinositol 3-phosphate 5-kinase; EC 2.7.1.150; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase; Serine-protein kinase PIKFYVE; 2.7.11.1; p235	Mus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; EC 2.7.1.137; EC 2.7.1.153; EC 2.7.1.154; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma; Phosph	Mus musculus (house mouse)
CDP-diacylglycerol--inositol 3-phosphatidyltransferase	EC 2.7.8.11; Phosphatidylinositol synthase; PI synthase; PtdIns synthase	Mus musculus (house mouse)
Phosphatidylinositol 4-kinase type 2-alpha	EC 2.7.1.67; Phosphatidylinositol 4-kinase type II-alpha	Mus musculus (house mouse)
Phosphatidylinositol 4-kinase beta	PI4K-beta; PI4Kbeta; PtdIns 4-kinase beta; EC 2.7.1.67	Mus musculus (house mouse)
Phosphatidylinositol 4-kinase type 2-beta	EC 2.7.1.67; Phosphatidylinositol 4-kinase type II-beta	Mus musculus (house mouse)
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	PIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; EC 2.7.1.68; Phosphatidylinositol 4-phosphate 5-kinase type I gamma; PIP5KIgamma	Mus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide-3-k	Mus musculus (house mouse)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	EC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2	EC 3.1.4.11; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-gamma-2; PLC-gamma-2	Mus musculus (house mouse)
Polyphosphoinositide phosphatase	EC 3.1.3.-; Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; SAC domain-containing protein 3	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1	EC 3.1.4.11; Phosphoinositide phospholipase C-delta-1; Phospholipase C-delta-1; PLC-delta-1	Mus musculus (house mouse)
Phosphatidylinositol polyphosphate 5-phosphatase type IV	72 kDa inositol polyphosphate 5-phosphatase; Inositol polyphosphate-5-phosphatase E; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; 3.1.3.36; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; 3.1.3.86	Mus musculus (house mouse)
Phosphoinositide-3-kinase-interacting protein 1	Calcineurin-regulated kringle domain-containing protein; Kringle domain-containing protein HGFL	Mus musculus (house mouse)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	EC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; Phosphatidylinositol 5-Phosphate 4-Kinase; PI5P4Kalpha; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PI(5)P 4-kinase type II alpha; PIP4KII-a	Mus musculus (house mouse)
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	EC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PtdIns(5)P-4-kinase isoform 2-beta	Mus musculus (house mouse)
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	EC 2.7.1.149; Phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gamma	Mus musculus (house mouse)
Phosphatidylinositol 3-kinase regulatory subunit gamma	PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIK	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2	EC 3.1.4.11; Phosphoinositide phospholipase C-eta-2; Phosphoinositide phospholipase C-like 4; PLC-L4; Phospholipase C-like protein 4; Phospholipase C-eta-2; PLC-eta2	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4	EC 3.1.4.11; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1	EC 3.1.4.11; Phosphoinositide phospholipase C-epsilon-1; Phospholipase C-epsilon-1; PLC-epsilon-1	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3	Mus musculus (house mouse)
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase	Type 1 PtdIns-4,5-P2 4-Ptase; EC 3.1.3.78; PtdIns-4,5-P2 4-Ptase I; Transmembrane protein 55B	Mus musculus (house mouse)
Phosphoinositide 3-kinase regulatory subunit 6	Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; p84 PI3K adapter protein; p84 PIKAP; p87 PI3K adapter protein; p87PIKAP	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1	EC 3.1.4.11; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; PLC-eta-1; Phospholipase C-like protein 3; PLC-L3	Mus musculus (house mouse)
Phosphoinositide 3-kinase regulatory subunit 5	PI3-kinase regulatory subunit 5; PI3-kinase p101 subunit; Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit; PtdIns-3-kinase regulatory subunit; PtdIns-3-kinase p101; p101-PI3K	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-gamma-1; PLC-gamma-1	Mus musculus (house mouse)
Type II inositol 3,4-bisphosphate 4-phosphatase	EC 3.1.3.66; Inositol polyphosphate 4-phosphatase type II	Mus musculus (house mouse)
Phosphatidylinositol 3-kinase catalytic subunit type 3	PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; EC 2.7.1.137; Phosphoinositide-3-kinase class 3	Mus musculus (house mouse)
Synaptojanin-1	EC 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1	Mus musculus (house mouse)
Myotubularin-related protein 3	EC 3.1.3.48; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1	EC 3.1.4.11; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1	Mus musculus (house mouse)
Phosphoinositide 3-kinase regulatory subunit 4	PI3-kinase regulatory subunit 4; EC 2.7.11.1	Mus musculus (house mouse)
Myotubularin-related protein 14	EC 3.1.3.-; mJumpy	Mus musculus (house mouse)
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase	Type 2 PtdIns-4,5-P2 4-Ptase; EC 3.1.3.78; PtdIns-4,5-P2 4-Ptase II; Transmembrane protein 55A	Mus musculus (house mouse)
Synaptojanin-2	EC 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2	Mus musculus (house mouse)
Phosphatidylinositol-3-phosphatase SAC1	EC 3.1.3.64; Phosphatidylinositol-4-phosphate phosphatase; Suppressor of actin mutations 1-like protein	Mus musculus (house mouse)
Inositol polyphosphate-4-phosphatase type I A	Inositol polyphosphate 4-phosphatase type I; Inositol polyphosphate 4-phosphatase-1; 4-Ptase-1; Type I inositol 3,4-bisphosphate 4-phosphatase; 3.1.3.66	Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1	EC 3.1.4.11; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-beta-1; PLC-beta-1	Mus musculus (house mouse)

Compounds (8)

Compound	Description
hydronium ion
Adenosine Triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
inositol	An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Cytidine Monophosphate	Cytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Phosphatidylinositol 4,5-Diphosphate	A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
phosphatidylinositol 4-phosphate