Pathways > PIP metabolism
Page last updated: 2024-10-06

PIP metabolism

Proteins (47)

ProteinSynonymsTaxonomy
Phosphatidylinositol 4-phosphate 5-kinase type-1 betaPIP5KI-beta; PtdIns(4)P-5-kinase 1 beta; EC 2.7.1.68; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase beta; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha; Phosphatidylinositol 4-phosphate 5-kinase type I beta; PIP5KIbetaMus musculus (house mouse)
Phosphatidylinositol 4-phosphate 5-kinase type-1 alphaPIP5K1-alpha; PtdIns(4)P-5-kinase 1 alpha; EC 2.7.1.68; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha; Phosphatidylinositol 4-phosphate 5-kinase type I beta; PI4P5KIbetaMus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformPI3-kinase subunit beta; PI3K-beta; PI3Kbeta; PtdIns-3-kinase subunit beta; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; PtdIns-3-kinase subunit p110-beta; p110betaMus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3Mus musculus (house mouse)
Phosphatidylinositol 3-kinase regulatory subunit betaPI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-betaMus musculus (house mouse)
Phosphatidylinositol 3-kinase regulatory subunit alpha PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaMus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformPI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110deltaMus musculus (house mouse)
1-phosphatidylinositol 3-phosphate 5-kinasePhosphatidylinositol 3-phosphate 5-kinase; EC 2.7.1.150; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase; Serine-protein kinase PIKFYVE; 2.7.11.1; p235Mus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; EC 2.7.1.137; EC 2.7.1.153; EC 2.7.1.154; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma; PhosphMus musculus (house mouse)
CDP-diacylglycerol--inositol 3-phosphatidyltransferaseEC 2.7.8.11; Phosphatidylinositol synthase; PI synthase; PtdIns synthaseMus musculus (house mouse)
Phosphatidylinositol 4-kinase type 2-alphaEC 2.7.1.67; Phosphatidylinositol 4-kinase type II-alphaMus musculus (house mouse)
Phosphatidylinositol 4-kinase betaPI4K-beta; PI4Kbeta; PtdIns 4-kinase beta; EC 2.7.1.67Mus musculus (house mouse)
Phosphatidylinositol 4-kinase type 2-betaEC 2.7.1.67; Phosphatidylinositol 4-kinase type II-betaMus musculus (house mouse)
Phosphatidylinositol 4-phosphate 5-kinase type-1 gammaPIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; EC 2.7.1.68; Phosphatidylinositol 4-phosphate 5-kinase type I gamma; PIP5KIgammaMus musculus (house mouse)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide-3-kMus musculus (house mouse)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologMus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2EC 3.1.4.11; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-gamma-2; PLC-gamma-2Mus musculus (house mouse)
Polyphosphoinositide phosphataseEC 3.1.3.-; Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; SAC domain-containing protein 3Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1EC 3.1.4.11; Phosphoinositide phospholipase C-delta-1; Phospholipase C-delta-1; PLC-delta-1Mus musculus (house mouse)
Phosphatidylinositol polyphosphate 5-phosphatase type IV72 kDa inositol polyphosphate 5-phosphatase; Inositol polyphosphate-5-phosphatase E; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; 3.1.3.36; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; 3.1.3.86Mus musculus (house mouse)
Phosphoinositide-3-kinase-interacting protein 1Calcineurin-regulated kringle domain-containing protein; Kringle domain-containing protein HGFLMus musculus (house mouse)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaEC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; Phosphatidylinositol 5-Phosphate 4-Kinase; PI5P4Kalpha; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PI(5)P 4-kinase type II alpha; PIP4KII-aMus musculus (house mouse)
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaEC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PtdIns(5)P-4-kinase isoform 2-betaMus musculus (house mouse)
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaEC 2.7.1.149; Phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gammaMus musculus (house mouse)
Phosphatidylinositol 3-kinase regulatory subunit gammaPI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIKMus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2EC 3.1.4.11; Phosphoinositide phospholipase C-eta-2; Phosphoinositide phospholipase C-like 4; PLC-L4; Phospholipase C-like protein 4; Phospholipase C-eta-2; PLC-eta2Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4EC 3.1.4.11; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1EC 3.1.4.11; Phosphoinositide phospholipase C-epsilon-1; Phospholipase C-epsilon-1; PLC-epsilon-1Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3Mus musculus (house mouse)
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphataseType 1 PtdIns-4,5-P2 4-Ptase; EC 3.1.3.78; PtdIns-4,5-P2 4-Ptase I; Transmembrane protein 55BMus musculus (house mouse)
Phosphoinositide 3-kinase regulatory subunit 6 Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; p84 PI3K adapter protein; p84 PIKAP; p87 PI3K adapter protein; p87PIKAPMus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1EC 3.1.4.11; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; PLC-eta-1; Phospholipase C-like protein 3; PLC-L3Mus musculus (house mouse)
Phosphoinositide 3-kinase regulatory subunit 5PI3-kinase regulatory subunit 5; PI3-kinase p101 subunit; Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit; PtdIns-3-kinase regulatory subunit; PtdIns-3-kinase p101; p101-PI3KMus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-gamma-1; PLC-gamma-1Mus musculus (house mouse)
Type II inositol 3,4-bisphosphate 4-phosphataseEC 3.1.3.66; Inositol polyphosphate 4-phosphatase type IIMus musculus (house mouse)
Phosphatidylinositol 3-kinase catalytic subunit type 3PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; EC 2.7.1.137; Phosphoinositide-3-kinase class 3Mus musculus (house mouse)
Synaptojanin-1EC 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1Mus musculus (house mouse)
Myotubularin-related protein 3EC 3.1.3.48; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1EC 3.1.4.11; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1Mus musculus (house mouse)
Phosphoinositide 3-kinase regulatory subunit 4PI3-kinase regulatory subunit 4; EC 2.7.11.1Mus musculus (house mouse)
Myotubularin-related protein 14EC 3.1.3.-; mJumpyMus musculus (house mouse)
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphataseType 2 PtdIns-4,5-P2 4-Ptase; EC 3.1.3.78; PtdIns-4,5-P2 4-Ptase II; Transmembrane protein 55AMus musculus (house mouse)
Synaptojanin-2EC 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2Mus musculus (house mouse)
Phosphatidylinositol-3-phosphatase SAC1EC 3.1.3.64; Phosphatidylinositol-4-phosphate phosphatase; Suppressor of actin mutations 1-like proteinMus musculus (house mouse)
Inositol polyphosphate-4-phosphatase type I AInositol polyphosphate 4-phosphatase type I; Inositol polyphosphate 4-phosphatase-1; 4-Ptase-1; Type I inositol 3,4-bisphosphate 4-phosphatase; 3.1.3.66Mus musculus (house mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 EC 3.1.4.11; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-beta-1; PLC-beta-1Mus musculus (house mouse)

Compounds (8)

CompoundDescription
hydronium ion
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Phosphatidylinositol 4,5-DiphosphateA phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
phosphatidylinositol 4-phosphate
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