Pathways > Negative regulation of MET activity
Page last updated: 2024-10-06
Negative regulation of MET activity
Proteins (8)
Protein | Synonyms | Taxonomy |
Hepatocyte growth factor receptor | HGF receptor; EC 2.7.10.1; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met | Homo sapiens (human) |
Epidermal growth factor receptor substrate 15 | Protein Eps15; Protein AF-1p | Homo sapiens (human) |
Receptor-type tyrosine-protein phosphatase eta | Protein-tyrosine phosphatase eta; R-PTP-eta; EC 3.1.3.48; Density-enhanced phosphatase 1; DEP-1; HPTP eta; Protein-tyrosine phosphatase receptor type J; R-PTP-J | Homo sapiens (human) |
Hepatocyte growth factor-regulated tyrosine kinase substrate | Hrs; Protein pp110 | Homo sapiens (human) |
Ubiquitin carboxyl-terminal hydrolase 8 | EC 3.4.19.12; Deubiquitinating enzyme 8; Ubiquitin isopeptidase Y; hUBPy; Ubiquitin thioesterase 8; Ubiquitin-specific-processing protease 8 | Homo sapiens (human) |
SH3 domain-containing kinase-binding protein 1 | CD2-binding protein 3; CD2BP3; Cbl-interacting protein of 85 kDa; Human Src family kinase-binding protein 1; HSB-1 | Homo sapiens (human) |
E3 ubiquitin-protein ligase CBL | EC 2.3.2.27; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; Signal transduction protein CBL | Homo sapiens (human) |
Leucine-rich repeats and immunoglobulin-like domains protein 1 | LIG-1 | Homo sapiens (human) |
Compounds (4)
Compound | Description |
Orthophosphate | |
adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |