Page last updated: 2024-10-06
Leloir Pathway
Proteins (6)
| Protein | Synonyms | Taxonomy |
|---|
| Galactokinase | EC 2.7.1.6; Galactose kinase | Saccharomyces cerevisiae S288C |
| Galactose-1-phosphate uridylyltransferase | Gal-1-P uridylyltransferase; EC 2.7.7.12; UDP-glucose--hexose-1-phosphate uridylyltransferase | Saccharomyces cerevisiae S288C |
| Phosphoglucomutase 1 | PGM 1; EC 5.4.2.2; Glucose phosphomutase 1 | Saccharomyces cerevisiae S288C |
| Phosphoglucomutase 2 | PGM 2; EC 5.4.2.2; D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase; Glucose phosphomutase 2 | Saccharomyces cerevisiae S288C |
| Bifunctional protein GAL10 | | Saccharomyces cerevisiae S288C |
| UTP--glucose-1-phosphate uridylyltransferase | EC 2.7.7.9; UDP-glucose pyrophosphorylase; UDPGP; UGPase | Saccharomyces cerevisiae S288C |
Compounds (11)
| Compound | Description |
|---|
| hydronium ion | |
| uridine diphosphate | A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. |
| galactose | An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood. |
| galactose | An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| uridine triphosphate | Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety. |
| galactose-1-phosphate | |
| uridine diphosphate galactose | A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose. |
| glucose-1-phosphate | RN given refers to (alpha-D-Glc)-isomer |
| Glucose-6-Phosphate | An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed) |