Page last updated: 2024-10-06

L-leucine biosynthesis

Proteins (7)

ProteinSynonymsTaxonomy
2-isopropylmalate synthaseEC 2.3.3.13; Alpha-IPM synthase; Alpha-isopropylmalate synthaseEscherichia coli K-12
Isopropylmalate/citramalate isomerase large subunitEC 4.2.1.33; EC 4.2.1.35; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; 4.2.1.31Methanocaldococcus jannaschii DSM 2661
Isopropylmalate/citramalate isomerase small subunitEC 4.2.1.33; EC 4.2.1.35; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; 4.2.1.31Methanocaldococcus jannaschii DSM 2661
3-isopropylmalate dehydratase small subunitEC 4.2.1.33; Alpha-IPM isomerase; IPMI; Isopropylmalate isomeraseLeptospira interrogans serovar Lai str. 56601
3-isopropylmalate dehydratase large subunitEC 4.2.1.33; Alpha-IPM isomerase; IPMI; Isopropylmalate isomeraseLeptospira interrogans serovar Lai str. 56601
Branched-chain-amino-acid aminotransferaseBCAT; EC 2.6.1.42; Transaminase BEscherichia coli K-12
Aromatic-amino-acid aminotransferaseARAT; AROAT; EC 2.6.1.57; Beta-methylphenylalanine transaminase; 2.6.1.107Escherichia coli K-12

Compounds (11)

CompoundDescription
hydronium ion
NADH
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
alpha-Ketoglutarate
2-keto-4-methylvalerate
alpha-keto-isovaleric acid
glutamate
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.