Page last updated: 2024-10-06
HDR through MMEJ (alt-NHEJ)
Proteins (10)
| Protein | Synonyms | Taxonomy |
|---|
| Nibrin | Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1 | Homo sapiens (human) |
| DNA polymerase theta | EC 2.7.7.7; DNA polymerase eta | Homo sapiens (human) |
| Breast cancer type 2 susceptibility protein | Fanconi anemia group D1 protein | Homo sapiens (human) |
| Double-strand break repair protein MRE11 | EC 3.1.-.-; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A | Homo sapiens (human) |
| DNA ligase 3 | EC 6.5.1.1; DNA ligase III; Polydeoxyribonucleotide synthase [ATP] 3 | Homo sapiens (human) |
| DNA repair protein RAD52 homolog | | Homo sapiens (human) |
| Flap endonuclease 1 | FEN-1; EC 3.1.-.-; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1 | Homo sapiens (human) |
| DNA endonuclease RBBP8 | EC 3.1.-.-; CtBP-interacting protein; CtIP; Retinoblastoma-binding protein 8; RBBP-8; Retinoblastoma-interacting protein and myosin-like; RIM; Sporulation in the absence of SPO11 protein 2 homolog; SAE2 | Homo sapiens (human) |
| DNA repair protein RAD50 | hRAD50; EC 3.6.-.- | Homo sapiens (human) |
| DNA repair protein XRCC1 | X-ray repair cross-complementing protein 1 | Homo sapiens (human) |
Compounds (3)
| Compound | Description |
|---|
| niacinamide | An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |