Page last updated: 2024-10-06
GDP-fucose biosynthesis
Proteins (6)
| Protein | Synonyms | Taxonomy |
|---|
| GDP-mannose 4,6 dehydratase | EC 4.2.1.47; GDP-D-mannose dehydratase; GMD | Homo sapiens (human) |
| Fucose-1-phosphate guanylyltransferase | EC 2.7.7.30; GDP-L-fucose diphosphorylase; GDP-L-fucose pyrophosphorylase | Homo sapiens (human) |
| L-fucose kinase | Fucokinase; EC 2.7.1.52 | Homo sapiens (human) |
| GDP-L-fucose synthase | EC 1.1.1.271; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; Protein FX; Red cell NADP(H)-binding protein; Short-chain dehydrogenase/reductase family 4E member 1 | Homo sapiens (human) |
| Fucose mutarotase | EC 5.1.3.29 | Homo sapiens (human) |
| GDP-fucose transporter 1 | Solute carrier family 35 member C1 | Homo sapiens (human) |
Compounds (10)
| Compound | Description |
|---|
| hydronium ion | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| gdp-4-keto-6-deoxymannose | |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| cytarabine | A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| fucopyranosyl phosphate | structure given in first source; RN given for (beta-L)-isomer |