Page last updated: 2024-10-06

GDP-fucose biosynthesis

Proteins (6)

ProteinSynonymsTaxonomy
GDP-mannose 4,6 dehydrataseEC 4.2.1.47; GDP-D-mannose dehydratase; GMDHomo sapiens (human)
Fucose-1-phosphate guanylyltransferaseEC 2.7.7.30; GDP-L-fucose diphosphorylase; GDP-L-fucose pyrophosphorylaseHomo sapiens (human)
L-fucose kinaseFucokinase; EC 2.7.1.52Homo sapiens (human)
GDP-L-fucose synthaseEC 1.1.1.271; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; Protein FX; Red cell NADP(H)-binding protein; Short-chain dehydrogenase/reductase family 4E member 1Homo sapiens (human)
Fucose mutarotaseEC 5.1.3.29Homo sapiens (human)
GDP-fucose transporter 1Solute carrier family 35 member C1Homo sapiens (human)

Compounds (10)

CompoundDescription
hydronium ion
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
gdp-4-keto-6-deoxymannose
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
cytarabineA pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
fucopyranosyl phosphatestructure given in first source; RN given for (beta-L)-isomer