Page last updated: 2024-10-06

FMO oxidises nucleophiles

Proteins (3)

ProteinSynonymsTaxonomy
Dimethylaniline monooxygenase [N-oxide-forming] 1EC 1.14.13.8; Dimethylaniline oxidase 1; Fetal hepatic flavin-containing monooxygenase 1; FMO 1Homo sapiens (human)
Dimethylaniline monooxygenase [N-oxide-forming] 2EC 1.14.13.8; Dimethylaniline oxidase 2; FMO 1B1; Pulmonary flavin-containing monooxygenase 2; FMO 2Homo sapiens (human)
Dimethylaniline monooxygenase [N-oxide-forming] 3EC 1.14.13.8; EC 1.14.14.73; Dimethylaniline oxidase 3; FMO II; FMO form 2; Hepatic flavin-containing monooxygenase 3; FMO 3; Trimethylamine monooxygenase; 1.14.13.148Homo sapiens (human)

Compounds (11)

CompoundDescription
hydronium ion
methimazoleA thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
tamoxifenOne of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
trimethyloxamineused in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamineassociated with egg taints - comparable to an egg having bad breath; degradation product of nitrogenous plant & animal substances; converted to free tertiary amine during putrefaction; detected in menstrual blood & urine stored at room temp; used as insect attractant; warming agent for gas; RN given refers to parent cpd; structure
tamoxifen n-oxide
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
creolinfrom refined coal tar oils