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zonisamide and Ache

zonisamide has been researched along with Ache in 7 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Research Excerpts

ExcerptRelevanceReference
" Based on the experience with carbamazepine, gabapentin, and lamotrigine, these newer AEDs are being investigated for the management of neuropathic pain."8.82Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. ( Guay, DR, 2003)
"We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively."7.74Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008)
"We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide."7.72Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004)
"Zonisamide (1,2-benzisoxazole-3-methanesulfonamide) is a novel anti-seizure medication approved for use in the United States as adjunct therapy in the treatment of partial seizures in adults with epilepsy."7.72Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital. ( Hasegawa, H, 2004)
"Zonisamide is an antiepileptic drug used as adjunctive therapy for refractory partial seizures in adults."6.43Zonisamide: review of its use in epilepsy therapy. ( Zareba, G, 2005)
" Based on the experience with carbamazepine, gabapentin, and lamotrigine, these newer AEDs are being investigated for the management of neuropathic pain."4.82Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. ( Guay, DR, 2003)
"We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively."3.74Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008)
" We have evaluated the effects and investigated the possible mechanisms of action of zonisamide, an antiepileptic drug, on thermal hyperalgesia and tactile allodynia in a murine chronic pain model that was prepared by partial ligation of the sciatic nerve."3.73Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse. ( Honda, M; Ono, H; Sakaue, A; Takasu, K; Tanabe, M, 2005)
"We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide."3.72Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004)
"Zonisamide (1,2-benzisoxazole-3-methanesulfonamide) is a novel anti-seizure medication approved for use in the United States as adjunct therapy in the treatment of partial seizures in adults with epilepsy."3.72Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital. ( Hasegawa, H, 2004)
"Zonisamide is an antiepileptic drug used as adjunctive therapy for refractory partial seizures in adults."2.43Zonisamide: review of its use in epilepsy therapy. ( Zareba, G, 2005)
"Gabapentin has demonstrated efficacy, specifically in painful diabetic neuropathy and postherpetic neuralgia."2.41Use of anticonvulsants for treatment of neuropathic pain. ( Backonja, MM, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tanabe, M2
Murakami, T1
Ono, H2
Backonja, MM1
Takahashi, Y1
Hashimoto, K1
Tsuji, S1
Hasegawa, H1
Guay, DR1
Sakaue, A1
Takasu, K1
Honda, M1
Zareba, G1

Reviews

3 reviews available for zonisamide and Ache

ArticleYear
Use of anticonvulsants for treatment of neuropathic pain.
    Neurology, 2002, Sep-10, Volume: 59, Issue:5 Suppl 2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2002
Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain.
    The American journal of geriatric pharmacotherapy, 2003, Volume: 1, Issue:1

    Topics: Aged; Analgesics, Non-Narcotic; Animals; Carbamazepine; Clinical Trials as Topic; Dose-Response Rela

2003
Zonisamide: review of its use in epilepsy therapy.
    Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41, Issue:9

    Topics: Animals; Anticonvulsants; Biological Availability; Child; Child, Preschool; Drug Interactions; Epile

2005

Other Studies

4 other studies available for zonisamide and Ache

ArticleYear
Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Inflammation; Isoxazo

2008
Successful use of zonisamide for central poststroke pain.
    The journal of pain, 2004, Volume: 5, Issue:3

    Topics: Anticonvulsants; Calcium Channel Blockers; Calcium Channels, T-Type; Cerebral Infarction; Diabetes C

2004
Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital.
    Current medical research and opinion, 2004, Volume: 20, Issue:5

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Chronic Disease; Epilepsy; Humans; Isoxazoles; Male; Middl

2004
Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 372, Issue:2

    Topics: Animals; Antioxidants; Central Nervous System; Disease Models, Animal; Dose-Response Relationship, D

2005