Page last updated: 2024-11-05
zonisamide and Ache
zonisamide has been researched along with Ache in 7 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Based on the experience with carbamazepine, gabapentin, and lamotrigine, these newer AEDs are being investigated for the management of neuropathic pain." | 8.82 | Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. ( Guay, DR, 2003) |
| "We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively." | 7.74 | Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008) |
| "We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide." | 7.72 | Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004) |
| "Zonisamide (1,2-benzisoxazole-3-methanesulfonamide) is a novel anti-seizure medication approved for use in the United States as adjunct therapy in the treatment of partial seizures in adults with epilepsy." | 7.72 | Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital. ( Hasegawa, H, 2004) |
| "Zonisamide is an antiepileptic drug used as adjunctive therapy for refractory partial seizures in adults." | 6.43 | Zonisamide: review of its use in epilepsy therapy. ( Zareba, G, 2005) |
| " Based on the experience with carbamazepine, gabapentin, and lamotrigine, these newer AEDs are being investigated for the management of neuropathic pain." | 4.82 | Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. ( Guay, DR, 2003) |
| "We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively." | 3.74 | Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008) |
| " We have evaluated the effects and investigated the possible mechanisms of action of zonisamide, an antiepileptic drug, on thermal hyperalgesia and tactile allodynia in a murine chronic pain model that was prepared by partial ligation of the sciatic nerve." | 3.73 | Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse. ( Honda, M; Ono, H; Sakaue, A; Takasu, K; Tanabe, M, 2005) |
| "We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide." | 3.72 | Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004) |
| "Zonisamide (1,2-benzisoxazole-3-methanesulfonamide) is a novel anti-seizure medication approved for use in the United States as adjunct therapy in the treatment of partial seizures in adults with epilepsy." | 3.72 | Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital. ( Hasegawa, H, 2004) |
| "Zonisamide is an antiepileptic drug used as adjunctive therapy for refractory partial seizures in adults." | 2.43 | Zonisamide: review of its use in epilepsy therapy. ( Zareba, G, 2005) |
| "Gabapentin has demonstrated efficacy, specifically in painful diabetic neuropathy and postherpetic neuralgia." | 2.41 | Use of anticonvulsants for treatment of neuropathic pain. ( Backonja, MM, 2002) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Tanabe, M | 2 |
| Murakami, T | 1 |
| Ono, H | 2 |
| Backonja, MM | 1 |
| Takahashi, Y | 1 |
| Hashimoto, K | 1 |
| Tsuji, S | 1 |
| Hasegawa, H | 1 |
| Guay, DR | 1 |
| Sakaue, A | 1 |
| Takasu, K | 1 |
| Honda, M | 1 |
| Zareba, G | 1 |
Reviews
3 reviews available for zonisamide and Ache
| Article | Year |
|---|---|
Use of anticonvulsants for treatment of neuropathic pain.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; | 2002 |
Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain.
Topics: Aged; Analgesics, Non-Narcotic; Animals; Carbamazepine; Clinical Trials as Topic; Dose-Response Rela | 2003 |
Zonisamide: review of its use in epilepsy therapy.
Topics: Animals; Anticonvulsants; Biological Availability; Child; Child, Preschool; Drug Interactions; Epile | 2005 |
Other Studies
4 other studies available for zonisamide and Ache
| Article | Year |
|---|---|
Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Inflammation; Isoxazo | 2008 |
Successful use of zonisamide for central poststroke pain.
Topics: Anticonvulsants; Calcium Channel Blockers; Calcium Channels, T-Type; Cerebral Infarction; Diabetes C | 2004 |
Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Chronic Disease; Epilepsy; Humans; Isoxazoles; Male; Middl | 2004 |
Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse.
Topics: Animals; Antioxidants; Central Nervous System; Disease Models, Animal; Dose-Response Relationship, D | 2005 |