Page last updated: 2024-08-23

zidovudine and HIV

zidovudine has been researched along with HIV in 594 studies

*HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. [MeSH]

Research

Studies (594)

TimeframeStudies, this research(%)All Research%
pre-1990127 (21.38)18.7374
1990's328 (55.22)18.2507
2000's89 (14.98)29.6817
2010's39 (6.57)24.3611
2020's11 (1.85)2.80

Authors

AuthorsStudies
Balzarini, J; Bergstrom, DE; De Clercq, E; Mott, AW; Swartling, DJ1
Crawford-Ruth, D; Maag, H; McRoberts, MJ; Prisbe, EJ; Rydzewski, RM; Verheyden, JP1
Montgomery, JA; Riggs, RM; Secrist, JA; Tiwari, KN1
Andries, K; Breslin, HJ; Fedde, CL; Kukla, MJ; Miranda, M; Pauwels, R; Raeymaekers, A; Scott, MK; Sherrill, RG; Van Gelder, J1
Aoki, S; Driscoll, JS; Ford, H; Kelley, JA; Kojima, E; Mitsuya, H; Murakami, K; Shirasaka, T; Yoshioka, H1
Aoki, S; Barchi, JJ; Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T1
Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E1
Brankovan, V; Ghazzouli, I; Mansuri, MM; Martin, JC; Sterzycki, RZ1
Bennett, SM; Nguyen-Ba, N; Ogilvie, KK1
Hua, M; Vince, R1
Balzarini, J; De Clercq, E; Hiebl, J; Zbiral, E1
Clement, J; Erickson, J; Hayashi, S; Herrin, T; Kern, E; Norbeck, DW; Plattner, JJ; Rosenbrook, W; Sham, H; Swanson, R1
Aggarwal, SK; Agrawal, KC; Gogu, SR; Rangan, SR1
Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A1
Bhadti, VS; Boudinot, FD; Chu, CK; Doshi, KJ; Etse, JT; Gallo, JM; Schinazi, RF1
August, EM; Brankovan, V; Ghazzouli, I; Hitchcock, MJ; Lin, TS; Mansuri, MM; Prusoff, WH; Sommadossi, JP; Starrett, JE; Sterzycki, RZ1
Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Janssen, G; Pauwels, R; Van Aerschot, A1
Chu, CK; Guo, JY; Lin, TS; Prusoff, WH; Schinazi, RF; Xiang, JN1
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H1
Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R1
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH1
Cappellacci, L; De Montis, A; Franchetti, P; Grifantini, M; La Colla, P; Loi, AG; Piras, G; Sheikha, GA1
Drach, JC; Kern, ER; Krawczyk, SH; Kucera, LS; Nassiri, MR; Ptak, RG; Townsend, LB; Wotring, LL1
Balani, SK; Ciccarone, TM; Condra, JH; Emini, EA; Goldman, ME; Greenlee, WJ; Kauffman, LR; MacTough, SC; Rooney, CS; Williams, TM1
Boulanger, WA; Chen, W; Cibulski, M; Flavin, MT; Flavin, TM; Greenwood, EM; Hughes, SH; Khilevich, A; Kucherenko, A; Lin, L; Pengsuparp, T; Pezzuto, JM; Rizzo, JD; Sheinkman, AK; Shone, RL; Vilaychack, V; Xu, ZQ1
Bastow, KF; Cosentino, LM; Lee, KH; Wang, HK1
Balzarini, J; Cahard, D; De Clercq, E; McGuigan, C; Sheeka, HM1
Chang, FR; Lee, KH; Lin, JY; Wu, YC; Yang, PY1
Aubertin, A; Beltran, T; Egron, D; Gosselin, G; Imbach, J; Lefebvre, I; Périgaud, C; Pompon, A1
Gochfeld, DJ; Hamann, MT1
Hong, JH; Kim, A1
Baba, M; Cheng, YC; Dutschman, GE; Grill, SP; Hu, R; Lam, W; Paintsil, E; Tanaka, H1
Barreca, ML; Benkestock, K; Chimirri, A; Christ, F; De Luca, L; Debyser, Z; Eneroth, A; Ferro, S; Hombrouck, A; Johansson, NG; Michiels, M; Noppe, W; Sahlberg, BL; Van Remoortel, B; Vrang, L; Witvrouw, M1
Cecchetti, V; Daelemans, D; Manfroni, G; Massari, S; Pannecouque, C; Sabatini, S; Tabarrini, O1
Gosselin, G; Hamann, M; Liuzzi, M; Musiu, C; Pierra, C; Sommadossi, JP; Storer, R; Vargiu, L1
Boryski, J; Collu, G; Kraszewski, A; La Colla, P; Loddo, R; Romanowska, J; Sanna, G; Secci, B; Stawiński, J; Szymańska-Michalak, A1
Asaftei, S; De Clercq, E1
Ahmed, N; Bhutani, KK; Brahmbhatt, KG; Mitra, D; Sabde, S; Singh, IP1
Azas, N; Casano, G; Dumètre, A; Hutter, S; Pannecouque, C; Robin, M1
Chen, YG; Dong, JY; Gao, YX; Shen, KZ; Song, HC; Sun, R; Wang, CR; Xu, YB1
Coltart, DM; Garnsey, MR; Kwiek, JJ; Matous, JA1
Chiba, J; Hashimoto, C; Komoriya, M; Murakami, T; Narumi, T; Nomura, W; Suzuki, S; Tamamura, H; Tanaka, T; Wu, H; Yamamoto, N1
Geng, Y; Li, Y; Liu, Y; Qiao, W; Tan, J; Wang, L; Wang, M; Wang, Q; Wang, Z; Yao, X1
Ilina, T; Myshakina, NS; Parniak, MA; Sirivolu, VR; Vernekar, SK; Wang, Z1
Aldern, KA; Beadle, JR; Broker, TR; Buckheit, RW; Chow, LT; Harden, EA; Hartman, T; Hostetler, KY; Keith, KA; Prichard, MN; Valiaeva, N; Yang, G; Yu, JH1
Camarasa, MJ; de Castro, S1
Chen, FE; Gu, SX; Liu, GY; Meng, G; Pannecouque, C; Tang, JF; Wu, FS; Xiao, T; Xu, ZQ; Zhu, YY1
Fujino, M; Kaneko, M; Kobayakawa, T; Murakami, T; Owusu, KB; Tamamura, H; Tsuji, K; Wang, R; Yamamoto, N1
De Clercq, E; Gao, P; Liu, X; Pannecouque, C; Song, S; Sun, L; Wang, Z; Zhan, P; Zhang, J1
Ahmed, FA; Chen, CH; Hossain, GM; Kashiwada, Y; Lee, KH; Nakatani, M; Takahashi, S; Tanaka, N; Yoshino, Y1
Motiee, F; Sohrabi, MR; Valaee, M1
Behl, S; Cardenas, MC; Chakraborty, R; Enninga, EAL; Farnan, S; Gray, CM; Hamel, BL; Johnson, E; Littlefield, DR; Mejia Plazas, MC; Punia, S; Sintim-Aboagye, E; Temesgen, Z; Theiler, R1
Eleje, GU; Ikechebelu, JI; Nwagha, UI; Okafor, HU; Ugwu, AO; Ugwu, EO; Umeh, UA1
George, PE; Mercedes, R; Nabukeera-Barungi, N; Otto, SBJ1
Alejandria, M; Arcangel, L; Arevalo, GM; Ching, PR; Destura, R; Dungca, NT; Leyritana, K; Lim, J; Mendoza, KAR; Palaypayon, NS; Peñalosa-Ramos, C; Salvana, EMT; Samonte, GMJ; Schwem, BE; Solante, R; Tactacan-Abrenica, RJ; Telan, E; Tonga, AD; Trinidad, LF1
Jianwei, L; Menghua, W; Qinwei, Y; Xin, Z; Yu, Z1
Basu, A; Biswas, A; Das, BK; Nischal, N; Soneja, M; Sood, R; Wig, N1
Joshy, KS; Laly, AP; Nandakumar, K; Sabu, T; Snigdha, S; Susan, MA1
Chen, X; Fairley, CK; He, J; Jing, J; Mao, L; Sasadeusz, J; Su, S; Wei, X; Zeng, H; Zhang, L1
Balachandra, S; Dinh, TH; Kilmarx, PH; Mugurungi, O; Mushavi, A; Nyakura, J; Shambira, G; Shiraishi, RW; Tippett Barr, B; Tshimanga, M; Zinyowera, S1
Kan, W; Leng, X; Liao, L; Liu, P; Ruan, Y; Shao, Y; Wang, J; Xing, H; Xu, W; Yan, J; You, Y; Zuo, Z1
Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF1
Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K1
Abbas, SQ; Abro, AG; Baig-Ansari, N; Kazi, MA; Mir, F; Qamar, FN; Rizvi, A; Zaidi, AK1
Holla, P; Jameel, S; Munshi, SU; Panda, H; Rewari, BB1
Imai, Y; Kawamoto, M; Kohara, N; Sekiya, H; Togo, M; Yoshimura, H1
Bader, J; Glass, TR; Klimkait, T; Labhardt, ND; Lejone, TI; Puga, D; Ringera, I1
Cai, W; Caughey, B; Chung, C; Dai, Z; Hu, F; Lan, Y; Li, L; Tang, X; Zhang, K1
Belyhun, Y; Liebert, UG; Maier, M1
Bacha, T; Olana, T; Tadesse, BT; Worku, W1
Boulle, A; Cohen, K; Davies, MA; de Waal, R; Fortuin-de Smidt, M; Igumbor, EU; Maartens, G; Stinson, K; Technau, KG1
Hamada, Y1
Gray, GE; Saloojee, H1
Caffrey, M; Cook, JL; Ghassemi, M; Konrad, M; Lavie, A; Monnerjahn, C; Novak, RM; Sekulic, N; Su, Y1
Hamprecht, K; Schott, H; Schott, S; Schott, TC; Schwendener, RA1
Adams, E; Baert, L; Hoogmartens, J; Pendela, M; Rosier, J; Van den Mooter, G; Van Gyseghem, E1
Huisinga, W; von Kleist, M1
Barr, EA; Davies, JK; Forster-Harwood, J; Kinzie, K; Levin, MJ; McFarland, EJ; Pappas, J; Paul, SM; Salbenblatt, CR; Soda, E; Vazquez, A; Weinberg, A1
Ammann, AJ1
Bruun, J; Clotet, B; Cozzi-Lepri, A; Eg Hansen, AB; Horban, A; Katlama, C; Lundgren, JD; Martinez-Picado, J; Monforte, Ad; Phillips, AN1
Cihlar, T; Ray, AS1
Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW1
Davey, RT; Dewar, R; Follmann, DA; Herpin, B; Huang, CY; Kovacs, J; Lane, HC; Masur, H; Metcalf, JA; Polis, MA; Shah, A; Shen, J; Tavel, JA; Vasudevachari, MB1
Brenner, B1
Avihingsanon, A; Belloso, WH; Boesecke, C; Cooper, DA; Duncombe, C; Emery, S; Gazzard, B; Li, L; Molina, JM; Petoumenos, K; Puls, RL; Srasuebkul, P1
Bachani, D; Chan, PL; Deshpande, A; Rajasekaran, S; Rewari, BB; Srikantiah, P1
Dhlomo, S; Emery, S; Grandits, G; Khabo, P; Khanyile, T; Komati, S; Magongoa, D; Naidoo, LC; Neaton, JD; Polis, M; Qolohle, D; Ratsela, A1
Biwolé-Sida, M; Bork, K; Coudray, M; Cournil, A; Delaporte, E; Essomba, CN; Kouanfack, C; Laurent, C; Tonfack, CA1
Dugange, F; Harms, G; Jordan-Harder, B; Kirsten, I; Kunz, A; Sewangi, J; Theuring, S; Ziske, J1
Achalapong, J; Beck, IA; Britto, P; Chotivanich, N; Cressey, TR; Frenkel, L; Jourdain, G; Maupin, R; Mirochnick, M; Ngo-Giang-Huong, N; Prommas, S; Puthanakit, T; Rasri, W; Roongpisuthipong, A; Shapiro, DE; Van Dyke, RB; Yuthavisuthi, P1
Aurpibul, L; Capparelli, E; Chokephaibulkit, K; Cressey, TR; Eksaengsri, A; Hongsiriwon, S; Kabat, B; Limwongse, C; McIntosh, K; Muresan, P; Ngampiyaskul, C; Sirisanthana, V; Smith, ME; Toye, M; Wittawatmongkol, O; Yogev, R1
Selwood, D1
Hirase, C; Maeda, Y; Matsumura, I; Miyatake, J; Morita, Y; Sasakawa, A; Yamaguchi, T1
Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S1
Kemapunmanus, M; Nittayananta, W; Sriplung, H; Talungchit, S; Yangngam, S1
Armishaw, J; Cameron, PU; Chuah, J; Cooper, DA; Crowe, SM; Fairley, C; Gouillou, M; Hearps, A; Koelsch, KK; Leeansyah, E; Lewin, SR; Liu, JP; Pierce, AB; Smit, de V; Solomon, A; Spelman, T; Tennakoon, S; Velayudham, P1
Adachi, M; Antonelli, G; Bambacioni, F; Focher, F; Riva, E; Sampath, J; Scagnolari, C; Schuetz, JD; Turriziani, O1
Allen, TM; Kelleher, AD; Walker, BD; Zaunders, J1
Antonelli, G; Bambacioni, F; Bellomi, F; Focher, F; Gentile, M; Scagnolari, C; Turriziani, O1
Dierich, MP; El Attal, R; Falkensammer, B; Müllauer, B; Parson, W; Sarcletti, M; Stoiber, H1
Aboulker, JP; Brun-Vézinet, F; Descamps, D; Flandre, P; Harel, M; Izopet, J; Joly, V; Lastère, S; Meiffrédy, V; Peytavin, G; Tamalet, C; Yéni, P; Zeng, AF1
Bhatta, MP; Lewis, J; Nichols, SA; Vermund, SH1
Paul, SM1
Misra, K; Shukla, V; Watal, G1
Balzarini, J; De Clercq, E; Kaminska, B; Orzeszko, A1
Fisher, RL; Hernandez, JE; Hessenthaler, SM; Lonergan, JT; McComsey, GA; Sension, MG; Shalit, P; Ward, DJ; Williams, VC1
Pendergrass, S; Qazi, S; Uckun, FM; Venkatachalam, TK1
Cortina-Borja, M; Gray, L; Newell, ML1
Brew, BJ; Pemberton, L; Ray, J1
Fleming, RA; Furman, PA; Hes, J; Ishaq, KS; Iyer, N; Kucera, LS; Morris-Natschke, SL1
Goldschmidt, V; Marquet, R1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M1
Aarnoutse, RE; Burger, DM; Verweij-van Wissen, CP1
Antonelli, G; Antonelli, L; Butera, O; Gianotti, N; Girardi, E; Iaiani, G; Lazzarin, A; Mazzi, R; Parisi, SG; Turriziani, O1
Engels, JW; Lazrek, HB; Rochdi, A; Taourirte, M; Vasseur, JJ1
Boryski, J; Collu, G; Giliberti, G; Kraszewski, A; La Colla, P; Loddo, R; Sanna, G; Stawiński, J; Szymańska, A; Szymczak, M1
Arribas, JR; Campo, RE; Cheng, AK; Chuck, S; DeJesus, E; Enejosa, J; Gallant, JE; Gazzard, B; Lu, B; McColl, D; Pozniak, AL; Toole, JJ1
Jenny-Avital, ER1
Brown, J; Heffernan-Vacca, S; Millery, M; Neu, N; Stimell, M1
Andreotti, M; Ceffa, S; Cusato, M; Germano, P; Giuliano, M; Guidotti, G; Liotta, G; Loureiro, S; Mancini, MG; Marazzi, MC; Palombi, L; Pirillo, MF; Regazzi, M; Vella, S; Villani, P1
Blauvelt, A; Hartley, O; Root, MJ; Sugaya, M1
Dubé, MP; Grinspoon, SK; Komarow, L; Mulligan, K; Parker, RA; Robbins, GK; Roubenoff, R; Tebas, P1
Calmy, A; Ditangco, R; Huffam, SE; Kaldor, JM; Saphonn, V; Srasuebkul, P; Zhou, J1
Gulick, RM; Kuritzkes, DR; Ribaudo, HJ1
Anderson, AM; Bartlett, JA; Kosinski, AS1
Eron, JJ; Fiscus, SA; Foust, E; Kuruc, J; Leone, PA; McCoy, SI; Patterson, KB; Pilcher, CD; Williams, D; Wolf, L1
Carlson, M; Goldenberg, DT; Gupta, A; Holland, GN; Kuppermann, BD; Novack, RD; Read, RW; Shiramizu, KM; Vaudaux, JD; Yu, F1
Arizcorreta-Yarza, A; Collado, A; Fernández-Fuertes, E; Girón-González, JA; González-Serrano, M; López-Cortés, LF; Lozano, F; Macías, J; Merino, D; Mira, JA; Pineda, JA; Ríos-Villegas, MJ; Rivero, A; Torres-Tortoso, M; Valera-Bestard, B1
Fromentin, E; Hernandez-Santiago, BI; Hurwitz, SJ; Obikhod, A; Schinazi, RF1
Anglaret, X; Dabis, F; Dakoury-Dogbo, N; Diakite, N; Duvignac, J; Grundmann, C; Karcher, S; Kouadio, B; Marlink, R; Seyler, C; Toure, S; Traore, M1
Fauci, AS1
Duesberg, PH2
Hirata, A; Itoh, W; Sugawara, I1
Kurimura, T; Sakamoto, T; Tsuchie, H1
Connell, EV; Hsu, MC; Richman, DD1
Efron, B; Katzenstein, DA; Kozal, MJ; Kroodsma, K; Merigan, TC; Shafer, RW; Winters, MA1
Kim, B; Loeb, LA2
Cupler, EJ; Dalakas, MC; Danon, MJ; Hench, K; Jay, C; Ropka, M1
Domanski, MJ; Egan, D; Follmann, DA; Pizzo, PA; Scalise, PP; Sloas, MM; Tucker, EE1
Bryson, YJ; Deveikis, A; Frenkel, LM; Keller, M; Nielsen, K; Sim, MS; Stiehm, ER; Wei, LS1
Clayton, DA; Eriksson, S; Xu, B1
Gibb, DM; Newell, ML1
Katzenstein, DA; Kozal, MJ; Merigan, TC; Shafer, RW; Winters, MA1
Rennie, J1
Andrieu, JM; Lu, W1
Cohen, J4
Richman, DD9
Mayer, V; Schmidtmayerová, H1
Hansen, JE; Mathiesen, LR; Nielsen, C; Nielsen, JO; Sørensen, AM1
Ellis, MN; Felgner, J; Felgner, PL; Gardner, MF; Hostetler, KY; Ricci, J; Richman, DD; Selleseth, DW; Sridhar, CN1
Boyer, E; Dong, H; Eastman, S; Holodniy, M; Kolberg, J; Margolis, D; Mole, L; Moss, J; Urdea, M1
Medina, D; Strair, R1
Anderson, LS; Cantu, AA; Drake, RR; Jones, R; Mao, F; Moyer, MP; Radominska, A; Rechtin, TM1
Bindels, PJ; Coutinho, RA; Krol, A; Miedema, F; Roos, M; van den Hoek, JA; Veenstra, J1
Dolezal, J; Hraba, T1
Abdel-Rahman, RM; el-Baz, I; Fawzy, M; Seada, M2
Cline, FA1
Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P1
Fischl, MA; Lai, S; Meng, TC; Resnick, L; Richman, DD; Spector, SA1
Bratt, G; Broliden, PA; Eriksson, L; Gilljam, G; Hinkula, J; Levén, B; Nordlund, S; Persson, C; Volvovitz, F; Wahren, B1
D'Agostini, C; Favalli, C; Garaci, E; Grelli, S; Mastino, A; Perroni, L; Rocchi, G; Soscia, F1
Frost, SD; McLean, AR1
Borkowsky, W; Bourinbaiar, AS; Krasinski, K; Lee-Huang, S1
Davison, FD; Kaczmarski, RS; Mufti, GJ; Pozniak, A; Sutherland, S1
Lüthy, R1
Blunt, JW; Boyd, MR; Bringmann, G; Buckheit, RW; Cardellina, JH; Cragg, GM; Hallock, YF; Manfredi, KP; McMahon, JB; Schäffer, M1
Hostetler, KY; Kroneman, E; Kumar, R; Richman, DD; Sridhar, CN; van den Bosch, H; van Wijk, GM1
Antonelli, G; Arici, C; Del Poggio, P; Dianzani, F; Gregis, GP; Ippolito, G; Riva, E1
Aubertin, AM; Benzaria, S; Girardet, JL; Gosselin, G; Imbach, JL; Kirn, A; Maury, G; Pelicano, H; Perigaud, C1
Mathé, G; Pontiggia, P1
Aquaro, S; Balestra, E; Billich, A; Caliò, R; Peichl, P; Perno, CF; Rosenwirth, B; Villani, N1
Cinque, P; Coen, M; Gallo, L; Gringeri, A; Landonio, G; Lazzarin, A; Meraviglia, P; Nosari, AM; Quirino, T; Ruggieri, A1
Holodniy, M; Katzenstein, D; Kozal, M; Merigan, TC; Montoya, J; Ragni, M; Shafer, R; Winters, M1
Maag, H; Nelson, JT; Prisbe, EJ; Steiner, JL1
Bergé, P; Mildvan, D; Salgo, M; St Clair, M; Starrett, S1
Baumgarten, R2
Magnuson, T; Mourton, T; Toltzis, P1
Hall, ET; Kuchta, RD; Melançon, P; Yan, JP1
Amici, C; Beninati, S; Bergamini, A; Capozzi, M; Dini, L; Ghibelli, L; Milanese, G; Pesce, CD; Salanitro, A; Wagner, T1
Armbrecht, C; Hengels, KJ; Jablonowski, H; Manegold, C; Mauss, S; Szelenyi, H1
Cretton, EM; Hitchcock, MJ; Kaul, S; Kidd, LB; McClure, HM; Sommadossi, JP; Zhou, Z1
Dawson, SC; Landsman, D; Lane, HC; Salzman, NP; Zhang, YM1
Becker, NG; Motika, M1
Andrews, JC; Hamilton, JD; Hartigan, PM; Simberkoff, MS; St Clair, MH; Vavro, CL1
Anderson, C1
Burrell, C; Kok, T; Li, P1
Cremoni, L; D'Amico, P; Grassi, MG; Milazzo, F; Vaira, LL1
Maddox, J2
Baker, CJ; Bremer, JW; Dimitrov, DH; Doyle, M; Hollinger, FB; Kline, MW; Shearer, WT1
Soeiro, R1
Erickson, J; Ford, H; Gulnik, S; Hayashi, H; Kageyama, S; Mimoto, T; Murakawa, Y; Nomizu, M; Shirasaka, T; Takada, K1
Groopman, JE; Kunzi, MS1
Lee, CA; Phillips, AN; Sabin, CA1
Andrews, W; Madhavankutty, K; Shyamasundar, K1
Jablonowski, H1
Baruch, A; Bassett, RL; Collier, AC; Coombs, RW; Corey, L; Facey, K; Friedman, HM; Hooper, C; Jones, M; McAuliffe, VJ; Merigan, TC; Reichman, RC; Schoenfeld, DA; Timpone, J; Whitacre, C1
Bartlett, JA; Bilello, J; Cohen, OJ; Cohn, J; Fauci, AS; Fox, CH; Graziosi, C; Holodniy, M; Lalezari, J; McMahon, D; Niu, M; Novak, R; Orenstein, JM; Pantaleo, G; Pavlakis, GN; Schnittman, S; Steigbigel, RT1
Benveniste, O; Clayette, P; Dormont, D; Frétier, P; Le Grand, R; Le Naour, R; Noack, O; Théodoro, F; Vaslin, B1
Bryant, M; Clare, M; DeCrescenzo, G; Dillard, R; Getman, D; Heintz, R; Houseman, K; Lansky, D; Marr, J; Smidt, M1
Buckheit, R; Decker, W; Elder, C; Grever, M; Hollingshead, M; Malspeis, L; Mayo, J; Roberson, J1
Jagannadh, B; Kunwar, AC; Reddy, DV1
Coutinho, RA; de Ronde, A; de Rooij, ER; Goudsmit, J1
Bartlett, JA; Benoit, SL; Ehmann, WC; Fallon, MA; Johnson, VA; Quinn, JB; Rubin, M; Self, PL; Sepulveda, GE; Tsoukas, C1
Kalnina, LB; Kaplina, EN; Lavrukhina, LA; Nosik, DN; Nosik, NN; Vaĭnberg, IP1
Rowe, PM1
Rosenthal, C1
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Balachandran, R; Enrico, A; Gupta, P; Ho, M; Rinaldo, C1
Morse, GD; Olson, J; Plank, C; Portmore, A; Reichman, RC; Taylor, C1
Banks, S; Baseler, MW; Deyton, L; Falloon, J; Kirk, LE; Kovacs, JA; Lane, HC; Masur, H; Salzman, NP; Walker, RE1
Abraham, NG; Ahmed, T; Brown, AC; Bucher, D; Distenfeld, A; Levere, RD; Lutton, JD; Niranjan, U1
Agrawal, KC; Beckman, BS; Gogu, SR1
Hitchcock, MJ; Ho, HT1
Engle, K; Field, M; Gillespie, DH; Mitchell, WM; Montefiori, DC; Pellegrino, MG; Robinson, WE1
Balzarini, J; De Clercq, E; Desmyter, J; Goubau, P; Herdewijn, P; Pauwels, R; Vandeputte, M; Vanderhaeghe, H1
Carson, DA; Kornbluth, RS; Richman, DD1
Baba, M; Balzarini, J; Broder, S; de Clercq, E; Herdewijn, P; Johns, DG; Pauwels, R1
Biron, K; Lin, JC; Pagano, JS; Smith, MC; Zhang, ZX1
Broder, S; Mitsuya, H1
Broder, S; Yarchoan, R2
Chou, TC; Coleman, LA; Durno, AG; Hirsch, MS; Kaplan, JC; Paradis, TJ; Schooley, RT; Vogt, MW1
Cooney, DA; Gartner, S; Gerrard, TL; Hao, Z; Hartman, NR; Johns, DG; Perno, CF; Popovic, M; Wilson, YA; Yarchoan, R1
Brownell, J; Daluge, S; Hua, M; Kiser, R; Lavelle, GC; Lee, FC; Qualls, J; Shannon, WM; Vince, R; Weislow, OS1
Fitz-Gibbon, L; Tremblay, M; Wainberg, MA1
Balfour, HH; Cantrill, HL; Erice, A; Henry, K; Jackson, B; Ussery, FM1
Carter, WA; Mitchell, WM; Montefiori, DC; Robinson, WE; Strayer, DR1
Allain, JP; Dubinsky, R; Fischl, MA; Klecker, RW; McAtee, N; McNeely, MC; Perno, CF; Thomas, RV; Wills, RJ; Yarchoan, R1
Cload, P; Coutinho, RA; de Gans, J; de Wolf, F; Fiddian, AP; Goudsmit, J; Lange, JM; Schellekens, PT; van der Noordaa, J1
Boucher, CA; Danner, SA; Goudsmit, J; Lange, JM; Reiss, P1
Delord, B; Faivre, R; Fleury, HJ; Morere, G1
Forster, S; Helbert, M; Jeffries, D; Kocsis, A; Peddle, B; Pinching, AJ; Robinson, D1
Steel, M1
de Gans, J; Portegies, P; Tiessens, G1
Balzarini, J; De Clercq, E; Pauwels, R; Schols, D; Vanlangendonck, F1
De Clercq, E1
Marx, JL1
Balzarini, J; de Clercq, E; Herdewijn, P; van Aerschot, A1
Weber, J1
Baba, M; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Vandeputte, M1
Chen, MS; Kinney-Thomas, E; Lin, TS; Prusoff, WH; Schinazi, RF1
Harada, S; Nakashima, H; Yamamoto, N1
Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N1
Barry, DW; Furman, PA1
Gallo, RC; Montagnier, L1
Kobayashi, N; Matsuda, A; Nakashima, H; Tochikura, T; Ueda, T; Yamamoto, N1
Kaneko, Y; Kobayashi, N; Nakashima, H; Tochikura, TS; Yamamoto, N1
Ikuta, K; Imai, H; Kato, S; Suehiro, S; Ueda, S; Yamamoto, N2
Despotes, JC; Emeson, EE; Falk, LA; Jackson, GG; Knigge, M; Mack, D; Paul, DA; Rubenis, M1
Cload, P; Danner, SA; de Gans, J; de Wolf, F; Derix, MM; Eeftinck Schattenkerk, JK; Goudsmit, J; Lange, JM; Ongerboer de Visser, BW1
Courouce, AM; Lefrere, JJ; Salmon, C1
Dickmeiss, E; Permin, H1
Ersbøll, J; Krebs, HJ; Mathiesen, L; Petersen, CS1
Glaser, V1
Langen, P; Lehmann, C; Matthes, E; Rosenthal, HA; Scholz, D1
Balzarini, J; De Clercq, E; Kinjo, J; Lesiak, K; Torrence, PF1
Gericke, D1
Birch, C; Gust, I; Lucas, CR; Tachedjian, G1
Carlisle, R; Schinazi, RF; Sommadossi, JP; Zhou, Z1
Allain, JP; Boone, GS; Chaisson, RE; Feigal, D; Leuther, MD; Nusinoff-Lehrman, S; Volberding, P1
Barnes, DM1
Allain, JP; Chaisson, RE; Leuther, M; Volberding, PA1
Blumberg, RS; Byington, R; Chou, TC; Hartshorn, KL; Hirsch, MS; Schooley, RT; Vogt, MW1
Baba, M; De Clercq, E; Ito, M; Nakashima, H; Pauwels, R; Shigeta, S; Yamamoto, N1
Jablon, L1
Cohen, OJ; Lyerly, HK; Weinhold, KJ1
Gallo, RC1
Elwell, LP; Ferone, R; Freeman, GA; Fyfe, JA; Hill, JA; Knick, VB; Ray, PH; Richards, CA; Rideout, JL; Singer, SC1

Reviews

73 review(s) available for zidovudine and HIV

ArticleYear
Polypharmacology in HIV inhibition: can a drug with simultaneous action against two relevant targets be an alternative to combination therapy?
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Therapy, Combination; HIV; Humans; Microbial Sensitivity Tests; Molecular Structure; Polypharmacology

2018
Prevention of the Vertical Transmission of HIV; A Recap of the Journey so Far.
    Viruses, 2023, 03-26, Volume: 15, Issue:4

    Topics: Anti-HIV Agents; Child; Child, Preschool; Female; HIV; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2023
Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus.
    The Cochrane database of systematic reviews, 2023, 06-12, Volume: 6

    Topics: Antiviral Agents; Coinfection; DNA, Viral; Emtricitabine; Female; Hepatitis B e Antigens; Hepatitis B virus; HIV; HIV Infections; HIV Seropositivity; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnant Women; Ritonavir; Tenofovir; Zidovudine

2023
Recent progress in prodrug design strategies based on generally applicable modifications.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Amides; Animals; Anti-HIV Agents; Benzyl Compounds; Biological Availability; Carboxylic Acids; Drug Design; Esterification; HIV; HIV Infections; Humans; Prodrugs; Solubility; Zidovudine

2017
Optimal versus suboptimal treatment for HIV-infected pregnant women and HIV-exposed infants in clinical research studies.
    Journal of acquired immune deficiency syndromes (1999), 2009, Aug-15, Volume: 51, Issue:5

    Topics: Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2009
Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine.
    Antiviral research, 2010, Volume: 85, Issue:1

    Topics: Anti-HIV Agents; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Nucleosides; Nucleotides; Zidovudine

2010
Antiretrovirals for HIV Exposure Prophylaxis.
    Current medicinal chemistry, 2012, Volume: 19, Issue:35

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012
STI and beyond: the prospects of boosting anti-HIV immune responses.
    Trends in immunology, 2002, Volume: 23, Issue:9

    Topics: Acute Disease; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chronic Disease; HIV; HIV Infections; Humans; Zidovudine

2002
Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs).
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:9

    Topics: Adenosine Triphosphate; DNA Primers; Drug Resistance, Multiple, Viral; Foscarnet; HIV; HIV Reverse Transcriptase; Humans; Point Mutation; Reverse Transcriptase Inhibitors; Thymidine; Zidovudine

2004
[Sulfated schizophyllan as a anti-HIV agent].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Animals; Antiviral Agents; Blood Coagulation; Carbohydrate Conformation; Cells, Cultured; Drug Synergism; Female; HIV; Humans; Lethal Dose 50; Mice; Molecular Weight; Reverse Transcriptase Inhibitors; Sizofiran; Structure-Activity Relationship; Zidovudine

1993
A risk-benefit assessment of zidovudine in the prevention of perinatal HIV transmission.
    Drug safety, 1995, Volume: 12, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Animals; Drug Resistance, Microbial; Female; Guidelines as Topic; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Randomized Controlled Trials as Topic; Risk Assessment; Zidovudine

1995
HIV drug resistance.
    Annual review of pharmacology and toxicology, 1993, Volume: 33

    Topics: Animals; Antiviral Agents; Drug Resistance, Microbial; HIV; Humans; Reverse Transcriptase Inhibitors; Zidovudine

1993
Resistance, drug failure, and disease progression.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:8

    Topics: Antiviral Agents; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nevirapine; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1994
[Antiretroviral therapy. Current status and perspectives].
    Der Internist, 1994, Volume: 35, Issue:10

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine

1994
[Therapy of HIV infection with nucleoside analogs].
    Zeitschrift fur Gastroenterologie, 1993, Volume: 31 Suppl 5

    Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nucleosides; Zalcitabine; Zidovudine

1993
Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Zidovudine

1993
Studies of zidovudine in combination with didanosine and zalcitabine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Volume: 10 Suppl 1

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Safety; Zalcitabine; Zidovudine

1995
ddC (zalcitabine).
    Advances in experimental medicine and biology, 1996, Volume: 394

    Topics: Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine

1996
Human immunodeficiency virus replication in the presence of antiretroviral drugs: analogies to antineoplastic drug resistance.
    Cancer treatment and research, 1996, Volume: 87

    Topics: Antineoplastic Agents; Antiviral Agents; Drug Resistance; HIV; Humans; Virus Replication; Zidovudine

1996
[Monitoring anti-retroviral treatment].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14 Suppl 1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Evaluation; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Phenotype; RNA, Viral; Viremia; Zidovudine

1996
Antiretroviral agents. Current usage.
    Dermatologic clinics, 1997, Volume: 15, Issue:2

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Forecasting; HIV; HIV Infections; Humans; Research; Zidovudine

1997
The surgeon's database for AIDS: a collective review.
    Journal of the American College of Surgeons, 1997, Volume: 184, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Databases, Factual; General Surgery; HIV; HIV Antibodies; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Infectious Disease Transmission, Professional-to-Patient; Seroepidemiologic Studies; Universal Precautions; Zidovudine

1997
Antiretroviral therapy in human immunodeficiency virus-infected individuals.
    Advances in internal medicine, 1998, Volume: 43

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Chemoprevention; Clinical Protocols; Decision Making; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Vertical; Patient Care Planning; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Viremia; Virus Replication; Zidovudine

1998
[Past, present and future of zidovudine, the first antiretroviral drug].
    Anales de medicina interna (Madrid, Spain : 1984), 1998, Volume: 15, Issue:3

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Zidovudine

1998
Resistance of HIV to antiretroviral agents. Basic concepts.
    Journal of biological regulators and homeostatic agents, 1998, Volume: 12, Issue:1-2 Suppl

    Topics: Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4-Positive T-Lymphocytes; Drug Resistance, Microbial; HIV; Humans; Reverse Transcriptase Inhibitors; Thymidine Kinase; Zidovudine

1998
Management of possible sexual, injecting-drug-use, or other nonoccupational exposure to HIV, including considerations related to antiretroviral therapy. Public Health Service statement. Centers for Disease Control and Prevention.
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports, 1998, Sep-25, Volume: 47, Issue:RR-17

    Topics: Animals; Anti-HIV Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Resistance, Microbial; Evaluation Studies as Topic; HIV; HIV Infections; Humans; Risk; Risk-Taking; Sexual Behavior; Substance Abuse, Intravenous; Zidovudine

1998
Zidovudine: a review of pharmacoeconomic and quality-of-life considerations for its use in patients with human immunodeficiency virus.
    PharmacoEconomics, 1993, Volume: 3, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Child, Preschool; Clinical Trials as Topic; Cost of Illness; Cost-Benefit Analysis; Drug Tolerance; Economics, Pharmaceutical; Evaluation Studies as Topic; Female; Formularies as Topic; Health Care Costs; HIV; HIV Infections; Humans; Infant, Newborn; Male; Models, Econometric; Occupational Exposure; Pregnancy; Quality of Life; Survival Rate; Zidovudine

1993
[Rational therapy of HIV infections].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Diagnosis, Differential; Granulocyte Colony-Stimulating Factor; HIV; HIV Infections; Humans; Immune Tolerance; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

1999
Recurrence of the acute HIV syndrome after interruption of antiretroviral therapy in a patient with chronic HIV infection: A case report.
    Annals of internal medicine, 2000, Sep-19, Volume: 133, Issue:6

    Topics: Acute Disease; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Chronic Disease; Disease Progression; Drug Therapy, Combination; Fever; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Recurrence; Reverse Transcriptase Inhibitors; RNA, Viral; Syndrome; Viral Load; Zidovudine

2000
HIV drug resistance and viral fitness.
    Advances in pharmacology (San Diego, Calif.), 2000, Volume: 49

    Topics: Drug Resistance; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

2000
Ethical issues in early detection of HIV infection to reduce vertical transmission.
    Journal of acquired immune deficiency syndromes (1999), 2000, Dec-15, Volume: 25 Suppl 2

    Topics: Breast Feeding; Ethics; Female; Health Policy; HIV; HIV Seropositivity; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Informed Consent; Mandatory Testing; Pregnancy; Prenatal Care; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

2000
A critical analysis of the pharmacology of AZT and its use in AIDS.
    Current medical research and opinion, 1999, Volume: 15 Suppl 1

    Topics: Anti-HIV Agents; HIV; HIV Core Protein p24; HIV Infections; Humans; In Vitro Techniques; Phosphorylation; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1999
Emergence of mutant HIV reverse transcriptase conferring resistance to AZT.
    Journal of enzyme inhibition, 1992, Volume: 6, Issue:1

    Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Drug Resistance, Microbial; Genotype; HeLa Cells; HIV; HIV Infections; Humans; Molecular Sequence Data; Mutation; Phenotype; RNA-Directed DNA Polymerase; Time Factors; Zidovudine

1992
Anti-human immunodeficiency virus therapeutics: now and the future.
    Seminars in liver disease, 1992, Volume: 12, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dideoxynucleosides; HIV; HIV-1; Humans; Trichosanthin; Zalcitabine; Zidovudine

1992
Reverse transcriptase of HIV as a target for anti-viral drugs.
    Biochemical Society transactions, 1992, Volume: 20, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dideoxynucleosides; Drug Design; HIV; Humans; Reverse Transcriptase Inhibitors; Zidovudine

1992
HIV drug resistance.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:6

    Topics: Amino Acid Sequence; Base Sequence; Dideoxynucleosides; DNA, Viral; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Molecular Sequence Data; Zidovudine

1992
Competition between zidovudine-sensitive and zidovudine-resistant strains of HIV.
    AIDS (London, England), 1992, Volume: 6, Issue:1

    Topics: CD4 Antigens; Drug Resistance, Microbial; HIV; HIV Infections; Host-Parasite Interactions; Humans; Models, Biological; Zidovudine

1992
[Antiretroviral treatments and their therapeutical trials].
    La Revue du praticien, 1992, Jan-15, Volume: 42, Issue:2

    Topics: Antiviral Agents; Clinical Trials as Topic; HIV; HIV Infections; Humans; Zidovudine

1992
Selection of zidovudine-resistant variants of human immunodeficiency virus by therapy.
    Current topics in microbiology and immunology, 1992, Volume: 176

    Topics: Drug Resistance, Microbial; HIV; HIV Infections; Humans; Mutation; Zidovudine

1992
[Treatments of human immunodeficiency virus infection. Current developments].
    Annales de medecine interne, 1991, Volume: 142, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine

1991
DNA polymerases versus HIV reverse transcriptase in AIDS therapy.
    Annals of the New York Academy of Sciences, 1990, Volume: 616

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; DNA-Directed DNA Polymerase; HIV; Humans; RNA-Directed DNA Polymerase; Sensitivity and Specificity; Virus Replication; Zidovudine

1990
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991
Anti-retroviral therapy of human immunodeficiency virus infection: current strategies and challenges for the future.
    Blood, 1991, Aug-15, Volume: 78, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Resistance; HIV; HIV Infections; Humans; Lymphoma, Non-Hodgkin; Retroviridae; Reverse Transcriptase Inhibitors; T-Lymphocytes, Helper-Inducer; Virus Replication; Zalcitabine; Zidovudine

1991
Factors contributing to the inhibition of HIV reverse transcriptase by chain-terminating nucleotides in vitro and in vivo.
    FEBS letters, 1991, Oct-07, Volume: 291, Issue:1

    Topics: HIV; Nucleotides; Reverse Transcriptase Inhibitors; Templates, Genetic; Zidovudine

1991
Derivation of new drugs for therapy of AIDS.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Design; HIV; HIV Envelope Protein gp120; HIV Protease Inhibitors; Humans; Reverse Transcriptase Inhibitors; Zidovudine

1991
Preclinical evaluation of human hematolymphoid function in the SCID-hu mouse.
    Immunological reviews, 1991, Volume: 124

    Topics: Acquired Immunodeficiency Syndrome; Animals; Bone Marrow Transplantation; Didanosine; Hematopoiesis; HIV; Humans; Liver Transplantation; Lymph Nodes; Mice; Mice, SCID; Models, Biological; Thymus Gland; Transplantation, Heterologous; Zidovudine

1991
Therapy of AIDS and AIDS-related tumors.
    Cancer chemotherapy and biological response modifiers, 1991, Volume: 12

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; HIV; Hodgkin Disease; Humans; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma, Kaposi; Zidovudine

1991
Antiviral therapy for human immunodeficiency virus infection in children.
    Pediatric clinics of North America, 1991, Volume: 38, Issue:1

    Topics: Antiviral Agents; Child; HIV; HIV Infections; Humans; Virus Replication; Zidovudine

1991
Early therapeutic intervention in HIV infection--stepping stones to success.
    Immunodeficiency reviews, 1991, Volume: 2, Issue:4

    Topics: Drug Administration Schedule; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Pneumonia, Pneumocystis; Survival Rate; Zidovudine

1991
AZT resistance in isolates of HIV.
    Immunodeficiency reviews, 1991, Volume: 2, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Zidovudine

1991
Pharmacologic studies of nucleosides active against the human immunodeficiency virus.
    Annals of the New York Academy of Sciences, 1990, Volume: 616

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Bone Marrow Diseases; HIV; Humans; Nucleosides; Zidovudine

1990
Treatment of human immunodeficiency virus-infected infants and young children with dideoxynucleosides.
    The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Child; Child, Preschool; Dideoxynucleosides; Drug Tolerance; HIV; HIV Infections; Humans; Infant; Zalcitabine; Zidovudine

1990
Susceptibility to nucleoside analogues of zidovudine-resistant isolates of human immunodeficiency virus.
    The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B

    Topics: Antiviral Agents; Deoxyribonucleosides; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Microbial Sensitivity Tests; Zidovudine

1990
Antiviral therapy against HIV infection.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:6 Pt 2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dideoxynucleosides; HIV; HIV Infections; Humans; Zidovudine

1990
Developmental therapeutics and the acquired immunodeficiency syndrome.
    Annals of internal medicine, 1987, Volume: 106, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Deoxyribonucleosides; HIV; Humans; Interferons; Interleukin-2; Opportunistic Infections; Pneumonia, Pneumocystis; Thymidine; Toxoplasmosis; Virus Replication; Zidovudine

1987
Targets for antiviral therapy of human immunodeficiency virus infection.
    The Journal of infection, 1989, Volume: 18 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dideoxynucleosides; Drug Therapy, Combination; Genes, Regulator; HIV; Humans; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine

1989
Clinical and basic advances in the antiretroviral therapy of human immunodeficiency virus infection.
    The American journal of medicine, 1989, Volume: 87, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Child; Dideoxynucleosides; Female; HIV; Humans; Pregnancy; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1989
State of antiretroviral therapy with zidovudine.
    AIDS (London, England), 1989, Volume: 3 Suppl 1

    Topics: Drug Interactions; HIV; HIV Infections; Humans; Opportunistic Infections; Zidovudine

1989
AIDS update.
    Postgraduate medicine, 1989, Volume: 85, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Viral Vaccines; Zidovudine

1989
Congenital AIDS: review of neurologic problems.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1989, Volume: 5, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Immune System; Infant, Newborn; Nervous System; Nervous System Diseases; Zidovudine

1989
Clinical pharmacokinetics of zidovudine. An overview of current data.
    Clinical pharmacokinetics, 1989, Volume: 17, Issue:1

    Topics: Drug Interactions; Female; Half-Life; HIV; Humans; Maternal-Fetal Exchange; Pregnancy; Protein Binding; Semen; Zidovudine

1989
Clinical pharmacology of 3'-azido-2',3'-dideoxythymidine (zidovudine) and related dideoxynucleosides.
    The New England journal of medicine, 1989, Sep-14, Volume: 321, Issue:11

    Topics: Dideoxynucleosides; HIV; Humans; Zidovudine

1989
Azidothymidine.
    Nouvelle revue francaise d'hematologie, 1989, Volume: 31, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anemia, Macrocytic; Clinical Trials as Topic; Drug Interactions; HIV; Humans; Neutropenia; Random Allocation; Zidovudine

1989
[Causal therapy possibilities in HIV infections].
    Dermatologische Monatschrift, 1989, Volume: 175, Issue:8

    Topics: Antiviral Agents; HIV; HIV Infections; Humans; Virus Replication; Zidovudine

1989
Zidovudine.
    Missouri medicine, 1989, Volume: 86, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Virus Replication; Zidovudine

1989
Progress in the development of antiviral therapy for HTLV-III-associated diseases.
    Important advances in oncology, 1987

    Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Ribavirin; Rifabutin; Rifamycins; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine

1987
Perspectives for the chemotherapy of AIDS.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Glycyrrhetinic Acid; Glycyrrhizic Acid; HIV; Humans; Polysaccharides; Suramin; Zidovudine

1988
Spectrum of antiviral activity and mechanism of action of zidovudine. An overview.
    The American journal of medicine, 1988, Aug-29, Volume: 85, Issue:2A

    Topics: Animals; Antiviral Agents; HIV; Humans; Retroviridae; Thymidine; Virus Replication; Zidovudine

1988
AIDS therapies.
    Scientific American, 1988, Volume: 259, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Design; HIV; Humans; Immunotherapy; Zidovudine

1988
AIDS in 1988.
    Scientific American, 1988, Volume: 259, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Animals; Disease Outbreaks; HIV; HIV-1; HIV-2; Humans; Simian Immunodeficiency Virus; Viral Vaccines; Zidovudine

1988
Treatment of human immunodeficiency virus infections.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; HIV; Humans; Ribavirin; Thymidine; Zidovudine

1987
Strategies for the future chemotherapy of human immunodeficiency virus (HIV).
    Haematology and blood transfusion, 1987, Volume: 31

    Topics: Acquired Immunodeficiency Syndrome; Drug Evaluation; HIV; Humans; Thymidine; Zidovudine

1987
Development of antiretroviral therapy for the acquired immunodeficiency syndrome and related disorders. A progress report.
    The New England journal of medicine, 1987, Feb-26, Volume: 316, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Structure-Activity Relationship; Thymidine; Zidovudine

1987

Trials

60 trial(s) available for zidovudine and HIV

ArticleYear
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
    Lancet (London, England), 2009, Dec-19, Volume: 374, Issue:9707

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine

2009
Interferon-alpha produces significant decreases in HIV load.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2010, Volume: 30, Issue:7

    Topics: Adult; CD4-Positive T-Lymphocytes; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; HIV; HIV Infections; Humans; Immunophenotyping; Interferon-alpha; Male; Survival Analysis; Viral Load; Zidovudine

2010
Efavirenz versus boosted atazanavir or zidovudine and abacavir in antiretroviral treatment-naive, HIV-infected subjects: week 48 data from the Altair study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Oct-01, Volume: 51, Issue:7

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Oligopeptides; Pyridines; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2010
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.
    The Journal of infectious diseases, 2010, Nov-15, Volume: 202, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; RNA, Viral; South Africa; Stavudine; Treatment Outcome; Zidovudine

2010
A comparison of 3 regimens to prevent nevirapine resistance mutations in HIV-infected pregnant women receiving a single intrapartum dose of nevirapine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Jan-15, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Middle Aged; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Viral Load; Zidovudine

2012
Pharmacokinetics and safety of a new paediatric fixed-dose combination of zidovudine/lamivudine/nevirapine in HIV-infected children.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Anti-HIV Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biological Availability; Body Weight; Child; Child, Preschool; Cytochrome P-450 CYP2B6; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Oxidoreductases, N-Demethylating; Reverse Transcriptase Inhibitors; Tablets; Zidovudine

2011
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
    Journal of acquired immune deficiency syndromes (1999), 2002, Dec-15, Volume: 31, Issue:5

    Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mutation; Patient Compliance; RNA, Viral; Stavudine; Viral Load; Zidovudine

2002
Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Jan-15, Volume: 38, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Female; HIV; HIV Infections; HIV-1; Humans; Lipodystrophy; Male; Middle Aged; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2004
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV.
    The New England journal of medicine, 2006, Jan-19, Volume: 354, Issue:3

    Topics: Adenine; Adolescent; Adult; Aged; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Oxazines; Prospective Studies; RNA, Viral; Tenofovir; Zidovudine

2006
Postexposure prophylaxis for HIV in children and adolescents after sexual assault: a prospective observational study in an urban medical center.
    Sexually transmitted diseases, 2007, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Anti-HIV Agents; Child; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; New York City; Patient Compliance; Prospective Studies; Regression Analysis; Sex Offenses; Zidovudine

2007
Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program.
    Journal of acquired immune deficiency syndromes (1999), 2007, Mar-01, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV; HIV Infections; Humans; Lamivudine; Milk, Human; Nevirapine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; RNA, Viral; Stavudine; Zidovudine

2007
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.
    Journal of acquired immune deficiency syndromes (1999), 2007, Aug-15, Volume: 45, Issue:5

    Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Composition; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Time Factors; Treatment Outcome; United States; Zidovudine

2007
A comparison of three initial antiretroviral AIDS regimens.
    The New England journal of medicine, 2007, Sep-06, Volume: 357, Issue:10

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; HIV; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

2007
Fixed duration interruptions are inferior to continuous treatment in African adults starting therapy with CD4 cell counts < 200 cells/microl.
    AIDS (London, England), 2008, Jan-11, Volume: 22, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Candidiasis; CD4 Lymphocyte Count; Disease Progression; Drug Administration Schedule; Esophageal Diseases; Female; HIV; Humans; Male; Middle Aged; Treatment Outcome; Uganda; Zidovudine; Zimbabwe

2008
Early features of zidovudine-associated myopathy: histopathological findings and clinical correlations.
    Acta neuropathologica, 1995, Volume: 90, Issue:1

    Topics: Adult; Biopsy; Electromyography; Electrophysiology; HIV; Humans; Middle Aged; Muscle Fatigue; Muscular Diseases; Zidovudine

1995
Resistance, drug failure, and disease progression.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:8

    Topics: Antiviral Agents; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nevirapine; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1994
Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Mar-01, Volume: 8, Issue:3

    Topics: Adult; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV; HIV Core Protein p24; HIV Infections; Humans; Injections, Subcutaneous; Male; Middle Aged; Patient Compliance; Pentamidine; Pneumonia, Pneumocystis; Prognosis; Proportional Hazards Models; Thymopentin; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

1995
Resistance to AZT and ddC during long-term combination therapy in patients with advanced infection with human immunodeficiency virus.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:2

    Topics: CD4-Positive T-Lymphocytes; Drug Resistance, Microbial; Drug Therapy, Combination; HeLa Cells; HIV; HIV Infections; Humans; Leukocyte Count; Time Factors; Zalcitabine; Zidovudine

1994
Improved cell-mediated immune responses in HIV-1-infected asymptomatic individuals after immunization with envelope glycoprotein gp160.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:3

    Topics: Adult; CD4-Positive T-Lymphocytes; Female; Follow-Up Studies; Gene Products, env; HIV; HIV Core Protein p24; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV Seropositivity; Humans; Immunity, Cellular; Immunization; Immunization, Secondary; Leukocyte Count; Lymphocyte Activation; Male; Middle Aged; Peptide Fragments; Protein Precursors; Recombinant Proteins; Zidovudine

1994
Combination treatment with zidovudine, thymosin alpha 1 and interferon-alpha in human immunodeficiency virus infection.
    International journal of clinical & laboratory research, 1994, Volume: 24, Issue:1

    Topics: Adult; CD4-Positive T-Lymphocytes; Combined Modality Therapy; Cytotoxicity, Immunologic; Drug Synergism; Female; HIV; HIV Infections; Humans; Immunologic Factors; Interferon-alpha; Leukocyte Count; Male; Risk Factors; Thymalfasin; Thymosin; Virus Replication; Zidovudine

1994
Zidovudine resistance, syncytium-inducing phenotype, and HIV disease progression in a case-control study. The VA Cooperative Study Group.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; Case-Control Studies; Drug Resistance, Microbial; Follow-Up Studies; Giant Cells; HIV; HIV Infections; Humans; Middle Aged; Phenotype; Retrospective Studies; Zidovudine

1993
Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine. AIDS Clinical Trials Group.
    The New England journal of medicine, 1996, Apr-18, Volume: 334, Issue:16

    Topics: Adult; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Male; Quinolines; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Treatment Outcome; Zalcitabine; Zidovudine

1996
Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:4

    Topics: Adult; Antiviral Agents; Base Sequence; Biomarkers; CD4 Lymphocyte Count; DNA Primers; Female; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; In Situ Hybridization; Lymph Nodes; Male; Molecular Sequence Data; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Time Factors; Virus Replication; Zidovudine

1996
Lamivudine plus zidovudine compared with zalcitabine plus zidovudine in patients with HIV infection. A randomized, double-blind, placebo-controlled trial. North American HIV Working Party.
    Annals of internal medicine, 1996, Aug-01, Volume: 125, Issue:3

    Topics: Adult; Antiviral Agents; beta 2-Microglobulin; Biopterins; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Core Protein p24; HIV Infections; Humans; Lamivudine; Male; Neopterin; Polymerase Chain Reaction; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Outcome; Zalcitabine; Zidovudine

1996
The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team.
    The New England journal of medicine, 1996, Oct-10, Volume: 335, Issue:15

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Multivariate Analysis; Phenotype; Proportional Hazards Models; RNA, Viral; Treatment Outcome; Virus Replication; Zidovudine

1996
Interleukin-2 in combination with zidovudine and didanosine is able to maintain high levels of CD4 cells and undetectable HIV viraemia.
    AIDS (London, England), 1998, Jan-01, Volume: 12, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Interleukin-2; Leukocyte Common Antigens; Male; Pilot Projects; RNA, Viral; Viremia; Zidovudine

1998
Pilot study of zidovudine-lamivudine combination therapy in vertically HIV-infected antiretroviral-naive children.
    AIDS (London, England), 1998, Mar-26, Volume: 12, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pilot Projects; RNA, Viral; Viral Load; Zidovudine

1998
[Prophylaxis after occupational exposure to human immunodeficiency virus (HIV)].
    Polskie Archiwum Medycyny Wewnetrznej, 1997, Volume: 98, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Female; Health Knowledge, Attitudes, Practice; Health Personnel; HIV; HIV Seropositivity; Humans; Male; Middle Aged; Needlestick Injuries; Occupational Diseases; Occupational Exposure; Risk Assessment; Zidovudine

1997
A phase I/II study of the protease inhibitor indinavir in children with HIV infection.
    Pediatrics, 1998, Volume: 102, Issue:1 Pt 1

    Topics: Adolescent; Adult; Biological Availability; Capsules; CD4 Lymphocyte Count; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infant; Lamivudine; Male; Suspensions; Viral Load; Virus Replication; Zidovudine

1998
Correlation of response to treatment and HIV genotypic changes during phase III trials with saquinavir and reverse transcriptase inhibitor combination therapy.
    AIDS (London, England), 1998, Aug-20, Volume: 12, Issue:12

    Topics: Amino Acid Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Phenotype; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Treatment Outcome; Zalcitabine; Zidovudine

1998
An open randomized controlled trial of zidovudine plus lamivudine versus stavudine plus lamivudine.
    AIDS (London, England), 1998, Aug-20, Volume: 12, Issue:12

    Topics: Adult; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Homosexuality, Male; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1998
A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. AIDS Clinical Trial Group 193A Study T
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Dec-01, Volume: 19, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV; Humans; Male; Nevirapine; Placebos; Reverse Transcriptase Inhibitors; RNA, Viral; Survival Rate; Time Factors; Zalcitabine; Zidovudine

1998
Intermittent selection pressure with zidovudine plus zalcitabine treatment reduces the emergence in vivo of zidovudine resistance HIV mutations.
    Journal of medical virology, 1999, Volume: 57, Issue:2

    Topics: Adult; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count; DNA Mutational Analysis; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Male; Mutation; RNA, Viral; Zalcitabine; Zidovudine

1999
Therapeutic vaccination with p24-VLP and zidovudine augments HIV-specific cytotoxic T lymphocyte activity in asymptomatic HIV-infected individuals.
    AIDS research and human retroviruses, 1999, Jan-20, Volume: 15, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Vaccines; Anti-HIV Agents; CD4-CD8 Ratio; Cohort Studies; Female; HIV; HIV Core Protein p24; Humans; Male; Middle Aged; Polymerase Chain Reaction; RNA, Viral; T-Lymphocytes, Cytotoxic; Viral Load; Zidovudine

1999
Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Trilège (Agence Nationale de Recherches sur le SIDA 072) Study Team).
    JAMA, 2000, Jan-12, Volume: 283, Issue:2

    Topics: Anti-HIV Agents; Case-Control Studies; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Patient Compliance; Treatment Failure; Viral Load; Zidovudine

2000
3-year suppression of HIV viremia with indinavir, zidovudine, and lamivudine.
    Annals of internal medicine, 2000, Jul-04, Volume: 133, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Genotype; HIV; HIV Infections; Humans; Indinavir; Kidney Calculi; Lamivudine; Male; Middle Aged; RNA, Viral; Viral Load; Viremia; Zidovudine

2000
Disease progression and early viral dynamics in human immunodeficiency virus-infected children exposed to zidovudine during prenatal and perinatal periods.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:1

    Topics: Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Disease Progression; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Multivariate Analysis; Outcome Assessment, Health Care; Perinatal Care; Prenatal Care; RNA, Viral; Zidovudine

2000
In vivo antagonism with zidovudine plus stavudine combination therapy.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Zidovudine

2000
Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.
    AIDS (London, England), 2000, Sep-29, Volume: 14, Issue:14

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine

2000
Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial.
    JAMA, 2001, Mar-07, Volume: 285, Issue:9

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Resistance, Microbial; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Indinavir; Lamivudine; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Survival Analysis; Therapeutic Equivalency; Viral Load; Zidovudine

2001
Long-term virologic and immunologic responses in human immunodeficiency virus type 1-infected children treated with indinavir, zidovudine, and lamivudine.
    The Journal of infectious diseases, 2001, Apr-01, Volume: 183, Issue:7

    Topics: Adolescent; Anti-HIV Agents; CD4 Antigens; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Leukocyte Common Antigens; Male; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RNA, Viral; Viral Load; Zidovudine

2001
Combination shows reduction in viral levels.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; HIV Seropositivity; Humans; Indinavir; Lamivudine; Time Factors; Zidovudine

1996
Drug combination shows benefits for AIDS patients with history of taking AZT.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; HIV; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Zidovudine

1996
Phase II/III Trials of Viracept start.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:3

    Topics: Anti-HIV Agents; Blood; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; Stavudine; Sulfonic Acids; Time Factors; Zidovudine

1996
Reappraising d4T.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:6

    Topics: CD4 Lymphocyte Count; HIV; HIV Infections; Humans; Randomized Controlled Trials as Topic; Stavudine; Zidovudine

1995
Major study shows AZT monotherapy inferior.
    AIDS treatment news, 1995, Sep-29, Issue:no 231

    Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1995
[Antiretroviral treatments and their therapeutical trials].
    La Revue du praticien, 1992, Jan-15, Volume: 42, Issue:2

    Topics: Antiviral Agents; Clinical Trials as Topic; HIV; HIV Infections; Humans; Zidovudine

1992
Peripheral nerve function in persons with asymptomatic or minimally symptomatic HIV disease: absence of zidovudine neurotoxicity.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; HIV; Humans; Male; Neurons, Afferent; Peripheral Nervous System Diseases; Placebos; Zidovudine

1991
Augmentation of cellular immune function during the early phase of zidovudine treatment of AIDS patients.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4-Positive T-Lymphocytes; Cohort Studies; Cytomegalovirus; Female; Follow-Up Studies; Gene Products, gag; HIV; HIV Antigens; HIV Core Protein p24; Humans; Immunity, Cellular; Interferon-gamma; Killer Cells, Natural; Leukocyte Count; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Simplexvirus; T-Lymphocytes; Viral Core Proteins; Zidovudine

1991
Mismatched double-stranded RNA, Ampligen (poly(I): poly(C12U), demonstrates antiviral and immunostimulatory activities in HIV disease.
    International journal of immunopharmacology, 1991, Volume: 13 Suppl 1

    Topics: Adjuvants, Immunologic; Antiviral Agents; CD4-Positive T-Lymphocytes; HIV; HIV Infections; Humans; Leukocyte Count; Poly I-C; Poly U; RNA, Double-Stranded; Zidovudine

1991
Drug level monitoring in a double-blind multicenter trial: false-positive zidovudine measurements in AIDS clinical trials group protocol 019.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Chromatography, High Pressure Liquid; False Positive Reactions; Fluorescence Polarization Immunoassay; Fluorescent Antibody Technique; HIV; Hot Temperature; Humans; Quality Control; Radioimmunoassay; Spectrophotometry, Ultraviolet; Zidovudine

1991
Dideoxycytidine (ddC): a potent antiretroviral agent for human immunodeficiency virus infection. An introduction.
    The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine

1990
[Chemotherapy and immunoprophylaxis of HIV infection].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1986, Nov-25, Volume: 75, Issue:48

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Ribavirin; Suramin; Thymidine; Viral Vaccines; Virus Replication; Zidovudine

1986
The use of zidovudine.
    International journal of dermatology, 1989, Volume: 28, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; HIV; Humans; Zidovudine

1989
Azidothymidine.
    Nouvelle revue francaise d'hematologie, 1989, Volume: 31, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anemia, Macrocytic; Clinical Trials as Topic; Drug Interactions; HIV; Humans; Neutropenia; Random Allocation; Zidovudine

1989
Zidovudine in patients with human immunodeficiency virus (HIV) infection and Kaposi sarcoma. A phase II randomized, placebo-controlled trial.
    Annals of internal medicine, 1989, Jul-01, Volume: 111, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anemia; Double-Blind Method; Drug Evaluation; Granulocytes; HIV; Humans; Leukocyte Count; Male; Middle Aged; Prospective Studies; Random Allocation; Sarcoma, Kaposi; Zidovudine

1989
Effect of zidovudine on serum human immunodeficiency virus antigen levels in symptom-free subjects.
    Lancet (London, England), 1988, Feb-20, Volume: 1, Issue:8582

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antigens, Viral; Antiviral Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; HIV; Homosexuality; Humans; Male; Random Allocation; Thymidine; Zidovudine

1988
Human immunodeficiency virus (HIV) antigenemia (p24) in the acquired immunodeficiency syndrome (AIDS) and the effect of treatment with zidovudine (AZT).
    Annals of internal medicine, 1988, Volume: 108, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antigens, Viral; Antiviral Agents; Clinical Trials as Topic; Double-Blind Method; HIV; HIV Antigens; HIV Core Protein p24; Humans; Lymphocytes; Retroviridae Proteins; Thymidine; Zidovudine

1988
Effect of zidovudine on serum human immunodeficiency virus core antigen levels. Results from a placebo-controlled trial.
    Archives of internal medicine, 1988, Volume: 148, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Double-Blind Method; Drug Evaluation; HIV; HIV Antigens; Humans; Leukocyte Count; Random Allocation; T-Lymphocytes; Zidovudine

1988
"On the shelf" AIDS drug in clinical trial.
    Science (New York, N.Y.), 1987, Oct-16, Volume: 238, Issue:4825

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Fusidic Acid; HIV; Humans; Thymidine; Virus Replication; Zidovudine

1987

Other Studies

464 other study(ies) available for zidovudine and HIV

ArticleYear
3',3'-Difluoro-3'-deoxythymidine: comparison of anti-HIV activity to 3'-fluoro-3'-deoxythymidine.
    Journal of medicinal chemistry, 1992, Sep-04, Volume: 35, Issue:18

    Topics: Antiviral Agents; Dideoxynucleosides; HIV; Molecular Conformation; Structure-Activity Relationship

1992
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides.
    Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8

    Topics: Antiviral Agents; Cell Line; HIV; Nucleosides; Structure-Activity Relationship

1992
Synthesis and anti-HIV activity of 4'-thio-2',3'-dideoxynucleosides.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Antiviral Agents; Dideoxynucleosides; HIV

1992
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin- 2(1H)-one (TIBO) derivatives.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Antiviral Agents; Benzodiazepinones; Chemical Phenomena; Chemistry; HIV; Structure-Activity Relationship; Virus Replication

1991
Escherichia coli mediated biosynthesis and in vitro anti-HIV activity of lipophilic 6-halo-2',3'-dideoxypurine nucleosides.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Adenosine Deaminase; Cells, Cultured; Chemical Phenomena; Chemistry; Dideoxynucleosides; Escherichia coli; HIV; Kinetics; Prodrugs; Structure-Activity Relationship

1991
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Kinetics; Prodrugs; Structure-Activity Relationship

1991
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine

1990
Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Survival; Chemical Phenomena; Chemistry; Fluorine; Gene Products, gag; HIV; HIV Antigens; HIV Core Protein p24; Humans; Macrophages; Molecular Structure; Monocytes; Pyrimidine Nucleosides; T-Lymphocytes; Tumor Cells, Cultured; Viral Core Proteins; Zalcitabine; Zidovudine

1990
Synthesis and antiviral activity of some acyclic and C-acyclic pyrrolo[2,3-d]pyrimidine nucleoside analogues.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Antiviral Agents; Chemical Phenomena; Chemistry; HIV; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrimidine Nucleosides; Pyrroles; Simplexvirus

1990
Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Dideoxyadenosine; Dideoxynucleosides; HIV; Leukemia P388; Molecular Structure; Purine Nucleosides; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication; Zidovudine

1990
Synthesis, antiretrovirus effects, and phosphorylation kinetics of 3'-isocyano-3'-deoxythymidine and 3'-isocyano-2',3'-dideoxyuridine.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:2

    Topics: Antimetabolites; Antiviral Agents; Cell Survival; Chemical Phenomena; Chemistry; Dideoxynucleosides; HIV; Kinetics; Phosphorylation; Thymidine; Thymidine Kinase; Virus Replication

1990
Cyclobut-A and cyclobut-G: broad-spectrum antiviral agents with potential utility for the therapy of AIDS.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Antiviral Agents; Guanine; Herpesviridae; HIV; Humans; Mice; Microbial Sensitivity Tests

1990
Synthesis and biological evaluation of prodrugs of zidovudine.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:5

    Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; HIV; Humans; Microsomes, Liver; Prodrugs; Rats; Structure-Activity Relationship; Virus Replication; Zidovudine

1990
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction

1990
Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Animals; Antiviral Agents; Brain; Chemical Phenomena; Chemistry; Dihydropyridines; Half-Life; HIV; Humans; Mice; Molecular Structure; Prodrugs; Zidovudine

1990
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: Antiviral Agents; Bone Marrow; Dideoxynucleosides; HIV; Stavudine; Thymidine; Zidovudine

1989
Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; HIV; Magnetic Resonance Spectroscopy; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Virus Replication; Zidovudine

1988
Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV).
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:2

    Topics: Antiviral Agents; HIV; Humans; Pyrimidine Nucleosides; Structure-Activity Relationship

1988
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication

1987
Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; HIV; Structure-Activity Relationship

1987
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship

1987
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(phosphonomethoxy) propyl]guanines.
    Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20

    Topics: Antiviral Agents; Aza Compounds; Cell Line; Guanine; HIV; Humans; Stereoisomerism

1995
Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin.
    Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20

    Topics: Antibiotics, Antineoplastic; Antiviral Agents; Arabinonucleosides; Cytomegalovirus; Herpesvirus 1, Human; HIV; Humans; KB Cells; Pyrimidine Nucleosides; Toyocamycin

1995
5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9

    Topics: Animals; Antiviral Agents; Base Sequence; Biological Availability; HIV; HIV Reverse Transcriptase; HIV-1; Indoles; Macaca mulatta; Molecular Sequence Data; Molecular Structure; Reverse Transcriptase Inhibitors; Sulfoxides

1993
Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (+/-)-calanolide A and its enantiomers.
    Journal of medicinal chemistry, 1996, Mar-15, Volume: 39, Issue:6

    Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Coumarins; HIV; HIV Reverse Transcriptase; Nucleic Acid Synthesis Inhibitors; Pyranocoumarins; RNA-Directed DNA Polymerase; Stereoisomerism

1996
Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones.
    Journal of medicinal chemistry, 1996, May-10, Volume: 39, Issue:10

    Topics: Antineoplastic Agents; Antiviral Agents; Cell Line; Chromans; HIV; Humans; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Tumor Cells, Cultured

1996
Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.
    Journal of medicinal chemistry, 1996, Apr-12, Volume: 39, Issue:8

    Topics: 3T3 Cells; Animals; Antiviral Agents; HIV; Mice; Phosphates; Stavudine; Structure-Activity Relationship

1996
Bioactive kaurane diterpenoids from Annona glabra.
    Journal of natural products, 1998, Volume: 61, Issue:4

    Topics: Anti-HIV Agents; Carbohydrate Sequence; Diterpenes; HIV; Humans; Lymphocytes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Plants, Medicinal; Reverse Transcriptase Inhibitors; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet

1998
Rational design of a new series of pronucleotide.
    Bioorganic & medicinal chemistry letters, 2001, Jul-09, Volume: 11, Issue:13

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Design; HIV; Nucleotides; Prodrugs; Virus Replication

2001
Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp.
    Journal of natural products, 2001, Volume: 64, Issue:11

    Topics: Animals; Antimalarials; Bromobenzenes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dioxanes; Gas Chromatography-Mass Spectrometry; Hepatitis B; HIV; Humans; Jamaica; Lactones; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Mycobacterium tuberculosis; Neoplasms, Unknown Primary; Nuclear Magnetic Resonance, Biomolecular; Plasmodium berghei; Plasmodium falciparum; Porifera; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured

2001
Synthesis and antiviral activity of C-fluoro-branched cyclopropyl nucleosides.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:4

    Topics: Antiviral Agents; Cells, Cultured; Cyclopropanes; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV; Humans; Hydrocarbons, Fluorinated; Microbial Sensitivity Tests; Molecular Structure; Nucleosides

2007
Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Anti-HIV Agents; Cell Line; Dideoxynucleotides; Dose-Response Relationship, Drug; HeLa Cells; HIV; Humans; Phosphorylation; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Virus Replication; Zidovudine

2007
Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Anti-HIV Agents; Caco-2 Cells; Cell Line, Tumor; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; HIV; HIV Integrase Inhibitors; Humans; Indoles; Integrases; Molecular Structure; Polymerase Chain Reaction; Viral Proteins; Virus Replication

2008
Studies on anti-HIV quinolones: new insights on the C-6 position.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-HIV Agents; HIV; Humans; Quinolones; Structure-Activity Relationship; Transcription, Genetic; Virus Replication

2009
Synthesis and antiviral evaluation of thieno[3,4-d]pyrimidine C-nucleoside analogues of 2',3'-dideoxy- and 2',3'-dideoxy-2',3'-didehydro-adenosine and -inosine.
    Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6

    Topics: Adenosine; Antiviral Agents; HIV; Inosine; Magnetic Resonance Spectroscopy; Pyrimidines; Spectrometry, Mass, Electrospray Ionization

2009
Aryl nucleoside H-phosphonates. Part 16: synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters.
    Bioorganic & medicinal chemistry, 2009, May-01, Volume: 17, Issue:9

    Topics: Anti-HIV Agents; Cell Line; Cells, Cultured; HIV; Humans; Hydroxy Acids; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Nucleotides; Organophosphonates; Virus Replication

2009
"Viologen" dendrimers as antiviral agents: the effect of charge number and distance.
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Anti-HIV Agents; Antiviral Agents; Cell Line; Dendrimers; HIV; Humans; Static Electricity; Structure-Activity Relationship; Viologens

2010
Synthesis and evaluation of beta-carboline derivatives as inhibitors of human immunodeficiency virus.
    Bioorganic & medicinal chemistry letters, 2010, Aug-01, Volume: 20, Issue:15

    Topics: Anti-HIV Agents; Carbolines; Cell Line; Formates; HIV; Humans

2010
Anti-HIV and antiplasmodial activity of original flavonoid derivatives.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Anti-HIV Agents; Antimalarials; Cell Line; Cell Survival; Flavonoids; HIV; HIV Infections; Humans; Malaria, Falciparum; Plasmodium falciparum

2010
Compounds from Kadsura angustifolia with anti-HIV activity.
    Bioorganic & medicinal chemistry letters, 2011, Feb-01, Volume: 21, Issue:3

    Topics: Anti-HIV Agents; Cell Line, Tumor; HIV; Humans; Kadsura; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Stems; Triterpenes

2011
Asymmetric total synthesis of (+)- and (-)-clusianone and (+)- and (-)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity.
    Bioorganic & medicinal chemistry letters, 2011, Apr-15, Volume: 21, Issue:8

    Topics: Alkylation; Anti-HIV Agents; Benzophenones; Benzoquinones; Bridged Bicyclo Compounds; Cell Line; Ethers; HIV; Humans; Stereoisomerism

2011
Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins.
    Bioorganic & medicinal chemistry, 2012, Feb-15, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Anti-HIV Agents; Cell Membrane Permeability; Cell-Penetrating Peptides; Circular Dichroism; HeLa Cells; HIV; Humans; Models, Molecular; Molecular Sequence Data; Peptide Library

2012
Design, synthesis and antiviral activity of novel quinazolinones.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Antiviral Agents; Chemistry Techniques, Synthetic; Drug Design; HIV; Quinazolinones; Tobacco Mosaic Virus

2012
Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus.
    Journal of medicinal chemistry, 2013, Nov-14, Volume: 56, Issue:21

    Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; HIV; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Structure-Activity Relationship; Zidovudine

2013
Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification.
    Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23

    Topics: Antiviral Agents; Cell Line, Tumor; DNA, Viral; Dose-Response Relationship, Drug; Guanine; HEK293 Cells; Herpesvirus 2, Human; HIV; Humans; Leukocytes, Mononuclear; Molecular Structure; Nucleic Acid Amplification Techniques; Organophosphonates; Papillomaviridae; Structure-Activity Relationship; Virus Replication

2016
Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities.
    European journal of medicinal chemistry, 2020, Jan-15, Volume: 186

    Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV; HIV Reverse Transcriptase; Humans; Indazoles; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2020
Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment.
    Bioorganic & medicinal chemistry, 2020, 06-01, Volume: 28, Issue:11

    Topics: Anti-HIV Agents; Capsid Proteins; Dose-Response Relationship, Drug; HIV; Humans; Microbial Sensitivity Tests; Molecular Structure; Peptide Fragments; Structure-Activity Relationship

2020
Design, synthesis and anti-HIV evaluation of novel 5-substituted diarylpyrimidine derivatives as potent HIV-1 NNRTIs.
    Bioorganic & medicinal chemistry, 2021, 06-15, Volume: 40

    Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; HIV; HIV Reverse Transcriptase; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2021
Tigliane-Type Diterpene Esters from the Fruits of
    Journal of natural products, 2022, 11-25, Volume: 85, Issue:11

    Topics: Anti-HIV Agents; Cell Line; Euphorbiaceae; Fruit; HIV; Humans; Molecular Structure; Phorbol Esters

2022
Rapid simultaneous analysis of anti human immunodeficiency virus drugs in pharmaceutical formulation by smart spectrophotometry based on multivariate calibration and least squares support vector machine methods.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2023, Apr-05, Volume: 290

    Topics: Calibration; Drug Compounding; HIV; Lamivudine; Least-Squares Analysis; Spectrophotometry; Support Vector Machine; Zidovudine

2023
Cryptococcal meningitis and immune reconstitution inflammatory syndrome in a pediatric patient with HIV after switching to second line antiretroviral therapy: a case report.
    BMC infectious diseases, 2020, Jan-21, Volume: 20, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antifungal Agents; Antigens, Fungal; Benzoxazines; Child; Cryptococcus neoformans; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Female; Fluconazole; HIV; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Lopinavir; Meningitis, Cryptococcal; Ritonavir; Treatment Outcome; Viral Load; Zidovudine

2020
High rates of tenofovir failure in a CRF01_AE-predominant HIV epidemic in the Philippines.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 95

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Epidemics; Female; HIV; HIV Infections; Humans; Male; Philippines; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2020
Case report: one case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a normal CD4
    AIDS research and therapy, 2020, 07-23, Volume: 17, Issue:1

    Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Betacoronavirus; C-Reactive Protein; CD4 Lymphocyte Count; Chills; Coronavirus Infections; COVID-19; Cyclopropanes; Fatigue; Female; Fever; HIV; HIV Infections; Humans; Immunocompromised Host; Immunoglobulin M; Lamivudine; Middle Aged; Pandemics; Pharyngitis; Pneumonia, Viral; Real-Time Polymerase Chain Reaction; SARS-CoV-2; Sputum; Time Factors; Tomography, X-Ray Computed; Virus Shedding; Zidovudine

2020
Prevalence and evaluation of risk factors of anti-retroviral therapy failure among human immunodeficiency virus/acquired immune deficiency syndrome patients in North India.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2021, 09-03, Volume: 115, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; HIV; HIV Infections; Humans; India; Lamivudine; Male; Prevalence; Risk Factors; Viral Load; Zidovudine

2021
Encapsulation of zidovudine in PF-68 coated alginate conjugate nanoparticles for anti-HIV drug delivery.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt A

    Topics: Alginates; Amides; Anti-HIV Agents; Chitosan; Drug Carriers; Drug Delivery Systems; Glucuronic Acid; Hexuronic Acids; HIV; HIV Infections; Humans; Nanoparticles; Zidovudine

2018
HBV, HCV, and HBV/HCV co-infection among HIV-positive patients in Hunan province, China: Regimen selection, hepatotoxicity, and antiretroviral therapy outcome.
    Journal of medical virology, 2018, Volume: 90, Issue:3

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cohort Studies; Coinfection; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Retrospective Studies; Treatment Outcome; Viral Load; Zidovudine

2018
Impact of Timing of Antiretroviral Treatment and Birth Weight on Mother-to-Child Human Immunodeficiency Virus Transmission: Findings From an 18-Month Prospective Cohort of a Nationally Representative Sample of Mother-Infant Pairs During the Transition Fro
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 02-01, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Birth Weight; Breast Feeding; Female; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Time Factors; Zidovudine; Zimbabwe

2018
Adherence, virological outcome, and drug resistance in Chinese HIV patients receiving first-line antiretroviral therapy from 2011 to 2015.
    Medicine, 2018, Volume: 97, Issue:50

    Topics: Adult; Anti-HIV Agents; China; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Retrospective Studies; Stavudine; Sustained Virologic Response; Tenofovir; Zidovudine

2018
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
    Lipids in health and disease, 2013, Apr-10, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine

2013
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine

2013
Clinical manifestations and treatment outcomes in HIV-1-infected children receiving antiretroviral therapy in Karachi, Pakistan.
    Journal of infection in developing countries, 2014, Apr-15, Volume: 8, Issue:4

    Topics: Anti-HIV Agents; Body Height; Body Weight; CD4 Lymphocyte Count; Child, Preschool; Drug Resistance, Viral; Female; Genotype; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Pakistan; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine

2014
MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Drug Resistance, Viral; Female; Gene Expression Regulation; HIV; Humans; Lamivudine; Leukocytes, Mononuclear; Male; MicroRNAs; Nevirapine; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2014
[HIV encephalopathy due to drug resistance despite 2-year suppression of HIV viremia by cART].
    Rinsho shinkeigaku = Clinical neurology, 2014, Volume: 54, Issue:9

    Topics: AIDS Dementia Complex; Anti-Retroviral Agents; Central Nervous System; Cognition Disorders; Darunavir; Disease Progression; Drug Resistance, Viral; Drug Substitution; HIV; HIV Infections; Humans; Male; Middle Aged; Pyrrolidinones; Raltegravir Potassium; Ritonavir; RNA, Viral; Sulfonamides; Time Factors; Viremia; Zidovudine

2014
Is zidovudine first-line therapy virologically comparable to tenofovir in resource-limited settings?
    Tropical medicine & international health : TM & IH, 2015, Volume: 20, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; Health Resources; HIV; HIV Infections; Humans; Lamivudine; Lesotho; Logistic Models; Male; Middle Aged; Organophosphonates; Tenofovir; Viral Load; Zidovudine

2015
Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-infected Patients Treated with Highly Active Antiretroviral Therapy (HAART).
    Current molecular medicine, 2015, Volume: 15, Issue:10

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; Case-Control Studies; Cyclopropanes; DNA, Mitochondrial; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Lopinavir; Male; Middle Aged; Mitochondria; Nelfinavir; Predictive Value of Tests; Ritonavir; ROC Curve; Stavudine; Zidovudine

2015
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia.
    Antiviral therapy, 2017, Volume: 22, Issue:2

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Coinfection; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Ethiopia; Female; Genetic Variation; Genome, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Immune Evasion; Lamivudine; Male; Mutation; Stavudine; Viral Load; Zidovudine

2017
Early infant diagnosis of HIV infection using DNA-PCR at a referral center: an 8 years retrospective analysis.
    AIDS research and therapy, 2016, Volume: 13, Issue:1

    Topics: Anti-HIV Agents; DNA, Viral; Early Diagnosis; Ethiopia; Female; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Nevirapine; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Risk Factors; Zidovudine

2016
First-line antiretroviral drug discontinuations in children.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Follow-Up Studies; HIV; HIV Infections; Humans; Infant; Kaplan-Meier Estimate; Lopinavir; Outcome Assessment, Health Care; Proportional Hazards Models; Ritonavir; South Africa; Stavudine; Withholding Treatment; Zidovudine

2017
Breast-feeding, antiretroviral prophylaxis, and HIV.
    The New England journal of medicine, 2008, Jul-10, Volume: 359, Issue:2

    Topics: Anti-HIV Agents; Breast Feeding; Female; HIV; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Nevirapine; Weaning; Zidovudine

2008
Restoration of the antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus by delivery of engineered thymidylate kinase to T cells.
    The Journal of general virology, 2008, Volume: 89, Issue:Pt 7

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cell Line; Drug Resistance, Viral; HIV; HIV Core Protein p24; Humans; Kinetics; Models, Molecular; Nucleoside-Phosphate Kinase; Protein Structure, Tertiary; Virus Replication; Zidovudine

2008
Synthesis and in vitro activities of a new antiviral duplex drug linking Zidovudine (AZT) and Foscarnet (PFA) via an octadecylglycerol residue.
    Bioorganic & medicinal chemistry, 2009, Jan-01, Volume: 17, Issue:1

    Topics: Antiviral Agents; Cross-Linking Reagents; Cytomegalovirus; Drug Interactions; Foscarnet; Glyceryl Ethers; HIV; Humans; Inhibitory Concentration 50; Simplexvirus; Zidovudine

2009
Development of a liquid chromatographic assay for an anti-HIV tablet containing lamivudine, zidovudine and TMC278.HCL.
    Journal of pharmaceutical and biomedical analysis, 2009, Feb-20, Volume: 49, Issue:2

    Topics: Anti-HIV Agents; Biological Assay; Calibration; Chemistry, Pharmaceutical; Chromatography, Liquid; HIV; Humans; Lamivudine; Light; Molecular Structure; Nitriles; Pyrimidines; Reference Standards; Rilpivirine; Scattering, Radiation; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Tablets; Zidovudine

2009
Pharmacokinetic-pharmacodynamic relationship of NRTIs and its connection to viral escape: an example based on zidovudine.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Mar-02, Volume: 36, Issue:4-5

    Topics: Animals; Clinical Trials as Topic; Drug Resistance, Viral; HIV; Humans; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

2009
Resistance to antiretrovirals in HIV-infected pregnant women.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, Volume: 45, Issue:1

    Topics: Adult; Anti-HIV Agents; Data Interpretation, Statistical; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Viral Load; Zidovudine

2009
Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.
    The Journal of infectious diseases, 2009, Sep-01, Volume: 200, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Stavudine; Young Adult; Zidovudine

2009
A medical mission to Swaziland, part 2.
    Adler Museum bulletin, 2000, Volume: 26, Issue:2

    Topics: Correspondence as Topic; Delivery of Health Care; Eswatini; Gynecologic Surgical Procedures; Gynecology; History, 20th Century; HIV; Medical Missions; Mortality; Physicians; Travel; Zidovudine

2000
Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine

2010
Reduced dose of stavudine and lipoatrophy in HIV-infected patients in Cameroon.
    Antiviral therapy, 2010, Volume: 15, Issue:7

    Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Male; Middle Aged; Nevirapine; Stavudine; Zidovudine

2010
Adherence to combination prophylaxis for prevention of mother-to-child-transmission of HIV in Tanzania.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Delivery, Obstetric; Drug Therapy, Combination; Female; HIV; HIV Infections; Hospitals; Humans; Infectious Disease Transmission, Vertical; Mothers; Patient Compliance; Pregnancy; Rural Population; Tanzania; Time Factors; Young Adult; Zidovudine

2011
Marvellous chemical biology tools and other matters.
    Chemical biology & drug design, 2012, Volume: 79, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Computational Biology; Drug Design; HIV; Humans; Zidovudine

2012
Interleukin-8 in the pathogenesis of primary central nervous system lymphoma in association with HIV infection.
    Hematology (Amsterdam, Netherlands), 2012, Volume: 17, Issue:3

    Topics: Anti-HIV Agents; CD18 Antigens; Cell Adhesion; Cell Line, Transformed; Cell Line, Tumor; Central Nervous System Neoplasms; Herpesvirus 4, Human; HIV; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Lymphoma, AIDS-Related; Simvastatin; Zidovudine

2012
Expression of oral secretory leukocyte protease inhibitor in HIV-infected subjects with long-term use of antiretroviral therapy.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:3

    Topics: Adult; Alcohol Drinking; Anti-HIV Agents; Anti-Retroviral Agents; Biomarkers; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; Gingival Hemorrhage; HIV; HIV Infections; Humans; Male; Middle Aged; Mouth Mucosa; Oral Health; Periodontal Pocket; Saliva; Salivary Proteins and Peptides; Secretory Leukocyte Peptidase Inhibitor; Secretory Rate; Serine Proteinase Inhibitors; Smoking; Time Factors; Viral Load; Young Adult; Zidovudine

2013
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
    The Journal of infectious diseases, 2013, Volume: 207, Issue:7

    Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cells, Cultured; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Enzyme Activation; Female; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Regression Analysis; Reverse Transcriptase Inhibitors; Risk Factors; Telomerase; Telomere; Telomere Shortening; Tenofovir; Time Factors; Young Adult; Zidovudine

2013
Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11.
    The Biochemical journal, 2002, Nov-15, Volume: 368, Issue:Pt 1

    Topics: Anti-HIV Agents; ATP-Binding Cassette Transporters; Biological Transport; Deoxycytidine Kinase; Drug Resistance, Multiple; HIV; Humans; Lamivudine; Multidrug Resistance-Associated Proteins; Nucleosides; T-Lymphocytes; Tumor Cells, Cultured; Zidovudine

2002
Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine.
    Antiviral therapy, 2002, Volume: 7, Issue:2

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV; Humans; Phosphorylation; RNA, Messenger; Stavudine; T-Lymphocytes; Thymidine Kinase; Time Factors; Zidovudine

2002
Loss of zidovudine related mutations in the reverse transscriptase gene of HIV after switching therapy.
    European journal of medical research, 2002, Sep-30, Volume: 7, Issue:9

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Mutation; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine

2002
Prenatal HIV counseling, testing, and antiretroviral prophylaxis by obstetric and family medicine providers in Alabama.
    The American journal of the medical sciences, 2002, Volume: 324, Issue:6

    Topics: AIDS Serodiagnosis; Alabama; Anti-HIV Agents; Directive Counseling; Family Practice; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Patient Acceptance of Health Care; Patient Education as Topic; Perinatal Care; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Preventive Health Services; United States; Zidovudine

2002
Recommendations to reduce the risk of occupational HIV transmission.
    New Jersey medicine : the journal of the Medical Society of New Jersey, 2003, Volume: 100, Issue:1-2

    Topics: Anti-HIV Agents; Health Occupations; HIV; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; New Jersey; Occupational Diseases; Practice Guidelines as Topic; Risk; Zidovudine

2003
Synthesis and evaluation of novel bioconjugates as antiviral agents.
    Nucleic acids symposium series, 2000, Issue:44

    Topics: Anti-HIV Agents; Base Sequence; DNA, Viral; HIV; Lipids; Molecular Structure; Nucleosides; Oligodeoxyribonucleotides; Zidovudine

2000
Synthesis and antiviral activity of some 5'-N-phthaloyl-3'-azido-2',3'-dideoxythymidine analogues.
    Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:3

    Topics: Animals; Anti-HIV Agents; Cell Transformation, Viral; Cells, Cultured; HIV; Humans; Imides; Mice; Microbial Sensitivity Tests; Prodrugs; Reverse Transcriptase Inhibitors; Sarcoma Viruses, Murine; Virus Replication; Zidovudine

2003
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Cells, Cultured; Dideoxynucleotides; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Neutrophils; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate; Viral Plaque Assay; Zidovudine

2004
Modelling HIV-RNA viral load in vertically infected children.
    Statistics in medicine, 2004, Mar-15, Volume: 23, Issue:5

    Topics: Algorithms; Europe; Female; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Models, Statistical; RNA, Viral; Viral Load; Zidovudine

2004
Can the peripheral blood monocyte count be used as a marker of CSF resistance to antiretroviral drugs?
    Journal of neurovirology, 2004, Volume: 10 Suppl 1

    Topics: Anti-HIV Agents; Biomarkers; Buffers; Culture Media; Dideoxynucleosides; Drug Resistance, Viral; HIV; HIV Infections; Humans; In Vitro Techniques; Leukocyte Count; Monocytes; Stavudine; Zidovudine

2004
Synthesis and evaluation of a novel synthetic phosphocholine lipid-AZT conjugate that double-targets wild-type and drug resistant variants of HIV.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:1-2

    Topics: Antiviral Agents; Drug Resistance, Viral; HIV; HIV Infections; Humans; Malonates; Phosphorylcholine; Zidovudine

2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
    AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12

    Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2004
Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Feb-25, Volume: 816, Issue:1-2

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Drug Stability; HIV; HIV Infections; Humans; Lamivudine; Quality Control; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine

2005
Thymidine kinase and deoxycytidine kinase activity in mononuclear cells from antiretroviral-naive HIV-infected patients.
    AIDS (London, England), 2005, Mar-25, Volume: 19, Issue:5

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Deoxycytidine Kinase; Female; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Middle Aged; RNA, Viral; Thymidine; Thymidine Kinase; Zidovudine

2005
Homo and heterodimers of ddI, d4T and AZT: influence of (5'-5') thiolcabonate-carbamate linkage on anti-HIV activity.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Anti-HIV Agents; Antiviral Agents; Carbamates; Didanosine; Dimerization; HIV; HIV Infections; Models, Chemical; Molecular Conformation; Mutation; Stavudine; Sulfhydryl Compounds; Zidovudine

2005
Aryl nucleoside H-phosphonates. Part 15: Synthesis, properties and, anti-HIV activity of aryl nucleoside 5'-alpha-hydroxyphosphonates.
    Bioorganic & medicinal chemistry, 2006, Mar-15, Volume: 14, Issue:6

    Topics: Anti-HIV Agents; Cell Line; Cells, Cultured; HIV; Humans; Hydroxy Acids; Microbial Sensitivity Tests; Molecular Structure; Organophosphonates; Virus Replication; Zidovudine

2006
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
    The New England journal of medicine, 2006, Jun-08, Volume: 354, Issue:23

    Topics: Adenine; Bone Density; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2006
C34, a membrane fusion inhibitor, blocks HIV infection of langerhans cells and viral transmission to T cells.
    The Journal of investigative dermatology, 2007, Volume: 127, Issue:6

    Topics: Anti-HIV Agents; Antigens, CD34; Cells, Cultured; Chemokine CCL5; Coculture Techniques; Epidermal Cells; Epidermis; Gene Products, gag; HIV; HIV Envelope Protein gp41; HIV Infections; Humans; Langerhans Cells; Membrane Fusion; T-Lymphocytes; Virus Integration; Zidovudine

2007
Prior antiretroviral therapy experience protects against zidovudine-related anaemia.
    HIV medicine, 2007, Volume: 8, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Asia; Developing Countries; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Zidovudine

2007
Decreasing CD4+ T-cell count during suppressed or low-level viraemia in patients with HIV infection.
    Antiviral therapy, 2007, Volume: 12, Issue:7

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Viral Load; Viremia; Zidovudine

2007
Frequent detection of acute HIV infection in pregnant women.
    AIDS (London, England), 2007, Nov-12, Volume: 21, Issue:17

    Topics: Acute Disease; Algorithms; Anti-HIV Agents; Female; Follow-Up Studies; HIV; HIV Infections; HIV Seropositivity; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Mass Screening; North Carolina; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Pregnancy Trimester, Second; Prenatal Care; Prevalence; RNA, Viral; Zidovudine

2007
Characteristics of untreated AIDS-related cytomegalovirus retinitis. II. Findings in the era of highly active antiretroviral therapy (1997 to 2000).
    American journal of ophthalmology, 2008, Volume: 145, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cytomegalovirus Retinitis; Drug Therapy, Combination; Female; HIV; Humans; Los Angeles; Male; Retrospective Studies; RNA, Viral; Urban Population; Zidovudine

2008
Predictors of severe haematological toxicity secondary to pegylated interferon plus ribavirin treatment in HIV-HCV-coinfected patients.
    Antiviral therapy, 2007, Volume: 12, Issue:8

    Topics: Adult; Anemia; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Female; Fibrosis; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Leukocyte Count; Male; Neutropenia; Platelet Count; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Risk Factors; Spain; Thrombocytopenia; Zidovudine

2007
Short communication cellular pharmacology of 9-(beta-D-1,3-dioxolan-4-yl) guanine and its lack of drug interactions with zidovudine in primary human lymphocytes.
    Antiviral chemistry & chemotherapy, 2007, Volume: 18, Issue:6

    Topics: Cells, Cultured; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Guanine; Half-Life; HIV; Humans; Lymphocytes; Mutation; Phosphorylation; Prodrugs; Zidovudine

2007
Rapid scaling-up of antiretroviral therapy in 10,000 adults in Côte d'Ivoire: 2-year outcomes and determinants.
    AIDS (London, England), 2008, Apr-23, Volume: 22, Issue:7

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cote d'Ivoire; Drug Administration Schedule; Female; Follow-Up Studies; HIV; HIV Infections; HIV-1; HIV-2; Humans; Lamivudine; Male; Nevirapine; Survival Analysis; Treatment Outcome; Zidovudine

2008
25 years of HIV.
    Nature, 2008, May-15, Volume: 453, Issue:7193

    Topics: AIDS Vaccines; Anti-HIV Agents; Drug Resistance, Viral; History, 20th Century; History, 21st Century; HIV; HIV Infections; Humans; Time Factors; Zidovudine

2008
Is HIV the cause of AIDS?
    Lancet (London, England), 1995, Nov-18, Volume: 346, Issue:8986

    Topics: Acquired Immunodeficiency Syndrome; Antibodies, Viral; Female; Hemophilia A; HIV; HIV Infections; Humans; Male; Zidovudine

1995
[HIV drug resistance and its genetic basis].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Amino Acid Sequence; Codon; Didanosine; Drug Resistance, Microbial; HIV; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine

1993
Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Antiviral Agents; Benzodiazepines; Didanosine; Drug Synergism; Gene Products, tat; HeLa Cells; HIV; HIV Protease Inhibitors; Humans; Isoquinolines; Nevirapine; Pyridines; Pyrroles; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; tat Gene Products, Human Immunodeficiency Virus; Zalcitabine; Zidovudine

1994
Didanosine resistance in HIV-infected patients switched from zidovudine to didanosine monotherapy.
    Annals of internal medicine, 1994, Aug-15, Volume: 121, Issue:4

    Topics: CD4-Positive T-Lymphocytes; Codon; Didanosine; Drug Resistance, Microbial; Genes, Viral; HIV; HIV Infections; Humans; Leukocyte Count; Mutation; Retrospective Studies; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine

1994
Human immunodeficiency virus reverse transcriptase substitutes for DNA polymerase I in Escherichia coli.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jan-31, Volume: 92, Issue:3

    Topics: DNA Polymerase I; DNA Replication; Drug Evaluation, Preclinical; Escherichia coli; Genetic Complementation Test; HIV; Humans; Mutation; Plasmids; RNA-Directed DNA Polymerase; Temperature; Zidovudine

1995
A screen in Escherichia coli for nucleoside analogs that target human immunodeficiency virus (HIV) reverse transcriptase: coexpression of HIV reverse transcriptase and herpes simplex virus thymidine kinase.
    Journal of virology, 1995, Volume: 69, Issue:10

    Topics: Antiviral Agents; Cloning, Molecular; Cytarabine; DNA Polymerase I; Drug Evaluation, Preclinical; Escherichia coli; Gene Expression; HIV; Kinetics; Phosphorylation; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Simplexvirus; Thymidine Kinase; Zalcitabine; Zidovudine

1995
Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virus.
    The Journal of pediatrics, 1995, Volume: 127, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Cardiomyopathies; CD4 Lymphocyte Count; Child, Preschool; Didanosine; Dose-Response Relationship, Drug; Echocardiography; Female; Heart; HIV; Humans; Infant; Infant, Newborn; Male; Medical Records; Retrospective Studies; Severity of Illness Index; Zalcitabine; Zidovudine

1995
Correlation of clinical progression in human immunodeficiency virus-infected children with in vitro zidovudine resistance measured by a direct quantitative peripheral blood lymphocyte assay.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:2

    Topics: Child; Child, Preschool; Disease Progression; Drug Resistance, Microbial; Follow-Up Studies; HIV; HIV Core Protein p24; HIV Infections; Humans; Infant; Lymphocytes; Microbial Sensitivity Tests; Zidovudine

1995
Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase.
    The Journal of biological chemistry, 1995, Aug-11, Volume: 270, Issue:32

    Topics: Antiviral Agents; Base Sequence; Deoxyribonucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; HIV; Mitochondria; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thymine Nucleotides; Zidovudine

1995
A mutation in human immunodeficiency virus reverse transcriptase and decline in CD4 lymphocyte numbers in long-term zidovudine recipients.
    The Journal of infectious diseases, 1993, Volume: 167, Issue:3

    Topics: CD4-Positive T-Lymphocytes; Codon; DNA, Viral; Drug Resistance; Genes, pol; HIV; HIV Infections; Humans; Leukocyte Count; Longitudinal Studies; Point Mutation; Polymerase Chain Reaction; Proviruses; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine

1993
Triple whammy. Will an AIDS therapy live up to its advance billing?
    Scientific American, 1993, Volume: 268, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; Didanosine; Drug Therapy, Combination; HIV; Humans; Nevirapine; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1993
Early identification of human immunodeficiency virus-infected asymptomatic subjects susceptible to zidovudine by quantitative viral coculture and reverse transcription-linked polymerase chain reaction.
    The Journal of infectious diseases, 1993, Volume: 167, Issue:5

    Topics: Base Sequence; DNA, Viral; HIV; HIV Seropositivity; Humans; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Transcription, Genetic; Zidovudine

1993
Can combination therapy overcome drug resistance?
    Science (New York, N.Y.), 1993, May-28, Volume: 260, Issue:5112

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; Humans; RNA-Directed DNA Polymerase; Zidovudine

1993
AIDS drugs. Harvard group makes a splash--twice.
    Science (New York, N.Y.), 1993, Aug-06, Volume: 261, Issue:5122

    Topics: Antiviral Agents; Didanosine; HIV; Mutation; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1993
Resisting the temptation.
    Lancet (London, England), 1993, Aug-21, Volume: 342, Issue:8869

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Combinations; HIV; Humans; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine

1993
[Inhibition of human immunodeficiency virus replication by azidothymidine (Azitidín Lachema) in cultured cells].
    Bratislavske lekarske listy, 1993, Volume: 94, Issue:2

    Topics: Cell Line; Cytopathogenic Effect, Viral; HIV; HIV Antigens; Humans; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine

1993
Evaluation of the combination effect of different antiviral compounds against HIV in vitro.
    Scandinavian journal of infectious diseases, 1993, Volume: 25, Issue:3

    Topics: Antiviral Agents; Benzodiazepines; Didanosine; Dideoxynucleosides; Drug Combinations; Drug Evaluation; Drug Synergism; HIV; Humans; Imidazoles; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1993
Phosphatidylazidothymidine and phosphatidyl-ddC: assessment of uptake in mouse lymphoid tissues and antiviral activities in human immunodeficiency virus-infected cells and in Rauscher leukemia virus-infected mice.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:12

    Topics: Animals; Female; HIV; Lymphoid Tissue; Mice; Mice, Inbred BALB C; Phospholipids; Prodrugs; Rauscher Virus; Zalcitabine; Zidovudine

1994
Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudine-didanosine combination therapy.
    Journal of virology, 1995, Volume: 69, Issue:6

    Topics: Base Sequence; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; Humans; Molecular Sequence Data; RNA, Viral; Zidovudine

1995
Serum HIV-1 RNA and routine patient monitoring.
    Lancet (London, England), 1995, Jun-03, Volume: 345, Issue:8962

    Topics: Drug Resistance; HIV; HIV Infections; Humans; Zidovudine

1995
Synthesis of a photoaffinity analog of 3'-azidothymidine, 5-azido-3'-azido-2',3'-dideoxyuridine. Interactions with herpesvirus thymidine kinase and cellular enzymes.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Affinity Labels; Animals; Antiviral Agents; Herpesvirus 1, Human; HIV; Microsomes, Liver; Rats; Thymidine Kinase; Zidovudine

1995
The predictive value of T cell function in vitro and pre-AIDS zidovudine use for survival after AIDS diagnosis in a cohort of homosexual men in Amsterdam.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Age Factors; Analysis of Variance; Antigens, CD; Biomarkers; CD4-CD8 Ratio; Cells, Cultured; Cohort Studies; Follow-Up Studies; HIV; HIV Seropositivity; Homosexuality, Male; Humans; Lymphocyte Activation; Male; Multivariate Analysis; Netherlands; Predictive Value of Tests; Prognosis; Prospective Studies; Survival Analysis; T-Lymphocyte Subsets; T-Lymphocytes; Time Factors; Zidovudine

1995
Mathematical modelling of chemotherapy in HIV infection.
    Folia biologica, 1994, Volume: 40, Issue:3

    Topics: CD4 Lymphocyte Count; HIV; HIV Infections; Humans; Models, Biological; Survival Analysis; Virus Replication; Zidovudine

1994
Synthesis of some new 1,6-dihydro-3-substituted 6-spiro-(9'-fluorene)-1,2,4-triazin-5-(4H)-ones as potential anti HIV and anticancer drugs.
    Die Pharmazie, 1994, Volume: 49, Issue:10

    Topics: Antineoplastic Agents; Antiviral Agents; Drug Screening Assays, Antitumor; HIV; Humans; Spiro Compounds; Triazines; Tumor Cells, Cultured; Zidovudine

1994
"The Duesberg phenomenon": Duesberg and other voices.
    Science (New York, N.Y.), 1995, Jan-20, Volume: 267, Issue:5196

    Topics: Acquired Immunodeficiency Syndrome; HIV; Homosexuality, Male; Humans; Male; Research; Zidovudine

1995
Synthesis of some new heterobicyclic compounds containing spiro-1,2,4-triazine moiety as potential anti-HIV and anticancer agents.
    Die Pharmazie, 1994, Volume: 49, Issue:11

    Topics: Antineoplastic Agents; Antiviral Agents; HIV; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Triazines; Tumor Cells, Cultured; Zidovudine

1994
AIDS mood upbeat--for a change.
    Science (New York, N.Y.), 1995, Feb-17, Volume: 267, Issue:5200

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Gene Products, nef; Herpesviridae; HIV; Humans; Lamivudine; nef Gene Products, Human Immunodeficiency Virus; Sarcoma, Kaposi; Simian Immunodeficiency Virus; Virus Replication; Zalcitabine; Zidovudine

1995
Quasispecies dynamics and the emergence of drug resistance during zidovudine therapy of HIV infection.
    AIDS (London, England), 1994, Volume: 8, Issue:3

    Topics: CD4-Positive T-Lymphocytes; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Genes, pol; HIV; HIV Infections; Humans; Leukocyte Count; Models, Biological; Mutation; Population Dynamics; Species Specificity; Virus Replication; Zidovudine

1994
Inhibitory effect of the oral immune response modifier, bestatin, on cell-mediated and cell-free HIV infection in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1994, Volume: 48, Issue:2

    Topics: Anti-Bacterial Agents; CD4-Positive T-Lymphocytes; Cell Division; Cell-Free System; Dextran Sulfate; HIV; HIV Infections; Immunity, Cellular; Immunologic Factors; In Vitro Techniques; Leucine; Virus Replication; Zidovudine

1994
Quantification of HIV by PCR in monocytes and lymphocytes in patients receiving antiviral treatment and low dose recombinant human granulocyte macrophage colony stimulating factor.
    Journal of clinical pathology, 1994, Volume: 47, Issue:9

    Topics: Adult; Autoradiography; DNA, Viral; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; HIV Infections; Humans; Lymphocytes; Male; Monocytes; Pilot Projects; Polymerase Chain Reaction; Zidovudine

1994
The Duesberg phenomenon.
    Science (New York, N.Y.), 1994, Dec-09, Volume: 266, Issue:5191

    Topics: Acquired Immunodeficiency Syndrome; History, 20th Century; HIV; Humans; Illicit Drugs; Publishing; Zidovudine

1994
Anti-HIV michellamines from Ancistrocladus korupensis.
    Journal of medicinal chemistry, 1994, Jun-10, Volume: 37, Issue:12

    Topics: Africa; Antiviral Agents; Cells, Cultured; Drug Interactions; HIV; HIV-1; HIV-2; Humans; Isoquinolines; Microbial Sensitivity Tests; Molecular Structure; Naphthalenes; Plants; Virus Replication; Zidovudine

1994
Synthesis and antiviral activity of 3'-azido-3'-deoxythymidine triphosphate distearoylglycerol: a novel phospholipid conjugate of the anti-HIV agent AZT.
    Chemistry and physics of lipids, 1994, Apr-19, Volume: 70, Issue:2

    Topics: Antiviral Agents; Dideoxynucleotides; HeLa Cells; HIV; HIV Infections; Humans; Phosphatidic Acids; Zidovudine

1994
Transmission of zidovudine-resistant HIV during a bloody fight.
    JAMA, 1994, Aug-10, Volume: 272, Issue:6

    Topics: Adult; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Male; Violence; Zidovudine

1994
Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine.
    Biochemical pharmacology, 1994, Jul-05, Volume: 48, Issue:1

    Topics: Antiviral Agents; Cell Line; Dideoxyadenosine; Drug Evaluation, Preclinical; HIV; Humans; T-Lymphocytes; Virus Replication; Zidovudine

1994
A screening model of anti-HIV non AZT cross resistance virostatics.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1993, Volume: 47, Issue:10

    Topics: Antiviral Agents; Drug Resistance; HIV; Humans; Mass Screening; Models, Statistical; Virology; Zidovudine

1993
In vitro activity of inhibitors of late stages of the replication of HIV in chronically infected macrophages.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:3

    Topics: Cells, Cultured; HIV; HIV Protease Inhibitors; Humans; Interferon-alpha; Macrophage Colony-Stimulating Factor; Macrophages; Virus Replication; Zidovudine

1994
Long-term treatment with zidovudine in patients with human immunodeficiency virus (HIV)-associated thrombocytopenia: modes of response and correlation with markers of HIV replication.
    European journal of haematology, 1993, Volume: 50, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; CD4-Positive T-Lymphocytes; Female; HIV; Humans; Leukocyte Count; Male; Platelet Count; Thrombocytopenia; Virus Replication; Zidovudine

1993
Measurement of HIV virus load and genotypic resistance by gene amplification in asymptomatic subjects treated with combination therapy.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:4

    Topics: CD4-Positive T-Lymphocytes; Codon; Didanosine; Drug Therapy, Combination; Gene Amplification; Genes, Viral; HIV; HIV Infections; Humans; Leukocyte Count; RNA, Viral; Zidovudine

1993
Solid-state and solution conformations of the potent HIV inhibitor, 4'-azidothymidine.
    Journal of medicinal chemistry, 1994, Feb-18, Volume: 37, Issue:4

    Topics: Antiviral Agents; Crystallography, X-Ray; HIV; Magnetic Resonance Spectroscopy; Molecular Conformation; Stereoisomerism; Zidovudine

1994
Prophylactic zalcitabine and interferon-alpha for a large-bore needlestick exposure to human immunodeficiency virus.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:4

    Topics: Adult; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Interferon alpha-2; Interferon-alpha; Needlestick Injuries; Recombinant Proteins; Zalcitabine; Zidovudine

1994
[What is the future of antiviral therapy of HIV-infected patients? Reports of results of antiretroviral therapy studies at the IX. World Congress on AIDS in Berlin].
    Zeitschrift fur arztliche Fortbildung, 1993, Dec-12, Volume: 87, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Berlin; HIV; HIV Infections; Humans; Zidovudine

1993
Comparative embryonic cytotoxicity of antiretroviral nucleosides.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:5

    Topics: Animals; Antiviral Agents; Culture Techniques; Didanosine; Embryo, Mammalian; HIV; Mice; Nucleosides; Stavudine; Zalcitabine; Zidovudine

1994
3'-Azido-3'-deoxythymidine potently inhibits protein glycosylation. A novel mechanism for AZT cytotoxicity.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Animals; CHO Cells; Cricetinae; Cytidine Monophosphate N-Acetylneuraminic Acid; Dideoxynucleotides; Glycosylation; Golgi Apparatus; HIV; HIV Infections; Humans; Intracellular Membranes; Kinetics; Membrane Proteins; Nucleoside Diphosphate Sugars; Protein Processing, Post-Translational; Thymine Nucleotides; Uridine Diphosphate Galactose; Uridine Diphosphate N-Acetylglucosamine; Zidovudine

1994
Cystamine potently suppresses in vitro HIV replication in acutely and chronically infected human cells.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:5

    Topics: Antiviral Agents; Cells, Cultured; Cystamine; DNA Replication; Dose-Response Relationship, Drug; HIV; HIV Core Protein p24; Humans; Lymphocytes; Macrophages; Proviruses; Viral Proteins; Virus Replication; Zidovudine

1994
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9

    Topics: Aminoisobutyric Acids; Animals; Antiviral Agents; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Feces; HIV; In Vitro Techniques; Injections, Intravenous; Injections, Subcutaneous; Liver; Macaca fascicularis; Macaca mulatta; Rats; Rats, Sprague-Dawley; Stavudine; Thymine; Zidovudine

1993
Persistence of four related human immunodeficiency virus subtypes during the course of zidovudine therapy: relationship between virion RNA and proviral DNA.
    Journal of virology, 1994, Volume: 68, Issue:1

    Topics: Amino Acid Sequence; Consensus Sequence; DNA, Complementary; DNA, Viral; Genetic Variation; Glycosylation; HIV; HIV Infections; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Protein Processing, Post-Translational; Proviruses; RNA, Viral; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Time Factors; Virion; Zidovudine

1994
Smoothed nonparametric back-projection of AIDS incidence data with adjustment for therapy.
    Mathematical biosciences, 1993, Volume: 118, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Australia; HIV; HIV Infections; Humans; Incidence; Mathematics; Models, Statistical; Zidovudine

1993
'U' discovers transmission of AZT-resistant AIDS.
    Minnesota medicine, 1993, Volume: 76, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Drug Resistance; HIV; Humans; Zidovudine

1993
AZT patent. Court favors drug 'concept' over proof.
    Science (New York, N.Y.), 1993, Jul-30, Volume: 261, Issue:5121

    Topics: Acquired Immunodeficiency Syndrome; Drug Industry; HIV; Humans; Patents as Topic; United States; Zidovudine

1993
Cell-to-cell transmission of human immunodeficiency virus infection induces two distinct phases of viral RNA expression under separate regulatory control.
    The Journal of general virology, 1993, Volume: 74 ( Pt 1)

    Topics: Cell Line; Gene Expression Regulation, Viral; HIV; HIV Infections; Humans; RNA, Viral; Time Factors; Transcription, Genetic; Zidovudine

1993
Does zidovudine reduce tumour necrosis factor-alpha in HIV-positive patients?
    AIDS (London, England), 1993, Volume: 7, Issue:1

    Topics: HIV; HIV Infections; Humans; Tumor Necrosis Factor-alpha; Virus Replication; Zidovudine

1993
A disappointing decade of AIDS.
    Nature, 1993, Mar-04, Volume: 362, Issue:6415

    Topics: Acquired Immunodeficiency Syndrome; Africa; Antiviral Agents; Child; Forecasting; HIV; HIV Infections; Humans; Zidovudine

1993
Study of human immunodeficiency virus resistance to 2'-3'-dideoxyinosine and zidovudine in sequential isolates from pediatric patients on long-term therapy.
    The Journal of infectious diseases, 1993, Volume: 167, Issue:4

    Topics: Child; Child, Preschool; Dideoxyadenosine; Drug Resistance, Microbial; Female; HIV; HIV Seropositivity; Humans; Infant; Male; Zidovudine

1993
A tale of two mutants.
    The New England journal of medicine, 1993, Apr-22, Volume: 328, Issue:16

    Topics: Antitubercular Agents; Drug Resistance; HIV; HIV Infections; Humans; Mutation; Mycobacterium tuberculosis; Tuberculosis, Pulmonary; Zidovudine

1993
Syringe attack by AIDS patient may be first documented.
    The American nurse, 1993, Volume: 25, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Female; HIV; HIV Infections; Humans; Needlestick Injuries; Nursing Staff, Hospital; Occupational Exposure; Violence; Zidovudine

1993
In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:4

    Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Drug Resistance, Microbial; Gene Products, gag; HIV; HIV Protease Inhibitors; HIV-1; HIV-2; Humans; Oligopeptides; Phenylbutyrates; Protein Precursors; Protein Processing, Post-Translational; Radioimmunoprecipitation Assay; Zidovudine

1993
Identification of a novel human immunodeficiency virus strain cytopathic to megakaryocytic cells.
    Blood, 1993, Jun-15, Volume: 81, Issue:12

    Topics: Antibodies, Monoclonal; CD4 Antigens; Cell Survival; Cytopathogenic Effect, Viral; HIV; HIV Envelope Protein gp120; Humans; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Polymerase Chain Reaction; Tumor Cells, Cultured; Virus Replication; Zidovudine

1993
Response: arguments contradict the "foreign protein-zidovudine" hypothesis.
    BMJ (Clinical research ed.), 1996, Jan-27, Volume: 312, Issue:7025

    Topics: Acquired Immunodeficiency Syndrome; Factor VIII; Hemophilia A; HIV; HIV Seropositivity; Humans; Risk Factors; Zidovudine

1996
From pseudocholinesterase to human immunodeficiency virus.
    Medical hypotheses, 1995, Volume: 45, Issue:3

    Topics: Animals; Antibodies; Apolipoproteins E; Biochemistry; Butyrylcholinesterase; Chloroquine; Drug Carriers; Endocytosis; Enzyme Activation; HIV; HIV Antibodies; HIV Envelope Protein gp120; HIV Infections; HIV Reverse Transcriptase; Humans; Immunoconjugates; Immunotherapy; Liposomes; Liver; Low Density Lipoprotein Receptor-Related Protein-1; Lysosomes; Mammals; Receptors, Lipoprotein; RNA-Directed DNA Polymerase; Zidovudine

1995
Tumor necrosis factor-alpha in serum of macaques during SIVmac251 acute infection.
    Journal of medical primatology, 1995, Volume: 24, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Biomarkers; Disease Models, Animal; Female; HIV; Humans; Macaca fascicularis; Male; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Time Factors; Tumor Necrosis Factor-alpha; Viremia; Virus Replication; Zidovudine

1995
SC-52151, a novel inhibitor of the human immunodeficiency virus protease.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:10

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Dogs; Drug Synergism; HIV; HIV Protease Inhibitors; Humans; Macaca mulatta; Molecular Sequence Data; Protein Binding; Rats; Rats, Sprague-Dawley; Urea; Zidovudine

1995
Update: provisional Public Health Service recommendations for chemoprophylaxis after occupational exposure to HIV.
    MMWR. Morbidity and mortality weekly report, 1996, Jun-07, Volume: 45, Issue:22

    Topics: Antiviral Agents; Blood-Borne Pathogens; Chemoprevention; HIV; HIV Infections; Humans; Occupational Exposure; United States; United States Public Health Service; Zidovudine

1996
In vivo drug screening applications of HIV-infected cells cultivated within hollow fibers in two physiologic compartments of mice.
    Antiviral research, 1995, Volume: 28, Issue:3

    Topics: Animals; Antiviral Agents; Cells, Cultured; Drug Evaluation, Preclinical; HIV; HIV Core Protein p24; Humans; Mice; Mice, SCID; RNA-Directed DNA Polymerase; Virus Cultivation; Virus Replication; Zalcitabine; Zidovudine

1995
From the Centers for Disease Control and Prevention. Update: provisional public health service recommendations for chemoprophylaxis after occupational exposure to HIV.
    JAMA, 1996, Jul-10, Volume: 276, Issue:2

    Topics: Antiviral Agents; Blood-Borne Pathogens; Chemoprevention; HIV; HIV Infections; Humans; Occupational Exposure; United States; United States Public Health Service; Zidovudine

1996
NMR study of dideoxynucleotides with anti-human immunodeficiency virus (HIV) activity.
    Journal of biochemical and biophysical methods, 1996, Feb-05, Volume: 31, Issue:3-4

    Topics: Antiviral Agents; Dideoxynucleotides; HIV; Humans; Inosine Triphosphate; Magnetic Resonance Spectroscopy; Models, Theoretical; Molecular Conformation; Molecular Structure; Thymine Nucleotides; Zidovudine

1996
[Zidovudine-resistant HIV strains in intravenous drug users and homosexual men in Amsterdam].
    Nederlands tijdschrift voor geneeskunde, 1996, Apr-27, Volume: 140, Issue:17

    Topics: Cohort Studies; Drug Resistance; HIV; HIV Infections; Homosexuality; Humans; Male; Point Mutation; Substance Abuse, Intravenous; Zidovudine

1996
[Action of drugs based on native DNA against RNA and DNA containing viruses].
    Klinicheskaia meditsina, 1995, Volume: 73, Issue:6

    Topics: Animals; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Ganciclovir; HIV; Humans; Interferon Inducers; Mice; RNA, Double-Stranded; RNA, Fungal; Simplexvirus; Zidovudine

1995
New guidelines set for occupational HIV exposure.
    Lancet (London, England), 1996, Jul-06, Volume: 348, Issue:9019

    Topics: Accidents, Occupational; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Practice Guidelines as Topic; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
[Resistance and combined use of anti-HIV drugs].
    Revista da Sociedade Brasileira de Medicina Tropical, 1995, Volume: 28 Suppl 2

    Topics: Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Mutation; Zalcitabine; Zidovudine

1995
Selective protection of toxicity of 2',3'-dideoxypyrimidine nucleoside analogs by beta-D-uridine in human granulocyte-macrophage progenitor cells.
    Antiviral research, 1996, Volume: 29, Issue:2-3

    Topics: Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Dideoxynucleosides; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Molecular Structure; Uridine; Zidovudine

1996
Complete inhibition of viral breakthrough by combination of MKC-442 with AZT during a long-term culture of HIV-1 infected cells.
    Antiviral research, 1996, Volume: 31, Issue:1-2

    Topics: Acetamides; Acetophenones; Cell Line, Transformed; HIV; HIV Core Protein p24; HIV-1; Humans; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Uracil; Zidovudine

1996
Sulfated colominic acid: an antiviral agent that inhibits the human immunodeficiency virus type 1 in vitro.
    Antiviral research, 1996, Volume: 31, Issue:1-2

    Topics: Anti-HIV Agents; CD4 Antigens; Cell Line; Cell Line, Transformed; Drug Synergism; Flow Cytometry; Giant Cells; HIV; HIV Antigens; HIV Core Protein p24; HIV-1; Humans; Polysaccharides; RNA-Directed DNA Polymerase; Sulfates; T-Lymphocytes; Tumor Cells, Cultured; Zidovudine

1996
Therapy of HIV infections: problems and prospects.
    Bulletin of the New York Academy of Medicine, 1996,Summer, Volume: 73, Issue:1

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Stavudine; Urban Health; Zalcitabine; Zidovudine

1996
The effect of zidovudine on skeletal muscle mtDNA in HIV-1 infected patients with mild or no muscle dysfunction.
    Brain : a journal of neurology, 1996, Volume: 119 ( Pt 4)

    Topics: Adult; Base Sequence; DNA; Female; HIV; Humans; Male; Mitochondria; Molecular Sequence Data; Muscle, Skeletal; Neuromuscular Diseases; Zidovudine

1996
Use of viral resistance patterns to antiretroviral drugs in optimising selection of drug combinations and sequences.
    Drugs, 1996, Volume: 52, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; Humans; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine

1996
PHS updates guidelines on chemoprophylaxis after occupational HIV exposure.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Aug-01, Volume: 53, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Female; Guidelines as Topic; Health Personnel; HIV; Humans; Male; Needlestick Injuries; Occupational Exposure; Zidovudine

1996
[HIV: less resistance due to combined treatment].
    Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49

    Topics: Adult; Anti-HIV Agents; Computer Graphics; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Time Factors; Zidovudine

1996
[HIV: to administer protease inhibitors early].
    Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Time Factors; Zalcitabine; Zidovudine

1996
[Nevirapine: a new principle of action against HIV].
    Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Clinical Trials as Topic; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infant, Newborn; Male; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pyridines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

1996
[Prevalence of transmission of zidovudine-resistant viruses in Switzerland. l'Etude suisse de cohorte VIH].
    Schweizerische medizinische Wochenschrift, 1996, Oct-26, Volume: 126, Issue:43

    Topics: Adolescent; Adult; Antiviral Agents; Base Sequence; DNA, Viral; Drug Resistance; Female; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Male; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Retrospective Studies; Zidovudine

1996
Correspondence between the effect of zidovudine plus lamivudine on plasma HIV level/CD4 lymphocyte count and the incidence of clinical disease in infected individuals. North American Lamivudine HIV Working Group.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

1997
Phenotypic variations and switches in HIV isolated from the blood and the gastrointestinal tissues of patients with HIV-1 infection. HIV/GI Research Study Group.
    Journal of medical virology, 1997, Volume: 52, Issue:1

    Topics: Biopsy; Didanosine; Digestive System; Female; Giant Cells; HIV; HIV Enteropathy; HIV Infections; Humans; Male; Mutation; Phenotype; Prospective Studies; Stavudine; Viral Load; Zidovudine

1997
Low infant infection rate halts study of perinatal HIV transmission.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, May-01, Volume: 54, Issue:9

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Female; HIV; HIV Infections; Humans; Immunization, Passive; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Zidovudine

1997
HIV dementia and apolipoprotein E.
    Acta neurologica Scandinavica, 1997, Volume: 95, Issue:5

    Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Apolipoproteins E; Base Sequence; Electrophoresis, Agar Gel; Encephalitis, Viral; Female; Gene Amplification; Genotype; HIV; Humans; Male; Molecular Sequence Data; Polymerase Chain Reaction; Zidovudine

1997
Human T cell lymphotropic virus type I does not increase human immunodeficiency virus viral load in vivo.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:2

    Topics: Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; HIV; HIV Infections; HTLV-I Infections; Humans; Polymerase Chain Reaction; RNA, Viral; Viral Load; Zidovudine

1997
A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml.
    Nucleic acids research, 1997, Aug-01, Volume: 25, Issue:15

    Topics: Adenosine; Anti-HIV Agents; Cytidine; DNA; DNA, Viral; Drug Therapy, Combination; Guanosine; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Nelfinavir; Nucleic Acid Hybridization; RNA, Viral; Sulfonic Acids; Zidovudine

1997
Antiretroviral resistance and HIV vertical transmission.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1997, Volume: 421

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Female; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

1997
CD8 T-cell response to antiretroviral therapy.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Jun-01, Volume: 15, Issue:2

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lymphocyte Count; T-Lymphocytes, Cytotoxic; Zidovudine

1997
Cure or control of HIV/AIDS?
    Medical hypotheses, 1997, Volume: 48, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1997
The existence of human immunodeficiency virus resistance to nucleoside-analog drugs has not been shown.
    Medical hypotheses, 1997, Volume: 49, Issue:3

    Topics: Anti-HIV Agents; Artifacts; Drug Resistance, Microbial; HIV; Humans; Microbial Sensitivity Tests; Models, Biological; Nucleosides; Zidovudine

1997
[Once-daily administration of didanosine in combination with anti-retroviral zidovudine in previously untreated patients].
    Pathologie-biologie, 1997, Volume: 45, Issue:5

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; RNA, Viral; Zidovudine

1997
Viral phenotype, antiretroviral resistance and clinical evolution in human immunodeficiency virus-infected children.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:11

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug Resistance; Female; HIV; HIV Infections; Humans; Infant; Male; Mutation; Phenotype; Prospective Studies; Zidovudine

1997
Human immunodeficiency virus infection impairs hemopoiesis in long-term bone marrow cultures: nonreversal by nucleoside analogues.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:6

    Topics: Anti-HIV Agents; Antigens, CD34; Apoptosis; Bone Marrow Cells; Cell Death; Cells, Cultured; Didanosine; Hematopoiesis; Hematopoietic Stem Cells; HIV; HIV Core Protein p24; Humans; Stromal Cells; Zidovudine

1997
Lack of antiretroviral effect of alpha-interferon in HIV-infected patients treated for chronic hepatitis C.
    The Journal of infection, 1997, Volume: 35, Issue:3

    Topics: Adult; Drug Therapy, Combination; Female; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Interferon Type I; Male; Middle Aged; Virus Replication; Zidovudine

1997
Visceral leishmaniasis in patients infected with the human immunodeficiency virus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1997, Volume: 16, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Allopurinol; Amebicides; Amphotericin B; Analysis of Variance; Anti-HIV Agents; Antimetabolites; Antimony; Antiprotozoal Agents; Blood; Bone Marrow; CD4-Positive T-Lymphocytes; Cerebrospinal Fluid; Didanosine; Digestive System; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Hepatic Encephalopathy; HIV; Humans; Intestinal Mucosa; Leishmaniasis, Visceral; Lymphocyte Count; Male; Myocarditis; Neutrophils; Pancreatitis; Pentamidine; Renal Insufficiency; Spain; Zidovudine

1997
[Zidovudine-resistant HIV strains in untreated intravenous drug users and homosexual men in Amsterdam infected in 1996].
    Nederlands tijdschrift voor geneeskunde, 1997, Oct-18, Volume: 141, Issue:42

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV; HIV Infections; Homosexuality, Male; Humans; Male; Substance Abuse, Intravenous; Zidovudine

1997
Asymmetric synthesis of 4'-alpha-alkylcarbovir derivatives.
    Nucleic acids symposium series, 1997, Issue:37

    Topics: Alkylation; Anti-HIV Agents; Dideoxynucleosides; HIV; Indicators and Reagents; Molecular Structure; Zidovudine

1997
Determinants of progression to AIDS in HIV-infected individuals: an update from the Italian Seroconversion Study.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Volume: 17 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Anti-HIV Agents; Cohort Studies; Disease Progression; Female; HIV; Humans; Italy; Male; Middle Aged; Zidovudine

1998
Inhibition by 3'-azido-3'-deoxythymidine (AZT) of Trypanosoma cruzi growth in mammalian cells and a possible mechanism of action.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Animals; Antiprotozoal Agents; Dideoxynucleosides; HeLa Cells; HIV; Humans; Mammals; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Trypanosoma cruzi; Zidovudine

1998
The expression of the essential nuclear splicing factor SC35 is altered by human immunodeficiency virus infection.
    Virus research, 1998, Volume: 53, Issue:1

    Topics: Anti-HIV Agents; Blotting, Northern; Cell Nucleus; DNA, Complementary; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Gene Expression; HIV; Humans; Microscopy, Confocal; Nuclear Proteins; Ribonucleoproteins; RNA Splicing; RNA, Messenger; Serine-Arginine Splicing Factors; T-Lymphocytes; Time Factors; Tumor Cells, Cultured; Virus Replication; Zidovudine

1998
Antiretroviral triple therapy decreases HIV viral load but does not alter hepatitis C virus (HCV) serum levels in HIV-HCV-co-infected haemophiliacs.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Hemophilia A; Hepacivirus; Hepatitis C; HIV; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1998
A mixed model for repeated dilution assays.
    Biometrics, 1998, Volume: 54, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Models, Statistical; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reproducibility of Results; Viral Load; Zalcitabine; Zidovudine

1998
[Resistance of human immunodeficiency virus (HIV) to zidovudine. Genotypic analysis in strains isolated from Chilean patients].
    Revista medica de Chile, 1998, Volume: 126, Issue:1

    Topics: Anti-HIV Agents; Chile; Codon; Drug Resistance; Follow-Up Studies; Genotype; HIV; HIV Infections; Humans; Mutation; Prospective Studies; Zidovudine

1998
Long-term suppression of HIV replication in patients with sustained benefit on zidovudine monotherapy.
    AIDS (London, England), 1998, May-28, Volume: 12, Issue:8

    Topics: Anti-HIV Agents; Follow-Up Studies; HIV; HIV Infections; Humans; Proviruses; RNA, Viral; Virus Replication; Zidovudine

1998
A pharmacokinetic-pharmacodynamic model of chemotherapy of human immunodeficiency virus infection that relates development of drug resistance to treatment intensity.
    Journal of pharmacokinetics and biopharmaceutics, 1997, Volume: 25, Issue:6

    Topics: Anti-HIV Agents; CD4-CD8 Ratio; Dose-Response Relationship, Drug; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Models, Theoretical; Nelfinavir; Zidovudine

1997
Chemoprophylaxis after occupational exposure to human immunodeficiency virus in forensic autopsy.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1998, Volume: 52, Issue:2

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Forensic Medicine; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Occupational Exposure; Zidovudine

1998
[AIDS drug in the correct form].
    Deutsche medizinische Wochenschrift (1946), 1998, Sep-04, Volume: 123, Issue:36

    Topics: Anti-HIV Agents; HIV; HIV Infections; Humans; Molecular Conformation; National Institutes of Health (U.S.); Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; United States; Zidovudine

1998
[New trends in HIV].
    Deutsche medizinische Wochenschrift (1946), 1998, Sep-18, Volume: 123, Issue:38

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lipodystrophy; Reverse Transcriptase Inhibitors; Zidovudine

1998
Further characterization of HIV RNA synthesis early after cell-to-cell transmission infection.
    Archives of virology, 1998, Volume: 143, Issue:10

    Topics: Aphidicolin; Dactinomycin; DNA, Viral; HIV; Humans; RNA, Viral; Zidovudine

1998
Dynamics of provirus load and lymphocyte subsets after interleukin 2 treatment in HIV-infected patients.
    AIDS research and human retroviruses, 1999, Jan-20, Volume: 15, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Female; HIV; Humans; Interleukin-2; Male; Polymerase Chain Reaction; Proviruses; Recombinant Proteins; T-Lymphocyte Subsets; Viral Load; Zidovudine

1999
Synthesis of dual function (5R,6R)- and (5S,6S)-5-bromo-6-methoxy-5,6-dihydro-AZT-5'-(para-bromophenyl methoxyalaninyl phosphate) as novel spermicidal and anti-HIV agents.
    Antiviral chemistry & chemotherapy, 1999, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Contraceptive Devices, Female; Dideoxynucleotides; Female; HIV; HIV Infections; Humans; Male; Nonoxynol; Organophosphorus Compounds; Spermatocidal Agents; Spermatozoa; Virus Replication; Zidovudine

1999
Antiretroviral drugs: new agents, new combinations line up against HIV.
    Hospital technology series, 1996, Volume: 15, Issue:1

    Topics: Antiviral Agents; Australia; Didanosine; Drug Therapy, Combination; Europe; HIV; HIV Infections; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine

1996
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
    Molecular pharmacology, 1999, Volume: 56, Issue:4

    Topics: Amino Acids; Animals; Anti-HIV Agents; Biotransformation; Dideoxynucleotides; Drug Design; Esterases; Esters; HIV; Humans; Liver; Male; Mice; Nucleosides; Prodrugs; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine

1999
Use of recombinant viruses to assess the pattern of early human immunodeficiency virus breakthrough infection in the presence of stavudine.
    The Journal of general virology, 1999, Volume: 80 ( Pt 9)

    Topics: Animals; Anti-HIV Agents; COS Cells; Defective Viruses; Floxuridine; HeLa Cells; HIV; Humans; Jurkat Cells; Leukemia Virus, Murine; Recombination, Genetic; Stavudine; Zidovudine

1999
Drug-antibody conjugates with anti-HIV activity.
    Biochemical pharmacology, 1999, Dec-01, Volume: 58, Issue:11

    Topics: Amino Acid Sequence; Anti-HIV Agents; Glycoproteins; HIV; HIV Antibodies; HIV Envelope Protein gp120; Humans; Immunoconjugates; Immunodeficiency Virus, Feline; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Molecular Sequence Data; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured; Virus Replication; Zidovudine

1999
Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens.
    JAMA, 2000, Jan-12, Volume: 283, Issue:2

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Phenotype; RNA, Viral; Treatment Failure; Viral Load; Zidovudine

2000
[HIV-1 (human immunodeficiency virus type 1) mutant strain associated with zidovudine resistance detected from a Japanese patient with primary HIV-1 infection].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2000, Volume: 74, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; HIV; Humans; Japan; Mutation; Zidovudine

2000
Emergence of zidovudine resistance in HIV-infected patients receiving stavudine.
    Journal of acquired immune deficiency syndromes (1999), 2000, Mar-01, Volume: 23, Issue:3

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Stavudine; Zidovudine

2000
Cutaneous side effects induced by indinavir.
    European journal of dermatology : EJD, 2000, Volume: 10, Issue:4

    Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine

2000
Failure to develop HIV infection after receipt of HIV-contaminated blood and postexposure prophylaxis.
    Annals of internal medicine, 2000, Jul-04, Volume: 133, Issue:1

    Topics: Adolescent; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Transfusion Reaction; Zidovudine

2000
Mbeki gives AIDS scientists the cold shoulder.
    Nature, 2000, Jul-13, Volume: 406, Issue:6792

    Topics: Acquired Immunodeficiency Syndrome; Adult; Breast Feeding; Enzyme-Linked Immunosorbent Assay; Female; Government; HIV; Humans; Infectious Disease Transmission, Vertical; Male; Middle Aged; Nevirapine; Poverty; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Infectious; South Africa; Zidovudine

2000
Correlation between human immunodeficiency virus genotypic resistance and virologic response in patients receiving nelfinavir monotherapy or nelfinavir with lamivudine and zidovudine.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Mutation; Nelfinavir; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine

2000
LuSIV cells: a reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication.
    Virology, 2000, Aug-01, Volume: 273, Issue:2

    Topics: Cell Line; Cells, Cultured; Genes, Reporter; Genes, tat; HIV; Humans; Luciferases; Plasmids; Simian Immunodeficiency Virus; Transcriptional Activation; Transfection; Virus Replication; Zidovudine

2000
Primary macrophages infected by human immunodeficiency virus trigger CD95-mediated apoptosis of uninfected astrocytes.
    Journal of leukocyte biology, 2000, Volume: 68, Issue:3

    Topics: Anti-HIV Agents; Apoptosis; Astrocytes; Cell Communication; Cells, Cultured; Fas Ligand Protein; fas Receptor; Gene Products, tat; HIV; HIV Envelope Protein gp120; Homeostasis; Humans; Macrophages; Male; Membrane Glycoproteins; Middle Aged; Necrosis; tat Gene Products, Human Immunodeficiency Virus; Zidovudine

2000
PMS-601, a new platelet-activating factor receptor antagonist that inhibits human immunodeficiency virus replication and potentiates zidovudine activity in macrophages.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11

    Topics: Anti-HIV Agents; Drug Synergism; HIV; Humans; Macrophages; Piperazines; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Virus Replication; Zidovudine

2000
[Genotypic resistance to antiretroviral drugs in patients with therapeutic failure to highly active antiretroviral therapy].
    Medicina clinica, 2000, Oct-07, Volume: 115, Issue:11

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Microbial; Endopeptidases; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Male; Middle Aged; Mutation; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Treatment Failure; Zidovudine

2000
[Prevalence of primary mutations in human immunodeficiency virus with resistance to nucleoside analogues in previously untreated patients from Andalusia. Andalusian Group for the Study of Infectious diseases (GAEI)].
    Medicina clinica, 2000, Oct-07, Volume: 115, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4 Antigens; Codon; Data Interpretation, Statistical; DNA, Viral; Drug Resistance, Microbial; Female; Genotype; HIV; HIV Infections; Humans; Lamivudine; Male; Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Viral Load; Zidovudine

2000
[Resistance to antiretroviral drugs: a clinical, public health and health policy debate].
    Medicina clinica, 2000, Oct-07, Volume: 115, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Child; Clinical Trials as Topic; Drug Resistance, Microbial; Female; Genotype; Health Policy; HIV; HIV Infections; Humans; Male; Pregnancy; Public Health; Research; Reverse Transcriptase Inhibitors; Spain; Viral Load; Zidovudine

2000
Zidovudine phosphorylation determined sequentially over 12 months in human immunodeficiency virus-infected patients with or without previous exposure to antiretroviral agents.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3

    Topics: Adult; Anti-HIV Agents; Dideoxynucleotides; Female; HIV; HIV Infections; Humans; Longitudinal Studies; Male; Middle Aged; Phosphorylation; Thymine Nucleotides; Zidovudine

2001
Low-dose, sublingual AZT-monophosphate therapy for HIV+ patients?
    Medical hypotheses, 2001, Volume: 56, Issue:3

    Topics: Administration, Sublingual; Anti-HIV Agents; Dideoxynucleotides; HIV; HIV Infections; HIV Seropositivity; Humans; Models, Biological; Thymidine Kinase; Thymine Nucleotides; Virus Replication; Zidovudine

2001
ZDV resistance AIDS predictor.
    AIDS patient care, 1994, Volume: 8, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Drug Resistance; HIV; Humans; Zidovudine

1994
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Aug-04, Issue:no 228

    Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1995
A new nucleoside analogue.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Drugs, Investigational; HIV; Humans; Nucleosides; Phenotype; RNA-Directed DNA Polymerase; Zidovudine

1995
Saquinavir thwarts resistance.
    AIDS alert, 1995, Volume: 10, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Isoquinolines; Quinolines; Saquinavir; Zidovudine

1995
A Lisbon traviata. Are clinicians ready to sing addio to monotherapy and libiamo to combinations?
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Indinavir; Interleukin-2; Lamivudine; Mutation; Pyridines; RNA, Viral; Zalcitabine; Zidovudine

1995
Roaches of inner space.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Lamivudine; Mutation; T-Lymphocytes, Cytotoxic; Virulence; Virus Replication; Zalcitabine; Zidovudine

1995
Conference looks at HIV drug resistance.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:9

    Topics: Antiviral Agents; Carbamates; CD4 Lymphocyte Count; Drug Resistance, Microbial; Furans; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Sulfonamides; Thiazoles; Valine; Viremia; Zalcitabine; Zidovudine

1995
Mothers shown to transmit resistant strains to babies.
    AIDS alert, 1995, Volume: 10, Issue:11

    Topics: Antiviral Agents; HIV; HIV Infections; Infant, Newborn; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Viremia; Zidovudine

1995
Closing the circle on HIV--or not.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:9

    Topics: Antiviral Agents; Biomarkers; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-2; Nelfinavir; Prognosis; RNA, Viral; Zalcitabine; Zidovudine

1995
To treat or not to treat--approaches to antiretroviral therapy. Interview by Anthony J. Japour.
    AIDS clinical care, 1996, Volume: 8, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Didanosine; Drug Therapy, Combination; HIV; Humans; Lamivudine; Practice Patterns, Physicians'; RNA, Viral; Zalcitabine; Zidovudine

1996
Viral load linked to risk of transmission.
    AIDS alert, 1996, Volume: 11, Issue:5

    Topics: Female; HIV; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Risk Factors; RNA, Viral; Zidovudine

1996
Nipping HIV in the bud.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine

1996
Nevirapine: new drug, new class, new questions.
    Journal of the International Association of Physicians in AIDS Care, 1996, Volume: 2, Issue:7

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Approval; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

1996
Outdated yet out-of-reach: AIDS society treatment guidelines at the International Conference.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Decision Making; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Zalcitabine; Zidovudine

1996
Update on antivirals.
    PI perspective, 1996, Issue:No 19

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1996
NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases.
    NIAID AIDS agenda, 1997

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chemokines; Clinical Trials as Topic; Clone Cells; Dendritic Cells; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-10; Killer Cells, Natural; Lamivudine; Male; Nevirapine; Pyridines; Receptors, Cytokine; Reverse Transcriptase Inhibitors; Ritonavir; Virus Replication; Zalcitabine; Zidovudine

1997
New recommendations on health care worker exposure to HIV.
    STEP perspective, 1996,Fall, Volume: 8, Issue:3

    Topics: Anti-HIV Agents; Disease Transmission, Infectious; Drug Therapy, Combination; Guidelines as Topic; Health Personnel; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Risk Factors; Viral Load; Zidovudine

1996
Scientific basis for PEP rests in animal trials.
    AIDS alert, 1997, Volume: 12, Issue:9

    Topics: Adenine; Animals; Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Health Personnel; HIV; HIV Infections; Humans; Macaca; Nevirapine; Occupational Diseases; Organophosphonates; Organophosphorus Compounds; Pan troglodytes; Pyridines; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Tenofovir; United States; Zidovudine

1997
Hydroxyurea, a potential new anti-HIV agent.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:1

    Topics: Didanosine; DNA Replication; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Leukocytes, Mononuclear; Virus Replication; Zalcitabine; Zidovudine

1995
AIDS--the first 20 years.
    The New England journal of medicine, 2001, Jun-07, Volume: 344, Issue:23

    Topics: Acquired Immunodeficiency Syndrome; AIDS Vaccines; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood Banks; Female; Financing, Government; Global Health; History, 20th Century; History, 21st Century; HIV; HIV Seroprevalence; Humans; Male; Research Support as Topic; United States; Zidovudine

2001
Prevalence and predictive value of intermittent viremia with combination hiv therapy.
    JAMA, 2001, Jul-11, Volume: 286, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Predictive Value of Tests; Prevalence; Proportional Hazards Models; Retrospective Studies; RNA, Viral; Viral Load; Viremia; Virus Replication; Zidovudine

2001
Inhibition of HIV replication by A77 1726, the active metabolite of leflunomide, in combination with pyrimidine nucleoside reverse transcriptase inhibitors.
    Journal of acquired immune deficiency syndromes (1999), 2001, Oct-01, Volume: 28, Issue:2

    Topics: Aniline Compounds; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Crotonates; HIV; HIV Core Protein p24; HIV Seronegativity; Humans; Hydroxybutyrates; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphocytes; Nitriles; Reverse Transcriptase Inhibitors; Toluidines; Virus Replication; Zidovudine

2001
HIV pathogenesis and activation of CD4 cells.
    AIDS clinical care, 2001, Volume: 13, Issue:10

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Genes, nef; Genes, tat; HIV; Humans; Interleukin-2; Lymphocyte Activation; Reverse Transcriptase Inhibitors; Up-Regulation; Virus Replication; Zidovudine

2001
Zidovudine (Retrovir).
    Research initiative, treatment action : RITA, 2000, Volume: 6, Issue:1

    Topics: Drug Resistance, Microbial; HIV; HIV Infections; Humans; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Zidovudine

2000
Experience with routine voluntary perinatal human immunodeficiency virus testing in an inner city hospital.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11

    Topics: Anti-HIV Agents; Decision Making; Female; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Logistic Models; Mass Screening; Pregnancy; Prenatal Care; Risk Factors; Zidovudine

2001
Prediction of abacavir resistance from genotypic data: impact of zidovudine and lamivudine resistance in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1

    Topics: Algorithms; Anti-HIV Agents; Dideoxynucleosides; Drug Resistance, Microbial; Gene Frequency; Genotype; HIV; Humans; Lamivudine; Microbial Sensitivity Tests; Zidovudine

2002
Estimation of the timing of perinatal transmission of HIV.
    Biometrics, 2001, Volume: 57, Issue:4

    Topics: Anti-HIV Agents; Biometry; Clinical Trials as Topic; Female; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Linear Models; Models, Statistical; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Sensitivity and Specificity; Time Factors; Zidovudine

2001
An APE that proofreads.
    Nature, 2002, Feb-07, Volume: 415, Issue:6872

    Topics: Anti-HIV Agents; Carbon-Oxygen Lyases; DNA; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Viral; Escherichia coli; HIV; Humans; Stavudine; Substrate Specificity; Zidovudine

2002
Transmission of drug-resistant HIV after an occupational exposure despite postexposure prophylaxis with a combination drug regimen.
    Infection control and hospital epidemiology, 2002, Volume: 23, Issue:6

    Topics: Adult; Anti-HIV Agents; Health Personnel; HIV; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Needlestick Injuries; Occupational Exposure; Treatment Failure; Zidovudine

2002
Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Antiviral Agents; Emtricitabine; HIV; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine; Zidovudine

1992
Pharmacokinetic evaluation of drug interactions with anti-human immunotrophic virus (HIV) Drugs. III. 2',3'-Dideoxycytidine (ddC) and zidovudine in monkeys.
    Pharmaceutical research, 1992, Volume: 9, Issue:2

    Topics: Animals; Antiviral Agents; Drug Interactions; HIV; Macaca fascicularis; Male; Zalcitabine; Zidovudine

1992
The defect seen in the phosphatidylinositol hydrolysis pathway in HIV-infected lymphocytes and lymphoblastoid cells is due to inhibition of the inositol 1,4,5-trisphosphate 1,3,4,5-tetrakisphosphate 5-phosphomonoesterase.
    Clinical and experimental immunology, 1992, Volume: 89, Issue:1

    Topics: Adenosine Triphosphate; Calcium; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Down-Regulation; HIV; HIV Envelope Protein gp120; Humans; Hydrolysis; Inositol Polyphosphate 5-Phosphatases; Lymphocytes; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Signal Transduction; Zidovudine

1992
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.
    Antiviral research, 1992, Volume: 17, Issue:4

    Topics: Adenine; Antibodies, Viral; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cytokines; Didanosine; Doxorubicin; Drug Interactions; HIV; HIV Infections; Humans; Imidazoles; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Monocytes; Organ Specificity; Organophosphonates; Zalcitabine; Zidovudine

1992
Inhibition of HIV infection of resting peripheral blood lymphocytes by nucleosides.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:7

    Topics: Base Sequence; Cells, Cultured; Didanosine; DNA, Viral; HIV; Humans; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; Proviruses; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine

1992
Anti-human immunodeficiency virus (HIV) agents are also potent and selective inhibitors of feline immunodeficiency virus (FIV)-induced cytopathic effect: development of a new method for screening of anti-FIV substances in vitro.
    Antiviral research, 1992, Volume: 19, Issue:2

    Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Antiviral Agents; Cats; Cell Fusion; Cells, Cultured; Cytopathogenic Effect, Viral; Dextran Sulfate; Didanosine; Drug Evaluation, Preclinical; Heparin; HIV; Humans; Immunodeficiency Virus, Feline; Virus Replication; Zidovudine

1992
HIV as target for zidovudine.
    Lancet (London, England), 1992, Feb-29, Volume: 339, Issue:8792

    Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Zidovudine

1992
HIV and AIDS.
    The Medical journal of Australia, 1992, Jul-20, Volume: 157, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; Female; HIV; HIV Infections; Humans; Male; Research; Viral Vaccines; Zidovudine

1992
[Another AIDS drug. Azidothymidine--dideoxycytidine].
    Fortschritte der Medizin, 1992, Jun-30, Volume: 110, Issue:18

    Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; HIV; Humans; Leukocyte Count; Virus Replication; Zalcitabine; Zidovudine

1992
Development of resistance to zidovudine in HIV strains isolated from CD4+ lymphocytes and plasma during therapy.
    Antiviral research, 1992, Volume: 18, Issue:3-4

    Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; Drug Resistance, Microbial; HIV; Humans; Zidovudine

1992
Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects.
    The Journal of infectious diseases, 1992, Volume: 165, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Codon; Cohort Studies; Drug Resistance, Microbial; Genotype; HeLa Cells; HIV; HIV Infections; Homosexuality; Humans; Male; Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Time Factors; Viral Plaque Assay; Zidovudine

1992
Selective action of 2',3'-didehydro-2',3'-dideoxythymidine triphosphate on human immunodeficiency virus reverse transcriptase and human DNA polymerases.
    The Journal of biological chemistry, 1992, Feb-05, Volume: 267, Issue:4

    Topics: Antiviral Agents; Base Sequence; DNA; DNA-Directed DNA Polymerase; HIV; Humans; Kinetics; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Substrate Specificity; Thymine Nucleotides; Zidovudine

1992
Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation.
    Biochemistry, 1992, May-12, Volume: 31, Issue:18

    Topics: Antiviral Agents; Base Sequence; Binding, Competitive; Dideoxynucleotides; HIV; Molecular Sequence Data; Oligonucleotide Probes; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Templates, Genetic; Thionucleotides; Thymine Nucleotides; Zidovudine

1992
Biochemical studies on the reverse transcriptase and RNase H activities from human immunodeficiency virus strains resistant to 3'-azido-3'-deoxythymidine.
    The Journal of biological chemistry, 1992, Aug-05, Volume: 267, Issue:22

    Topics: Antiviral Agents; Cell Line; Drug Resistance, Microbial; HIV; Humans; Kinetics; Polynucleotides; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA-Directed DNA Polymerase; Species Specificity; Substrate Specificity; Zidovudine

1992
Effects of bone marrow stimulatory cytokines on human immunodeficiency virus replication and the antiviral activity of dideoxynucleosides in cultures of monocyte/macrophages.
    Blood, 1992, Aug-15, Volume: 80, Issue:4

    Topics: Antiviral Agents; Bone Marrow; Cells, Cultured; Cytokines; Didanosine; Dideoxynucleosides; Erythropoietin; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Virus Replication; Zalcitabine; Zidovudine

1992
Gastrointestinal tissue cultures for HIV in HIV-infected/AIDS patients. The University of Calgary Gastrointestinal/HIV Study Group.
    AIDS (London, England), 1992, Volume: 6, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Bisexuality; Digestive System; Duodenum; Esophagus; HIV; HIV Infections; Homosexuality; Humans; Male; Rectum; Stomach; Zidovudine

1992
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA.
    The Journal of biological chemistry, 1992, Oct-25, Volume: 267, Issue:30

    Topics: Antiviral Agents; Base Sequence; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase I; DNA Polymerase II; HIV; Humans; Kinetics; Molecular Sequence Data; Terminator Regions, Genetic; Thymine Nucleotides; Zidovudine

1992
Incidence of zidovudine-resistant human immunodeficiency virus isolated from patients before, during, and after therapy.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:5

    Topics: CD4 Antigens; Drug Resistance, Microbial; Female; Hemophilia A; HIV; HIV Antigens; HIV Infections; Homosexuality; Humans; Male; Substance Abuse, Intravenous; T-Lymphocyte Subsets; Virus Replication; Zidovudine

1992
Summary of the Working Group on Perinatal Intervention.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:8

    Topics: Animals; Clinical Trials as Topic; Female; Fetal Diseases; HIV; HIV Infections; Humans; Immunization, Passive; Immunoglobulins, Intravenous; Infant; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Vaccination; Zidovudine

1992
Quantitative RNA and DNA gene amplification can rapidly monitor HIV infection and antiviral activity in cell cultures.
    PCR methods and applications, 1992, Volume: 1, Issue:4

    Topics: Cells, Cultured; DNA, Viral; Genes, gag; HIV; HIV Core Protein p24; HIV Infections; HIV Seropositivity; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; RNA, Viral; Virus Replication; Zidovudine

1992
A modeled time-varying density function for the incubation period of AIDS.
    Journal of mathematical biology, 1992, Volume: 31, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; HIV; HIV Infections; Humans; Mathematics; Proportional Hazards Models; Time Factors; Zidovudine

1992
Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:4

    Topics: Animals; Antiviral Agents; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Dideoxynucleosides; Female; HIV; Humans; Macaca fascicularis; Male; Tritium; Zidovudine

1992
HIV detection in culture of peripheral blood mononuclear cells: a relevant in vitro correlate of the antiviral effect of ZDV in vivo.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5, Issue:8

    Topics: Cells, Cultured; Female; HIV; HIV Seropositivity; Humans; Leukocytes, Mononuclear; Male; Virus Replication; Zidovudine

1992
The effect of combinations of ampligen and zidovudine or dideoxyinosine against human immunodeficiency viruses in vitro.
    Antiviral research, 1992, Volume: 17, Issue:2

    Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Didanosine; Drug Synergism; HeLa Cells; HIV; Humans; Poly I-C; Poly U; Zidovudine

1992
Synthesis and anti-HIV activity of some novel lactyl and glycolyl phosphate derivatives.
    Antiviral research, 1992, Volume: 17, Issue:3

    Topics: Antiviral Agents; HIV; Organophosphorus Compounds; Zidovudine

1992
Rage and confusion hide role of HIV.
    Nature, 1992, May-21, Volume: 357, Issue:6375

    Topics: Acquired Immunodeficiency Syndrome; Complementary Therapies; HIV; HIV Infections; Humans; Zidovudine

1992
Synergistic antiviral effect in vitro of azidothymidine and amphotericin B methyl ester in combination on HIV infection.
    Scandinavian journal of infectious diseases, 1992, Volume: 24, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Cells, Cultured; Drug Synergism; Drug Therapy, Combination; HIV; HIV Infections; Humans; Zidovudine

1992
Lipid conjugates of antiretroviral agents: release of antiretroviral nucleoside monophosphates by a nucleoside diphosphate diglyceride hydrolase activity from rat liver mitochondria.
    Biochimica et biophysica acta, 1991, Jul-30, Volume: 1084, Issue:3

    Topics: Animals; Antiviral Agents; Cardiolipins; Diglycerides; HIV; Hydrolysis; Lipid Metabolism; Mitochondria, Liver; Phosphorylation; Pyrophosphatases; Rats; Thymine Nucleotides; Zidovudine

1991
Markers for HIV-disease progression in untreated patients and patients receiving AZT: evaluation of viral activity, AZT resistance, serum cholesterol, beta 2-microglobulin, CD4+ cell counts, and HIV antigen.
    Infection, 1991, Volume: 19 Suppl 2

    Topics: beta 2-Microglobulin; CD4-Positive T-Lymphocytes; Cells, Cultured; Cholesterol, HDL; Drug Resistance, Microbial; Evaluation Studies as Topic; HIV; HIV Antigens; HIV Infections; Humans; Leukocyte Count; Macrophages; Monocytes; Time Factors; Zidovudine

1991
Carbovir: the (-) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro.
    Antiviral research, 1991, Volume: 15, Issue:2

    Topics: CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Dideoxynucleosides; Giant Cells; HIV; Humans; Viral Core Proteins; Virus Replication; Zalcitabine; Zidovudine

1991
Reduction in plasma human immunodeficiency virus ribonucleic acid after dideoxynucleoside therapy as determined by the polymerase chain reaction.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:5

    Topics: CD4-Positive T-Lymphocytes; HIV; HIV Seropositivity; Humans; Leukocyte Count; Polymerase Chain Reaction; RNA, Viral; Zidovudine

1991
Anti-HIV agents. I: Synthesis and in vitro anti-HIV evaluation of novel 1H,3H-thiazolo[3,4-a]benzimidazoles.
    Farmaco (Societa chimica italiana : 1989), 1991, Volume: 46, Issue:6

    Topics: Antiviral Agents; Benzimidazoles; CD4-Positive T-Lymphocytes; Cell Line; Cytopathogenic Effect, Viral; HIV; Humans; Thiazoles; Zalcitabine; Zidovudine

1991
Pharmacokinetics of anti-HIV nucleosides in microswine.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:12

    Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Didanosine; Half-Life; HIV; Male; Nucleosides; Swine; Swine, Miniature; Zalcitabine; Zidovudine

1991
Mechanism of HIV reverse transcriptase: enzyme-primer interaction as revealed through studies of a dNTP analogue, 3'-azido-dTTP.
    Biochemistry, 1990, Apr-17, Volume: 29, Issue:15

    Topics: Antiviral Agents; Bacteriophages; Chemical Phenomena; Chemistry; Dideoxynucleotides; DNA; DNA-Directed DNA Polymerase; HIV; Kinetics; Models, Molecular; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides; Zidovudine

1990
Selective action of 3'-azido-3'-deoxythymidine 5'-triphosphate on viral reverse transcriptases and human DNA polymerases.
    The Journal of biological chemistry, 1990, Jul-15, Volume: 265, Issue:20

    Topics: Antiviral Agents; Avian Myeloblastosis Virus; Base Sequence; Cell Line; Dideoxynucleotides; DNA Polymerase II; DNA Polymerase III; DNA-Directed DNA Polymerase; HIV; Humans; Molecular Sequence Data; Moloney murine leukemia virus; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Probes; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymine Nucleotides; Zidovudine

1990
[Comparative inhibitory analysis of DNA biosynthesis catalyzed by retrovirus reverse transcriptase].
    Bioorganicheskaia khimiia, 1990, Volume: 16, Issue:4

    Topics: Avian Myeloblastosis Virus; Avian Sarcoma Viruses; Catalysis; Chemical Phenomena; Chemistry; DNA; HIV; Oligodeoxyribonucleotides; Poly A; Retroviridae; Reverse Transcriptase Inhibitors; Templates, Genetic; Zidovudine

1990
Export and one-step purification from Escherichia coli of a MalE-CD4 hybrid protein that neutralizes HIV in vitro.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3, Issue:9

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; ATP-Binding Cassette Transporters; Base Sequence; Blotting, Western; Carrier Proteins; CD4 Antigens; Chromatography, Affinity; Cloning, Molecular; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Gene Expression; HIV; In Vitro Techniques; Maltose-Binding Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Peptide Mapping; Periplasmic Binding Proteins; Plasmids; Recombinant Fusion Proteins; RNA-Directed DNA Polymerase; Zidovudine

1990
Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:22

    Topics: ADP Ribose Transferases; Bacterial Toxins; CD4 Antigens; Cells, Cultured; Didanosine; Drug Synergism; Exotoxins; HIV; HIV Infections; Humans; Immunotoxins; In Vitro Techniques; Pseudomonas aeruginosa Exotoxin A; Reverse Transcriptase Inhibitors; T-Lymphocytes; Virulence Factors; Virus Replication; Zidovudine

1990
Antileukemic activity of Viva-Natural, a dietary seaweed extract, on Rauscher murine leukemia in comparison with anti-HIV agents, azidothymidine, dextran sulfate and pentosan polysulfate.
    Cancer letters, 1991, Volume: 56, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line; Dextran Sulfate; Female; HIV; Leukemia, Experimental; Male; Mice; Mice, Inbred BALB C; Pentosan Sulfuric Polyester; Plant Extracts; Rauscher Virus; Seaweed; Splenomegaly; Zidovudine

1991
Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:2

    Topics: Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Cell Division; Colony-Forming Units Assay; Didanosine; Drug Synergism; Erythroid Precursor Cells; HIV; Humans; In Vitro Techniques; RNA-Directed DNA Polymerase; Stem Cells; Zidovudine

1991
Combined therapy with recombinant granulocyte colony-stimulating factor and erythropoietin decreases hematologic toxicity from zidovudine.
    Blood, 1991, May-15, Volume: 77, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Blood Cell Count; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Erythropoietin; Ganciclovir; Gene Products, gag; Granulocyte Colony-Stimulating Factor; Hemoglobins; HIV; HIV Core Protein p24; Humans; Injections, Subcutaneous; Neutropenia; Opportunistic Infections; Recombinant Proteins; Viral Core Proteins; Virus Replication; Zidovudine

1991
Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes.
    AIDS (London, England), 1991, Volume: 5, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Base Sequence; Cell Line; Cloning, Molecular; DNA, Viral; Drug Resistance, Microbial; HeLa Cells; HIV; Humans; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; T-Lymphocytes; Zidovudine

1991
Inhibition of the RNase H activity of HIV reverse transcriptase by azidothymidylate.
    Biochemistry, 1991, May-21, Volume: 30, Issue:20

    Topics: Antiviral Agents; Cloning, Molecular; Deoxyribonucleotides; Dideoxynucleotides; Endoribonucleases; Escherichia coli; HIV; Kinetics; Nucleic Acid Synthesis Inhibitors; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribonuclease H; Ribonucleotides; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1991
Phosphatidylazidothymidine. Mechanism of antiretroviral action in CEM cells.
    The Journal of biological chemistry, 1991, Jun-25, Volume: 266, Issue:18

    Topics: Cell Line; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glycerophospholipids; HIV; Phosphatidic Acids; Retroviridae; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine

1991
The characterization of EIAV reverse transcriptase and its inhibition by 5'-triphosphates of 2'-deoxyuridine analogs, PFA and PAA.
    Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1990, Volume: 5, Issue:3

    Topics: Antiviral Agents; Dideoxynucleotides; Foscarnet; HIV; Infectious Anemia Virus, Equine; Phosphonoacetic Acid; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1990
Synergistic combinations and peptides in the inhibition of human immunodeficiency virus.
    Advances in enzyme regulation, 1991, Volume: 31

    Topics: Alpha-Globulins; Amino Acid Sequence; Antiviral Agents; Cell Line; Dideoxynucleosides; Drug Synergism; Foscarnet; HIV; Humans; Molecular Sequence Data; Oligopeptides; Phosphonoacetic Acid; Proteins; Reverse Transcriptase Inhibitors; Serine Proteinase Inhibitors; Virus Replication; Zidovudine

1991
Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture.
    Journal of virology, 1991, Volume: 65, Issue:10

    Topics: Base Sequence; Cell Line; Cloning, Molecular; Codon; Drug Resistance, Microbial; Escherichia coli; HIV; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Viral Plaque Assay; Zidovudine

1991
Potential use of human stem cell factor as adjunctive therapy for human immunodeficiency virus-related cytopenias.
    Blood, 1991, Dec-15, Volume: 78, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Anemia; Colony-Forming Units Assay; Erythroid Precursor Cells; Erythropoietin; Granulocytes; Hematopoietic Cell Growth Factors; HIV; HIV Infections; Humans; Lymphocytes; Macrophages; Monocytes; Neutropenia; Recombinant Proteins; Stem Cell Factor; Thrombocytopenia; Virus Replication; Zidovudine

1991
Alpha-lipoic acid is an effective inhibitor of human immuno-deficiency virus (HIV-1) replication.
    Klinische Wochenschrift, 1991, Oct-02, Volume: 69, Issue:15

    Topics: Cells, Cultured; Cytopathogenic Effect, Viral; HIV; HIV Reverse Transcriptase; HIV-1; RNA-Directed DNA Polymerase; T-Lymphocytes; Thioctic Acid; Viral Plaque Assay; Virus Replication; Zidovudine

1991
Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus.
    The Journal of biological chemistry, 1992, Jan-05, Volume: 267, Issue:1

    Topics: Cell Line; DNA; HIV; Humans; Kinetics; Phosphorylation; Substrate Specificity; T-Lymphocytes; Thymidine; Thymidine Kinase; Thymidine Phosphorylase; Virus Replication; Zidovudine

1992
Plasma viremia in human immunodeficiency virus infection: relationship to stage of disease and antiviral treatment.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5, Issue:2

    Topics: AIDS-Related Complex; Chi-Square Distribution; HIV; HIV Core Protein p24; HIV Infections; Humans; Regression Analysis; Sensitivity and Specificity; Viremia; Virus Cultivation; Zidovudine

1992
Enhancement of HIV-specific cytotoxic T lymphocyte responses by zidovudine (AZT) treatment.
    Clinical and experimental immunology, 1992, Volume: 87, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; Follow-Up Studies; HIV; Humans; T-Lymphocytes, Cytotoxic; Zidovudine

1992
Decrease in HIV provirus in peripheral blood mononuclear cells during zidovudine and human rIL-2 administration.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5, Issue:1

    Topics: DNA, Viral; Follow-Up Studies; HIV; HIV Infections; HIV Seropositivity; Humans; Interleukin-2; Leukocytes, Mononuclear; Polymerase Chain Reaction; Proviruses; Recombinant Proteins; Zidovudine

1992
Synthesis of 1-(3-azido-2,3-dideoxy-beta-D-allofuranosyl)thymine, 1-(2,3-dideoxy-beta-D-allofuranosyl)thymine, and 1-(2,3-dideoxy-beta-D-erythro-hex-2-enofuranosyl)thymine.
    Carbohydrate research, 1991, Sep-02, Volume: 216

    Topics: Antiviral Agents; Dideoxynucleosides; HIV; Molecular Structure; Zidovudine

1991
A new method of synthesis of 3'-mercapto-3'-deoxythymidine.
    Nucleic acids symposium series, 1991, Issue:24

    Topics: Antiviral Agents; Cell Line; HIV; Humans; T-Lymphocytes; Thymidine; Zidovudine

1991
Mechanisms of inhibitions of DNA polymerase gamma by nucleotide analogues having anti-HIV activities.
    Nucleic acids symposium series, 1991, Issue:25

    Topics: Animals; Antiviral Agents; Cattle; Dideoxynucleotides; DNA Polymerase III; HIV; Male; Thymine Nucleotides; Zidovudine

1991
[AIDS: initial results of combination therapy. AIDS and ARC--alternating or intermittent medication].
    Fortschritte der Medizin, 1991, Jan-15, Volume: 109, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4 Antigens; Combined Modality Therapy; HIV; Humans; Immunotherapy, Adoptive; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine

1991
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
    Molecular pharmacology, 1991, Volume: 39, Issue:5

    Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine

1991
Acquired immunodeficiency syndrome. Cerebrospinal fluid findings in patients before and during long-term oral zidovudine therapy.
    Archives of neurology, 1991, Volume: 48, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Cerebrospinal Fluid; Female; HIV; Humans; Male; Middle Aged; Zidovudine

1991
Fertility parameters in men infected with human immunodeficiency virus.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Fertility; HIV; HIV Infections; HIV Seropositivity; Humans; Male; Semen; Sperm Count; Spermatozoa; Zidovudine

1991
Human immunodeficiency virus (HIV)-infected tumor xenografts as an in vivo model for antiviral therapy: role of alpha/beta interferon in restriction of tumor growth in nude mice injected with HIV-infected U937 tumor cells.
    Journal of virology, 1991, Volume: 65, Issue:5

    Topics: Animals; Antibodies; Cell Division; Disease Models, Animal; Female; Gene Products, gag; HIV; HIV Antigens; HIV Core Protein p24; HIV Infections; Humans; Immunosuppression Therapy; Interferon Type I; Lymphoma; Male; Mice; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Viral Core Proteins; Virus Replication; Zidovudine

1991
Human immunodeficiency virus infection of human lymph nodes in the SCID-hu mouse.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, May-15, Volume: 88, Issue:10

    Topics: Animals; Antiviral Agents; Didanosine; DNA, Viral; HIV; HIV Infections; Humans; Immunohistochemistry; Immunologic Deficiency Syndromes; Lymph Nodes; Macrophages; Mice; Nucleic Acid Hybridization; Polymerase Chain Reaction; T-Lymphocytes; Transplantation, Heterologous; Zidovudine

1991
Modeling zidovudine therapy: a cost-effectiveness analysis.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Cost-Benefit Analysis; HIV; Humans; Male; Models, Theoretical; Sensitivity and Specificity; Time Factors; United States; Zidovudine

1991
[Antiretroviral therapy in Switzerland 1991].
    Schweizerische medizinische Wochenschrift, 1991, Aug-24, Volume: 121, Issue:34

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV; Humans; RNA, Viral; Virus Replication; Zidovudine

1991
Biochemical and genetical analysis of AZT-resistant HIV-mutants.
    Behring Institute Mitteilungen, 1991, Issue:89

    Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Cloning, Molecular; DNA, Viral; Drug Resistance, Microbial; HIV; Humans; Monocytes; Polymerase Chain Reaction; Virus Replication; Zidovudine

1991
Zidovudine after occupational exposure to HIV.
    BMJ (Clinical research ed.), 1991, Oct-19, Volume: 303, Issue:6808

    Topics: HIV; HIV Infections; Humans; Occupational Diseases; Occupational Exposure; Zidovudine

1991
Synthesis and biological evaluation of dinucleoside methylphosphonates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxycytidine.
    Antiviral research, 1990, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Deoxycytosine Nucleotides; Drug Evaluation, Preclinical; HIV; Hydrolysis; Mice; Mice, Inbred C3H; Moloney murine sarcoma virus; Thymine Nucleotides; Tumor Cells, Cultured; Virus Replication; Zalcitabine; Zidovudine

1990
AIDS meeting: unexpected progress.
    Science (New York, N.Y.), 1990, Jun-29, Volume: 248, Issue:4963

    Topics: Acquired Immunodeficiency Syndrome; Congresses as Topic; HIV; San Francisco; Zidovudine

1990
Hybrid pharmacokinetic models to describe anti-HIV nucleoside brain disposition following parent and prodrug administration in mice.
    Pharmaceutical research, 1991, Volume: 8, Issue:2

    Topics: Animals; Antiviral Agents; Brain; Dihydropyridines; Female; HIV; Mice; Models, Biological; Nucleosides; Prodrugs; Zidovudine

1991
Characterization of genetic variation and 3'-azido-3'-deoxythymidine- resistance mutations of human immunodeficiency virus by the RNase A mismatch cleavage method.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, May-15, Volume: 88, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Base Sequence; Codon; DNA, Viral; Drug Resistance, Microbial; Genes, Viral; Genetic Variation; HIV; HIV Envelope Protein gp120; Humans; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Polymerase Chain Reaction; Ribonuclease, Pancreatic; Viral Proteins; Zidovudine

1991
Programmed activation of T-lymphocytes. A theoretical basis for short term treatment of AIDS with azidothymidine.
    Medical hypotheses, 1991, Volume: 34, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; DNA, Viral; HIV; Humans; Lymphocyte Activation; T-Lymphocytes; Virus Replication; Zidovudine

1991
Use of a focal infectivity assay for testing susceptibility of HIV to antiviral agents.
    BioTechniques, 1991, Volume: 10, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Gene Products, env; HeLa Cells; HIV; HIV Antibodies; HIV Envelope Protein gp120; HIV Envelope Protein gp160; Humans; Immunoenzyme Techniques; Immunoglobulin G; Immunotoxins; Interferon Type I; Protein Precursors; Recombinant Proteins; Ricin; Zidovudine

1991
In vivo prevalence of azidothymidine (AZT) resistance mutations in an AIDS patient before and after AZT therapy.
    AIDS research and human retroviruses, 1991, Volume: 7, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amino Acid Sequence; Base Sequence; DNA, Viral; Drug Resistance, Microbial; Genes, pol; HIV; Humans; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Sequence Alignment; Time Factors; Zidovudine

1991
[AIDS: the outlook from 1991].
    Le Chirurgien-dentiste de France, 1991, Apr-11, Volume: 61, Issue:560

    Topics: Acquired Immunodeficiency Syndrome; CD4 Antigens; HIV; Humans; T-Lymphocytes; Viral Vaccines; Zidovudine

1991
Synthesis and anti-HIV evaluation of some phosphoramidate derivatives of AZT: studies on the effect of chain elongation on biological activity.
    Antiviral research, 1990, Volume: 14, Issue:6

    Topics: Cells, Cultured; Deoxyribonucleotides; DNA; Dose-Response Relationship, Drug; HIV; HIV Infections; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Prodrugs; Structure-Activity Relationship; Thymine Nucleotides; Zidovudine

1990
2'-Azido-2',3'-dideoxythymidine: synthesis and crystal structure of a 2'-substituted dideoxynucleoside.
    Antiviral research, 1990, Volume: 14, Issue:6

    Topics: Antiviral Agents; Crystallography; Dideoxynucleosides; HIV; Humans; In Vitro Techniques; Molecular Structure; Structure-Activity Relationship; Virus Replication; X-Ray Diffraction; Zidovudine

1990
Activation of a beta-galactosidase recombinant provirus: application to titration of human immunodeficiency virus (HIV) and HIV-infected cells.
    Journal of virology, 1990, Volume: 64, Issue:6

    Topics: beta-Galactosidase; Blotting, Southern; Cell Line; Clone Cells; Galactosidases; HIV; HIV-1; Humans; Kinetics; Lymphocytes; Plasmids; Proviruses; Restriction Mapping; RNA, Viral; Simian Immunodeficiency Virus; Transcriptional Activation; Transfection; Virus Activation; Zidovudine

1990
Effect of stage of disease and drug dose on zidovudine susceptibilities of isolates of human immunodeficiency virus.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4 Antigens; Gene Products, gag; HIV; HIV Core Protein p24; Humans; Leukocyte Count; Microbial Sensitivity Tests; Time Factors; Viral Core Proteins; Zidovudine

1990
Clinical response to dideoxyinosine in patients with HIV infection resistant to zidovudine.
    The New England journal of medicine, 1990, Jul-26, Volume: 323, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Resistance, Microbial; HIV; Humans; Zidovudine

1990
[Virological monitoring in subjects with HIV infection under treatment with zidovudine (AZT)].
    Bollettino della Societa italiana di biologia sperimentale, 1990, Volume: 66, Issue:6

    Topics: Gene Products, gag; HIV; HIV Core Protein p24; HIV Infections; Humans; Viral Core Proteins; Viremia; Virus Replication; Zidovudine

1990
Suppression of feline immunodeficiency virus infection in vivo by 9-(2-phosphonomethoxyethyl)adenine.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:8

    Topics: Adenine; Animals; Antiviral Agents; Cats; Cell Line; HIV; Immunologic Deficiency Syndromes; Opportunistic Infections; Organophosphonates; Retroviridae; Retroviridae Infections; T-Lymphocytes; Virus Replication; Zidovudine

1990
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine

1990
Vesicular changes in the myopathies of AIDS. Ultrastructural observations and their relationship to zidovudine treatment.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Cytopathogenic Effect, Viral; Cytoplasm; HIV; Humans; Inclusion Bodies; Male; Microscopy, Electron; Middle Aged; Muscles; Muscular Atrophy; Myofibrils; Necrosis; Sarcoplasmic Reticulum; Zidovudine

1990
Strategies for the combination therapy of HIV infection.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3 Suppl 2

    Topics: Acyclovir; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; Humans; Virus Replication; Zalcitabine; Zidovudine

1990
Oral melanotic macules in patients infected with human immunodeficiency virus.
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 70, Issue:6

    Topics: Adult; Chi-Square Distribution; DNA, Viral; Female; Herpesvirus 4, Human; HIV; HIV Infections; Humans; Lip Diseases; Male; Melanosis; Middle Aged; Mouth Diseases; Mouth Mucosa; Nucleic Acid Hybridization; Zidovudine

1990
Potential anti-HIV active pyranoid analogs of AZT.
    Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1990, Volume: 44, Issue:3

    Topics: Antiviral Agents; HIV; Magnetic Resonance Spectroscopy; Zidovudine

1990
Induction of monocyte proliferation and HIV expression by IL-3 does not interfere with anti-viral activity of zidovudine.
    Blood, 1990, Oct-15, Volume: 76, Issue:8

    Topics: Cell Division; Cells, Cultured; HIV; Humans; Interleukin-3; Monocytes; Virus Replication; Zidovudine

1990
Cellular metabolism of 3'-azido-2',3'-dideoxyuridine with formation of 5'-O-diphosphohexose derivatives by previously unrecognized metabolic pathways for 2'-deoxyuridine analogs.
    Molecular pharmacology, 1990, Volume: 38, Issue:6

    Topics: Antiviral Agents; Bone Marrow; Chromatography, High Pressure Liquid; Dideoxynucleotides; HIV; Humans; Leukocytes, Mononuclear; Thymine Nucleotides; Zidovudine

1990
Benzylacyclouridine reverses azidothymidine-induced marrow suppression without impairment of anti-human immunodeficiency virus activity.
    Blood, 1990, Dec-01, Volume: 76, Issue:11

    Topics: Anemia; Animals; Cell Line; Cytopathogenic Effect, Viral; Female; HIV; Leukopenia; Mice; Mice, Inbred BALB C; Uracil; Uridine; Zidovudine

1990
Interactive laser cytometric analysis of retroviral protein expression in HIV-infected lymphocytic cell lines.
    AIDS research and human retroviruses, 1990, Volume: 6, Issue:9

    Topics: Cell Line; Fluorescent Antibody Technique; HIV; HIV Antigens; Humans; Kinetics; Lasers; Microscopy, Fluorescence; Viral Envelope Proteins; Zidovudine

1990
Progress in targeted therapy against human immunodeficiency virus [corrected].
    Critical care medicine, 1990, Volume: 18, Issue:2 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Cytopathogenic Effect, Viral; Dideoxynucleosides; DNA, Viral; Genes, Viral; HIV; Humans; Protein Biosynthesis; Receptors, Antigen, T-Cell; RNA, Viral; Viral Envelope Proteins; Virus Replication; Zidovudine

1990
Decreased in vitro susceptibility to zidovudine of HIV isolates obtained from patients with AIDS.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Cell Line; Cytopathogenic Effect, Viral; HIV; Humans; Microbial Sensitivity Tests; Virus Replication; Zidovudine

1990
Suppression of HIV infection in AZT-treated SCID-hu mice.
    Science (New York, N.Y.), 1990, Feb-02, Volume: 247, Issue:4942

    Topics: Animals; DNA, Viral; HIV; HIV Infections; Humans; Mice; Mice, Mutant Strains; Nucleic Acid Hybridization; Polymerase Chain Reaction; Spleen; Thymus Gland; Transplantation, Heterologous; Zidovudine

1990
HIV eliminated in AIDS patient with lymphoma.
    American family physician, 1990, Volume: 41, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Bone Marrow Transplantation; Combined Modality Therapy; HIV; Hodgkin Disease; Male; Zidovudine

1990
Synthesis and antiretroviral activity of phospholipid analogs of azidothymidine and other antiviral nucleosides.
    The Journal of biological chemistry, 1990, Apr-15, Volume: 265, Issue:11

    Topics: Antiviral Agents; Cell Line; HIV; Humans; Indicators and Reagents; Liposomes; Magnetic Resonance Spectroscopy; Nucleosides; Phospholipids; Structure-Activity Relationship; Virus Replication; Zidovudine

1990
2'-azido-2',3'-dideoxypyrimidine nucleosides. Synthesis and antiviral activity against human immunodeficiency virus.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: Antiviral Agents; HIV; Humans; Zidovudine

1990
[HIV infection in adults and children. Approaches to therapy. Position of the scientific consultant of the federal medical council].
    Medizinische Monatsschrift fur Pharmazeuten, 1990, Volume: 13, Issue:5

    Topics: Adult; Child; Germany, West; HIV; HIV Infections; Humans; Zidovudine

1990
Synthesis of 1-methyl-5-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)uracil and 1-methyl-5-(3-azido-2,3-dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil. The C-nucleoside isostere of 3'-azido-3'-deoxythymidine and its 2'-"up"-fluoro analogue.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Antiviral Agents; Cell Line; HIV; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Zidovudine

1990
Activities of (-)-carbovir and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6

    Topics: Antiviral Agents; Cell Line; Cell Survival; Dideoxynucleosides; HIV; Humans; Virus Replication; Zidovudine

1990
Lipid conjugates of antiretroviral agents. I. Azidothymidine-monophosphate-diglyceride: anti-HIV activity, physical properties, and interaction with plasma proteins.
    Biochemical and biophysical research communications, 1990, Aug-31, Volume: 171, Issue:1

    Topics: Antiviral Agents; Blood Proteins; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Diglycerides; Dose-Response Relationship, Drug; Glycerides; HIV; Humans; In Vitro Techniques; Liposomes; Retroviridae Proteins; Virus Replication; Zidovudine

1990
Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:21

    Topics: Antiviral Agents; Cell Survival; HIV; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Reverse Transcriptase Inhibitors; Thymidine; Thymidine Monophosphate; Thymine Nucleotides; Virus Replication; Zidovudine

1986
Inhibition of replication and cytopathic effect of human T cell lymphotropic virus type III/lymphadenopathy-associated virus by 3'-azido-3'-deoxythymidine in vitro.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:6

    Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; HIV; HIV Antigens; Humans; Reverse Transcriptase Inhibitors; Thymidine; Viral Plaque Assay; Virus Replication; Zidovudine

1986
Ribavirin antagonizes the effect of azidothymidine on HIV replication.
    Science (New York, N.Y.), 1987, Mar-13, Volume: 235, Issue:4794

    Topics: Cell Line; HIV; Humans; Lymphocytes; Monocytes; Phosphorylation; Phytohemagglutinins; Ribavirin; Ribonucleosides; RNA-Directed DNA Polymerase; Thymidine; Virus Replication; Zidovudine

1987
Antiviral therapy.
    Scientific American, 1987, Volume: 256, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cytomegalovirus; DNA, Viral; Drug Resistance, Microbial; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV; Humans; Interferons; Nucleosides; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Messenger; RNA, Viral; Simplexvirus; Thymidine; Virus Diseases; Virus Physiological Phenomena; Virus Replication; Zidovudine

1987
Dextran sulphate, a potent anti-HIV agent in vitro having synergism with zidovudine.
    Lancet (London, England), 1987, Jun-13, Volume: 1, Issue:8546

    Topics: Antiviral Agents; Dextran Sulfate; Dextrans; Drug Synergism; HIV; Humans; Thymidine; Zidovudine

1987
Inhibition of the reverse transcriptase from HIV by 3'-azido-3'-deoxythymidine triphosphate and its threo analogue.
    Antiviral research, 1987, Volume: 7, Issue:3

    Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Dideoxynucleotides; HIV; Humans; Kinetics; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1987
Conformational properties of 3'-azido-3'deoxy-thymidine (AZT), an inhibitor of HIV reverse transcriptase.
    Biochemical and biophysical research communications, 1987, Jun-30, Volume: 145, Issue:3

    Topics: Antiviral Agents; HIV; Models, Molecular; Molecular Conformation; Reverse Transcriptase Inhibitors; Thymidine; Zidovudine

1987
Anti-HIV synergy between dextran sulphate and zidovudine.
    Lancet (London, England), 1987, Aug-22, Volume: 2, Issue:8556

    Topics: Dextran Sulfate; Dextrans; Drug Synergism; HIV; Thymidine; Zidovudine

1987
Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus.
    Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17

    Topics: Antiviral Agents; Deoxycytidine; HIV; Humans; Monocytes; Retroviridae Proteins; RNA-Directed DNA Polymerase; Stavudine; Thymidine; Virus Replication; Zidovudine

1987
Anti-HIV synergism between dextran sulphate and zidovudine.
    Lancet (London, England), 1987, Oct-03, Volume: 2, Issue:8562

    Topics: Antiviral Agents; Dextran Sulfate; Dextrans; Drug Synergism; HIV; Humans; Thymidine; Zidovudine

1987
Synergistic activity of granulocyte-macrophage colony-stimulating factor and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:7

    Topics: Antiviral Agents; Cell Line; Drug Synergism; Fluorescent Antibody Technique; HIV; Humans; Interleukin-3; Recombinant Proteins; RNA-Directed DNA Polymerase; Thymidine; Virus Replication; Zidovudine

1987
Resumption of virus production after human immunodeficiency virus infection of T lymphocytes in the presence of azidothymidine.
    Journal of virology, 1987, Volume: 61, Issue:12

    Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; DNA, Viral; Drug Resistance, Microbial; HIV; Humans; RNA-Directed DNA Polymerase; T-Lymphocytes; Thymidine; Virus Replication; Zidovudine

1987
3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:12

    Topics: Anti-Bacterial Agents; Autoradiography; Cells, Cultured; Dideoxynucleotides; Electrophoresis, Polyacrylamide Gel; HIV; Nucleic Acid Synthesis Inhibitors; Peptide Chain Termination, Translational; Reverse Transcriptase Inhibitors; Substrate Specificity; Templates, Genetic; Thymine Nucleotides; Zidovudine

1987
Conformation and sandwiching of bases by azido groups in the crystal structure of 3'-azido-3'-deoxy-thymidine (AZT), an antiviral agent that inhibits HIV reverse transcriptase.
    Biochemical and biophysical research communications, 1988, Apr-15, Volume: 152, Issue:1

    Topics: Azides; Dideoxynucleotides; HIV; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

1988
Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells.
    Science (New York, N.Y.), 1988, Apr-29, Volume: 240, Issue:4852

    Topics: Antigens, Differentiation, T-Lymphocyte; Cell Line; Dextran Sulfate; Dextrans; Dideoxynucleosides; DNA, Viral; Fluorescent Antibody Technique; HIV; HIV Envelope Protein gp120; Immunologic Techniques; Retroviridae Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Suramin; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Fusion Proteins; Virion; Zidovudine

1988
1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:7

    Topics: Ancitabine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; HIV; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thymidine; Uracil; Zidovudine

1988
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds.
    Journal of virological methods, 1988, Volume: 20, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cell Line, Transformed; Colorimetry; Cytopathogenic Effect, Viral; Dextran Sulfate; Dextrans; Dideoxynucleosides; Drug Evaluation, Preclinical; Heparin; HIV; Humans; Tetrazolium Salts; Thiazoles; Zalcitabine; Zidovudine

1988
Dextran sulfate as an inhibitor against the human immunodeficiency virus.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 189, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dextran Sulfate; Dextrans; HIV; Humans; Interferon Inducers; Microbial Sensitivity Tests; Molecular Weight; Reverse Transcriptase Inhibitors; T-Lymphocytes, Helper-Inducer; Viral Plaque Assay; Virion; Zidovudine

1988
An analysis of the inhibition of replication of HIV and MuLV by some 3'-blocked pyrimidine analogs.
    Biochemical pharmacology, 1989, Jan-01, Volume: 38, Issue:1

    Topics: Animals; Cells, Cultured; HIV; Male; Mice; Mice, Inbred BALB C; Molecular Conformation; Moloney murine leukemia virus; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication; Zidovudine

1989
A rapid and simple colorimetric test for the study of anti-HIV agents.
    AIDS research and human retroviruses, 1988, Volume: 4, Issue:6

    Topics: Antiviral Agents; Cell Line; Colorimetry; Cytopathogenic Effect, Viral; Formazans; HIV; Humans; Microbial Sensitivity Tests; Ribavirin; RNA-Directed DNA Polymerase; Tetrazolium Salts; Thiazoles; Virus Replication; Zidovudine

1988
Nucleotide dimers suppress HIV expression in vitro.
    AIDS research and human retroviruses, 1988, Volume: 4, Issue:6

    Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Dinucleoside Phosphates; HIV; HIV Antigens; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Zidovudine

1988
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
    Science (New York, N.Y.), 1989, Mar-31, Volume: 243, Issue:4899

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Foscarnet; HeLa Cells; HIV; HIV Core Protein p24; Humans; Microbial Sensitivity Tests; Phosphonoacetic Acid; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1989
Kinetics and inhibition of reverse transcriptase from human and simian immunodeficiency viruses.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:12

    Topics: Deoxyguanine Nucleotides; Dideoxynucleotides; HIV; Humans; Kinetics; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Thymine Nucleotides; Zidovudine

1988
In vitro evaluation of mismatched double-stranded RNA (ampligen) for combination therapy in the treatment of acquired immunodeficiency syndrome.
    AIDS research and human retroviruses, 1989, Volume: 5, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Alkaloids; Amphotericin B; Antiviral Agents; Drug Therapy, Combination; Foscarnet; HIV; Humans; In Vitro Techniques; Indolizines; Interferon beta-1a; Interferon beta-1b; Interferon Type I; Interferon-beta; Interferon-gamma; Interferons; Microbial Sensitivity Tests; Phosphonoacetic Acid; Recombinant Proteins; Ribavirin; RNA, Double-Stranded; Zidovudine

1989
Pharmacokinetics of zidovudine and concomitant inosine-pranobex in AIDS patients.
    Immunopharmacology and immunotoxicology, 1988, Volume: 10, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; HIV; Humans; Inosine; Inosine Pranobex; Time Factors; Zidovudine

1988
Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.
    Biochemical and biophysical research communications, 1989, Jun-15, Volume: 161, Issue:2

    Topics: Deoxyguanine Nucleotides; Dideoxynucleosides; Dideoxynucleotides; DNA Primase; HIV; Humans; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; RNA Nucleotidyltransferases; Thymine Nucleotides; Zidovudine

1989
Further characterization of sulfated homopolysaccharides as anti-HIV agents.
    Experientia, 1989, Oct-15, Volume: 45, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dextran Sulfate; Dextrans; Drug Synergism; HIV; Humans; Leukocytes, Mononuclear; Polysaccharides; Reverse Transcriptase Inhibitors; Zidovudine

1989
Phosphorylation of 3'-azido-2',3'-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5'-triphosphate.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:10

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; DNA Polymerase II; HIV; Humans; Kinetics; Phosphorylation; Phosphotransferases; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Thymidine Kinase; Zidovudine

1989
Zidovudine resistant HIV.
    BMJ (Clinical research ed.), 1989, Apr-29, Volume: 298, Issue:6681

    Topics: Acquired Immunodeficiency Syndrome; Drug Resistance, Microbial; HIV; Humans; Zidovudine

1989
Isolation of drug-resistant variants of HIV-1 from patients on long-term zidovudine therapy. Canadian Zidovudine Multi-Centre Study Group.
    AIDS (London, England), 1989, Volume: 3, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Drug Resistance, Microbial; HIV; Humans; Zidovudine

1989
Recombinant human interferon-beta suppresses the replication of HIV and acts synergistically with AZT.
    Journal of interferon research, 1989, Volume: 9, Issue:6

    Topics: Cells, Cultured; Cytopathogenic Effect, Viral; Drug Synergism; Gene Products, gag; HIV; HIV Antigens; HIV Core Protein p24; Humans; Interferon beta-1a; Interferon beta-1b; Interferon Type I; Interferon-beta; Recombinant Proteins; Viral Core Proteins; Virus Replication; Zidovudine

1989
Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virus.
    Journal of medical virology, 1989, Volume: 29, Issue:3

    Topics: Antiviral Agents; Dose-Response Relationship, Drug; Foscarnet; Gene Products, gag; HIV; HIV Antigens; HIV Core Protein p24; Humans; Interferon Type I; Macrophages; Monocytes; Phosphonoacetic Acid; RNA, Viral; Tumor Cells, Cultured; Viral Core Proteins; Virus Replication; Zidovudine

1989
Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
    The Journal of biological chemistry, 1989, Apr-15, Volume: 264, Issue:11

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Deoxyribonucleotides; Dideoxynucleosides; Dose-Response Relationship, Drug; HIV; Humans; Mice; Phosphorylation; Sarcoma Viruses, Murine; Solubility; Stavudine; Thymidine; Zidovudine

1989
Dipyridamole potentiates the inhibition by 3'-azido-3'-deoxythymidine and other dideoxynucleosides of human immunodeficiency virus replication in monocyte-macrophages.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:10

    Topics: Antiviral Agents; Biological Transport; Bone Marrow; Bone Marrow Cells; Cell Survival; Dideoxynucleosides; Dipyridamole; Drug Synergism; HIV; Humans; In Vitro Techniques; Interferon Type I; Macrophages; Monocytes; Virus Replication; Zalcitabine; Zidovudine

1989
In vitro bone marrow toxicity of nucleoside analogs against human immunodeficiency virus.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:4

    Topics: Antiviral Agents; Bone Marrow Diseases; Colony-Forming Units Assay; Dideoxynucleosides; HIV; Humans; Nucleosides; Zalcitabine; Zidovudine

1989
Human immunodeficiency virus inhibition is prolonged by 3'-azido-3'-deoxythymidine alternating with 2',3'-dideoxycytidine compared with 3'-azido-3'-deoxythymidine alone.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Antiviral Agents; Cells, Cultured; Dideoxynucleosides; DNA, Viral; HIV; Humans; Time Factors; Virus Replication; Zalcitabine; Zidovudine

1989
[AIDS: small, life-prolonging steps. Antiviral therapy is more efficient--a decrease in side effects].
    Fortschritte der Medizin, 1989, Sep-10, Volume: 107, Issue:26

    Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Zalcitabine; Zidovudine

1989
A comparison of three nucleoside analogs with anti-retroviral activity on immune and hematopoietic functions in mice: in vitro toxicity to precursor cells and microstromal environment.
    Toxicology and applied pharmacology, 1989, Volume: 101, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antigen-Antibody Reactions; Antiviral Agents; Bone Marrow; Dideoxyadenosine; Female; Hematopoiesis; HIV; Immunity, Cellular; Macrophages; Mice; Mice, Inbred C57BL; Spleen; Stem Cells; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine

1989
The antiretroviral and cytostatic activity, and metabolism of 3'-azido-2',3'-dideoxythymidine, 3'-fluoro-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly cell type-dependent.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Antiviral Agents; Cell Division; Cell Line; Dideoxynucleosides; HIV; Humans; Virus Replication; Zalcitabine; Zidovudine

1989
Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality.
    Lancet (London, England), 1989, May-06, Volume: 1, Issue:8645

    Topics: Acquired Immunodeficiency Syndrome; Follow-Up Studies; HIV; HIV Seropositivity; Humans; Longitudinal Studies; Male; Retrospective Studies; Risk Factors; T-Lymphocytes; Time Factors; Virus Replication; Zidovudine

1989
AIDS therapy.
    The New Zealand medical journal, 1989, Jul-26, Volume: 102, Issue:872

    Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; HIV; Humans; Zidovudine

1989
2'-Deoxycytidine protects normal human bone marrow progenitor cells in vitro against the cytotoxicity of 3'-azido-3'-deoxythymidine with preservation of antiretroviral activity.
    Blood, 1989, Nov-01, Volume: 74, Issue:6

    Topics: Bone Marrow; CD4-Positive T-Lymphocytes; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Deoxycytidine; Deoxycytosine Nucleotides; Hematopoiesis; HIV; Humans; Phosphorylation; Thymine Nucleotides; Zidovudine

1989
Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibody.
    Journal of virology, 1989, Volume: 63, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; HIV; HIV Antibodies; HIV Seropositivity; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Virus Replication; Zidovudine

1989
Pharmacokinetics of orally administered zidovudine among patients with hemophilia and asymptomatic human immunodeficiency virus (HIV) infection.
    Antiviral research, 1989, Volume: 11, Issue:2

    Topics: Administration, Oral; Chromatography, High Pressure Liquid; Hemophilia A; HIV; HIV Seropositivity; Humans; Liver Function Tests; Male; Metabolic Clearance Rate; Zidovudine

1989
Microenvironmental toxicity of azidothymidine: partial sparing with hemin.
    Blood, 1989, Volume: 74, Issue:1

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Dose-Response Relationship, Drug; Erythropoiesis; Hematopoiesis; Hematopoietic Stem Cells; Heme; Hemin; HIV; HIV Antigens; Humans; Mice; Zidovudine

1989
Anti-HIV drugs: comparative toxicities in murine fetal liver and bone marrow erythroid progenitor cells.
    Life sciences, 1989, Volume: 45, Issue:4

    Topics: Animals; Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Dideoxynucleosides; Fetus; Hematopoietic Stem Cells; HIV; Liver; Mice; Ribavirin; Zalcitabine; Zidovudine

1989
Cellular pharmacology of 2',3'-dideoxy-2',3'-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; HIV; Humans; Nucleosides; Phosphorylation; Thymine Nucleotides; Zidovudine

1989
Inhibition of HIV-1 proviral DNA synthesis and RNA accumulation by mismatched dsRNA.
    Biochemical and biophysical research communications, 1989, Feb-15, Volume: 158, Issue:3

    Topics: Antiviral Agents; Cell Line; DNA, Viral; HIV; Interferon Type I; Nucleic Acid Hybridization; Poly I-C; Poly U; Polyribonucleotides; Recombinant Proteins; RNA, Double-Stranded; RNA, Viral; T-Lymphocytes; Transcription, Genetic; Zidovudine

1989
Sensitive and rapid assay on MT-4 cells for detection of antiviral compounds against the AIDS virus.
    Journal of virological methods, 1987, Volume: 16, Issue:3

    Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Deoxycytidine; Flow Cytometry; Fluorescent Antibody Technique; HIV; Humans; Thymidine; Zalcitabine; Zidovudine

1987
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages.
    The Journal of experimental medicine, 1987, Oct-01, Volume: 166, Issue:4

    Topics: Adenosine Kinase; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dideoxyadenosine; HIV; Humans; Macrophages; Phosphorylation; T-Lymphocytes; Thymidine; Thymidine Kinase; Uridine Kinase; Virus Replication; Zalcitabine; Zidovudine

1987
The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species.
    Biochemical pharmacology, 1988, Mar-01, Volume: 37, Issue:5

    Topics: Animals; Antiviral Agents; Cell Line; Deoxycytidine; HIV; Humans; Mice; Mice, Inbred C3H; Moloney murine sarcoma virus; Retroviridae; Thymidine; Zalcitabine; Zidovudine

1988
Anti-human immunodeficiency virus agent 3'-azido-3'-deoxythymidine inhibits replication of Epstein-Barr virus.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:2

    Topics: Cell Line; Cytomegalovirus; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV; Simplexvirus; Thymidine; Virus Replication; Zidovudine

1988
Inhibition of infectivity and replication of HIV-2 and SIV in helper T-cells by 2',3'-dideoxynucleosides in vitro.
    AIDS research and human retroviruses, 1988, Volume: 4, Issue:2

    Topics: Cytopathogenic Effect, Viral; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; HIV; In Vitro Techniques; Nucleosides; Retroviridae; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine

1988
Synergistic interaction of 2',3'-dideoxycytidine and recombinant interferon-alpha-A on replication of human immunodeficiency virus type 1.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:2

    Topics: Antiviral Agents; Cell Line; Deoxycytidine; Drug Synergism; HIV; Humans; Interferon Type I; Leukocytes; Recombinant Proteins; Thymidine; Virus Replication; Zalcitabine; Zidovudine

1988
Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.
    The Journal of experimental medicine, 1988, Sep-01, Volume: 168, Issue:3

    Topics: Antiviral Agents; Deoxycytidine Kinase; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; In Vitro Techniques; Macrophages; Monocytes; Phosphorylation; Thymidine Kinase; Time Factors; Virus Replication; Zalcitabine; Zidovudine

1988
Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro.
    Biochemical and biophysical research communications, 1988, Oct-31, Volume: 156, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Molecular Structure; Structure-Activity Relationship; Virus Replication; Zalcitabine; Zidovudine

1988
Heterogeneity of HIV-1 replication and antigen expression in EBV-transformed B cell lines.
    Leukemia, 1988, Volume: 2, Issue:12 Suppl

    Topics: Antigens, Viral; B-Lymphocytes; Cell Line; Cytopathogenic Effect, Viral; Herpesvirus 4, Human; HIV; Humans; Virus Replication; Zidovudine

1988
Recovery of human immunodeficiency virus from ocular tissues in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1988, Volume: 95, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Infections; Eye; Eye Enucleation; Fluorescent Antibody Technique; HIV; HIV Antigens; Humans; Male; Retinitis; Zidovudine

1988
Mismatched double-stranded RNA (ampligen) reduces concentration of zidovudine (azidothymidine) required for in-vitro inhibition of human immunodeficiency virus.
    Lancet (London, England), 1987, Apr-18, Volume: 1, Issue:8538

    Topics: Antiviral Agents; Cell Line; HIV; Humans; Poly I-C; Poly U; Polyribonucleotides; Thymidine; Virus Replication; Zidovudine

1987
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).
    Lancet (London, England), 1988, Jan-16, Volume: 1, Issue:8577

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Deoxycytidine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; HIV; Humans; Male; Middle Aged; Thymidine; Zalcitabine; Zidovudine

1988
Resumption of HIV antigen production during continuous zidovudine treatment.
    Lancet (London, England), 1988, Feb-20, Volume: 1, Issue:8582

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Viral; Antiviral Agents; HIV; Humans; Thymidine; Zidovudine

1988
Isolation of HIV from mononuclear cells of patients receiving zidovudine.
    Lancet (London, England), 1988, Apr-16, Volume: 1, Issue:8590

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Antiviral Agents; HIV; Humans; Leukocytes, Mononuclear; Thymidine; Zidovudine

1988
Acute meningo-encephalitis on dose reduction of zidovudine.
    Lancet (London, England), 1988, Jun-04, Volume: 1, Issue:8597

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; AIDS-Related Complex; Antiviral Agents; Follow-Up Studies; HIV; Homosexuality; Humans; Male; Meningoencephalitis; Middle Aged; Neutropenia; Thrombocytopenia; Thymidine; Virus Replication; Zidovudine

1988
IVth international AIDS conference.
    Lancet (London, England), 1988, Jul-02, Volume: 2, Issue:8601

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antibodies, Viral; Child; Congresses as Topic; Female; Health Education; HIV; HIV Antibodies; Humans; Male; Sweden; Thymidine; Zidovudine

1988
Acute meningoencephalitis on dose reduction of zidovudine.
    Lancet (London, England), 1988, Sep-03, Volume: 2, Issue:8610

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; HIV; Humans; Meningoencephalitis; Thymidine; Virus Replication; Zidovudine

1988
A highly reliable, sensitive, flow cytometric/fluorometric assay for the evaluation of the anti-HIV activity of antiviral compounds in MT-4 cells.
    Journal of immunological methods, 1988, Nov-10, Volume: 114, Issue:1-2

    Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Fixatives; Flow Cytometry; Fluoresceins; HIV; Humans; Leukocyte Count; Zidovudine

1988
Drug-resistant strains of AIDS virus found.
    Science (New York, N.Y.), 1989, Mar-24, Volume: 243, Issue:4898

    Topics: Acquired Immunodeficiency Syndrome; Drug Resistance, Microbial; HIV; Humans; Zidovudine

1989
5-Chloro-substituted derivatives of 2', 3'-didehydro-2',3'-dideoxyuridine, 3'-fluoro-2',3'-dideoxyuridine and 3'-azido-2',3'-dideoxyuridine as anti-HIV agents.
    Biochemical pharmacology, 1989, Mar-15, Volume: 38, Issue:6

    Topics: Animals; Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Kinetics; Thymidine Kinase; Virus Replication; Zidovudine

1989
AIDS: the virus, antivirals and vaccines.
    British journal of hospital medicine, 1987, Volume: 37, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; Genes, Viral; HIV; Humans; Phosphonoacetic Acid; Suramin; Thymidine; Tungsten; Tungsten Compounds; Viral Vaccines; Virus Replication; Zidovudine

1987
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
    Biochemical and biophysical research communications, 1987, Jan-15, Volume: 142, Issue:1

    Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Structure-Activity Relationship; Thymidine; Virus Replication; Zidovudine

1987
Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro.
    Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3

    Topics: Antiviral Agents; Deoxycytidine; Fluorescence; HIV; Humans; In Vitro Techniques; Monocytes; Thymidine; Zalcitabine; Zidovudine

1987
Substances affecting the infection and replication of human immunodeficiency virus (HIV).
    AIDS research, 1986, Volume: 2 Suppl 1

    Topics: Cell Line; Cytopathogenic Effect, Viral; Deltaretrovirus; Dinoprostone; HIV; Humans; Interferon-gamma; Prostaglandins E; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin; Virus Replication; Zidovudine

1986
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6

    Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1987
Effect of 3'-azido-2',3'-dideoxythymidine (AZT) and neutralizing antibody on human immunodeficiency virus (HIV)-induced cytopathic effects: implication of giant cell formation for the spread of virus in vivo.
    Virology, 1987, Volume: 159, Issue:1

    Topics: Antibodies, Viral; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Antiviral Agents; Cell Fusion; Cytopathogenic Effect, Viral; HIV; Neutralization Tests; T-Lymphocytes; Thymidine; Virus Replication; Zidovudine

1987
Suppression of human immunodeficiency virus replication by 3'-azido-3'-deoxythymidine in various human hematopoietic cell lines in vitro: augmentation of the effect by lentinan.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:6

    Topics: Cell Line; Drug Synergism; Hematopoietic Stem Cells; HIV; Humans; Lentinan; Polysaccharides; T-Lymphocytes; Thymidine; Virus Replication; Zidovudine

1987
Amplification of human immuno-deficiency virus production from a virus-producing cell line in culture at high cell density.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:7

    Topics: Cell Line; Culture Media; Electrophoresis, Polyacrylamide Gel; HIV; Humans; Membrane Proteins; Thymidine; Viral Proteins; Virion; Virology; Virus Replication; Zidovudine

1987
Suppression by neurotropin of production of human immuno-deficiency virus by the virus-producing MOLT-4 cell line.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Surface; Antigens, Viral; Cell Line; HIV; Humans; Polysaccharides; Thymidine; Virion; Virus Replication; Zidovudine

1987
Decline of HIV antigen levels in cerebrospinal fluid during treatment with low-dose zidovudine.
    AIDS (London, England), 1988, Volume: 2, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Viral; Central Nervous System Diseases; HIV; HIV Antigens; Humans; Male; Thymidine; Time Factors; Virus Replication; Zidovudine

1988
HIV antigenemia and zidovudine.
    AIDS (London, England), 1988, Volume: 2, Issue:3

    Topics: Antigens, Viral; Antiviral Agents; HIV; HIV Antigens; Humans; Thymidine; Zidovudine

1988
[HIV infection and AIDS. Paris, 25-29 January 1988].
    Ugeskrift for laeger, 1988, Apr-18, Volume: 150, Issue:16

    Topics: Acquired Immunodeficiency Syndrome; Antibody Formation; HIV; Humans; Thymidine; Zidovudine

1988
[Zidovudin (Retrovir). A new antiviral agents against human immunodeficiency viruses (HIV)].
    Ugeskrift for laeger, 1988, Jan-25, Volume: 150, Issue:4

    Topics: Antiviral Agents; Chemical Phenomena; Chemistry; HIV; Thymidine; Zidovudine

1988
The effect of zidovudine on antigen levels in HIV infection.
    New York state journal of medicine, 1988, Volume: 88, Issue:5

    Topics: Acyclovir; Antigens, Viral; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Antigens; HIV Seropositivity; Humans; Male; Thymidine; Zidovudine

1988
Phosphorylation, anti-HIV activity and cytotoxicity of 3'-fluorothymidine.
    Biochemical and biophysical research communications, 1988, Jun-16, Volume: 153, Issue:2

    Topics: Animals; Antiviral Agents; Cell Division; Cell Line; Cell Survival; Cytidine Diphosphate; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Mice; Phosphorylation; Rats; Thymidine; Virus Replication; Zidovudine

1988
AIDS dementia: synthesis and properties of a derivative of 3'-azido-3'-deoxythymidine (AZT) that may become 'locked' in the central nervous system.
    FEBS letters, 1988, Jul-04, Volume: 234, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Animals; Brain; Cell Line; Chemical Phenomena; Chemistry; Dementia; Dihydropyridines; HIV; Humans; Male; Mice; Moloney murine sarcoma virus; Pharmaceutical Preparations; Prodrugs; Rats; Rats, Inbred Strains; Thymidine; Virus Replication; Zidovudine

1988
[AIDS also an experimental problem. Selection of experimental animals is difficult--no new therapeutic approaches in view].
    Fortschritte der Medizin, 1988, Aug-30, Volume: 106, Issue:25

    Topics: Acquired Immunodeficiency Syndrome; Animals; Disease Models, Animal; HIV; Macaca fascicularis; Zidovudine

1988
In vitro effectiveness of a combination of zidovudine and ansamycin against human immunodeficiency virus.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:4

    Topics: Anti-Bacterial Agents; Drug Interactions; HIV; Humans; Lactams, Macrocyclic; Zidovudine

1988
Uridine reverses the toxicity of 3'-azido-3'-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7

    Topics: Antiviral Agents; Cytidine; HIV; Humans; In Vitro Techniques; Macrophages; Stem Cells; Thymidine; Uridine; Virus Replication; Zidovudine

1988
Significant changes in HIV antigen level in the serum of patients treated with azidothymidine.
    The New England journal of medicine, 1986, Dec-18, Volume: 315, Issue:25

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Viral; Antiviral Agents; HIV; HIV Antigens; Humans; Thymidine; Zidovudine

1986
Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:2

    Topics: Antiviral Agents; Drug Synergism; HIV; Humans; Interferon Type I; Recombinant Proteins; Thymidine; Virus Replication; Zidovudine

1987
Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV-III/LAV)].
    Antiviral research, 1987, Volume: 7, Issue:3

    Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Drug Interactions; Glycyrrhetinic Acid; Glycyrrhizic Acid; HIV; Humans; Thymidine; Zidovudine

1987
Azidothymidine (AZT).
    Connecticut medicine, 1987, Volume: 51, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; HIV; Humans; Thymidine; Zidovudine

1987
Transmission of HIV by antigen presenting cells during T-cell activation: prevention by 3'-azido-3'-deoxythymidine.
    AIDS research and human retroviruses, 1987,Spring, Volume: 3, Issue:1

    Topics: Antigen-Presenting Cells; Antiviral Agents; Cell Line; Cell Survival; HIV; Humans; Lymphocyte Activation; Models, Biological; Radioimmunoassay; T-Lymphocytes; Tetanus Toxoid; Thymidine; Zidovudine

1987
Dideoxynucleosides are less inhibitory in vitro against human immunodeficiency virus type 2 (HIV-2) than against HIV-1.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:12

    Topics: Antiviral Agents; Cell Line; Drug Resistance, Microbial; HIV; Humans; T-Lymphocytes; Thymidine; Virus Replication; Zidovudine

1987
The AIDS virus.
    Scientific American, 1987, Volume: 256, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Animals; Chlorocebus aethiops; Genes, Viral; History, 20th Century; HIV; Humans; Lymphocytes; Thymidine; Viral Envelope Proteins; Viral Vaccines; Zidovudine

1987
Antibacterial activity and mechanism of action of 3'-azido-3'-deoxythymidine (BW A509U).
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:2

    Topics: Antiviral Agents; DNA Replication; DNA, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; HIV; Kinetics; Microbial Sensitivity Tests; Mutation; Thymidine; Thymidine Kinase; Vibrio; Zidovudine

1987