Page last updated: 2024-08-20

yohimbine and Pain

yohimbine has been researched along with Pain in 106 studies

Research

Studies (106)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (23.58)	18.7374
1990's	21 (19.81)	18.2507
2000's	43 (40.57)	29.6817
2010's	17 (16.04)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Haubrich, DR; Hlasta, DJ; Luttinger, D; Perrone, MH; Silbernagel, MJ; Ward, SJ	1
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG	1
Micov, A; Pecikoza, U; Stepanović-Petrović, R; Tomić, M	1
Abelson, KS; Kanui, TI; Makau, CM; Towett, PK	1
Drummond, PD; Vo, L	2
Ciciani, G; Cilibrizzi, A; Crocetti, L; Di Cesare Mannelli, L; Ghelardini, C; Giovannoni, MP; Guerrini, G; Iacovone, A; Vergelli, C	1
Beitz, AJ; Kim, SJ; Kwon, SK; Lee, JH; Roh, DH; Yeo, JH; Yoon, SY	1
Almeida, RN; Aragão Neto, Hde C; Barbosa Filho, JM; Caldas Filho, MR; Fonsêca, DV; Golzio, AM; Leite, FC; Melo, CG; Piuvezam, MR; Pordeus, LC; Salgado, PR	1
Drummond, PD; Hood, S; Vo, L	1
Abelson, KSP; Kanui, TI; Makau, CM; Towett, PK	1
Hagiwara, S; Iwasaka, H; Noguchi, T; Takeshima, N	1
Andurkar, SV; Bhalla, S; Gulati, A; Matwyshyn, G; Zhang, Z	1
Barrot, M; Doridot, S; Freund-Mercier, MJ; Hein, L; Petit-Demoulière, N; Tessier, LH; Yalcin, I	1
Holden, JE; Jeong, Y	1
de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR	1
Ding, Z; Raffa, RB	1
Bilge, SS; Bostanci, MO; Bozkurt, A; Ciftcioglu, E; Dilek, A; Güldogus, F; Ilkaya, F; Ulger, F	1
Pettersen, VL; Raimundo, JM; Sudo, RT; Trachez, MM; Zapata-Sudo, G	1
Mokha, SS; Nag, S	1
Calasans-Maia, JA; Galdino, SL; Hernandes, MZ; Lima, MC; Pitta, IR; Sudo, RT; Zapata-Sudo, G	1
Hsu, SF; Huang, YJ; Li, YL; Sun, WZ; Wang, CC; Wen, YR; Yeh, GC	1
Dukat, M; Scheinin, M; Vainio, M; Young, S	1
Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T	1
Li, JX; Winter, JC; Zhang, Y	1
Andurkar, SV; Gulati, A	1
Bruce, W; Compton, J; Fonder, H; Garrett, N	1
Ferraro, G; Gorzalczany, S; Lopez, P; Miño, J; Morucci, F	1
Abrahão, RQ; Andrade, D; Dale, CS; Franciosi, AC; Giorgi, R; Juliano, L; Juliano, MA	1
Jain, NK; Kulkarni, SK; Singh, A	1
Choi, SS; Han, EJ; Han, KJ; Kim, DH; Lee, HK; Lee, JK; Suh, HW	1
Eger, EI; Laster, MJ; Sonner, JM; Xing, Y	1
Sahebgharani, M; Vousooghi, N; Zarrindast, MR	1
Radhakrishnan, R; Rohlwing, JJ; Skyba, DA; Sluka, KA; Wright, A	1
Kawamura, M; Miura, T; Namba, H; Okai, H; Okazaki, R; Yoshida, H	1
Daniel, D; Flood, P; Rowley, TJ	1
Fukuda, Y; Hasue, F; Kuwaki, T; Shimoyama, M; Yamada, H	1
Angers, P; Dalbó, S; Jürgensen, S; Ribeiro-do-Valle, RM; Santos, AR	1
Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY	1
David, JM; David, JP; Lima-Júnior, RC; Maia, JL; Rao, VS; Santos, FA	1
Abdulla, MM; Hegab, MI	1
Baek, YH; Choi, DY; Huh, JE; Lee, JD; Park, DS	1
Hossein-Abad, AA; Sahebgharani, M; Zarrindast, MR	1
Campos, AR; David, JM; David, JP; Lima-Júnior, RC; Maia, JL; Melo, CM; Rao, VS; Santos, FA	1
Khansefid, N; Ladgevardi, MA; Sabetkasaie, M	1
Fernández-Guasti, A; Jiménez-Velázquez, G; López-Muñoz, FJ	1
Hama, A; Sagen, J	1
Ardenghi, JV; De Souza, MM; Filho, VC; Kanegusuku, M; Monache, FD; Niero, R; Yunes, RA	1
Li, CL; Li, RT; Sun, Q; Ye, J; Yue, CQ	1
Goto, F; Ito, N; Obata, H; Saito, S; Sasaki, M	1
Bruehl, S; Chung, OY; Diedrich, A; Diedrich, L; Robertson, D	1
Bruehl, S; Chont, M; Chung, OY; Diedrich, A; Diedrich, L; Robertson, D	1
Boskovic, B; Prostran, M; Stepanović-Petrovic, R; Tomić, M; Ugresic, N; Vuckovic, S	1
Angelotti, T; Mokha, SS; Nag, S; Thompson, AD	1
Freire, AC; Leonhardt, JH	1
Eisenman, LM; Goldstein, FJ; Malseed, RT; Ossipov, MH	1
Marwaha, J	1
Proudfit, HK; Sagen, J	1
Chipkin, RE; Latranyi, MB	1
Boucher, F; Dennis, SG; Gutman, S; Melzack, R	1
Capasso, A; Di Giannuario, A; Loizzo, A; Pieretti, S; Sorrentino, L	1
Hole, K; Kanui, TI; Lund, A; Mjellem-Joly, N; Tjølsen, A	1
Dawes, P; Rochford, J; Stewart, J	1
Choi, YS; Do, JC; Kim, YH; Lee, KH; Son, KH; Song, DK; Suh, HW; Woo, MH	1
Calixto, JB; Filho, VC; Santos, AR; Yunes, RA	1
Iwasaki, H; Kawamata, M; Kawamata, T; Namiki, A; Omote, K	1
Kawamata, M; Kawamata, T; Namiki, A; Omote, K	1
Kanda, T; Kemmotsu, O; Kida, A; Ohta, Y	1
Lutz, EA; Shannon, HE	2
Muir, WW; Skarda, RT	1
Burton, DD; Camilleri, M; Fett, SL; Kost, L; Malcolm, A; Zinsmeister, AR	1
Buéno, L; Fioramonti, J; Maggi, C; Toulouse, M	1
Alguacil, LF; Morales, L; Perez-Garcia, C	1
Uzbay, IT; Yeşilyurt, O	1
Sahebgharani, M; Zarrindast, MR	1
Fu, TC; Guo, L; Liu, HJ; Peng, YI	1
Besson, JM; Guilbaud, G; Kayser, V	2
Proudfit, HK; Yeomans, DC	1
Bojö, L; Cassuto, J; Nellgård, P	1
Dawes, P; Rochford, J	1
Reid, A; Sawynok, J	1
Foo, H; Westbrook, RF	1
Danzebrink, RM; Gebhart, GF	1
Miller, JF; Proudfit, HK	1
Christensen, MK; Smith, DF	1
Collins, JG; Kitahata, LM; Murata, K; Nakagawa, I; Omote, K	1
Nance, PW; Sawynok, J	1
Barber, A; Harting, J; Wolf, HP	1
Collins, JG; Kitahata, LM; Kumeta, Y; Murata, K; Nakagawa, I	1
Tang, R; Tseng, LL	1
Sotgiu, ML	1
Kobatake, M; Nakamura, A; Shiomi, H; Sugao, T; Yamaue, K	1
Butkhuzi, SM; Kolchin, VV; Moroz, BT; Sakvarelidze, ZA; Zaĭtsev, AA	1
Bansinath, M; Puig, MM; Ramabadran, K; Turndorf, H	1
Jørum, E	1
Simson, PE; Weiss, JM	1
Gebhart, GF; Janss, AJ	1
Barbaro, NM; Fields, HL; Hammond, DL	1
Davies, J; Quinlan, JE	1
Rae, GA; Souza, RL; Takahashi, RN	1
Curtis, AL; Marwah, J	1
Gebhart, GF; Solomon, RE	1
Haigler, HJ; O'Neill, TP	1
Adithan, C; Bapna, JS; Raveendran, R; Sivagnanam, G; Thakur, LC	1

Trials

5 trial(s) available for yohimbine and Pain

Article	Year
Involvement of α2-adrenoceptors in inhibitory and facilitatory pain modulation processes. European journal of pain (London, England), 2016, Volume: 20, Issue:3 Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adult; Blinking; Cold Temperature; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Functional Laterality; Hot Temperature; Humans; Male; Middle Aged; Nociception; Pain; Physical Stimulation; Receptors, Adrenergic, alpha-2; Yohimbine; Young Adult	2016
Involvement of Opioid Receptors and α The journal of pain, 2016, Volume: 17, Issue:11 Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adult; Blood Pressure; Central Nervous System Sensitization; Clonidine; Cross-Over Studies; Double-Blind Method; Drug Administration Routes; Electric Stimulation; Female; Healthy Volunteers; Heart Rate; Humans; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Psychophysics; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine; Young Adult	2016
The relationship between resting blood pressure and acute pain sensitivity: effects of chronic pain and alpha-2 adrenergic blockade. Journal of behavioral medicine, 2008, Volume: 31, Issue:1 Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Fingers; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Pain; Pressure; Receptors, Adrenergic, alpha-2; Yohimbine; Young Adult	2008
Baroreflex sensitivity associated hypoalgesia in healthy states is altered by chronic pain. Pain, 2008, Aug-15, Volume: 138, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Baroreflex; Chronic Disease; Double-Blind Method; Female; Humans; Male; Pain; Pain Threshold; Receptors, Adrenergic, alpha-2; Yohimbine	2008
Effects of intravenously administered yohimbine on antinociceptive, cardiorespiratory, and postural changes induced by epidural administration of detomidine hydrochloride solution to healthy mares. American journal of veterinary research, 1999, Volume: 60, Issue:10 Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics; Animals; Carbon Dioxide; Cardiac Output; Cross-Over Studies; Diuresis; Electric Stimulation; Female; Heart Rate; Hemodynamics; Horses; Imidazoles; Injections, Epidural; Injections, Intravenous; Oxygen; Pain; Posture; Respiratory Mechanics; Sweating; Yohimbine	1999

Other Studies

101 other study(ies) available for yohimbine and Pain

Article	Year
Alpha 2-adrenergic agonists/antagonists: the synthesis and structure-activity relationships of a series of indolin-2-yl and tetrahydroquinolin-2-yl imidazolines. Journal of medicinal chemistry, 1987, Volume: 30, Issue:9 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Imidazoles; Indoles; Male; Mice; Nociceptors; Pain; Prazosin; Quinolines; Rats; Structure-Activity Relationship; Vas Deferens	1987
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship	2008
Eslicarbazepine acetate reduces trigeminal nociception: Possible role of adrenergic, cholinergic and opioid receptors. Life sciences, 2018, Dec-01, Volume: 214 Topics: Adrenergic Antagonists; Analgesics; Animals; Atropine; Cholinergic Antagonists; Dibenzazepines; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Opioid; Trigeminal Neuralgia; Yohimbine	2018
Intrathecal administration of clonidine or yohimbine decreases the nociceptive behavior caused by formalin injection in the marsh terrapin (Pelomedusa subrufa). Brain and behavior, 2014, Volume: 4, Issue:6 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Injections, Spinal; Methysergide; Pain; Pain Measurement; Random Allocation; Serotonin Antagonists; Turtles; Yohimbine	2014
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents. Bioorganic & medicinal chemistry, 2015, Oct-01, Volume: 23, Issue:19 Topics: Acetic Acid; Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Heterocyclic Compounds; Mice; Pain; Pyridazines; Yohimbine	2015
Repetitive Acupuncture Point Treatment with Diluted Bee Venom Relieves Mechanical Allodynia and Restores Intraepidermal Nerve Fiber Loss in Oxaliplatin-Induced Neuropathic Mice. The journal of pain, 2016, Volume: 17, Issue:3 Topics: Acupuncture Points; Acupuncture Therapy; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Bee Venoms; Disease Models, Animal; Epidermis; Foot; Hyperalgesia; Male; Mice, Inbred C57BL; Nerve Fibers; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Threshold; Peripheral Nervous System Diseases; Random Allocation; Receptors, Adrenergic, alpha-2; Touch; Yohimbine	2016
Ortho-eugenol exhibits anti-nociceptive and anti-inflammatory activities. International immunopharmacology, 2016, Volume: 38 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cell Movement; Eugenol; Hot Temperature; Interleukin-1beta; Leukocytes; Male; Mice; Motor Activity; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pain; Tumor Necrosis Factor-alpha; Yohimbine	2016
Modulation of formalin-induced pain-related behaviour by clonidine and yohimbine in the Speke's hinged tortoise (Kiniskys spekii). Journal of veterinary pharmacology and therapeutics, 2017, Volume: 40, Issue:5 Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Pain; Turtles; Yohimbine	2017
Effect of combined opioid receptor and α Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:6 Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adult; Analgesics, Opioid; Anxiety; Blinking; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Pain; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Reflex, Startle; Yohimbine; Young Adult	2017
Mechanisms of analgesic action of pulsed radiofrequency on adjuvant-induced pain in the rat: roles of descending adrenergic and serotonergic systems. European journal of pain (London, England), 2009, Volume: 13, Issue:3 Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Brain Stem; Catecholamines; Catheter Ablation; Disease Models, Animal; Efferent Pathways; Freund's Adjuvant; Inflammation; Male; Neural Inhibition; Nociceptors; Pain; Pain Management; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Serotonin; Serotonin Antagonists; Treatment Outcome; Tropanes; Yohimbine	2009
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874. Pharmacology, 2009, Volume: 83, Issue:1 Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine	2009
Beta2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain. Neurobiology of disease, 2009, Volume: 33, Issue:3 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amines; Animals; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Cyclohexanols; Desipramine; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Transgenic; Morpholines; Pain; Pain Threshold; Propanolamines; Reboxetine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Sciatic Nerve; Venlafaxine Hydrochloride; Yohimbine	2009
Lateral hypothalamic-induced alpha-adrenoceptor modulation occurs in a model of inflammatory pain in rats. Biological research for nursing, 2009, Volume: 10, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Female; Hypothalamic Area, Lateral; Inflammation; Isothiocyanates; Nociceptors; Nursing Research; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Adrenergic, alpha; Tarsus, Animal; Yohimbine	2009
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine. European journal of pharmacology, 2009, Apr-17, Volume: 608, Issue:1-3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Idazoxan; Imidazoles; Leucine; Male; Naloxone; Opioid Peptides; Pain; Pain Measurement; Rats; Rats, Wistar; Xylazine; Yohimbine	2009
Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine. British journal of pharmacology, 2009, Volume: 157, Issue:5 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aminoquinolines; Analgesics, Opioid; Anesthetics, Local; Animals; Benzamides; Brain; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fentanyl; GTP-Binding Proteins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Okadaic Acid; Oligonucleotides, Antisense; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Pertussis Toxin; Phosphoprotein Phosphatases; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, Opioid; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Yohimbine	2009
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors. Anesthesia and analgesia, 2009, Volume: 109, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Catheterization; Clonidine; Colon; Data Interpretation, Statistical; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Physical Stimulation; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Rectum; Yohimbine	2009
The synergistic interaction between morphine and maprotiline after intrathecal injection in rats. Anesthesia and analgesia, 2009, Volume: 109, Issue:4 Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Injections, Spinal; Male; Maprotiline; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Selective Serotonin Reuptake Inhibitors; Time Factors; Yohimbine	2009
Testosterone is essential for alpha(2)-adrenoceptor-induced antinociception in the trigeminal region of the male rat. Neuroscience letters, 2009, Dec-18, Volume: 467, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Catheterization; Clonidine; Estradiol; Estrogens; Hormone Replacement Therapy; Hot Temperature; Male; N-Methylaspartate; Orchiectomy; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Testosterone; Testosterone Propionate; Time Factors; Trigeminal Nuclei; Yohimbine	2009
Interaction of morphine with a new alpha2-adrenoceptor agonist in mice. The journal of pain, 2010, Volume: 11, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Imidazolidines; Isoindoles; Male; Mice; Models, Molecular; Morphine; Pain; Random Allocation; Receptors, Adrenergic, alpha-2; Yohimbine	2010
DNIC-mediated analgesia produced by a supramaximal electrical or a high-dose formalin conditioning stimulus: roles of opioid and alpha2-adrenergic receptors. Journal of biomedical science, 2010, Mar-19, Volume: 17, Issue:1 Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Analgesia; Analysis of Variance; Animals; Area Under Curve; Conditioning, Psychological; Electric Stimulation; Formaldehyde; Immunohistochemistry; Male; Naloxone; Narcotic Antagonists; Neural Inhibition; Pain; Rats; Rats, Sprague-Dawley; Yohimbine	2010
Antinociceptive synergism of MD-354 and clonidine. Part II. The alpha-adrenoceptor component. Basic & clinical pharmacology & toxicology, 2010, Volume: 107, Issue:2 Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Clonidine; Drug Synergism; Guanidines; Imidazoles; Injections, Subcutaneous; Isoindoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Pain; Pain Measurement; Receptors, Adrenergic, alpha; Tail; Yohimbine	2010
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells. Journal of anesthesia, 2011, Volume: 25, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine	2011
Morphine-induced antinociception in the rat: supra-additive interactions with imidazoline I₂ receptor ligands. European journal of pharmacology, 2011, Nov-01, Volume: 669, Issue:1-3 Topics: Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Yohimbine	2011
Assessment of the analgesic effect of centhaquin in mouse tail flick and hot-plate tests. Pharmacology, 2011, Volume: 88, Issue:5-6 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Antihypertensive Agents; Body Temperature; Drug Interactions; Endothelin A Receptor Antagonists; Hot Temperature; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain; Piperazines; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine	2011
Investigation of modulation of the alpha-2 receptor in tetrahydropalmatine (THP) analgesia in male Sprague-Dawley rats. Journal of dietary supplements, 2009, Volume: 6, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics; Analysis of Variance; Animals; Berberine Alkaloids; Corydalis; Dexmedetomidine; Herb-Drug Interactions; Hot Temperature; Hypnotics and Sedatives; Male; Pain; Pain Threshold; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine	2009
Antinociceptive activity of aqueous extract and isolated compounds of Lithrea molleoides. Journal of ethnopharmacology, 2012, Jul-13, Volume: 142, Issue:2 Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Anacardiaceae; Analgesics; Animals; Behavior, Animal; Dopamine Antagonists; Drug Administration Routes; Female; Formaldehyde; Haloperidol; Hot Temperature; Mice; Mice, Inbred Strains; Pain; Phytotherapy; Plant Extracts; Shikimic Acid; South America; Vanillic Acid; Yohimbine	2012
Oligopeptidases B from Trypanossoma cruzi and Trypanossoma brucei inhibit inflammatory pain in mice by targeting serotoninergic receptors. Inflammation, 2013, Volume: 36, Issue:3 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Male; Methysergide; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Serotonin; Serine Endopeptidases; Serotonin Antagonists; Trypanosoma brucei brucei; Trypanosoma cruzi; Yohimbine	2013
Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects. Life sciences, 2002, May-03, Volume: 70, Issue:24 Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergism; Drug Therapy, Combination; Meloxicam; Mice; Naproxen; Pain; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles; Yohimbine	2002
Antinociceptive mechanisms of orally administered decursinol in the mouse. Life sciences, 2003, Jun-13, Volume: 73, Issue:4 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzopyrans; Butyrates; Cyproheptadine; Dose-Response Relationship, Drug; Glutamic Acid; Histamine H2 Antagonists; Interferon-gamma; Interleukin-1; Male; Methysergide; Mice; Mice, Inbred ICR; Models, Chemical; Naloxone; Narcotic Antagonists; Pain; Piperidines; Protein Kinase C; Ranitidine; Receptors, Adrenergic; Receptors, Histamine; Receptors, Purinergic P1; Receptors, Serotonin; Serotonin Antagonists; Substance P; Theobromine; Tumor Necrosis Factor-alpha; Xanthines; Yohimbine	2003
Alpha-2 adrenoreceptors probably do not mediate the immobility produced by inhaled anesthetics. Anesthesia and analgesia, 2003, Volume: 96, Issue:6 Topics: Adrenergic alpha-Antagonists; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Imidazoles; Isoflurane; Male; Movement; Pain; Physical Stimulation; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine	2003
Imipramine-induced antinociception in the formalin test. Receptor mechanisms involved and effect of swim stress. Pharmacology, 2003, Volume: 68, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Imipramine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Naloxone; Nociceptors; Pain; Pain Measurement; Prazosin; Stress, Physiological; Swimming; Yohimbine	2003
Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord. Pain, 2003, Volume: 106, Issue:1-2 Topics: Adrenergic alpha-Antagonists; Animals; Bicuculline; GABA Antagonists; Hyperalgesia; Joints; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain; Pain Management; Physical Stimulation; Physical Therapy Modalities; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, GABA; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Yohimbine	2003
Mechanisms of analgesic action of neurotropin on chronic pain in adjuvant-induced arthritic rat: roles of descending noradrenergic and serotonergic systems. Journal of pharmacological sciences, 2005, Volume: 97, Issue:3 Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arthritis, Experimental; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Lumbosacral Region; Male; Methysergide; Pain; Pain Threshold; Polysaccharides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Time Factors; Tropanes; Yohimbine	2005
The role of adrenergic and cholinergic transmission in volatile anesthetic-induced pain enhancement. Anesthesia and analgesia, 2005, Volume: 100, Issue:4 Topics: Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Benzylamines; Dopamine; Female; Injections, Intraventricular; Injections, Spinal; Isoflurane; Mice; Norepinephrine; Pain; Pain Measurement; Parasympathetic Nervous System; Receptors, Nicotinic; Serotonin; Spinal Cord; Sympathetic Nervous System; Synaptic Transmission; Yohimbine	2005
Inhibitory actions of endothelin-1 on pain processing. Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Neural Pathways; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptides, Cyclic; Piperidines; Prazosin; Reaction Time; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Adrenergic, alpha-1; Yohimbine	2004
Involvement of 5-HT2 receptors in the antinociceptive effect of Uncaria tomentosa. Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:3 Topics: Acetic Acid; Analgesics; Animals; Arginine; Atropine; Behavior, Animal; Capsaicin; Cat's Claw; Dose-Response Relationship, Drug; Formaldehyde; Ketanserin; Male; Mice; Motor Activity; Naltrexone; Pain; Pain Measurement; Phytotherapy; Plant Preparations; Prazosin; Receptors, Serotonin, 5-HT2; Reserpine; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Yohimbine	2005
Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats. European journal of pharmacology, 2005, Oct-31, Volume: 523, Issue:1-3 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cold Temperature; Disease Models, Animal; Hyperalgesia; Male; Nociceptors; Pain; Pain Threshold; Peripheral Nervous System Diseases; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Time Factors; Yohimbine	2005
Oleanolic Acid, a pentacyclic triterpene attenuates the mustard oil-induced colonic nociception in mice. Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Colonic Diseases; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Mustard Plant; Oleanolic Acid; Pain; Plant Oils; Ruthenium Red; TRPV Cation Channels; Yohimbine	2006
4-Chloro-2,2-disubstituted chromen-3-carboxaldehyde: synthesis of some fused polycyclic heterocycles as anti-inflammatory, analgesic, anticonvulsant, and antiparkinsonian agents. Archiv der Pharmazie, 2006, Volume: 339, Issue:1 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antiparkinson Agents; Benzopyrans; Carrageenan; Dinoprostone; Edema; Heterocyclic Compounds; Male; Mice; Oxotremorine; Pain; Parkinsonian Disorders; Rats; Rats, Wistar; Seizures; Time Factors; Yohimbine	2006
Antinociceptive effect and the mechanism of bee venom acupuncture (Apipuncture) on inflammatory pain in the rat model of collagen-induced arthritis: Mediation by alpha2-Adrenoceptors. Brain research, 2006, Feb-16, Volume: 1073-1074 Topics: Acupuncture Points; Adrenergic alpha-Antagonists; Animals; Arthritis, Experimental; Bee Venoms; Behavior, Animal; Collagen; Disease Models, Animal; Drug Administration Routes; Drug Interactions; Male; Naloxone; Narcotic Antagonists; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Adrenergic, alpha-2; Statistics, Nonparametric; Yohimbine	2006
On the mechanism of carbamazepine-induced antinociception in the formalin test. The International journal of neuroscience, 2006, Volume: 116, Issue:9 Topics: Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Formaldehyde; GABA Antagonists; Male; Mice; Organophosphorus Compounds; Pain; Pain Measurement; Prazosin; Yohimbine	2006
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms. Pharmacological research, 2006, Volume: 54, Issue:4 Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Capsaicin; Coloring Agents; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; KATP Channels; Lamiaceae; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Oleanolic Acid; Pain; Pain Measurement; Postural Balance; Potassium Channels, Inwardly Rectifying; Ruthenium Red; Yohimbine	2006
Possible role of NMDA receptors in antinociception induced by rilmenidine in mice in the formalin test. European journal of pain (London, England), 2007, Volume: 11, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzofurans; Binding Sites; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Imidazoles; Imidazoline Receptors; Male; Mice; Nervous System; Neurons, Afferent; Nociceptors; Oxazoles; Pain; Pain Measurement; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Rilmenidine; Yohimbine	2007
Influence of pharmacologically-induced experimental anxiety on nociception and antinociception in rats. European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3 Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Pain; Rats; Rats, Wistar; Time Factors; Yohimbine	2006
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy. European journal of pharmacology, 2007, Mar-15, Volume: 559, Issue:1 Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Time Factors; Tramadol; Yohimbine	2007
Analysis of the mechanism of antinociceptive action of niga-ichigoside F1 obtained from Rubus imperialis (Rosaceae). The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:12 Topics: Analgesics; Animals; Apomorphine; Atropine; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Morphine; Naloxone; Nitroarginine; Pain; Pain Measurement; Plant Extracts; Rosaceae; Saponins; Yohimbine	2006
Antinociceptive effects of the novel spirocyclopiperazinium salt compound LXM-10 in mice. Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:4 Topics: Analgesics; Animals; Atropine; Atropine Derivatives; Body Temperature; Drug Evaluation, Preclinical; Female; Hexamethonium; Male; Mecamylamine; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Pain; Pain Measurement; Piperazines; Psychomotor Performance; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Opioid; Yohimbine	2007
Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury. European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Atropine; Injections, Spinal; Ligation; Male; Muscarinic Antagonists; Norepinephrine; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Piperazines; Pyrazines; Rats; Rats, Wistar; Serotonin 5-HT2 Receptor Agonists; Spinal Cord; Spinal Nerves; Touch; Yohimbine	2007
Role of alpha2-adrenoceptors in the local peripheral antinociception by carbamazepine in a rat model of inflammatory mechanical hyperalgesia. Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:10 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hindlimb; Hyperalgesia; Inflammation; Injections; Male; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine	2007
Sex-specific modulation of spinal nociception by alpha2-adrenoceptors: differential regulation by estrogen and testosterone. Neuroscience, 2008, Jun-02, Volume: 153, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Castration; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Estrogens; Female; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sex Characteristics; Testosterone; Time Factors; Yohimbine	2008
Further studies on the xylazine-yohimbine interaction. Pharmacological research communications, 1984, Volume: 16, Issue:9 Topics: Abdomen; Acetates; Acetic Acid; Animals; Kinetics; Male; Mice; Muscle Cramp; Pain; Receptors, Adrenergic, alpha; Thiazines; Xylazine; Yohimbine	1984
Effect of alpha 2 adrenergic agents upon central etorphine antinociception in the cat. Brain research, 1984, Aug-20, Volume: 309, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Cats; Clonidine; Drug Interactions; Etorphine; Guanfacine; Guanidines; Kinetics; Male; Morphinans; Nociceptors; Pain; Phenylacetates; Yohimbine	1984
Supersensitivity of analgesic responses to alpha 2-adrenergic agonists in genetically hypertensive rats. Brain research, 1984, Jun-25, Volume: 304, Issue:2 Topics: Animals; Clonidine; Hypertension; Male; Naphazoline; Pain; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine	1984
Effect of intrathecally administered noradrenergic antagonists on nociception in the rat. Brain research, 1984, Sep-24, Volume: 310, Issue:2 Topics: Animals; Brain Mapping; Brain Stem; Dioxanes; Efferent Pathways; Injections, Spinal; Male; Norepinephrine; Pain; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine	1984
Subplantar yeast injection induces a non-naloxone reversible antinociception in spontaneously hypertensive rats. Brain research, 1984, Jun-11, Volume: 303, Issue:1 Topics: Animals; Endorphins; Hypertension; Male; Naloxone; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Reaction Time; Yeast, Dried; Yohimbine	1984
Pain modulation by adrenergic agents and morphine as measured by three pain tests. Life sciences, 1980, Apr-14, Volume: 26, Issue:15 Topics: Animals; Drug Interactions; Male; Methods; Morphine; Naloxone; Pain; Rats; Reaction Time; Sympathomimetics; Time Factors; Yohimbine	1980
Effects induced by cysteamine on chemically-induced nociception in mice. Life sciences, 1994, Volume: 54, Issue:15 Topics: Amino Acid Sequence; Animals; Cysteamine; Drug Interactions; Locomotion; Male; Mice; Molecular Sequence Data; Naloxone; Organophosphorus Compounds; Pain; Somatostatin; Yohimbine	1994
Antinociceptive effects of intrathecal administration of alpha-adrenoceptor antagonists and clonidine in the formalin test in the mouse. Neuropharmacology, 1993, Volume: 32, Issue:4 Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Body Temperature; Clonidine; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain; Pain Measurement; Prazosin; Yohimbine	1993
Naloxone potentiation of novelty-induced hypoalgesia: characterization of the alpha-noradrenergic receptor subtype. Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:2 Topics: Animals; Clonidine; Drug Synergism; Habituation, Psychophysiologic; Male; Naloxone; Pain; Phentolamine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine	1993
Antinociceptive effect of smilaxin B administered intracerebroventricularly in the mouse. Planta medica, 1996, Volume: 62, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Cerebral Ventricles; Dizocilpine Maleate; Glycosides; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Muscimol; Naloxone; Pain; Sincalide; Spinal Cord; Spirostans; Yohimbine	1996
Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus. General pharmacology, 1995, Volume: 26, Issue:7 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arginine; Capsaicin; Clonidine; Male; Mice; Nitroarginine; Pain; Phenylephrine; Plant Extracts; Prazosin; Yohimbine	1995
Antinociceptive interaction of intrathecal alpha2-adrenergic agonists, tizanidine and clonidine, with lidocaine in rats. Anesthesiology, 1997, Volume: 87, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Injections, Spinal; Lidocaine; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Yohimbine	1997
Formalin-induced nociception activates a monoaminergic descending inhibitory system. Brain research, 1998, Dec-14, Volume: 814, Issue:1-2 Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Biogenic Monoamines; Formaldehyde; Male; Methysergide; Neural Inhibition; Pain; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Yohimbine	1998
The effect of alpha2-adrenergic drugs on the activity of neurons in the rat nucleus raphe magnus in vitro. Anesthesia and analgesia, 1999, Volume: 88, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Stem; Clonidine; Dose-Response Relationship, Drug; Neural Inhibition; Neural Pathways; Neurons; Nociceptors; Pain; Raphe Nuclei; Rats; Rats, Wistar; Synaptic Transmission; Yohimbine	1999
Effects of the I(1) imidazoline/alpha(2)-adrenergic receptor agonist moxonidine in comparison with clonidine in the formalin test in rats. Pain, 2000, Volume: 85, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Benzofurans; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imidazoles; Imidazoline Receptors; Injections, Subcutaneous; Male; Pain; Pain Measurement; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Drug; Time Factors; Yohimbine	2000
Yohimbine produces antinociception in the formalin test in rats: involvement of serotonin(1A) receptors. Psychopharmacology, 2000, Volume: 149, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Ergolines; Formaldehyde; Male; Nociceptors; Oxadiazoles; Pain; Pain Measurement; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Yohimbine	2000
Towards identifying optimal doses for alpha-2 adrenergic modulation of colonic and rectal motor and sensory function. Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:6 Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nervous System; Clonidine; Colon; Colonic Diseases, Functional; Female; Gases; Gastrointestinal Motility; Humans; Male; Pain; Perception; Receptors, Adrenergic, alpha-2; Rectum; Yohimbine	2000
Role of NK2 receptors in gastric barosensitivity and in experimental ileus in rats. Neurogastroenterology and motility, 2001, Volume: 13, Issue:1 Topics: Adrenergic alpha-Antagonists; Air Pressure; Animals; Behavior, Animal; Electromyography; Injections, Intramuscular; Injections, Intravenous; Intestinal Obstruction; Jejunum; Male; Pain; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Neurokinin-2; Stomach; Yohimbine	2001
Effects of yohimbine on the antinociceptive and place conditioning effects of opioid agonists in rodents. British journal of pharmacology, 2001, Volume: 133, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Conditioning, Psychological; Drug Synergism; Hot Temperature; Male; Mice; Morphine; Motor Activity; Pain; Pain Measurement; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time; Tail; Yohimbine	2001
Agmatine potentiates the analgesic effect of morphine by an alpha(2)-adrenoceptor-mediated mechanism in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:1 Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Male; Mice; Morphine; Nociceptors; Pain; Pain Measurement; Rats; Receptors, Adrenergic, alpha-2; Yohimbine	2001
Effect of alpha-adrenoceptor agonists and antagonists on imipramine-induced antinociception in the rat formalin test. Pharmacology, 2002, Volume: 64, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imipramine; Injections, Intraventricular; Male; Nociceptors; Pain; Pain Measurement; Prazosin; Rats; Rats, Wistar; Yohimbine	2002
Mechanisms of adrenaline-induced antinociception in mice. The Chinese journal of physiology, 1992, Volume: 35, Issue:3 Topics: Analgesics; Animals; Epinephrine; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Pain; Prazosin; Propranolol; Sensory Thresholds; Yohimbine	1992
Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat. European journal of pharmacology, 1992, Nov-24, Volume: 224, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arthritis; Dioxanes; Drug Interactions; Idazoxan; Injections, Intravenous; Norepinephrine; Pain; Pain Measurement; Rats; Receptors, Opioid; Tramadol; Yohimbine	1992
Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat. Brain research, 1992, Oct-09, Volume: 593, Issue:1 Topics: Adrenergic beta-Antagonists; Analgesics; Analysis of Variance; Animals; Arthritis, Experimental; Clonidine; Dioxanes; Idazoxan; Injections, Intravenous; Male; Pain; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Vocalization, Animal; Yohimbine	1992
Antinociception induced by microinjection of substance P into the A7 catecholamine cell group in the rat. Neuroscience, 1992, Volume: 49, Issue:3 Topics: Afferent Pathways; Analgesics; Animals; Blood Pressure; Catecholamines; Dioxanes; Female; Hot Temperature; Idazoxan; Injections, Spinal; Microinjections; Models, Neurological; Neurons; Norepinephrine; Pain; Pons; Rats; Rats, Inbred Strains; Reflex; Serotonin; Skin Temperature; Stereotaxic Techniques; Substance P; Tyrosine 3-Monooxygenase; Yohimbine	1992
Pain-induced inhibition of gastric motility is mediated by adrenergic and vagal non-adrenergic reflexes in the rat. Acta physiologica Scandinavica, 1992, Volume: 146, Issue:3 Topics: Anesthesia; Animals; Autonomic Nervous System; Gastrointestinal Motility; Male; Muscle Relaxation; Neural Pathways; Pain; Prazosin; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vagotomy; Vagus Nerve; Yohimbine	1992
Clonidine and yohimbine modulate the effects of naloxone on novelty-induced hypoalgesia. Psychopharmacology, 1992, Volume: 107, Issue:4 Topics: Animals; Clonidine; Environment; Male; Naloxone; Pain; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine	1992
Noradrenergic and purinergic involvement in spinal antinociception by 5-hydroxytryptamine and 2-methyl-5-hydroxytryptamine. European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Oxidopamine; Pain; Phentolamine; Prazosin; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Purinergic; Serotonin; Spinal Cord; Theophylline; Yohimbine	1991
Naloxone-induced hypoalgesia: effects of noradrenergic antagonists and agonist. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:3 Topics: Animals; Clonidine; Hot Temperature; Male; Naloxone; Norepinephrine; Pain; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Sensory Thresholds; Yohimbine	1991
Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Idazoxan; Male; Pain; Prazosin; Rats; Rats, Inbred Strains; Yohimbine	1990
Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone. Brain research, 1990, Oct-15, Volume: 530, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Electric Stimulation; Female; Injections, Spinal; Methysergide; Microinjections; Naloxone; Neurons; Pain; Phentolamine; Pons; Propranolol; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine	1990
Antinociceptive effects of the stereoisomers of nicotine given intrathecally in spinal rats. Journal of neural transmission. General section, 1990, Volume: 80, Issue:3 Topics: Analgesia; Animals; Injections, Spinal; Male; Mecamylamine; Nicotine; Pain; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Yohimbine	1990
Serotonergic mediation of spinal analgesia and its interaction with noradrenergic systems. Anesthesiology, 1990, Volume: 73, Issue:3 Topics: Anesthesia, Spinal; Animals; Cats; Female; Injections, Intravenous; Injections, Spinal; Male; Methysergide; Naloxone; Neurons; Pain; Serotonin; Serotonin Antagonists; Yohimbine	1990
Substance P-induced long-term blockade of spinal adrenergic analgesia: reversal by morphine and naloxone. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:3 Topics: Analgesia; Animals; Clonidine; Kinetics; Male; Morphine; Naloxone; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Time Factors; Yohimbine	1987
Antinociceptive effects of the 5-HT2 antagonist ritanserin in rats: evidence for an activation of descending monoaminergic pathways in the spinal cord. Neuroscience letters, 1989, Apr-24, Volume: 99, Issue:1-2 Topics: Animals; Methysergide; Nociceptors; Pain; Piperidines; Rats; Receptors, Serotonin; Ritanserin; Spinal Cord; Yohimbine	1989
Intrathecal clonidine suppresses noxiously evoked activity of spinal wide dynamic range neurons in cats. Anesthesia and analgesia, 1989, Volume: 69, Issue:2 Topics: Analgesics; Animals; Blood Pressure; Cats; Clonidine; Decerebrate State; Drug Combinations; Female; Injections, Spinal; Male; Morphine; Neurons; Pain; Receptors, Adrenergic, alpha; Spinal Cord; Spinothalamic Tracts; Synaptic Transmission; Yohimbine	1989
Differential actions of the blockade of spinal opioid, adrenergic and serotonergic receptors on the tail-flick inhibition induced by morphine microinjected into dorsal raphe and central gray in rats. Neuroscience, 1989, Volume: 33, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mesencephalon; Methysergide; Morphine; Naloxone; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Receptors, Serotonin; Spinal Cord; Yohimbine	1989
Effects of alpha 2-adrenoceptors blockade on the inhibition of the nociceptive jaw-opening reflex by the lateral reticular nucleus in rabbits. Archives italiennes de biologie, 1989, Volume: 127, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Medulla Oblongata; Pain; Rabbits; Receptors, Adrenergic, alpha; Reflex; Yohimbine	1989
Involvement of spinal noradrenergic system in the mechanism of an antinociceptive effect of delta-sleep-inducing peptide (DSIP). Brain research, 1989, Feb-20, Volume: 480, Issue:1-2 Topics: Adrenergic Fibers; Analgesia; Animals; Delta Sleep-Inducing Peptide; Male; Mice; Pain; Phentolamine; Spinal Cord; Time Factors; Yohimbine	1989
[Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord]. Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:8 Topics: Animals; Cats; Clonidine; Mesencephalon; Naloxone; Neurons; Nociceptors; Pain; Prazosin; Spinal Cord; Yohimbine	1989
Effect of yohimbine on nociceptive threshold in normoglycemic and streptozotocin-treated hyperglycemic mice. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2 Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Naloxone; Pain; Reaction Time; Sensory Thresholds; Temperature; Yohimbine	1989
Noradrenergic mechanisms in mediation of stress-induced hyperalgesia in rats. Pain, 1988, Volume: 32, Issue:3 Topics: Analgesia; Animals; Clonidine; Diazepam; Norepinephrine; Pain; Rats; Receptors, Adrenergic, alpha; Stress, Physiological; Vibration; Yohimbine	1988
Alpha-2 receptor blockade increases responsiveness of locus coeruleus neurons to excitatory stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Injections, Intravenous; Locus Coeruleus; Male; Neurons; Nicotine; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Yohimbine	1987
Spinal monoaminergic receptors mediate the antinociception produced by glutamate in the medullary lateral reticular nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:9 Topics: Animals; Electric Stimulation; Glutamates; Glutamic Acid; Hot Temperature; Male; Methysergide; Microinjections; Naloxone; Nociceptors; Pain; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reticular Formation; Yohimbine	1987
Effects of intrathecally administered methysergide and yohimbine on microstimulation-produced antinociception in the rat. Brain research, 1985, Sep-23, Volume: 343, Issue:2 Topics: Animals; Electric Stimulation; Foot; Male; Methysergide; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reticular Formation; Tail; Yohimbine	1985
Selective inhibition of responses of feline dorsal horn neurones to noxious cutaneous stimuli by tizanidine (DS103-282) and noradrenaline: involvement of alpha 2-adrenoceptors. Neuroscience, 1985, Volume: 16, Issue:3 Topics: Animals; Cats; Clonidine; Female; Male; Neurons, Afferent; Norepinephrine; Pain; Receptors, Adrenergic, alpha; Sensation; Skin; Spinal Cord; Yohimbine	1985
Methylnalorphinium fails to reverse naloxone-sensitive stress-induced analgesia in mice. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4 Topics: Analgesia; Animals; Cold Temperature; Endorphins; Male; Mice; Nalorphine; Naloxone; Nervous System; Pain; Restraint, Physical; Stress, Physiological; Synaptic Transmission; Yohimbine	1986
Evidence for alpha adrenoceptor modulation of the nociceptive jaw-opening reflex in rats and rabbits. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2 Topics: Analgesia; Animals; Clonidine; Dental Pulp; Electromyography; Jaw; Male; Pain; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Yohimbine	1986
Intrathecal morphine and clonidine: antinociceptive tolerance and cross-tolerance and effects on blood pressure. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2 Topics: Animals; Blood Pressure; Clonidine; Drug Administration Schedule; Drug Tolerance; Injections, Spinal; Male; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Yohimbine	1988
Effects of clonidine on neuronal firing evoked by a noxious stimulus. Brain research, 1985, Feb-18, Volume: 327, Issue:1-2 Topics: Animals; Clonidine; Electrophysiology; Isoquinolines; Male; Neurons; Norepinephrine; Pain; Physical Stimulation; Piperazines; Piperoxan; Rats; Rats, Inbred Strains; Stimulation, Chemical; Yohimbine	1985
Alphamethyldopa analgesia: its possible mechanism of action. Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1 Topics: Analgesics; Animals; Male; Methyldopa; Mice; Naloxone; Pain; Physostigmine; Reaction Time; Time Factors; Yohimbine	1985