y 27632 has been researched along with Fibrosis in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 4 (30.77) | 2.80 |
| Authors | Studies |
|---|---|
| Ghobrial, RM; Kloc, M; Subuddhi, A; Ubelaker, HV; Uosef, A; Zou, D | 1 |
| Chen, P; DiSanto, ME; Fu, X; Guo, Y; Li, Y; Liu, D; Liu, H; Qiu, J; Shan, S; Su, M; Wang, X; Wang, Z; Yang, S; Zeng, G; Zhang, J; Zhang, X; Zhou, Y | 1 |
| Bulus, N; Chen, J; Fogo, AB; Harris, RC; He, Q; Wang, X; Zhang, MZ | 1 |
| Liao, SL; Wang, CC; Wang, SH; Wei, YH; Yang, CH | 1 |
| Ding, H; Du, Y; Li, X; Sun, W; Zeng, Y; Zhao, H; Zhao, L; Zhao, S | 1 |
| Gu, M; Liu, M; Wu, Y; Yin, C; Zhang, W; Zhang, WJ; Zhu, P | 1 |
| Dimaio, JM; Gerard, RD; Kinoshita, H; Kuwahara, K; Olson, EN; Richardson, JA; Sadek, H; Small, EM; Sutherland, LB; Thatcher, JE | 1 |
| Ge, J; Jia, J; Li, L; Sun, A; Wang, K; Wang, S; Zhao, G; Zou, Y | 1 |
| Chen, C; de Borst, MH; Ding, G; Dolman, ME; Hillebrands, JL; Kok, RJ; Lacombe, M; Poosti, F; Prakash, J; van den Born, J; van Goor, H; Yazdani, S | 1 |
| Bourgier, C; Bourhis, J; François, A; Haydont, V; Holler, V; Lasser, P; Mathé, D; Milliat, F; Vozenin-Brotons, MC | 1 |
| Matsumoto, H; Narahara, H; Nasu, K; Nishida, M; Yuge, A | 1 |
| Abe, H; Fujikura, Y; Ina, K; Kitamura, H; Miyazaki, T; Tatsukawa, S | 1 |
| Ando, A; Hori, M; Imai, E; Kawada, N; Moriyama, T; Murozono, T; Nagatoya, K; Oseto, S; Takeji, M | 1 |
13 other study(ies) available for y 27632 and Fibrosis
| Article | Year |
|---|---|
Comparative transcriptome profile of mouse macrophages treated with the RhoA/Rock pathway inhibitors Y27632, Fingolimod (Gilenya), and Rezurock (Belumosudil, SLx-2119).
Topics: Actins; Animals; Fibrosis; Fingolimod Hydrochloride; Graft vs Host Disease; Humans; Macrophages; Mice; rho-Associated Kinases; rhoA GTP-Binding Protein; Transcriptome | 2023 |
Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles.
Topics: Animals; beta Catenin; Cell Proliferation; Fibrosis; Humans; Male; Prostatic Hyperplasia; Rats; Wnt Signaling Pathway | 2023 |
YAP Activation in Renal Proximal Tubule Cells Drives Diabetic Renal Interstitial Fibrogenesis.
Topics: Adaptor Proteins, Signal Transducing; Amides; Animals; Cell Cycle Proteins; Chromones; Diabetes Mellitus, Experimental; ErbB Receptors; Fibrosis; Gene Expression Regulation; HEK293 Cells; Humans; Kidney Diseases; Mice; Mice, Knockout; Morpholines; Nitric Oxide Synthase Type III; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transcription Factors; YAP-Signaling Proteins | 2020 |
Simvastatin and ROCK Inhibitor Y-27632 Inhibit Myofibroblast Differentiation of Graves' Ophthalmopathy-Derived Orbital Fibroblasts
Topics: Adult; Amides; Cell Differentiation; Female; Fibrosis; Graves Ophthalmopathy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; MAP Kinase Signaling System; Middle Aged; Myofibroblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Primary Cell Culture; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Simvastatin; Transforming Growth Factor beta | 2020 |
Microengineered in vitro model of cardiac fibrosis through modulating myofibroblast mechanotransduction.
Topics: Amides; Animals; Cardiovascular Agents; Cell Proliferation; Cells, Cultured; Drug Discovery; Fibrosis; Heart Diseases; Male; Mechanotransduction, Cellular; Mice; Models, Cardiovascular; Myofibroblasts; NIH 3T3 Cells; Pyridines; Rats, Sprague-Dawley | 2014 |
Therapeutic effect of Y-27632 on chronic allograft nephropathy in rats.
Topics: Actins; Amides; Animals; Chemokine CCL2; Chemokine CCL5; Chronic Disease; Delayed Graft Function; Enzyme Inhibitors; Fibrosis; Kidney Transplantation; Male; Nephritis; NF-kappa B; Pyridines; Rats; Rats, Inbred F344; Rats, Inbred Lew; rho-Associated Kinases; Transforming Growth Factor beta1; Transplantation, Homologous | 2009 |
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.
Topics: Amides; Angiotensin II; Animals; Base Sequence; Cell Transdifferentiation; Chlorocebus aethiops; Collagen; Collagen Type I; COS Cells; Disease Models, Animal; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Male; Mice; Mice, Knockout; Molecular Sequence Data; Myocardial Infarction; Myocardium; Myocytes, Smooth Muscle; Phenotype; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta1; Ventricular Remodeling | 2010 |
Up-regulation of BMP-2 antagonizes TGF-β1/ROCK-enhanced cardiac fibrotic signalling through activation of Smurf1/Smad6 complex.
Topics: Amides; Animals; Benzamides; Blotting, Western; Bone Morphogenetic Protein 2; Cell Differentiation; Cells, Cultured; Dioxoles; Fibrosis; Gene Knockdown Techniques; Heart; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C-delta; Pyridines; rho-Associated Kinases; Sequence Analysis, RNA; Signal Transduction; Smad6 Protein; Transforming Growth Factor beta1; Ubiquitin-Protein Ligases; Up-Regulation | 2012 |
Targeted inhibition of renal Rho kinase reduces macrophage infiltration and lymphangiogenesis in acute renal allograft rejection.
Topics: Amides; Animals; Chemokine CCL2; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Gene Expression Regulation; Graft Rejection; Kidney Transplantation; Kidney Tubules, Proximal; Lymphangiogenesis; Macrophages; Male; Protein Kinase Inhibitors; Pyridines; Rats; rho-Associated Kinases | 2012 |
Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression.
Topics: Actins; Adult; Aged; Aged, 80 and over; Amides; Cell Differentiation; Cells, Cultured; Connective Tissue Growth Factor; Cytoskeleton; DNA-Binding Proteins; Enteritis; Enzyme Inhibitors; Female; Fibrosis; Gene Expression Profiling; Humans; Ileum; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle, Smooth; NF-kappa B; Protein Serine-Threonine Kinases; Pyridines; Radiation Injuries; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2005 |
Collagen gel contractility is enhanced in human endometriotic stromal cells: a possible mechanism underlying the pathogenesis of endometriosis-associated fibrosis.
Topics: Actins; Adult; Amides; Cell Differentiation; Collagen; Endometriosis; Endometrium; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibrosis; Gels; Humans; Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Stromal Cells; Tetrazolium Salts; Thiazoles | 2007 |
Contraction of tubulointerstitial fibrosis tissue in diabetic nephropathy, as demonstrated in an in vitro fibrosis model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cells, Cultured; Collagen; Cytochalasin D; Diabetic Nephropathies; Diacetyl; Fibroblasts; Fibrosis; Kidney Tubules; Microscopy, Electron, Transmission; Models, Biological; Myosin Light Chains; Phosphorylation; Pyridines; Rats; rho-Associated Kinases; Transforming Growth Factor beta1; Wound Healing | 2007 |
Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction.
Topics: Actins; Administration, Oral; Amides; Animals; Cell Division; Cell Movement; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Fibrosis; Gene Expression; Intracellular Signaling Peptides and Proteins; Kidney; Macrophages; Mice; Nephritis, Interstitial; Protein Serine-Threonine Kinases; Pyridines; ras Proteins; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; rhoC GTP-Binding Protein; RNA, Messenger; Signal Transduction; Ureteral Obstruction | 2002 |