vigabatrin has been researched along with Edema in 3 studies
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin (Sabril, Hoechst Marion Roussel) is an antiepilepsy drug (AED) presently marketed in 64 countries for the treatment of partial and secondarily generalized seizures." | 8.80 | The potential for vigabatrin-induced intramyelinic edema in humans. ( Brigell, MG; Cohen, JA; Fisher, RS; Peyster, RG; Sze, G, 2000) |
| "Two toxicologic studies of vigabatrin were conducted with immature Sprague Dawley rats to characterize intramyelinic edema (IME) formation and assess potential impact on behavioral measures." | 7.77 | Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema. ( Bekersky, I; Collins, S; Garman, R; Jortner, B; Patterson, R; Sagar, S; Tolbert, D; Walzer, M; Wanaski, S, 2011) |
| "Vigabatrin (Sabril, Hoechst Marion Roussel) is an antiepilepsy drug (AED) presently marketed in 64 countries for the treatment of partial and secondarily generalized seizures." | 4.80 | The potential for vigabatrin-induced intramyelinic edema in humans. ( Brigell, MG; Cohen, JA; Fisher, RS; Peyster, RG; Sze, G, 2000) |
| "Two toxicologic studies of vigabatrin were conducted with immature Sprague Dawley rats to characterize intramyelinic edema (IME) formation and assess potential impact on behavioral measures." | 3.77 | Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema. ( Bekersky, I; Collins, S; Garman, R; Jortner, B; Patterson, R; Sagar, S; Tolbert, D; Walzer, M; Wanaski, S, 2011) |
| "Vigabatrin is an effective antiepileptic drug (AED) for the treatment of refractory complex partial seizures (rCPS) and infantile spasms (IS)." | 2.47 | Non-vision adverse events with vigabatrin therapy. ( Kälviäinen, R; Walker, SD, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walzer, M | 1 |
| Bekersky, I | 1 |
| Wanaski, S | 1 |
| Collins, S | 1 |
| Jortner, B | 1 |
| Patterson, R | 1 |
| Garman, R | 1 |
| Sagar, S | 1 |
| Tolbert, D | 1 |
| Walker, SD | 1 |
| Kälviäinen, R | 1 |
| Cohen, JA | 1 |
| Fisher, RS | 1 |
| Brigell, MG | 1 |
| Peyster, RG | 1 |
| Sze, G | 1 |
2 reviews available for vigabatrin and Edema
| Article | Year |
|---|---|
Non-vision adverse events with vigabatrin therapy.
Topics: 4-Aminobutyrate Transaminase; Adolescent; Adult; Animals; Anticonvulsants; Brain Diseases; Cognition | 2011 |
The potential for vigabatrin-induced intramyelinic edema in humans.
Topics: Animals; Anticonvulsants; Brain; Brain Diseases; Clinical Trials as Topic; Dogs; Edema; Epilepsy; Ev | 2000 |
1 other study available for vigabatrin and Edema
| Article | Year |
|---|---|
Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema.
Topics: Administration, Oral; Age Factors; Animals; Behavior, Animal; Body Weight; Brain; Dose-Response Rela | 2011 |