vigabatrin has been researched along with Aging in 7 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, it is unclear whether the conductive hearing loss caused by otitis media in early age will affect sound tolerance later in life." | 1.37 | Early age conductive hearing loss causes audiogenic seizure and hyperacusis behavior. ( Allman, B; Fu, Q; Jayaram, A; Kumaraguru, A; Li, J; Manohar, S; Sun, W, 2011) |
| " The plasma concentration ratio of the [R] to [S] enantiomers appears to remain constant across the vigabatrin dosage interval in adult volunteers, and in the present study this has also proved to be the case in 12 chronically treated adult epileptic patients." | 1.29 | Plasma vigabatrin enantiomer ratios in adults and children. ( Appleton, DB; Burke, CJ; Eadie, MJ; Nagarajan, L; Schramm, T, 1993) |
| " In group I, the half-life of the R(-) isomer was significantly shorter than that of the S(+) isomer; in group II, the half-lives were comparable." | 1.28 | Pharmacokinetics of the individual enantiomers of vigabatrin (gamma-vinyl GABA) in epileptic children. ( Beaumont, D; Chiron, C; D'Athis, P; Dulac, O; Olive, G; Pons, G; Rey, E; Richard, MO; Vauzelle, F, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brecht, EJ | 1 |
| Barsz, K | 1 |
| Gross, B | 1 |
| Walton, JP | 1 |
| Sun, W | 1 |
| Manohar, S | 1 |
| Jayaram, A | 1 |
| Kumaraguru, A | 1 |
| Fu, Q | 1 |
| Li, J | 1 |
| Allman, B | 1 |
| Gleich, O | 1 |
| Hamann, I | 1 |
| Klump, GM | 1 |
| Kittel, M | 1 |
| Strutz, J | 1 |
| Levav, T | 1 |
| Wirthaim, O | 1 |
| Weiss, R | 1 |
| Grossman, Y | 1 |
| Golan, H | 1 |
| Nagarajan, L | 1 |
| Schramm, T | 1 |
| Appleton, DB | 1 |
| Burke, CJ | 1 |
| Eadie, MJ | 1 |
| Rey, E | 1 |
| Pons, G | 1 |
| Richard, MO | 1 |
| Vauzelle, F | 1 |
| D'Athis, P | 1 |
| Chiron, C | 1 |
| Dulac, O | 1 |
| Beaumont, D | 1 |
| Olive, G | 1 |
| Haegele, KD | 1 |
| Huebert, ND | 1 |
| Ebel, M | 1 |
| Tell, GP | 1 |
| Schechter, PJ | 1 |
7 other studies available for vigabatrin and Aging
| Article | Year |
|---|---|
Increasing GABA reverses age-related alterations in excitatory receptive fields and intensity coding of auditory midbrain neurons in aged mice.
Topics: 4-Aminobutyrate Transaminase; Acoustic Stimulation; Aging; Animals; Anticonvulsants; Auditory Percep | 2017 |
Early age conductive hearing loss causes audiogenic seizure and hyperacusis behavior.
Topics: Acoustic Stimulation; Age Factors; Aging; Animals; Anticonvulsants; Auditory Perception; Behavior, A | 2011 |
Boosting GABA improves impaired auditory temporal resolution in the gerbil.
Topics: Acoustic Stimulation; Aging; Animals; Anticonvulsants; Auditory Pathways; Auditory Perceptual Disord | 2003 |
Impaired synaptogenesis and long-term modulation of behavior following postnatal elevation of GABA levels in mice.
Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Blotting, Western; Cerebral Cor | 2008 |
Plasma vigabatrin enantiomer ratios in adults and children.
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Femal | 1993 |
Pharmacokinetics of the individual enantiomers of vigabatrin (gamma-vinyl GABA) in epileptic children.
Topics: Adolescent; Aging; Aminocaproates; Anticonvulsants; Child; Epilepsy; Humans; Infant; Stereoisomerism | 1990 |
Pharmacokinetics of vigabatrin: implications of creatinine clearance.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Aminocaproates; Creatinine; Female; Hum | 1988 |