Page last updated: 2024-10-21

vanillin and Pain

vanillin has been researched along with Pain in 7 studies

Vanilla: A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Vanillic acid (1) is a flavoring agent found in edible plants and fruits."5.42Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice. ( Baracat, MM; Calixto-Campos, C; Carvalho, TT; Casagrande, R; Fattori, V; Georgetti, SR; Hohmann, MS; Manchope, MF; Pinho-Ribeiro, FA; Verri, WA; Zarpelon, AC, 2015)
"It is necessary to treat neonatal pain because it may have short- and long-term adverse effects."3.11Comparison of the analgesic effect of inhaled lavender vs vanilla essential oil for neonatal frenotomy: a randomized clinical trial (NCT04867824). ( Candel-Pau, J; Fàbregas-Mitjans, M; Garcia-Garcia, J; Llufriu-Marquès, RM; López-Vílchez, MÁ; Maya-Enero, S, 2022)
"Vanillic acid (1) is a flavoring agent found in edible plants and fruits."1.42Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice. ( Baracat, MM; Calixto-Campos, C; Carvalho, TT; Casagrande, R; Fattori, V; Georgetti, SR; Hohmann, MS; Manchope, MF; Pinho-Ribeiro, FA; Verri, WA; Zarpelon, AC, 2015)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Calixto-Campos, C1
Carvalho, TT1
Hohmann, MS1
Pinho-Ribeiro, FA1
Fattori, V1
Manchope, MF1
Zarpelon, AC1
Baracat, MM1
Georgetti, SR1
Casagrande, R1
Verri, WA1
Park, SH1
Sim, YB1
Choi, SM1
Seo, YJ1
Kwon, MS1
Lee, JK1
Suh, HW1
Lötsch, J1
Walter, C1
Felden, L1
Nöth, U1
Deichmann, R1
Oertel, BG1
Hail, N1
Kobal, G1
Maya-Enero, S1
Fàbregas-Mitjans, M1
Llufriu-Marquès, RM1
Candel-Pau, J1
Garcia-Garcia, J1
López-Vílchez, MÁ1
Jebreili, M1
Neshat, H1
Seyyedrasouli, A1
Ghojazade, M1
Hosseini, MB1
Hamishehkar, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Lavender vs Vanilla Essential Oil as Complementary Analgesia for Frenotomy in Healthy Newborns: a Randomized Clinical Trial.[NCT04867824]142 participants (Anticipated)Interventional2021-05-10Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for vanillin and Pain

ArticleYear
Mechanisms of vanilloid-induced apoptosis.
    Apoptosis : an international journal on programmed cell death, 2003, Volume: 8, Issue:3

    Topics: Animals; Apoptosis; Benzaldehydes; Cell Membrane; Humans; Neurons, Afferent; Pain; Reactive Oxygen S

2003

Trials

1 trial available for vanillin and Pain

ArticleYear
Comparison of the analgesic effect of inhaled lavender vs vanilla essential oil for neonatal frenotomy: a randomized clinical trial (NCT04867824).
    European journal of pediatrics, 2022, Volume: 181, Issue:11

    Topics: Analgesics; Ankyloglossia; Breast Feeding; Female; Humans; Hypnotics and Sedatives; Infant, Newborn;

2022

Other Studies

5 other studies available for vanillin and Pain

ArticleYear
Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice.
    Journal of natural products, 2015, Aug-28, Volume: 78, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Benzaldehydes; Benzoquinones; Carrageen

2015
Antinociceptive profiles and mechanisms of orally administered vanillin in the mice.
    Archives of pharmacal research, 2009, Volume: 32, Issue:11

    Topics: Administration, Oral; Analgesics; Animals; Benzaldehydes; Disease Models, Animal; Dose-Response Rela

2009
The human operculo-insular cortex is pain-preferentially but not pain-exclusively activated by trigeminal and olfactory stimuli.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Adult; Benzaldehydes; Brain Mapping; Carbon Dioxide; Female; Humans; Hydrogen Sulfide; Magnetic Reso

2012
A new extension to the University of Erlangen Smell Test (UEST).
    Chemical senses, 2005, Volume: 30 Suppl 1

    Topics: Benzaldehydes; Carbon Dioxide; Evoked Potentials; Humans; Hydrogen Sulfide; Models, Biological; Mode

2005
Comparison of Breastmilk Odor and Vanilla Odor on Mitigating Premature Infants' Response to Pain During and After Venipuncture.
    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2015, Volume: 10, Issue:7

    Topics: Breast Feeding; Female; Humans; Infant Behavior; Infant Nutritional Physiological Phenomena; Infant,

2015