valine has been researched along with Neoplasms in 65 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (26.15) | 18.7374 |
1990's | 9 (13.85) | 18.2507 |
2000's | 18 (27.69) | 29.6817 |
2010's | 18 (27.69) | 24.3611 |
2020's | 3 (4.62) | 2.80 |
Authors | Studies |
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Chan, TH; Tsoi, MF; Yung Cheung, BM | 1 |
Cho, JY; Chung, J; Ho Ryu, K; Kang, JW; Kim, HK; Kim, JY; Kim, K; Kim, M; Kim, SJ; Kim, SM; Kim, TS; Kim, Y; Kwak, MH; Lee, KS; Park, JW; Park, YW; Yoon, S; Yun, T | 1 |
Fujita, Y; Itoh, T; Jebri, I; Tsujita, K | 1 |
Alghamdi, Y; Bottrill, AR; Browne, G; Bushel, M; Karountzos, A; Mistry, S; Pringle, JH; Sayan, AE; Smith, E; Stevens, C; Tulchinsky, E; Wan Makhtar, WR | 1 |
Agarwal, P; Chen, SC; Fine, BM; Gibiansky, L; Girish, S; Jin, JY; Kågedal, M; Koppada, N; Li, C; Lu, D; Saad, O; Samineni, D; Wang, B; Wang, X; Xu, J | 1 |
Hess, KR; Hong, DS; Meric-Bernstam, F; Sen, S; Subbiah, V | 1 |
Angelidakis, G; Blechacz, B; Economides, MP; Granwehr, BP; Hosry, J; Jiang, Y; Kaseb, A; Kyvernitakis, A; Mahale, P; Miller, E; Naing, A; Raad, II; Samaniego, F; Torres, HA | 1 |
Dora, CP; Jain, S; Katiyar, SS; Kushwah, V | 1 |
Cai, E; Dai, M; Han, M; Jia, X; Jiang, S; Shu, H; Sun, N; Yang, L | 1 |
Fine, BM; Gillespie, WR; Girish, S; Jin, JY; Kågedal, M; Li, C; Lu, D; Samineni, D | 1 |
Cha, H; Cho, WJ; Dung, le TK; Lee, HY; Lee, SJ; Min, YJ; Moon, CH; Park, JW | 1 |
Cheng, H; Lu, J; Qin, Q; Sun, X; Xu, L; Yang, X; Zhan, L; Zhang, C; Zhu, H | 1 |
Eli, M; Kong, B; Mamtimin, B; Turahun, A; Upur, H | 1 |
Cesari, R; Cleary, JM; Dasari, A; English, PA; Huang, B; Jimeno, A; Kern, KA; LoRusso, PM; McLachlan, KR; Messersmith, WA; Reynolds, JM; Shaik, MN; Shapiro, GI; Zheng, X | 1 |
Hughes, DP; Kummar, S; Lazar, AJ | 1 |
Bang, YJ; Han, SW; Jang, IJ; Kim, JH; Kim, TM; Kim, TY; Lee, JS; Lee, KW; Lee, YG; Oh, DY; Shin, DY | 1 |
Choi, HK; Hyun, SH; Kim, DH; Kim, JY; Kim, SH; Lee, SG; Lim, SR; Moon, KS; Park, SJ; Sul, D | 1 |
Alqahtani, S; Ambudkar, SV; Anreddy, N; Chen, ZS; Kaddoumi, A; Patel, BA; Shukla, S; Singh, S; Talele, TT; Wang, YJ; Zhang, GN; Zhang, YK | 1 |
Dall'Angelo, S; De Cesare, M; Folini, M; Frigerio, M; Lazzari, P; Manca, I; Sani, M; Spiga, M; Testa, A; Usai, I; Zaffaroni, N; Zanda, M; Zuco, V | 1 |
Bag, A; Bag, N | 1 |
Fernandez Mauleffinch, LM; Glenny, AM; Pavitt, S; Walsh, T | 1 |
Ageno, W; Appio, L; Brivio, L; Campiotti, L; Crowther, M; Dentali, F; Grandi, AM; Squizzato, A | 1 |
Blair, EY; Coakley, JC; Earl, JW; McLachlan, AJ; Nath, CE; Shaw, PJ; Stephen, K; Zeng, L | 1 |
Bode, AM; Cho, YY; Dong, Z; Malakhova, ML; Pugliese, A; Yao, K | 1 |
Fukuhara, T; Haseyama, Y; Hashino, S; Hirayama, Y; Iizuka, S; Ishida, T; Kaneda, M; Kobayashi, H; Kobayashi, R; Koda, K; Kurosawa, M; Masauji, N; Matsunaga, T; Mori, A; Mukai, M; Nishio, M; Noto, S; Onozawa, M; Ota, S; Sakai, H; Suzuki, N; Takahashi, T; Tanaka, J; Torimoto, Y; Yoshida, M | 1 |
Brocke, KS; Gebhardt, C; Ikonomidou, C; Luksch, H; Marzahn, J; Rzeski, W; Sifringer, M; Staufner, C; Stepulak, A; Turski, L; Uckermann, O | 1 |
Lee, T | 1 |
Dai, W; Li, RT; Liang, L; Lin, SW; Lu, JK; Xiang, Y; Yang, TY; Zhang, Q; Zhang, Y | 1 |
Abboud, CN; Ifthikharuddin, JJ; Lancet, JE; Liesveld, JL; Nichols, D; Oliva, J; Stamm, CG; Wedow, LA | 1 |
Broun, ER; DeVoe, M; Eisen, D; Essell, J; Sigmund, D | 1 |
Fernández, A | 1 |
MICHEL, R; ROCHE, J | 1 |
GENTY, N; MELONI, GA; VENDRELY, R | 1 |
Baar, C; Dale, O; Kaasa, S; Klepstad, P; Krokan, HE; Kvam, TM; Rakvåg, TT; Skorpen, F | 1 |
Brownlow, N; Dibb, NJ; Domin, J; Taylor, JR | 1 |
Fojo, T | 1 |
Hagen, K; Pettersen, E; Skorpen, F; Stovner, LJ; Zwart, JA | 1 |
Eley, HL; Russell, ST; Tisdale, MJ | 1 |
Bidart, JM; Boige, V; Delaloge, S; Le Couedic, JP; Motté, N; Pautier, P; Saulnier, P; Soria, JC; Vainchenker, W; Villeval, JL | 1 |
de Bree, PK; Kamerling, JP; van Gennip, AH; Wadman, SK | 1 |
Fasco, MJ; Guengerich, FP; Huang, L; Kaminsky, LS; Zhang, ZY | 1 |
Törnqvist, M | 1 |
Creek, KE; Liao, J; Pirisi, L; Xu, X | 1 |
Batter, S; Casey, D; Febbo, PG; Giovannucci, E; Hennekens, CH; Kantoff, PW; Platz, EA; Stampfer, MJ | 1 |
Lavelle, F | 1 |
Höglund, M; Ljungman, P; Weller, S | 1 |
Doi, H; Komatsu, H; Nishihira, T; Satomi, S | 1 |
Goto, M; Ichihara, A; Shinno, H | 1 |
Bojan, O; Kiricuta, I | 1 |
Fuska, J; Fusková, A; Proksa, B | 1 |
Hamaguchi, M; Nagata, K; Nozawa, Y; Okano, Y; Suzuki, T | 1 |
Attewell, R; Hagmar, L; Lindén, K; Osterman-Golkar, S; Törnqvist, M; Welinder, H | 1 |
Matsumoto, H; Mori, S | 1 |
Lalaiants, IE; Milovanova, LS | 1 |
Aoki, H; Fujii, J; Fukui, S; Hayasaka, H; Ikeyama, A; Mizushima, Y; Suzuki, Y; Taki, K | 1 |
Hisada, K; Mori, H; Shiba, K | 1 |
Carney, WP; Cooper, G; Hamer, P; Lefebvre, M; Petit, D; Rabin, H; Wolfe, H | 1 |
Hammond, WG; Landel, AM; Meguid, MM | 1 |
Warren, L | 1 |
Hahn, GM; Little, JB | 1 |
Andrews, NC; Aust, JB; Lawton, RL; Schroeder, JM | 1 |
Hahn, K; Jesdinsky, HJ; Ladner, HA | 1 |
Prager, MD | 1 |
Kellen, JA; Lustig, V | 1 |
Björnesjö, KB | 1 |
8 review(s) available for valine and Neoplasms
Article | Year |
---|---|
PARP-1 Val762Ala polymorphism and risk of cancer: a meta-analysis based on 39 case-control studies.
Topics: Alanine; Case-Control Studies; Genetic Predisposition to Disease; Humans; Neoplasms; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Polymorphism, Genetic; Valine | 2014 |
Target sequence polymorphism of human manganese superoxide dismutase gene and its association with cancer risk: a review.
Topics: Alanine; Alleles; Antioxidants; Breast Neoplasms; Genetic Predisposition to Disease; Humans; Neoplasms; Polymorphism, Genetic; Superoxide Dismutase; Valine | 2008 |
Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer.
Topics: Acyclovir; Antiviral Agents; Herpes Labialis; Humans; Immunocompromised Host; Neoplasms; Prostaglandins E; Randomized Controlled Trials as Topic; Simplexvirus; Stomatitis, Herpetic; Valacyclovir; Valine | 2009 |
JAK2V617F mutation for the early diagnosis of Ph- myeloproliferative neoplasms in patients with venous thromboembolism: a meta-analysis.
Topics: Algorithms; Amino Acid Substitution; Biomarkers, Tumor; Case-Control Studies; Early Detection of Cancer; Female; Gene Frequency; Humans; Janus Kinase 2; Male; Myeloproliferative Disorders; Neoplasms; Phenylalanine; Philadelphia Chromosome; Point Mutation; Valine; Venous Thromboembolism | 2009 |
[ON VARIOUS USES OF RADIOIODINE IN PHYSIOLOGY AND IN THYROID BIOCHEMISTRY].
Topics: Adenosine Triphosphate; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography; Cystine; Diiodotyrosine; Dogs; Glucuronates; Iodine Isotopes; Iodine Radioisotopes; Kidney; Leucine; Liver; Metabolism; Mitochondria; Neoplasms; Rats; Research; Sodium Isotopes; Sulfur Isotopes; Thyroid Gland; Thyroid Hormones; Thyroidectomy; Thyroxine; Triiodothyronine; Valine | 1963 |
Ethylene oxide as a biological reactive intermediate of endogenous origin.
Topics: Animals; Ethylene Oxide; Hemoglobins; Humans; Neoplasms; Reactive Oxygen Species; Valine | 1996 |
[Anti-cancer therapy with amino acid imbalance].
Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine | 2001 |
Aspects of amino acid and protein metabolism in cancer-bearing states.
Topics: Adenosine Triphosphate; Adult; Amino Acids; Amino Acids, Branched-Chain; Animals; Body Weight; Brain; Carcinoma 256, Walker; Clinical Trials as Topic; Humans; Leucine; Liver; Muscles; Neoplasms; Nutrition Disorders; Parenteral Nutrition, Total; Proteins; Rats; Tryptophan; Tyrosine; Valine | 1985 |
9 trial(s) available for valine and Neoplasms
Article | Year |
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Phase I and pharmacokinetic study of the vascular-disrupting agent CKD-516 (NOV120401) in patients with refractory solid tumors.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Benzophenones; Female; Humans; Male; Middle Aged; Neoplasms; Treatment Outcome; Valine; Young Adult | 2020 |
A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amyloid Precursor Protein Secretases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Tetrahydronaphthalenes; Treatment Outcome; Valine | 2015 |
Phase I Study of CKD-516, a Novel Vascular Disrupting Agent, in Patients with Advanced Solid Tumors.
Topics: Adult; Aged; Antineoplastic Agents; Benzophenones; Blood Vessels; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Valine | 2016 |
Oral valacyclovir versus intravenous acyclovir in preventing herpes simplex virus infections in autologous stem cell transplant recipients.
Topics: Acyclovir; Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Female; Herpes Simplex; Humans; Injections, Intravenous; Male; Middle Aged; Neoplasms; Stem Cell Transplantation; Valacyclovir; Valine | 2002 |
Clinical utility of oral valacyclovir compared with oral acyclovir for the prevention of herpes simplex virus mucositis following autologous bone marrow transplantation or stem cell rescue therapy.
Topics: Acyclovir; Administration, Oral; Adult; Biological Availability; Bone Marrow Transplantation; Female; Herpes Simplex; Humans; Male; Middle Aged; Neoplasms; Patient Selection; Stem Cell Transplantation; Transplantation, Autologous; Valacyclovir; Valine | 2003 |
The V89L polymorphism in the 5alpha-reductase type 2 gene and risk of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Anticarcinogenic Agents; Aspirin; beta Carotene; Boston; Double-Blind Method; Heart Diseases; Humans; Isoenzymes; Leucine; Male; Middle Aged; Neoplasms; Polymorphism, Genetic; Prostatic Neoplasms; Risk Factors; Valine; White People | 1999 |
Comparable aciclovir exposures produced by oral valaciclovir and intravenous aciclovir in immunocompromised cancer patients.
Topics: Acyclovir; Administration, Oral; Adolescent; Adult; Aged; Antiviral Agents; Female; Herpes Simplex; Humans; Immunocompromised Host; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Opportunistic Infections; Valacyclovir; Valine | 2001 |
Aspects of amino acid and protein metabolism in cancer-bearing states.
Topics: Adenosine Triphosphate; Adult; Amino Acids; Amino Acids, Branched-Chain; Animals; Body Weight; Brain; Carcinoma 256, Walker; Clinical Trials as Topic; Humans; Leucine; Liver; Muscles; Neoplasms; Nutrition Disorders; Parenteral Nutrition, Total; Proteins; Rats; Tryptophan; Tyrosine; Valine | 1985 |
Clinical note. Phase II study of 1-aminocyclopentanecarboxylic acid (NSC-1026) in patients with cancer.
Topics: Amino Acids; Clinical Trials as Topic; Colonic Neoplasms; Cyclopentanes; Evaluation Studies as Topic; Feeding and Eating Disorders; Head and Neck Neoplasms; Humans; Leiomyosarcoma; Male; Neoplasms; Rectal Neoplasms; Sarcoma; Testicular Neoplasms; Valine; Vomiting | 1970 |
49 other study(ies) available for valine and Neoplasms
Article | Year |
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Cancer Risk of Angiotensin II Receptor Blocker Valsartan: A Population-based Study.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Neoplasms; Tetrazoles; Valine; Valsartan | 2022 |
Non-cell-autonomous migration of RasV12-transformed cells towards the basal side of surrounding normal cells.
Topics: Amino Acid Sequence; Animals; Cell Movement; Cells, Cultured; Dogs; Humans; Mutation; Neoplasms; Nonmuscle Myosin Type IIA; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Rats; Signal Transduction; Valine | 2021 |
Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells.
Topics: Amino Acid Motifs; Cell Line, Tumor; Codon; Epithelial-Mesenchymal Transition; Glycine; Humans; Leucine; Neoplasms; Protein Biosynthesis; RNA, Transfer, Gly; RNA, Transfer, Leu; RNA, Transfer, Val; Signal Transduction; Valine; Zinc Finger E-box Binding Homeobox 2; Zinc Finger E-box-Binding Homeobox 1 | 2017 |
Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Citrulline; Cohort Studies; Female; Humans; Immunoconjugates; Male; Middle Aged; Models, Biological; Neoplasms; Oligopeptides; Valine; Young Adult | 2017 |
Co-occurring Genomic Alterations and Association With Progression-Free Survival in BRAFV600-Mutated Nonmelanoma Tumors.
Topics: Amino Acid Substitution; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Genetic Association Studies; Humans; Molecular Targeted Therapy; Mutation; Neoplasms; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Valine | 2017 |
Sofosbuvir-Based Therapy in Hepatitis C Virus-Infected Cancer Patients: A Prospective Observational Study.
Topics: Aged; Antiviral Agents; Benzimidazoles; Breast Neoplasms; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Fluorenes; Head and Neck Neoplasms; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Interferons; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Neoplasms; Polyethylene Glycols; Prospective Studies; Pyrrolidines; Ribavirin; Simeprevir; Sofosbuvir; Sustained Virologic Response; Valine | 2019 |
Novel biosurfactant and lipid core-shell type nanocapsular sustained release system for intravenous application of methotrexate.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Cell Survival; Delayed-Action Preparations; Drug Liberation; Erythrocytes; Female; Hemolysis; Humans; Lipids; MCF-7 Cells; Methotrexate; Mice; Nanoparticles; Neoplasms; Rats, Sprague-Dawley; Surface-Active Agents; Tumor Burden; Valine | 2019 |
The effects of Arctigenin-Valine ester on chemotherapy-induced myelosuppression in mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Cell Cycle Checkpoints; Cytokines; Furans; Hematopoietic Stem Cells; Lignans; Male; Mice; Mice, Inbred BALB C; Neoplasms; Valine | 2019 |
Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody-Drug Conjugates.
Topics: Body Weight; Citrulline; Clinical Trials as Topic; Drug Dosage Calculations; Female; Humans; Immunoconjugates; Male; Models, Biological; Neoplasms; Oligopeptides; Peripheral Nervous System Diseases; Time Factors; Valine | 2019 |
CKD-516 displays vascular disrupting properties and enhances anti-tumor activity in combination with chemotherapy in a murine tumor model.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzophenones; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Deoxycytidine; Female; Gemcitabine; Human Umbilical Vein Endothelial Cells; Humans; Mice, Mutant Strains; Microtubules; Neoplasms; Neovascularization, Pathologic; Tubulin; Tumor Burden; Valine; Xenograft Model Antitumor Assays | 2014 |
[Plasma amino acid profiling of "same symptom for different disease" in Uyghur medicine based on high-performance liquid chromatography].
Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Cystine; Humans; Isoleucine; Leucine; Medicine, Chinese Traditional; Neoplasms; Serine; Tyrosine; Valine | 2014 |
New, tolerable γ-secretase inhibitor takes desmoid down a notch.
Topics: Amyloid Precursor Protein Secretases; Enzyme Inhibitors; Female; Humans; Male; Neoplasms; Tetrahydronaphthalenes; Valine | 2015 |
Potential urinary biomarkers of nephrotoxicity in cyclophosphamide-treated rats investigated by NMR-based metabolic profiling.
Topics: Animals; Biomarkers; Cyclophosphamide; Humans; Isoleucine; Kidney; Leucine; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolomics; Neoplasms; Rats; Taurine; Valine | 2017 |
Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Drug Resistance, Multiple; Heterografts; Humans; Mice; Neoplasm Transplantation; Neoplasms; Paclitaxel; Peptidomimetics; Thiazoles; Treatment Outcome; Valine | 2017 |
Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Mice; Microscopy, Fluorescence; Neoplasms; Paclitaxel; Structure-Activity Relationship; Transplantation, Heterologous; Tubulin; Tubulin Modulators; Valine; Vinblastine; Vinorelbine | 2017 |
Population pharmacokinetics of acyclovir in children and young people with malignancy after administration of intravenous acyclovir or oral valacyclovir.
Topics: Acyclovir; Administration, Oral; Antiviral Agents; Humans; Infant; Infusions, Intravenous; Neoplasms; Prospective Studies; Valacyclovir; Valine | 2009 |
A regulatory mechanism for RSK2 NH(2)-terminal kinase activity.
Topics: Binding Sites; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Kaempferols; Kinetics; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Recombinant Proteins; Reference Values; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Valine | 2009 |
Incidence and risk of postherpetic neuralgia after varicella zoster virus infection in hematopoietic cell transplantation recipients: Hokkaido Hematology Study Group.
Topics: Acyclovir; Adolescent; Adult; Aged; Chickenpox; Child; Child, Preschool; Female; Genetic Diseases, Inborn; Hematopoietic Stem Cell Transplantation; Herpes Zoster; Humans; Incidence; Infant; Infant, Newborn; Japan; Male; Middle Aged; Neoplasms; Neuralgia, Postherpetic; Postoperative Complications; Retrospective Studies; Risk; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valine; Virus Activation; Young Adult | 2009 |
Expression of glutamate receptor subunits in human cancers.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Brain; Cell Line, Tumor; Excitatory Amino Acid Antagonists; Humans; Neoplasms; Patch-Clamp Techniques; Protein Subunits; Receptors, AMPA; Receptors, Metabotropic Glutamate; Valine | 2009 |
Ask the doctor. I read that angiotensin-receptor blockers cause cancer. I take one (Diovan) for my blood pressure. Should I stop?
Topics: Angiotensin II Type 1 Receptor Blockers; Health Knowledge, Attitudes, Practice; Humans; Neoplasms; Risk Assessment; Tetrazoles; Valine; Valsartan | 2010 |
Novel cathepsin B-sensitive paclitaxel conjugate: Higher water solubility, better efficacy and lower toxicity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cathepsin B; Cell Cycle; Cell Line, Tumor; Citrulline; Dipeptides; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Polyethylene Glycols; Tumor Burden; Valine | 2012 |
Oncogenic mutations and packing defects in protein structure.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Glycine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Mutation; Neoplasms; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins p21(ras); Static Electricity; Tumor Suppressor Protein p53; Valine | 2003 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.
Topics: Aged; Catechol O-Methyltransferase; Dose-Response Relationship, Drug; Female; Genotype; Humans; Male; Methionine; Middle Aged; Morphine; Narcotics; Neoplasms; Pain; Pain Measurement; Pain Threshold; Pharmacogenetics; Polymorphism, Genetic; Retrospective Studies; Statistics, Nonparametric; Valine | 2005 |
FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Benzamides; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Inflammation; Inhibitory Concentration 50; Macrophage Colony-Stimulating Factor; Mice; Mutation; Neoplasms; Oncogene Protein v-cbl; Phosphorylation; Piperazines; Protein Structure, Tertiary; Proto-Oncogene Proteins c-crk; Proto-Oncogene Proteins c-kit; Pyrimidines; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Signal Transduction; Time Factors; Valine | 2006 |
Can mutations in gamma-actin modulate the toxicity of microtubule targeting agents?
Topics: Actins; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Leucine; Microtubules; Mutation; Neoplasms; Proline; RNA, Small Interfering; Tubulin; Tubulin Modulators; Valine; Vincristine | 2006 |
The impact of the catechol-O-methyltransferase Val158Met polymorphism on survival in the general population--the HUNT study.
Topics: Cardiovascular Diseases; Catechol O-Methyltransferase; Diabetes Mellitus; Female; Follow-Up Studies; Genotype; Humans; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Genetic; Survival Analysis; Valine | 2007 |
Effect of branched-chain amino acids on muscle atrophy in cancer cachexia.
Topics: Adaptor Proteins, Signal Transducing; Amino Acids, Branched-Chain; Animals; Cachexia; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Eukaryotic Initiation Factors; Leucine; Mice; Mice, Inbred Strains; Muscular Atrophy; Myoblasts; Neoplasms; Phosphoproteins; Phosphorylation; Protein Kinases; Proteoglycans; Time Factors; Valine | 2007 |
Mutations in JAK2V617F homologous domain of JAK genes are uncommon in solid tumors.
Topics: Base Sequence; Conserved Sequence; Humans; Janus Kinase 2; Mutation; Neoplasms; Phenylalanine; Protein Structure, Tertiary; Valine | 2007 |
Linear relationship between the R- and S-enantiomers of a beta-aminoisobutyric acid in human urine.
Topics: Adolescent; Aminoisobutyric Acids; Child; Child, Preschool; Humans; Infant; Leukemia, Lymphoid; Models, Biological; Neoplasms; Stereoisomerism; Thymine; Valine | 1981 |
Characterization of purified human recombinant cytochrome P4501A1-Ile462 and -Val462: assessment of a role for the rare allele in carcinogenesis.
Topics: Alleles; Base Sequence; Cytochrome P-450 Enzyme System; DNA, Complementary; Escherichia coli; Humans; Isoenzymes; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasms; Plasmids; Recombinant Proteins; Valine; Warfarin | 1996 |
Human keratinocytes and tumor-derived cell lines express alternatively spliced forms of transforming growth factor-alpha mRNA, encoding precursors lacking carboxyl-terminal valine residues.
Topics: Amino Acid Substitution; Animals; Calcimycin; Calcium; CHO Cells; Cricetinae; Cricetulus; Exons; Humans; Introns; Ionophores; Keratinocytes; Molecular Sequence Data; Neoplasms; Protein Processing, Post-Translational; Recombinant Fusion Proteins; RNA Splicing; RNA, Messenger; RNA, Neoplasm; Serine Endopeptidases; Transforming Growth Factor alpha; Tumor Cells, Cultured; Valine | 1999 |
[Telomerases: transformation trial!].
Topics: Alanine; Antineoplastic Agents; Aspartic Acid; Catalytic Domain; Cell Division; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Isoleucine; Neoplasms; RNA; Telomerase; Transformation, Genetic; Tumor Cells, Cultured; Valine | 1999 |
Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Female; Fetus; Humans; In Vitro Techniques; Isoenzymes; Isoleucine; Kidney Neoplasms; Leucine; Liver Neoplasms; Male; Neoplasms; Rats; Species Specificity; Stomach Neoplasms; Substrate Specificity; Tissue Distribution; Transaminases; Valine | 1977 |
Differences in uptake of aminoacids by patients with various forms of cancer.
Topics: Amino Acids; Female; Humans; Lysine; Male; Neoplasm Metastasis; Neoplasms; Valine | 1978 |
New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; In Vitro Techniques; Leukemia; Neoplasms; RNA, Neoplasm; Sarcoma; Thymidine; Uridine; Valine; Xanthenes; Xanthones | 1975 |
Characterization of a Gly19-->Val mutant of ram p25, a low Mr GTP-binding protein: loss of GTP/GDP-binding activity in the mutated ram p25.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Escherichia coli; Genes, ras; Glycine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Multigene Family; Mutagenesis, Site-Directed; Neoplasms; Oligodeoxyribonucleotides; Peptide Fragments; rab GTP-Binding Proteins; rab27 GTP-Binding Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Trypsin; Valine | 1992 |
An epidemiological study of cancer risk among workers exposed to ethylene oxide using hemoglobin adducts to validate environmental exposure assessments.
Topics: Adult; Aged; Cohort Studies; Environmental Monitoring; Epidemiological Monitoring; Ethylene Oxide; Female; Hemoglobins; Humans; Male; Middle Aged; Morbidity; Neoplasms; Occupational Diseases; Occupational Exposure; Risk Factors; Valine | 1991 |
[Anticancer therapy with amino acid imbalance].
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine | 1991 |
[The role of "valine substitution" in oncogene functioning (a hypothesis)].
Topics: Anemia, Sickle Cell; GTP Phosphohydrolases; Humans; In Vitro Techniques; Malaria; Models, Molecular; Neoplasms; Oncogene Protein p21(ras); Oncogenes; Peptide Chain Initiation, Translational; Peptide Chain Termination, Translational; Valine; X-Ray Diffraction | 1991 |
[A clinical study of amino acid metabolism in cancerous hypoproteinemia--the role of branched chain amino acids (BCAA) and appropriate compositions of BCAA in parenteral nutrition].
Topics: Amino Acids; Amino Acids, Branched-Chain; Female; Humans; Hypoproteinemia; Isoleucine; Leucine; Male; Middle Aged; Neoplasms; Nitrogen; Parenteral Nutrition, Total; Prealbumin; Retinol-Binding Proteins; Transferrin; Valine | 1989 |
Analogues of alpha-aminoisobutyric acid with various alkyl groups as potential tumour imaging agents; effects of chain length on tumour and normal tissue specificity.
Topics: Aminobutyrates; Aminoisobutyric Acids; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Mice; Neoplasms; Radionuclide Imaging; Structure-Activity Relationship; Tissue Distribution; Valine | 1989 |
A monoclonal antibody reactive with an activated ras protein expressing valine at position 12.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; Humans; Immunoenzyme Techniques; Immunosorbent Techniques; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutation; Neoplasms; Oncogenes; Proto-Oncogene Proteins; Urinary Bladder Neoplasms; Valine | 1986 |
The biological significance of turnover of the surface membrane of animal cells.
Topics: Adenoviridae; Animals; Carbon Isotopes; Carcinoma; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Depression, Chemical; Glucosamine; Glucose; In Vitro Techniques; L Cells; Leucine; Mice; Mitosis; Mouth Neoplasms; Neoplasms; Simian virus 40; Surface Properties; Valine; Vinblastine | 1969 |
Plateau-phase cultures of mammalian cells: an in vitro model for human cancer.
Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Contact Inhibition; Cricetinae; Culture Media; DNA; Humans; Leucine; Liver; Mitosis; Models, Biological; Neoplasms; Proteins; Radiation-Sensitizing Agents; RNA; Sulfhydryl Compounds; Thymidine; Time Factors; Tritium; Uridine; Valine | 1972 |
[Concentration changes of free amino acids in blood plasma of patients under radiotherapy. (With reference to statistical results)].
Topics: Alanine; Amino Acids; Bronchial Neoplasms; Carcinoma; Cobalt Isotopes; Dysgerminoma; Esophageal Neoplasms; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leucine; Male; Neoplasms; Phenylalanine; Proline; Radiation Injuries; Sex Factors; Statistics as Topic; Tyrosine; Urinary Bladder Neoplasms; Valine | 1972 |
Prediction of response to L-asparaginase therapy.
Topics: Animals; Asparaginase; Carbon Isotopes; Cell Line; Drug Resistance; Female; Humans; Leukemia; Lymphoma; Male; Mice; Neoplasms; Neoplasms, Experimental; Prognosis; Valine | 1971 |
Patterns of amino-acid inhibition of alkaline phosphatases as an aid in cancer diagnosis.
Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acids; Animals; Arginine; Colonic Neoplasms; Female; Humans; In Vitro Techniques; Isoenzymes; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms; Phenylalanine; Rats; Valine | 1971 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |