valine and HbS Disease

valine has been researched along with HbS Disease in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (74.19)	18.7374
1990's	2 (6.45)	18.2507
2000's	3 (9.68)	29.6817
2010's	3 (9.68)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bergendahl, LT; Esin, A; Marsh, JA; Savolainen, V; Warnecke, T	1
Becchi, M; Francina, A; Joly, P; Préhu, C; Riou, J; Wajcman, H; Zanella-Cleon, I	1
Billote, GB; Brittenham, GM; DeBellis, RH; Ender, KL; Erlanger, BF	1
Gali, E; Kaya, H; Oktar, S; Ozcelik, N; Sogut, S; Tutanc, M; Yigit, A; Yilmaz, HR; Yonden, Z	1
HEYWOOD, JD; KARON, M; WEISSMAN, S	1
Ferrone, FA; Roufberg, A	1
Acharya, AS; Ho, C; Ho, NT; Kumar, R; Malavalli, A; Manjula, BN; Nagel, RL; Prabhakaran, M; Rao, MJ; Sun, DP	1
Bechtel, KC; Haycraft, GL; Horne, MK; Jue, DL; Moo-Penn, WF; Nagel, RL; Roth, EF; Schmidt, RM; Wright, JM	1
Cottam, GL; Waterman, MR	1
Manning, JM; Nigen, AM	1
Kirson, LE; Tomaro, AJ	1
Pigoń, H	1
Yang, JT	1
Benjamin, LJ; Manning, JM; Ueno, H; Yatco, E	1
Lalaiants, IE; Milovanova, LS	1
Ben-Bassat, I; Beutler, E; Paniker, NV	1
Itano, HA; Suzuki, H	1
Anderson, WF	1
Cerami, A; Gillette, PN; Herbert, JT; Lu, YS; Peterson, CM	1
Rieder, RF	1
Cerami, A	1
Cerami, A; Gillette, PN; Lee, CK; Manning, JM	1
Lee, CK; Manning, JM	1
Moon, RB; Nelson, MJ; Powars, DF; Richards, JH	1
Cerami, A; Gillette, PN; Manning, JM	1
Camp, FR; Henry, RL; Nalbandian, RM; Nichols, BM; Wolf, PL	1
Ranney, HM	1
Itano, HA; Kazazian, HH	1
Beale, D; Lehmann, H; Marengo-Rowe, AJ	1
Heywood, D; Karon, M; Weissman, S	1
Murayama, M	1

Reviews

4 review(s) available for valine and HbS Disease

Article	Year
Molecular aspects of sickle cell disease. Angewandte Chemie (International ed. in English), 1976, Volume: 15, Issue:12 Topics: Anemia, Sickle Cell; Electron Spin Resonance Spectroscopy; Erythrocytes; Gels; Glutamates; Hemoglobin A; Hemoglobin, Sickle; Kinetics; Macromolecular Substances; Microscopy, Electron; Oxygen; Protein Conformation; Thermodynamics; Valine; X-Ray Diffraction	1976
[Sickle cell anemia--a world problem]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1975, Feb-17, Volume: 30, Issue:7 Topics: Anemia, Sickle Cell; Blood Coagulation; Blood Viscosity; Erythrocyte Aging; Female; Hemoglobins; Heterozygote; Homozygote; Humans; Male; Maternal-Fetal Exchange; Mutation; Phenotype; Pregnancy; Pregnancy Complications; Valine	1975
Variation in beta-alpha synthesis ratios in thalassemia and hemoglobinopathies. Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0 Topics: Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Erythrocyte Aging; Erythrocytes; Globins; Hemoglobin C Disease; Hemoglobinopathies; Heterozygote; Homozygote; Humans; Leucine; Peptide Chain Termination, Translational; Peptide Fragments; RNA, Messenger; Thalassemia; Tritium; Trypsin; Valine	1974
Review of the development of cyanate as a drug in the treatment of sickle cell anemia. Annals of the New York Academy of Sciences, 1974, Nov-29, Volume: 241, Issue:0 Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Bilirubin; Binding Sites; Carbon Dioxide; Carbon Radioisotopes; Cell Survival; Chromium; Cyanates; Erythrocytes; Female; Hematocrit; Hemoglobins; Humans; L-Lactate Dehydrogenase; Male; Mice; Organ Specificity; Oxygen; Protein Binding; Time Factors; Valine	1974

Trials

2 trial(s) available for valine and HbS Disease

Article	Year
Safety of short-term valacyclovir as an anti-sickling agent in sickle-cell anemia. Pediatric blood & cancer, 2011, Volume: 56, Issue:5 Topics: Acyclovir; Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Antiviral Agents; Erythrocytes, Abnormal; Female; Hemoglobins; Humans; Male; Maximum Tolerated Dose; Prodrugs; Prospective Studies; Safety; Survival Rate; Treatment Outcome; Valacyclovir; Valine; Young Adult	2011
Studies with intravenous sodium cyanate in patients with sickle cell anemia. The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3 Topics: Adolescent; Adult; Amino Acids; Anemia, Sickle Cell; Blood Cell Count; Chromatography, Gas; Clinical Trials as Topic; Cyanates; Diuresis; Feeding and Eating Disorders; Female; Hemoglobins; Humans; Hydantoins; Injections, Intravenous; Male; Middle Aged; Reticulocytes; Thyrotropin; Time Factors; Valine; Vasopressins	1974

Article

Year

Safety of short-term valacyclovir as an anti-sickling agent in sickle-cell anemia.

Pediatric blood & cancer, 2011, Volume: 56, Issue:5

Topics: Acyclovir; Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Antiviral Agents; Erythrocytes, Abnormal; Female; Hemoglobins; Humans; Male; Maximum Tolerated Dose; Prodrugs; Prospective Studies; Safety; Survival Rate; Treatment Outcome; Valacyclovir; Valine; Young Adult

2011

Studies with intravenous sodium cyanate in patients with sickle cell anemia.

The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

Topics: Adolescent; Adult; Amino Acids; Anemia, Sickle Cell; Blood Cell Count; Chromatography, Gas; Clinical Trials as Topic; Cyanates; Diuresis; Feeding and Eating Disorders; Female; Hemoglobins; Humans; Hydantoins; Injections, Intravenous; Male; Middle Aged; Reticulocytes; Thyrotropin; Time Factors; Valine; Vasopressins

1974

Other Studies

25 other study(ies) available for valine and HbS Disease

Article	Year
The genetic basis and evolution of red blood cell sickling in deer. Nature ecology & evolution, 2018, Volume: 2, Issue:2 Topics: Amino Acid Sequence; Anemia, Sickle Cell; Animals; beta-Globins; Deer; Erythrocytes; Phylogeny; Polymorphism, Genetic; Sequence Alignment; Valine	2018
Strategy for identification by mass spectrometry of a new human hemoglobin variant with two mutations in Cis in the beta-globin chain: Hb S-Clichy [beta6(A3)Glu-->Val; beta8(A5)Lys-->Thr]. Hemoglobin, 2009, Volume: 33, Issue:3 Topics: Anemia, Sickle Cell; beta-Globins; Chromatography, Liquid; Female; Glutamic Acid; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Lysine; Mass Spectrometry; Middle Aged; Mutation; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Valine	2009
Ala-9Val polymorphism of Mn-SOD gene in sickle cell anemia. Genetics and molecular research : GMR, 2011, May-10, Volume: 10, Issue:2 Topics: Adolescent; Adult; Alanine; Alleles; Amino Acid Substitution; Anemia, Sickle Cell; Child; Child, Preschool; Female; Gene Frequency; Genetic Association Studies; Humans; Male; Oxidative Stress; Polymorphism, Genetic; Superoxide Dismutase; Valine	2011
AMINO ACIDS: INCORPORATION INTO ALPHA- AND BETA-CHAINS OF HEMOGLOBIN BY NORMAL AND THALASSEMIC RETICULOCYTES. Science (New York, N.Y.), 1964, Oct-23, Volume: 146, Issue:3643 Topics: Amino Acids; Anemia, Sickle Cell; Carbon Isotopes; Globins; Hemoglobins; Humans; Leucine; Leukemia; Proteins; Research; Reticulocytes; Thalassemia; Valine	1964
A model for the sickle hemoglobin fiber using both mutation sites. Protein science : a publication of the Protein Society, 2000, Volume: 9, Issue:5 Topics: Algorithms; Anemia, Sickle Cell; Computer Simulation; Hemoglobin, Sickle; Hemoglobins; Hemoglobinuria; Humans; Models, Biological; Models, Chemical; Mutagenesis, Site-Directed; Protein Binding; Valine	2000
Interspecies hybrid HbS: complete neutralization of Val6(beta)-dependent polymerization of human beta-chain by pig alpha-chains. Journal of molecular biology, 2000, Jul-28, Volume: 300, Issue:5 Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Anemia, Sickle Cell; Animals; Binding Sites; Dimerization; Genetic Therapy; Globins; Heme; Hemoglobin, Sickle; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Oxygen; Protein Engineering; Protein Structure, Quaternary; Recombinant Fusion Proteins; Static Electricity; Swine; Valine	2000
Hemoglobin S Travis: a sickling hemoglobin with two amino acid substitutions [beta6(A3)glutamic acid leads to valine and beta142 (h20) alanine leads to valine). European journal of biochemistry, 1977, Aug-01, Volume: 77, Issue:3 Topics: Alanine; Amino Acids; Anemia, Sickle Cell; Female; Genetic Variation; Glutamates; Hemoglobin, Sickle; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Oxygen; Pedigree; Peptide Fragments; Valine	1977
Inhibition of erythrocyte sickling in vitro by DL-glyceraldehyde. Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:1 Topics: Anemia, Sickle Cell; Erythrocytes, Abnormal; Gels; Glyceraldehyde; Hemoglobin, Sickle; Humans; Lysine; Oxygen; Valine	1977
Mental nerve paresthesia secondary to sickle-cell crisis. Oral surgery, oral medicine, and oral pathology, 1979, Volume: 48, Issue:6 Topics: Adolescent; Adult; Anemia, Sickle Cell; Hemoglobins; Humans; Lip; Male; Mandibular Nerve; Paresthesia; Thalassemia; Valine	1979
Intermolecular contacts of deoxyhemoblogin S: a hypothesis and search for possible anti-sickling agents. Biochemical and biophysical research communications, 1975, Mar-03, Volume: 63, Issue:1 Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Binding Sites; Glutamates; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Macromolecular Substances; Models, Biological; Protein Binding; Protein Conformation; Valine	1975
Effects of methyl acetyl phosphate, a covalent antisickling agent, on the density profiles of sickle erythrocytes. The Journal of laboratory and clinical medicine, 1992, Volume: 120, Issue:1 Topics: Anemia, Sickle Cell; Antisickling Agents; Cell Fractionation; Cell Separation; Centrifugation, Density Gradient; Erythrocyte Count; Erythrocytes, Abnormal; Hemoglobin, Sickle; Humans; Oxygen; Phosphonoacetic Acid; Valine	1992
[The role of "valine substitution" in oncogene functioning (a hypothesis)]. Voprosy onkologii, 1991, Volume: 37, Issue:2 Topics: Anemia, Sickle Cell; GTP Phosphohydrolases; Humans; In Vitro Techniques; Malaria; Models, Molecular; Neoplasms; Oncogene Protein p21(ras); Oncogenes; Peptide Chain Initiation, Translational; Peptide Chain Termination, Translational; Valine; X-Ray Diffraction	1991
Evaluation of sickle hemoglobin and desickling agents by falling ball viscometry. The Journal of laboratory and clinical medicine, 1972, Volume: 80, Issue:2 Topics: 6-Phytase; Anemia, Sickle Cell; Aspirin; Blood Viscosity; Carbamates; Cyanates; Drug Storage; Fructose; Glyceraldehyde; Glyceric Acids; Hemoglobins, Abnormal; Humans; Inositol; Methemoglobin; NAD; Phosphoric Acids; Potassium; Pyridoxal Phosphate; Time Factors; Urea; Valine; Vinblastine	1972
Delayed removal of N-terminal methionine from nascent globin chains in sickle-cell anemia reticulocytes. Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:7 Topics: Anemia, Sickle Cell; Animals; Chromatography; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; In Vitro Techniques; Lysine; Methionine; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptides; Rabbits; Reticulocytes; Sulfur Isotopes; Tritium; Valine	1973
Isolation and translation of messenger RNA from beta-thalassemia red cells. Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0 Topics: Anemia; Anemia, Sickle Cell; Animals; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Erythroblastosis, Fetal; Erythrocytes; Female; Globins; Glycine; Humans; Leucine; Methionine; Peptide Fragments; Peptide Initiation Factors; Phenylhydrazines; Pregnancy; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; RNA, Transfer; Thalassemia; Valine	1974
Gas chromatographic determination of the carbamylation of hemoglobin S by cyanate. The Journal of laboratory and clinical medicine, 1973, Volume: 81, Issue:6 Topics: Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Chromatography, Gas; Cyanates; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Hydantoins; Methods; Time Factors; Valine	1973
Kinetics of the carbamylation of the amino groups of sickle cell hemoglobin by cyanate. The Journal of biological chemistry, 1973, Aug-25, Volume: 248, Issue:16 Topics: Anemia, Sickle Cell; Binding, Competitive; Carbamates; Carbon Dioxide; Carbon Isotopes; Carboxyhemoglobin; Countercurrent Distribution; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Hemolysis; Humans; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Oxyhemoglobins; Peptides; Potassium; Sodium; Trypsin; Valine	1973
13C magnetic resonance studies of hemoglobin carbamylation. Physiological chemistry and physics, 1974, Volume: 6, Issue:1 Topics: Adult; Amino Acid Sequence; Anemia, Sickle Cell; Binding Sites; Carbon Isotopes; Carbon Monoxide; Carboxyhemoglobin; Cyanates; Evaluation Studies as Topic; Fourier Analysis; Hemoglobins; Heparin; Humans; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Methods; Protein Binding; Protein Conformation; Valine	1974
Increased survival of sickle-cell erythrocytes after treatment in vitro with sodium cyanate. Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:11 Topics: Adolescent; Adult; Anemia, Sickle Cell; Chromium Isotopes; Cyanates; Erythrocytes; Erythrocytes, Abnormal; Female; Half-Life; Hemoglobins; Humans; In Vitro Techniques; Male; Time Factors; Valine	1971
Molecular basis for a simple, specific test for S hemoglobin: the Murayama test. Clinical chemistry, 1970, Volume: 16, Issue:11 Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Child; Child, Preschool; Female; Gels; Glutamates; Hemoglobin C; Hemoglobins, Abnormal; Heterozygote; Homozygote; Humans; Male; Methods; Middle Aged; Models, Structural; Temperature; Valine	1970
Interactions of other hemoglobin variants with sickle-cell hemoglobin. The New England journal of medicine, 1970, Dec-24, Volume: 283, Issue:26 Topics: Anemia, Sickle Cell; Binding Sites; Gels; Glutamates; Hemoglobin C; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Models, Theoretical; Oxygen; Polymers; Valine	1970
Studies on the quantitative control of polypeptide synthesis in human reticulocytes. The Journal of biological chemistry, 1968, Apr-25, Volume: 243, Issue:8 Topics: Anemia, Sickle Cell; Carbon Isotopes; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; In Vitro Techniques; Leucine; Male; Peptide Biosynthesis; Reticulocytes; RNA, Messenger; Time Factors; Trypsin; Valine	1968
New human haemoglobin variant from southern Arabia: G-Audhali (alpha-23(B4) glutamic acid--valine) and the variability of B4 in human haemoglobin. Nature, 1968, Sep-14, Volume: 219, Issue:5159 Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Arabia; Blood Protein Electrophoresis; Chymotrypsin; Glutamates; Hemoglobins, Abnormal; Humans; Peptides; Thalassemia; Trypsin; Valine	1968
Asymmetrical incorporation of amino acids in the alpha and beta chains of hemoglobin synthesized by thalassemic reticulocytes. The Journal of laboratory and clinical medicine, 1965, Volume: 66, Issue:3 Topics: Anemia, Sickle Cell; Dinitrophenols; Hemoglobins; Humans; In Vitro Techniques; Leucine; Leukemia, Lymphoid; Peptide Biosynthesis; Reticulocytes; Thalassemia; Valine	1965
Tertiary structure of sickle cell hemoglobin and its functional significance. Journal of cellular physiology, 1966, Volume: 67, Issue:3 Topics: Amino Acid Sequence; Anemia, Sickle Cell; Erythrocytes; Glutamates; Hemoglobins, Abnormal; Humans; Methane; Microscopy, Electron; Models, Theoretical; Temperature; Valine	1966