uric acid has been researched along with Malaria in 8 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid is an important contributor to inflammatory cytokine secretion, dendritic cell and T cell responses induced by Plasmodium, suggesting uric acid as a novel molecular target for anti-inflammatory therapies in malaria." | 6.50 | A surprising role for uric acid: the inflammatory malaria response. ( Gallego-Delgado, J; Orengo, JM; Rodriguez, A; Ty, M; van de Hoef, D, 2014) |
| "Elevated uric acid (UA) levels have been reported in malaria patients and are particularly prominent in severe malaria cases." | 5.41 | Association of uric acid levels with severity of Plasmodium infections: a systematic review and meta-analysis. ( Kotepui, KU; Kotepui, M; Kuraeiad, S; Mahittikorn, A; Masangkay, FR, 2023) |
| "The finding of this study showed that khat use was strongly associated with increment of levels of liver and kidney biomarkers, leucopenia, severe anemia, rise in level of inflammation biomarkers: C-reactive protein (CRP), uric acid (UA), increased monocyte-lymphocyte count ratio (MLCR), manifestation of cerebral malaria symptoms such as ataxia, paralysis and deviation of the head but with no pulmonary edema." | 3.81 | Effect of chronic khat (Catha edulis, Forsk) use on outcome of Plasmodium berghei ANKA infection in Swiss albino mice. ( Alemayehu, E; Ambelu, A; Ketema, T; Yohannes, M, 2015) |
| "Uric acid is an important contributor to inflammatory cytokine secretion, dendritic cell and T cell responses induced by Plasmodium, suggesting uric acid as a novel molecular target for anti-inflammatory therapies in malaria." | 2.50 | A surprising role for uric acid: the inflammatory malaria response. ( Gallego-Delgado, J; Orengo, JM; Rodriguez, A; Ty, M; van de Hoef, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Kuraeiad, S | 1 |
| Kotepui, KU | 1 |
| Masangkay, FR | 1 |
| Mahittikorn, A | 1 |
| Kotepui, M | 1 |
| Guermonprez, P | 1 |
| Helft, J | 1 |
| Claser, C | 1 |
| Deroubaix, S | 1 |
| Karanje, H | 1 |
| Gazumyan, A | 1 |
| Darasse-Jèze, G | 1 |
| Telerman, SB | 1 |
| Breton, G | 1 |
| Schreiber, HA | 1 |
| Frias-Staheli, N | 1 |
| Billerbeck, E | 1 |
| Dorner, M | 1 |
| Rice, CM | 1 |
| Ploss, A | 1 |
| Klein, F | 1 |
| Swiecki, M | 1 |
| Colonna, M | 1 |
| Kamphorst, AO | 1 |
| Meredith, M | 1 |
| Niec, R | 1 |
| Takacs, C | 1 |
| Mikhail, F | 1 |
| Hari, A | 1 |
| Bosque, D | 1 |
| Eisenreich, T | 1 |
| Merad, M | 1 |
| Shi, Y | 1 |
| Ginhoux, F | 1 |
| Rénia, L | 1 |
| Urban, BC | 1 |
| Nussenzweig, MC | 1 |
| Gallego-Delgado, J | 1 |
| Ty, M | 1 |
| Orengo, JM | 1 |
| van de Hoef, D | 1 |
| Rodriguez, A | 1 |
| Ketema, T | 1 |
| Yohannes, M | 1 |
| Alemayehu, E | 1 |
| Ambelu, A | 1 |
| Peterson, TM | 1 |
| Gow, AJ | 1 |
| Luckhart, S | 1 |
| Gupta, OK | 1 |
| Banerjee, RN | 1 |
| Stocker, R | 1 |
| Hunt, NH | 1 |
| Weidemann, MJ | 1 |
| Wellde, BT | 1 |
| Johnson, AJ | 1 |
| Williams, JS | 1 |
| Sadun, EH | 1 |
2 reviews available for uric acid and Malaria
| Article | Year |
|---|---|
Association of uric acid levels with severity of Plasmodium infections: a systematic review and meta-analysis.
Topics: Animals; Databases, Factual; Humans; Malaria; MEDLINE; Problem Solving; Sheep, Domestic; Uric Acid | 2023 |
A surprising role for uric acid: the inflammatory malaria response.
Topics: Animals; Erythrocytes; Host-Parasite Interactions; Humans; Inflammation; Inflammation Mediators; Mal | 2014 |
6 other studies available for uric acid and Malaria
| Article | Year |
|---|---|
Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection.
Topics: Animals; CD8 Antigens; Cell Movement; Dendritic Cells; Female; Humans; Interferon Type I; Malaria; M | 2013 |
Effect of chronic khat (Catha edulis, Forsk) use on outcome of Plasmodium berghei ANKA infection in Swiss albino mice.
Topics: Animals; Body Temperature; Brain; C-Reactive Protein; Catha; Disease Models, Animal; Female; Hemoglo | 2015 |
Nitric oxide metabolites induced in Anopheles stephensi control malaria parasite infection.
Topics: Allantoin; Animals; Anopheles; Dermatologic Agents; Dietary Supplements; Hemoglobins; Malaria; Mice; | 2007 |
Possible association of disseminated intravascular coagulation and hyperuricaemia with Plasmodium vivax malaria.
Topics: Adolescent; Adult; Child, Preschool; Disseminated Intravascular Coagulation; Female; Humans; Infant, | 1976 |
Antioxidants in plasma from mice infected with Plasmodium vinckei.
Topics: Animals; Antioxidants; Ascorbic Acid; Dehydroascorbic Acid; Malaria; Male; Mice; Mice, Inbred CBA; S | 1986 |
Experimental infection with Plasmodium falciparum in Aotus monkeys. I. Parasitologic, hematologic, and serum biochemical determinations.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Cell Count; Blood Glucose; Blood P | 1972 |