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uric acid and Autism

uric acid has been researched along with Autism in 8 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"A subclass of patients with classic infantile autism have uric acid excretion which is >2 S."7.70Purine metabolism abnormalities in a hyperuricosuric subclass of autism. ( Coleman, M; Page, T, 2000)
"A single male subject with hyperuricosuric autism was treated for a period of 2 years with an oral dose of uridine, which increased from 50 to 500 mg/kg/day."3.71Metabolic treatment of hyperuricosuric autism. ( Moseley, C; Page, T, 2002)
"A subclass of patients with classic infantile autism have uric acid excretion which is >2 S."3.70Purine metabolism abnormalities in a hyperuricosuric subclass of autism. ( Coleman, M; Page, T, 2000)
"The medical understanding of autism has changed since it was first defined by Kanner."2.46The review of most frequently occurring medical disorders related to aetiology of autism and the methods of treatment. ( Cubala-Kucharska, M, 2010)
"Metabolic consequences of HGPRT deficiency have been clarified, but the connection with the neurological manifestations is still unknown."1.31Cytosolic 5'-nucleotidase hyperactivity in erythrocytes of Lesch-Nyhan syndrome patients. ( Allegrini, S; Camici, M; Garcia-Gil, M; Jacomelli, G; Micheli, V; Peruzzi, L; Pesi, R; Tozzi, MG, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jurecka, A1
Tylki-Szymanska, A1
Zikanova, M1
Krijt, J1
Kmoch, S1
Cubala-Kucharska, M1
Page, T3
Coleman, M3
Pesi, R1
Micheli, V1
Jacomelli, G1
Peruzzi, L1
Camici, M1
Garcia-Gil, M1
Allegrini, S1
Tozzi, MG1
Moseley, C1
Nyhan, WL1
James, JA1
Teberg, AJ1
Sweetman, L1
Nelson, LG1

Reviews

1 review available for uric acid and Autism

ArticleYear
The review of most frequently occurring medical disorders related to aetiology of autism and the methods of treatment.
    Acta neurobiologiae experimentalis, 2010, Volume: 70, Issue:2

    Topics: Ammonia; Autistic Disorder; Child; Chronic Disease; Delivery of Health Care, Integrated; Gastrointes

2010

Other Studies

7 other studies available for uric acid and Autism

ArticleYear
D-ribose therapy in four Polish patients with adenylosuccinate lyase deficiency: absence of positive effect.
    Journal of inherited metabolic disease, 2008, Volume: 31 Suppl 2

    Topics: Adenosine; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Autistic Disorder; Blood Glucose; Chi

2008
De novo purine synthesis is increased in the fibroblasts of purine autism patients.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Autistic Disorder; Cells, Cultured; Fibroblasts; Gout; Humans; Lesch-Nyhan Syndrome; Purines; Refere

1998
Purine metabolism abnormalities in a hyperuricosuric subclass of autism.
    Biochimica et biophysica acta, 2000, Mar-17, Volume: 1500, Issue:3

    Topics: Autistic Disorder; Cells, Cultured; Child; Child, Preschool; Humans; Purines; Skin; Uric Acid

2000
Cytosolic 5'-nucleotidase hyperactivity in erythrocytes of Lesch-Nyhan syndrome patients.
    Neuroreport, 2000, Jun-26, Volume: 11, Issue:9

    Topics: 5'-Nucleotidase; Adolescent; Adult; Aminoimidazole Carboxamide; Animals; Apoptosis; Autistic Disorde

2000
Metabolic treatment of hyperuricosuric autism.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:2

    Topics: Administration, Oral; Adult; Autistic Disorder; Child; Humans; Male; Uric Acid; Uridine

2002
Studies of the autistic syndromes.
    Research publications - Association for Research in Nervous and Mental Disease, 1979, Volume: 57

    Topics: Adolescent; Autistic Disorder; Brain; Calcium; Catechol O-Methyltransferase; Cerebrovascular Circula

1979
A new disorder of purine metabolism with behavioral manifestations.
    The Journal of pediatrics, 1969, Volume: 74, Issue:1

    Topics: Adenine; Allopurinol; Autistic Disorder; Carbon Isotopes; Child Behavior Disorders; Child, Preschool

1969