urea and Polyarthritis studies

urea and Polyarthritis

urea has been researched along with Polyarthritis in 21 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

Excerpt	Relevance	Reference
" Dosing of rats with NCX-1015 (0."	1.31	Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis. ( Del Soldato, P; Flower, RJ; Mancini, L; Paul-Clark, MJ; Perretti, M, 2002)

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (66.67)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (19.05)	29.6817
2010's	2 (9.52)	24.3611
2020's	1 (4.76)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

14 (66.67)

18.7374

1990's

0 (0.00)

18.2507

2000's

4 (19.05)

29.6817

2010's

2 (9.52)

24.3611

2020's

1 (4.76)

2.80

Authors

Authors	Studies
Nawaz, S	1
Irfan, HM	1
Arshad, L	1
Jahan, S	1
Amir, M	1
Somakala, K	1
Ali, S	1
Yang, Z	1
Liang, Y	1
Li, C	1
Xi, W	1
Zhong, R	1
ARAPAKIS, G	1
TRIBE, CR	1
OYA, H	1
HIRAZAWA, T	1
HIRATA, F	1
TANIUCHI, A	1
ITO, N	1
JICK, H	1
KAMM, DE	1
SNYDER, JG	1
MORRISON, RS	1
CHALMERS, TC	1
BENDITT, EP	1
ERIKSEN, N	1
GERBER, DA	1
RUCKES, J	1
REISSLAND, G	1
Yellowlees, P	1
Greenfield, C	1
McIntyre, N	1
Redman, AM	2
Johnson, JS	1
Dally, R	1
Swartz, S	1
Wild, H	1
Paulsen, H	2
Caringal, Y	2
Gunn, D	2
Renick, J	1
Osterhout, M	2
Kingery-Wood, J	1
Smith, RA	2
Lee, W	2
Dumas, J	2
Wilhelm, SM	2
Housley, TJ	2
Bhargava, A	2
Ranges, GE	2
Shrikhande, A	2
Young, D	1
Bombara, M	1
Scott, WJ	2
Paul-Clark, MJ	1
Mancini, L	1
Del Soldato, P	1
Flower, RJ	1
Perretti, M	1
Kraus, VB	1
Huebner, JL	1
Fink, C	1
King, JB	1
Brown, S	1
Vail, TP	1
Guilak, F	1
Hatoum-Mokdad, H	1
Sibley, RN	1
Khire, U	1
Wood, J	1
Wolanin, D	1
Cooley, J	1
Bankston, D	1
Schoenleber, R	1
Romero, R	1
Pirro, J	1
Chien, DS	1
Muzsi, A	1
Bortolon, E	1
Wakefield, J	1
Gianpaolo Ostravage, C	1
Chau, T	1
Mohanaruban, K	1
Joglekar, M	1
Swift, CG	1
Tomlinson, K	1
Sipilä, R	1
Skrifvars, B	1
Törnroth, T	1
Maximescu, P	1
Oprişan, A	1
Pop, A	1
Potorac, E	1
Robinson, RG	1
Corrigan, AB	1
Konieczny, M	1
Teodorczyk, J	1
Bierowska, D	1
Szaga, B	1
Dorfmann, H	1
Kahn, MF	1
de Sèze, S	1
Crank, G	1
Foulis, MJ	1

Studies

Nawaz, S

Irfan, HM

Arshad, L

Jahan, S

Amir, M

Somakala, K

Ali, S

Yang, Z

Liang, Y

Li, C

Xi, W

Zhong, R

ARAPAKIS, G

TRIBE, CR

OYA, H

HIRAZAWA, T

HIRATA, F

TANIUCHI, A

ITO, N

JICK, H

KAMM, DE

SNYDER, JG

MORRISON, RS

CHALMERS, TC

BENDITT, EP

ERIKSEN, N

GERBER, DA

RUCKES, J

REISSLAND, G

Yellowlees, P

Greenfield, C

McIntyre, N

Redman, AM

Johnson, JS

Dally, R

Swartz, S

Wild, H

Paulsen, H

Caringal, Y

Gunn, D

Renick, J

Osterhout, M

Kingery-Wood, J

Smith, RA

Lee, W

Dumas, J

Wilhelm, SM

Housley, TJ

Bhargava, A

Ranges, GE

Shrikhande, A

Young, D

Bombara, M

Scott, WJ

Paul-Clark, MJ

Mancini, L

Del Soldato, P

Flower, RJ

Perretti, M

Kraus, VB

Huebner, JL

Fink, C

King, JB

Brown, S

Vail, TP

Guilak, F

Hatoum-Mokdad, H

Sibley, RN

Khire, U

Wood, J

Wolanin, D

Cooley, J

Bankston, D

Schoenleber, R

Romero, R

Pirro, J

Chien, DS

Muzsi, A

Bortolon, E

Wakefield, J

Gianpaolo Ostravage, C

Chau, T

Mohanaruban, K

Joglekar, M

Swift, CG

Tomlinson, K

Sipilä, R

Skrifvars, B

Törnroth, T

Maximescu, P

Oprişan, A

Pop, A

Potorac, E

Robinson, RG

Corrigan, AB

Konieczny, M

Teodorczyk, J

Bierowska, D

Szaga, B

Dorfmann, H

Kahn, MF

de Sèze, S

Crank, G

Foulis, MJ

Clinical Trials (1)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Mild, Moderate and Severe Osteoarthritis of the Knee[NCT03100799]		30 participants (Actual)	Interventional	2017-03-02	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Mild, Moderate and Severe Osteoarthritis of the Knee[NCT03100799]

30 participants (Actual)

Interventional

2017-03-02

Completed

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

21 other studies available for urea and Polyarthritis

Article	Year
Attenuation of CFA-induced chronic inflammation by a bicyclic monoterpene fenchone targeting inducible nitric oxide, prostaglandins, C-reactive protein and urea. Inflammopharmacology, 2023, Volume: 31, Issue:5 Topics: Animals; Arthritis; C-Reactive Protein; Camphanes; Cyclooxygenase 2; Freund's Adjuvant; Inflammation	2023
p38 MAP kinase inhibitors as anti inflammatory agents. Mini reviews in medicinal chemistry, 2013, Volume: 13, Issue:14 Topics: Amides; Animals; Anti-Inflammatory Agents; Arthritis; Binding Sites; Cyclooxygenase 2; Cytokines; Di	2013
Associations of serum urea, creatinine and uric acid with clinical and laboratory features in patients with systemic lupus erythematosus. Rheumatology international, 2012, Volume: 32, Issue:9 Topics: Arthritis; Biomarkers; China; Comorbidity; Creatinine; Exanthema; Female; Humans; Logistic Models; L	2012
AMYLOIDOSIS IN RHEUMATOID ARTHRITIS INVESTIGATED BY MEANS OF RECTAL BIOPSY. Annals of the rheumatic diseases, 1963, Volume: 22 Topics: Amyloidosis; Arthritis; Arthritis, Rheumatoid; Biopsy; Blood Chemical Analysis; Geriatrics; Humans;	1963
[CLINICAL CONTRIBUTION TO THE USE OF THE NEW ANALGESIC AND ANTIPYRETIC CALCIUM-ACETYL-SALICYLATE CARBAMIDE]. [Chiryo] [Therapy], 1963, Volume: 45 Topics: Analgesics; Antipyretics; Arthritis; Arthritis, Rheumatoid; Aspirin; Fibromyalgia; Humans; Neuritis;	1963
ON THE CONCENTRATING DEFECT IN CIRRHOSIS OF THE LIVER. The Journal of clinical investigation, 1964, Volume: 43 Topics: Alcoholism; Arthritis; Arthritis, Rheumatoid; Coronary Disease; Dehydration; Dermatitis; Diabetes Me	1964
AMYLOID. II. STARCH GEL ELECTROPHORETIC ANALYSIS OF SOME PROTEINS EXTRACTED FROM AMYLOID. Archives of pathology, 1964, Volume: 78 Topics: Adolescent; Amyloid; Amyloidosis; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Bronchiecta	1964
ROLE OF THE SULFHYDRYL GROUP IN THE DENATURATION OF HUMAN GAMMA-GLOBULIN. Journal of immunology (Baltimore, Md. : 1950), 1964, Volume: 92 Topics: Acetates; Arthritis; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; gamma-Globulins; Hot Temp	1964
[An experimental study on urea synthesis in the liver in inflammatory and traumatic injuries of the knee in rabbits. Comparative morphological study]. Zeitschrift fur die gesamte experimentelle Medizin, 1961, Volume: 135 Topics: Animals; Arthritis; Arthritis, Experimental; Disease; Knee; Knee Injuries; Knee Joint; Liver; Rabbit	1961
Dimethylsulphoxide-induced toxicity. Lancet (London, England), 1980, Nov-08, Volume: 2, Issue:8202 Topics: Acute Kidney Injury; Aged; Arthritis; Cerebral Infarction; Creatinine; Dimethyl Sulfoxide; Female; H	1980
p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas. Bioorganic & medicinal chemistry letters, 2001, Jan-08, Volume: 11, Issue:1 Topics: Arthritis; Enzyme Inhibitors; Furans; Humans; Inhibitory Concentration 50; Interleukin-6; Mitogen-Ac	2001
Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis. Proceedings of the National Academy of Sciences of the United States of America, 2002, Feb-05, Volume: 99, Issue:3 Topics: Alanine Transaminase; Animals; Arthritis; Aspartate Aminotransferases; Autoantibodies; Bone Resorpti	2002
Urea as a passive transport marker for arthritis biomarker studies. Arthritis and rheumatism, 2002, Volume: 46, Issue:2 Topics: Animals; Arthritis; Biological Transport; Biomarkers; Cartilage; Cartilage Oligomeric Matrix Protein	2002
Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor. Bioorganic & medicinal chemistry letters, 2002, Jun-17, Volume: 12, Issue:12 Topics: Administration, Oral; Animals; Arthritis; Cytokines; Enzyme Inhibitors; Mice; Mitogen-Activated Prot	2002
Significance of single serum urate estimations in acutely hospitalized elderly patients. Age and ageing, 1987, Volume: 16, Issue:4 Topics: Aged; Aged, 80 and over; Arthritis; Diuretics; Female; Gout; Humans; Male; Middle Aged; Predictive V	1987
Reversible non-oliguric impairment of renal function during azapropazone treatment. Scandinavian journal of rheumatology, 1986, Volume: 15, Issue:1 Topics: Acute Disease; Apazone; Arthritis; Creatinine; Female; Humans; Kidney Diseases; Male; Middle Aged; N	1986
Further studies on Corynebacterium species capable of producing diphtheria toxin (C. diphtheriae, C. ulcerans, C. ovis). Journal of general microbiology, 1974, Volume: 82, Issue:1 Topics: Animals; Arthritis; Bacteriophage Typing; Bacteriophages; Corynebacterium; Corynebacterium diphtheri	1974
Management of gout. Drugs, 1972, Volume: 3, Issue:5 Topics: Anti-Inflammatory Agents; Arthritis; Diet; Gout; Humans; Kidney Diseases; Phagocytes; Synovial Fluid	1972
Synthesis and pharmacological properties of cyclohexylureide-diallylmalonic acid and its derivatives. Archivum immunologiae et therapiae experimentalis, 1972, Volume: 20, Issue:6 Topics: Allyl Compounds; Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis; Chemical Phenomen	1972
[Possible iatrogenic lupus induced by phenturide (apropos of 2 cases)]. Annales de medecine interne, 1972, Volume: 123, Issue:4 Topics: Adolescent; Adult; Albuminuria; Arthritis; Endocarditis, Bacterial; Female; Humans; Iatrogenic Disea	1972
Derivatives of 2-aminooxazoles showing antiinflammatory activity. Journal of medicinal chemistry, 1971, Volume: 14, Issue:11 Topics: Administration, Oral; Amides; Animals; Anti-Inflammatory Agents; Arthritis; Central Nervous System;	1971

Article

Year

Attenuation of CFA-induced chronic inflammation by a bicyclic monoterpene fenchone targeting inducible nitric oxide, prostaglandins, C-reactive protein and urea.

Inflammopharmacology, 2023, Volume: 31, Issue:5

Topics: Animals; Arthritis; C-Reactive Protein; Camphanes; Cyclooxygenase 2; Freund's Adjuvant; Inflammation

2023

p38 MAP kinase inhibitors as anti inflammatory agents.

Mini reviews in medicinal chemistry, 2013, Volume: 13, Issue:14

Topics: Amides; Animals; Anti-Inflammatory Agents; Arthritis; Binding Sites; Cyclooxygenase 2; Cytokines; Di

2013

Associations of serum urea, creatinine and uric acid with clinical and laboratory features in patients with systemic lupus erythematosus.

Rheumatology international, 2012, Volume: 32, Issue:9

Topics: Arthritis; Biomarkers; China; Comorbidity; Creatinine; Exanthema; Female; Humans; Logistic Models; L

2012

AMYLOIDOSIS IN RHEUMATOID ARTHRITIS INVESTIGATED BY MEANS OF RECTAL BIOPSY.

Annals of the rheumatic diseases, 1963, Volume: 22

Topics: Amyloidosis; Arthritis; Arthritis, Rheumatoid; Biopsy; Blood Chemical Analysis; Geriatrics; Humans;

1963

[CLINICAL CONTRIBUTION TO THE USE OF THE NEW ANALGESIC AND ANTIPYRETIC CALCIUM-ACETYL-SALICYLATE CARBAMIDE].

[Chiryo] [Therapy], 1963, Volume: 45

Topics: Analgesics; Antipyretics; Arthritis; Arthritis, Rheumatoid; Aspirin; Fibromyalgia; Humans; Neuritis;

1963

ON THE CONCENTRATING DEFECT IN CIRRHOSIS OF THE LIVER.

The Journal of clinical investigation, 1964, Volume: 43

Topics: Alcoholism; Arthritis; Arthritis, Rheumatoid; Coronary Disease; Dehydration; Dermatitis; Diabetes Me

1964

AMYLOID. II. STARCH GEL ELECTROPHORETIC ANALYSIS OF SOME PROTEINS EXTRACTED FROM AMYLOID.

Archives of pathology, 1964, Volume: 78

Topics: Adolescent; Amyloid; Amyloidosis; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Bronchiecta

1964

ROLE OF THE SULFHYDRYL GROUP IN THE DENATURATION OF HUMAN GAMMA-GLOBULIN.

Journal of immunology (Baltimore, Md. : 1950), 1964, Volume: 92

Topics: Acetates; Arthritis; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; gamma-Globulins; Hot Temp

1964

[An experimental study on urea synthesis in the liver in inflammatory and traumatic injuries of the knee in rabbits. Comparative morphological study].

Zeitschrift fur die gesamte experimentelle Medizin, 1961, Volume: 135

Topics: Animals; Arthritis; Arthritis, Experimental; Disease; Knee; Knee Injuries; Knee Joint; Liver; Rabbit

1961

Dimethylsulphoxide-induced toxicity.

Lancet (London, England), 1980, Nov-08, Volume: 2, Issue:8202

Topics: Acute Kidney Injury; Aged; Arthritis; Cerebral Infarction; Creatinine; Dimethyl Sulfoxide; Female; H

1980

p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.

Bioorganic & medicinal chemistry letters, 2001, Jan-08, Volume: 11, Issue:1

Topics: Arthritis; Enzyme Inhibitors; Furans; Humans; Inhibitory Concentration 50; Interleukin-6; Mitogen-Ac

2001

Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis.

Proceedings of the National Academy of Sciences of the United States of America, 2002, Feb-05, Volume: 99, Issue:3

Topics: Alanine Transaminase; Animals; Arthritis; Aspartate Aminotransferases; Autoantibodies; Bone Resorpti

2002

Urea as a passive transport marker for arthritis biomarker studies.

Arthritis and rheumatism, 2002, Volume: 46, Issue:2

Topics: Animals; Arthritis; Biological Transport; Biomarkers; Cartilage; Cartilage Oligomeric Matrix Protein

2002

Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor.

Bioorganic & medicinal chemistry letters, 2002, Jun-17, Volume: 12, Issue:12

Topics: Administration, Oral; Animals; Arthritis; Cytokines; Enzyme Inhibitors; Mice; Mitogen-Activated Prot

2002

Significance of single serum urate estimations in acutely hospitalized elderly patients.

Age and ageing, 1987, Volume: 16, Issue:4

Topics: Aged; Aged, 80 and over; Arthritis; Diuretics; Female; Gout; Humans; Male; Middle Aged; Predictive V

1987

Reversible non-oliguric impairment of renal function during azapropazone treatment.

Scandinavian journal of rheumatology, 1986, Volume: 15, Issue:1

Topics: Acute Disease; Apazone; Arthritis; Creatinine; Female; Humans; Kidney Diseases; Male; Middle Aged; N

1986

Further studies on Corynebacterium species capable of producing diphtheria toxin (C. diphtheriae, C. ulcerans, C. ovis).

Journal of general microbiology, 1974, Volume: 82, Issue:1

Topics: Animals; Arthritis; Bacteriophage Typing; Bacteriophages; Corynebacterium; Corynebacterium diphtheri

1974

Management of gout.

Drugs, 1972, Volume: 3, Issue:5

Topics: Anti-Inflammatory Agents; Arthritis; Diet; Gout; Humans; Kidney Diseases; Phagocytes; Synovial Fluid

1972

Synthesis and pharmacological properties of cyclohexylureide-diallylmalonic acid and its derivatives.

Archivum immunologiae et therapiae experimentalis, 1972, Volume: 20, Issue:6

Topics: Allyl Compounds; Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis; Chemical Phenomen

1972

[Possible iatrogenic lupus induced by phenturide (apropos of 2 cases)].

Annales de medecine interne, 1972, Volume: 123, Issue:4

Topics: Adolescent; Adult; Albuminuria; Arthritis; Endocarditis, Bacterial; Female; Humans; Iatrogenic Disea

1972

Derivatives of 2-aminooxazoles showing antiinflammatory activity.

Journal of medicinal chemistry, 1971, Volume: 14, Issue:11

Topics: Administration, Oral; Amides; Animals; Anti-Inflammatory Agents; Arthritis; Central Nervous System;

1971