uracil has been researched along with Obesity in 10 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the study was to evaluate whether dipeptidyl peptidase-4 (DPP-4) inhibitor alogliptin (ALO) alone or in combination with pioglitazone (PIO) improves β-cell function along with insulin resistance (IR) in metformin (MET) treated obese women with PCOS with persistent IR." | 9.24 | Add on DPP-4 inhibitor alogliptin alone or in combination with pioglitazone improved β-cell function and insulin sensitivity in metformin treated PCOS. ( Goricar, K; Janez, A; Jensterle, M, 2017) |
| " The aim of the study was to evaluate whether dipeptidyl peptidase-4 (DPP-4) inhibitor alogliptin (ALO) alone or in combination with pioglitazone (PIO) improves β-cell function along with insulin resistance (IR) in metformin (MET) treated obese women with PCOS with persistent IR." | 5.24 | Add on DPP-4 inhibitor alogliptin alone or in combination with pioglitazone improved β-cell function and insulin sensitivity in metformin treated PCOS. ( Goricar, K; Janez, A; Jensterle, M, 2017) |
| "In a randomized controlled trial conducted at a single Dublin hospital between April 2002 and March 2004, we assessed the effect of folic acid supplementation on tissue folate, uracil misincorporation into DNA, and global DNA hypomethylation in colonocytes isolated from sites of adenomatous polyps and from histologically normal tissue adjacent and 10-15 cm distal to them." | 5.22 | Folic Acid Supplementation in Postpolypectomy Patients in a Randomized Controlled Trial Increases Tissue Folate Concentrations and Reduces Aberrant DNA Biomarkers in Colonic Tissues Adjacent to the Former Polyp Site. ( Downes, CS; McGlynn, AP; McKerr, G; McNulty, H; Molloy, AM; O'Reilly, SL; Reynolds, J; Scott, JM; Strain, JJ; Ward, M; Wasson, GR; Weir, DG, 2016) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Successful management of type 2 diabetes mellitus (T2DM) requires attention to additional conditions often associated with hyperglycemia including overweight or obesity, dyslipidemia and hypertension, as each has some relationship with microvascular or macrovascular complications." | 2.46 | Managing type 2 diabetes in the primary care setting: beyond glucocentricity. ( Kuritzky, L, 2010) |
| "In patients with type 2 diabetes mellitus (T2DM) inadequately controlled by metformin monotherapy, the addition of alogliptin contributed to clinically significant increases in pulmonary function through regulating glycemia and improving the imbalance of the oxidative-related substances in the serum, without increasing the incidence of hypoglycemia, dyslipidemia, dysarteriotony, and any notable increase in body weight." | 1.43 | The effect of alogliptin on pulmonary function in obese patients with type 2 diabetes inadequately controlled by metformin monotherapy. ( Dong, QY; Kuang, JS; Li, LB; Liu, XG; Tai, H; Wang, MY; Zhao, YP, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jensterle, M | 1 |
| Goricar, K | 1 |
| Janez, A | 1 |
| Whon, TW | 1 |
| Shin, NR | 1 |
| Jung, MJ | 1 |
| Hyun, DW | 1 |
| Kim, HS | 1 |
| Kim, PS | 1 |
| Bae, JW | 1 |
| Zhu, B | 1 |
| Li, Y | 1 |
| Mei, W | 1 |
| He, M | 1 |
| Ding, Y | 1 |
| Meng, B | 1 |
| Zhao, H | 1 |
| Xiang, G | 1 |
| Hussar, DA | 1 |
| O'Reilly, SL | 1 |
| McGlynn, AP | 1 |
| McNulty, H | 1 |
| Reynolds, J | 1 |
| Wasson, GR | 1 |
| Molloy, AM | 1 |
| Strain, JJ | 1 |
| Weir, DG | 1 |
| Ward, M | 1 |
| McKerr, G | 1 |
| Scott, JM | 1 |
| Downes, CS | 1 |
| Tai, H | 1 |
| Wang, MY | 1 |
| Zhao, YP | 1 |
| Li, LB | 1 |
| Dong, QY | 1 |
| Liu, XG | 1 |
| Kuang, JS | 1 |
| Hedge, AM | 1 |
| Sharma, A | 1 |
| Kuritzky, L | 1 |
| Rieg, T | 1 |
| Gerasimova, M | 1 |
| Murray, F | 1 |
| Masuda, T | 1 |
| Tang, T | 1 |
| Rose, M | 1 |
| Drucker, DJ | 1 |
| Vallon, V | 1 |
2 reviews available for uracil and Obesity
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Managing type 2 diabetes in the primary care setting: beyond glucocentricity.
Topics: Adamantane; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors | 2010 |
3 trials available for uracil and Obesity
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Add on DPP-4 inhibitor alogliptin alone or in combination with pioglitazone improved β-cell function and insulin sensitivity in metformin treated PCOS.
Topics: Adult; Body Mass Index; Cohort Studies; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitor | 2017 |
Folic Acid Supplementation in Postpolypectomy Patients in a Randomized Controlled Trial Increases Tissue Folate Concentrations and Reduces Aberrant DNA Biomarkers in Colonic Tissues Adjacent to the Former Polyp Site.
Topics: Adenomatous Polyps; Aged; Biomarkers; Body Mass Index; Colon; Colonic Neoplasms; Colonoscopy; Comet | 2016 |
6 other studies available for uracil and Obesity
| Article | Year |
|---|---|
Conditionally Pathogenic Gut Microbes Promote Larval Growth by Increasing Redox-Dependent Fat Storage in High-Sugar Diet-Fed Drosophila.
Topics: Animals; Bacteria; Disease Models, Animal; Drosophila melanogaster; Gastrointestinal Tract; Germ-Fre | 2017 |
Alogliptin improves endothelial function by promoting autophagy in perivascular adipose tissue of obese mice through a GLP-1-dependent mechanism.
Topics: Adipokines; Adipose Tissue; Animals; Aorta, Thoracic; Autophagy; Dipeptidyl-Peptidase IV Inhibitors; | 2019 |
New drugs 2014, part 1.
Topics: Abatacept; Adult; Anticoagulants; Antidiarrheals; Antitubercular Agents; Benzazepines; Canagliflozin | 2014 |
The effect of alogliptin on pulmonary function in obese patients with type 2 diabetes inadequately controlled by metformin monotherapy.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agen | 2016 |
Genetic sensitivity to 6-n-propylthiouracil (PROP) as a screening tool for obesity and dental caries in children.
Topics: Analysis of Variance; Body Mass Index; Chi-Square Distribution; Child; Dental Caries; Dental Caries | 2008 |
Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Gl | 2012 |