uracil and Fatigue
uracil has been researched along with Fatigue in 10 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sorafenib, a multi-kinase inhibitor with anti-angiogenic activity, was recently approved for the treatment of advanced hepatocellular carcinoma (HCC)." | 9.14 | Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma. ( Chen, PJ; Cheng, AL; Ding, YH; Hsu, C; Hsu, CH; Lin, ZZ; Shao, YY; Shen, YC, 2010) |
| "Standard chemotherapy for advanced biliary tract cancer has not been established." | 6.72 | Early phase II study of uracil-tegafur plus doxorubicin in patients with unresectable advanced biliary tract cancer. ( Funakoshi, A; Furuse, J; Horikawa, Y; Ikeda, M; Ishii, H; Mizuno, N; Morizane, C; Nagase, M; Nakachi, K; Okusaka, T; Ueno, H; Yamao, K, 2006) |
| "Sorafenib, a multi-kinase inhibitor with anti-angiogenic activity, was recently approved for the treatment of advanced hepatocellular carcinoma (HCC)." | 5.14 | Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma. ( Chen, PJ; Cheng, AL; Ding, YH; Hsu, C; Hsu, CH; Lin, ZZ; Shao, YY; Shen, YC, 2010) |
| " However, information about the rate of adverse events (AEs) across different DAA regimens is limited." | 2.87 | Outcome and adverse events in patients with chronic hepatitis C treated with direct-acting antivirals: a clinical randomized study. ( Andersen, ES; Bukh, J; Christensen, PB; Fahnøe, U; Gerstoft, J; Kjær, MS; Laursen, AL; Mössner, B; Pedersen, MS; Røge, BT; Schønning, K; Sølund, C; Weis, N, 2018) |
| "Standard chemotherapy for advanced biliary tract cancer has not been established." | 2.72 | Early phase II study of uracil-tegafur plus doxorubicin in patients with unresectable advanced biliary tract cancer. ( Funakoshi, A; Furuse, J; Horikawa, Y; Ikeda, M; Ishii, H; Mizuno, N; Morizane, C; Nagase, M; Nakachi, K; Okusaka, T; Ueno, H; Yamao, K, 2006) |
| " Intolerance to single dosing was clearly demonstrated, and only the split dosing was advanced to 500 mg/m2/day." | 2.68 | Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil. ( Chan, KK; Groshen, S; Jeffers, S; Leichman, CG; Leichman, L; Muggia, FM; Spicer, D; Wu, X, 1996) |
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Sølund, C | 1 |
| Andersen, ES | 1 |
| Mössner, B | 1 |
| Laursen, AL | 1 |
| Røge, BT | 1 |
| Kjær, MS | 1 |
| Gerstoft, J | 1 |
| Christensen, PB | 1 |
| Pedersen, MS | 1 |
| Schønning, K | 1 |
| Fahnøe, U | 1 |
| Bukh, J | 1 |
| Weis, N | 1 |
| Bendell, JC | 1 |
| Rosen, LS | 1 |
| Mayer, RJ | 1 |
| Goldman, JW | 1 |
| Infante, JR | 1 |
| Benedetti, F | 1 |
| Lin, D | 1 |
| Mizuguchi, H | 1 |
| Zergebel, C | 1 |
| Patel, MR | 1 |
| Hsu, CH | 1 |
| Shen, YC | 1 |
| Lin, ZZ | 1 |
| Chen, PJ | 1 |
| Shao, YY | 1 |
| Ding, YH | 1 |
| Hsu, C | 1 |
| Cheng, AL | 1 |
| BAKLI, NM | 1 |
| MEERSON, FZ | 1 |
| POGOSIAN, LA | 1 |
| SHENDEROV, SM | 1 |
| Furuse, J | 1 |
| Okusaka, T | 1 |
| Funakoshi, A | 1 |
| Yamao, K | 1 |
| Nagase, M | 1 |
| Ishii, H | 1 |
| Nakachi, K | 1 |
| Ueno, H | 1 |
| Ikeda, M | 1 |
| Morizane, C | 1 |
| Horikawa, Y | 1 |
| Mizuno, N | 1 |
| Muggia, FM | 1 |
| Wu, X | 1 |
| Spicer, D | 1 |
| Groshen, S | 1 |
| Jeffers, S | 1 |
| Leichman, CG | 1 |
| Leichman, L | 1 |
| Chan, KK | 1 |
| Bokemeyer, C | 1 |
| Hartmann, JT | 1 |
| Mayer, F | 1 |
| Böhlke, I | 1 |
| Kanz, L | 1 |
| Von Pawel, J | 1 |
| Derigs, G | 1 |
| Schröder, M | 1 |
| Colevas, AD | 1 |
| Amrein, PC | 1 |
| Gomolin, H | 1 |
| Barton, JJ | 1 |
| Read, RR | 1 |
| Adak, S | 1 |
| Benner, S | 1 |
| Costello, R | 1 |
| Posner, MR | 1 |
| Chauchard, P | 1 |
| Iakovlev, NN | 1 |
Reviews
1 review available for uracil and Fatigue
| Article | Year |
|---|---|
[Physiological aspects of endurance during muscular activity].
Topics: Adenosine Triphosphate; Amphetamine; Brain; Fatigue; Humans; Mitochondria, Muscle; Muscles; Myocardi | 1970 |
Trials
7 trials available for uracil and Fatigue
| Article | Year |
|---|---|
Outcome and adverse events in patients with chronic hepatitis C treated with direct-acting antivirals: a clinical randomized study.
Topics: 2-Naphthylamine; Adult; Anemia; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropane | 2018 |
Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplasti | 2015 |
Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Benzenesul | 2010 |
Early phase II study of uracil-tegafur plus doxorubicin in patients with unresectable advanced biliary tract cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; | 2006 |
Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Cohor | 1996 |
UFT/leucovorin plus weekly paclitaxel in the treatment of solid tumors.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Dose-Re | 2000 |
A phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anemia; Antimetabolites, Antineoplastic; Antin | 2001 |
Other Studies
2 other studies available for uracil and Fatigue
| Article | Year |
|---|---|
[THE EFFECT OF NUCLEOSIDES, STROPHANTHIN AND COMBINATIONS OF THESE FACTORS ON THE DEVELOPMENT OF THE PROCESS OF FATIGUE IN THE MYOCARDIUM].
Topics: Animals; Dermatologic Agents; Expectorants; Fatigue; Hypoxanthines; Lagomorpha; Myocardium; Nucleosi | 1964 |
[Effect of various purine and pyrimidine bases on the metachronosis of vibration].
Topics: Adenosine Triphosphate; Animals; Cytidine; Cytosine; Fatigue; Guanine; Nucleic Acids; Purines; Pyrim | 1969 |