triazoles has been researched along with Sarcoma in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abdul Razak, A; Accardi, S; Al-Ezzi, E; Fasih, S; Gupta, A; Lewin, J; Malone, E; Pedersen, P | 1 |
| Musi, E; Nair, JS; Schwartz, GK | 1 |
| Ji, L; Li, S; Liu, S; Liu, Z; Meng, X; Tang, S; Yang, S; Yu, S | 1 |
| Alam, MZ; Chor, S; Ciotti, GE; Egolf, S; Eisinger-Mathason, TSK; Grazioli, A; Haldar, M; Lawlor, MA; Lee, AC; Marino, GE; Niedzwicki, D; Pak, K; Park, PMC; Perry, JA; Qi, J; Rivera-Reyes, A; Shah, J; Weber, K; Xu, M; Ye, S | 1 |
| Chen, AP; Do, K; Doroshow, JH; Juwara, L; Kummar, S; Meehan, R; O'Sullivan Coyne, G; Rubinstein, L; Zlott, J | 1 |
| Babichev, Y; C Brady, D; Chor, S; E Ciotti, G; E Marino, G; Egolf, S; Eisinger-Mathason, TSK; Gladdy, R; Koumenis, C; Leli, NM; Liu, Y; Mancuso, A; Pak, K; Park, PMC; Posimo, JM; Qi, J; Rivera-Reyes, A; Sostre-Colón, J; Tameire, F; Weber, K; Ye, S | 1 |
| Baker, LH; Bid, HK; Guttridge, DC; Houghton, PJ; Lin, J; London, C; Mo, X; Phelps, DA; Xaio, L | 1 |
| Anatone, AJ; Czaplinski, JT; Demetri, GD; Fletcher, JA; Nakayama, R; Sicinska, ET; Wagner, AJ; Zhang, YX | 1 |
| Bielski, CM; Boehm, JS; Cheah, JH; Church, AJ; Cima, MJ; Clemons, PA; Cowley, GS; Crompton, BD; Doshi, MB; Garraway, LA; Gill, S; Hahn, WC; Hong, AL; Howell, S; Imamovic, A; Janeway, KA; Jonas, O; Keskula, P; Kryukov, GV; Kynnap, BD; Langer, RS; Meyer, SC; Oh, C; Roberts, CW; Rodriguez-Galindo, C; Root, DE; Schreiber, SL; Shamji, AF; Stegmaier, K; Tseng, YY; Tsherniak, A; van Hummelen, P; Vazquez, F | 1 |
| Abdul Razak, AR; Baker, S; Carlson, R; Condy, M; D'Angelo, SP; Dickson, MA; Ellis, J; Erinjeri, JP; Friedlander, S; Gounder, MM; Gupta, AA; Jasmine, FH; Kauffman, M; Keohan, ML; Loong, HH; Nyquist-Schultz, K; Rashal, T; Saint-Martin, JR; Salah, S; Schwartz, GK; Shacham, S; Tanner, L; Tap, WD; Unger, TJ; Zer, A | 1 |
| Fang, RY; He, QJ; Lou, YJ; Yang, B; Zhu, DY | 1 |
| Benshahar, D; Capellaere, P; Kerbrat, P; Rouëssé, JG; Thomas, D; van Coninge, CJ; van Oosterom, AT | 1 |
3 trial(s) available for triazoles and Sarcoma
| Article | Year |
|---|---|
A phase 1b trial of selinexor, a first-in-class selective inhibitor of nuclear export (SINE), in combination with doxorubicin in patients with advanced soft tissue sarcomas (STS).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Follow-Up Studies; Humans; Hydrazines; Male; Maximum Tolerated Dose; Middle Aged; Non-Randomized Controlled Trials as Topic; Prognosis; Sarcoma; Tissue Distribution; Triazoles | 2021 |
A Phase I Study of Ganetespib and Ziv-Aflibercept in Patients with Advanced Carcinomas and Sarcomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Neoplasms; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Sarcoma; Triazoles | 2018 |
Phase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma.
Topics: Active Transport, Cell Nucleus; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biopsy; Canada; Capsules; Disease Progression; Drug Administration Schedule; Drug Compounding; Fasting; Female; Food-Drug Interactions; Humans; Hydrazines; Male; Middle Aged; New York City; Pharmaceutical Solutions; Postprandial Period; Sarcoma; Soft Tissue Neoplasms; Tablets; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Triazoles; Young Adult | 2016 |
9 other study(ies) available for triazoles and Sarcoma
| Article | Year |
|---|---|
Selinexor (KPT-330) Induces Tumor Suppression through Nuclear Sequestration of IκB and Downregulation of Survivin.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Survival; Exportin 1 Protein; Humans; Hydrazines; I-kappa B Proteins; Inhibitor of Apoptosis Proteins; Karyopherins; Mice; NF-kappa B; Oligopeptides; Receptors, Cytoplasmic and Nuclear; Sarcoma; Survivin; Transcription Factor RelA; Triazoles; Xenograft Model Antitumor Assays | 2017 |
A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Colonic Neoplasms; DNA; DNA Replication; DNA Topoisomerases, Type II; HCT116 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthalimides; Sarcoma; Triazoles; Xenograft Model Antitumor Assays | 2017 |
YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis.
Topics: Adaptor Proteins, Signal Transducing; Angiomotins; Animals; Antineoplastic Agents; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hippo Signaling Pathway; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Microfilament Proteins; Muscle, Skeletal; NF-kappa B; Phosphoproteins; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Sarcoma; Signal Transduction; Soft Tissue Neoplasms; Transcription Factors; Triazoles; Ubiquitin-Specific Proteases; Vorinostat; YAP-Signaling Proteins | 2018 |
YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma.
Topics: Activating Transcription Factor 6; Adaptor Proteins, Signal Transducing; Animals; Autophagy; Azepines; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Circadian Clocks; CLOCK Proteins; eIF-2 Kinase; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; Muscle Neoplasms; Muscle, Skeletal; Myoblasts; NF-kappa B; Sarcoma; Signal Transduction; Stem Cells; Triazoles; Unfolded Protein Response; Vorinostat; YAP-Signaling Proteins | 2018 |
The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Azepines; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Child; Disease Models, Animal; Drug Resistance, Neoplasm; Human Umbilical Vein Endothelial Cells; Humans; Mice; Neovascularization, Pathologic; Proto-Oncogene Proteins c-myc; Sarcoma; Transcription Factor AP-1; Triazoles; Xenograft Model Antitumor Assays | 2016 |
Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma.
Topics: Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Exportin 1 Protein; Female; G1 Phase Cell Cycle Checkpoints; Humans; Hydrazines; Karyopherins; Mice, Nude; Proto-Oncogene Proteins c-kit; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma; Signal Transduction; Triazoles; Xenograft Model Antitumor Assays | 2016 |
Integrated genetic and pharmacologic interrogation of rare cancers.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; CRISPR-Cas Systems; Cyclin-Dependent Kinase 4; Doxorubicin; Drug Screening Assays, Antitumor; Exome; Exportin 1 Protein; Female; Genomics; Humans; Hydrazines; Karyopherins; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Transplantation; Piperazines; Pyridines; Rare Diseases; Receptors, Cytoplasmic and Nuclear; RNA Interference; Sarcoma; Sequence Analysis, RNA; Triazoles | 2016 |
Antiproliferative activity of contragestazol (DL111-IT) in murine and human tumor models in vitro and in vivo.
Topics: Animals; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Female; Flow Cytometry; Gene Expression Profiling; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Sarcoma; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured | 2006 |
Phase II study of 1,2,4-triglycidyl urasol (TGU) in advanced soft tissue sarcoma. A trial of the EORTC Soft Tissue and Bone Sarcoma Cooperative Group.
Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leukopenia; Male; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Thrombocytopenia; Triazoles | 1987 |