triazoles has been researched along with Hypoxia in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (4.41) | 18.7374 |
| 1990's | 17 (25.00) | 18.2507 |
| 2000's | 21 (30.88) | 29.6817 |
| 2010's | 23 (33.82) | 24.3611 |
| 2020's | 4 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Anekal, PV; Bogle, G; Buckley, CD; Dickson, BD; Hay, MP; Hicks, KO; Hong, CR; Wilson, WR; Wong, WW | 1 |
| Gom, RC; Phillips, TJ; Teskey, GC; Wolff, MD | 1 |
| Fukui, K; Hasegawa, S; Nangaku, M; Saito, T; Susaki, EA; Tanaka, T; Ueda, HR; Wakashima, T | 1 |
| Ang, BT; Cheng, HS; Chong, YK; Law, CLD; Low, ZYJ; Marvalim, C; Tan, NS; Tang, C; Zhu, P | 1 |
| Jensen, BL | 1 |
| Abdulmalik, O; Berra, L; Bloch, DB; Chen, Q; Cooper, MK; Ferrari, M; Klings, ES; Liu, C; Musayev, FN; Nakagawa, A; Safo, MK; Safo, RS; Schleifer, G; Yu, B; Zapol, WM | 1 |
| Du, K; Feng, F; Li, X; Sun, J | 1 |
| Abdul-Salam, VB; Chien-Nien, C; Dubois, O; Endruschat, J; Gierula, M; Mahomed, AS; Russomanno, G; Schaeper, U; Wilkins, MR; Wojciak-Stothard, B; Yates, LA; Zhao, L | 1 |
| Audran, M; Domergue, V; Marchand, A; Roulland, I; Schröder, K; Semence, F | 1 |
| Aibe, N; Kagiya, T; Nakamura, S; Nishimura, T; Okabe, H; Yamazaki, H; Yoshida, K | 1 |
| Dastych, J; Mazerska, Z; Niemira, M | 1 |
| Gu, Y; Han, Y; Ma, G; Shi, H; Tang, C; Wang, Q; Yan, G | 1 |
| Frøbert, O; Hedegaard, ER; Mogensen, S; Nielsen, BD; Rembold, CM; Simonsen, U | 1 |
| D'Arcy, P; Dang, L; De Milito, A; Fayad, W; Fryknäs, M; Gogvadze, V; Gullbo, J; Hernlund, E; Larsson, R; Linder, S; Nygren, P; Olofsson, MH; Påhlman, S; Rickardson, L; Schughart, LA; Zhang, X | 1 |
| Duggan, N; Fullerton, J; Hussey, MJ; Loughlin, L; MacLean, MR; Mair, KM; Nilsen, M; Roberts, S; Rowlands, DJ; Thomas, M; Wright, AF | 1 |
| Abid, S; Adnot, S; Amsellem, V; Bobe, R; Combadière, C; Delcroix, M; Dubois-Randé, JL; Gary-Bobo, G; Gladwin, MT; Houssaini, A; Lipskaia, L; Marcos, E; Mouraret, N; Norris, KA; Parpaleix, A; Poupel, L; Quarck, R; Saker, M | 1 |
| Abdulmalik, O; Bloch, KD; Casalena, D; Lui, FE; Meadows, J; Mozzarelli, A; Nakagawa, A; Palmer, MA; Ronda, L; Safo, MK; Wassaf, D; Yefidoff-Freedman, R; Zapol, WM | 1 |
| De Ruysscher, D; Eriksson, J; Even, AJ; Hoebers, FJ; Houben, RM; Lambin, P; Mottaghy, FM; Ollers, MC; Reymen, B; Troost, EG; van Elmpt, W; Windhorst, AD; Zegers, CM | 1 |
| Betts, HM; Dutton, D; Perkins, AC; Turton, DR | 1 |
| Bennink, RJ; Besselink, MG; Bijlsma, MF; Hulshof, MC; Klaassen, R; Nederveen, AJ; van Berge Henegouwen, MI; van Laarhoven, HW; van Tienhoven, G; Wilmink, JW; Windhorst, AD | 1 |
| Mönnich, D; Thorwarth, D; Troost, EG; van Elmpt, W; Wack, LJ; Zegers, CM; Zips, D | 1 |
| Hoebers, FJ; Lambin, P; Mottaghy, FM; Öllers, MC; Troost, EG; van Elmpt, W; Zegers, CM | 1 |
| Chu, T; Huang, H; Zhang, Q | 1 |
| Baban, D; Bridges, E; da Motta, LL; De Bastiani, MA; Ebner, D; Haider, S; Harris, AL; Klamt, F; Knapp, S; Ledaki, I; Li, JL; McIntyre, A; Morotti, M; Purshouse, K; Steers, G; Wigfield, S | 1 |
| da Silva, Fde C; de Souza, IC; Faro, LV; Ferreira, VF; Gonzaga, DT; Lanznaster, M; Miranda, Fda S; Pinheiro, CB; Scarpellini, M | 1 |
| Bairam, A; Kinkead, R; Montandon, G | 1 |
| De Meester, I; Lambeir, AM; Scharpé, S | 1 |
| Hamilton, JB; Lancaster, DM; Patel, N; Pietersen, AN; Vreugdenhil, M | 1 |
| Aloisi, AM; Ceccarelli, I; Fiorenzani, P; Pessina, F; Sgaragli, G; Valeri, A | 1 |
| Koos, BJ; Maeda, T | 1 |
| Alpaugh, K; Bélanger, MJ; Doss, M; Hostetler, ED; Kolb, HC; Stubbs, JB; Yu, JQ; Zhang, JJ | 1 |
| Carlin, S; Humm, JL | 1 |
| Feldkamp, T; Heemann, U; Herget-Rosenthal, S; Horbelt, M; Kribben, A; Lange, B; Philipp, T; Pietruck, F | 1 |
| Henrich, M; Kummer, W; Snipes, RL; Yamamoto, Y | 1 |
| Casillan, AJ; Gonzalez, NC; Johnson, JS; Steiner, DR; Wood, JG | 1 |
| Corradetti, R; Latini, S; Pedata, F; Pugliese, AM | 1 |
| Brodmann, M; Lischnig, U; Lueger, A; Pilger, E; Stark, G | 1 |
| Addae, JI; Stone, TW; Youssef, FF | 1 |
| Al-Salti, W; Booth, IW; Coney, AM; Ewer, AK; Marshall, JM; Ramani, P | 1 |
| Banerjee, S; Chakraborty, S; Das, T; Kagiya, VT; Mukherjee, A; Nair, CK; Samuel, G; Sarma, HD; Venkatesh, M | 1 |
| Colgan, SP; Eltzschig, HK; Ibla, JC; Morote-Garcia, JC; Resta, R; Thompson, LF; Van De Wiele, CJ | 1 |
| Bohorquez, F; Kawasaki, Y; Kim, YH; Koos, BJ | 1 |
| Deussen, A; Frøbert, O; Gravholt, CH; Haink, G; Levin, M; Simonsen, U | 1 |
| Coppi, E; Corradetti, R; Pedata, F; Pugliese, AM; Spalluto, G | 1 |
| Conde, SV; Gonzalez, C; Obeso, A; Rigual, R; Rocher, A; Vicario, I | 1 |
| Baranyi, M; Illes, P; Sperlágh, B; Vizi, ES; Zsilla, G | 1 |
| Abdallah, MF; Ibe, BO; Portugal, AM; Raj, JU | 1 |
| Howell, LL; Landrum, AM | 1 |
| Arnould, T; Delaive, E; Janssens, D; Michiels, C; Remacle, J | 1 |
| Hatton, CJ; Peers, C | 2 |
| Coney, AM; Marshall, JM | 1 |
| Bryan, PT; Marshall, JM | 1 |
| Ghofrani, HA; Grimminger, F; Hardebusch, T; Rosseau, S; Schermuly, R; Seeger, W; Voswinckel, R; Weissmann, N | 1 |
| Edmunds, NJ; Marshall, JM | 1 |
| Ferrarini, PL; Livi, O | 1 |
| Ono, S; Voelkel, NF; Westcott, JY | 1 |
| Chang, SW; Dutton, D; Giacomini, KM; He, LS; Hui, A; Ortiz de Montellano, P; Stearns, R; Voelkel, NF; Wang, HL | 1 |
| Chang, SW; Chen, CR; Voelkel, NF | 1 |
| Brandt, R; Kanowski, U; Kempfert, C; Oddoy, A; Siewert, B | 1 |
| Caplan, MS; Hsueh, W; Sun, XM | 2 |
| Bradley, LM; Czaja, JF; Goldstein, RE; Stambouly, JJ | 1 |
| Chang, S; Czartalomna, J; Feddersen, CO; Voelkel, NF | 1 |
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Barnes, PJ; Evans, TW; McCormack, DG | 2 |
| Thorling, EB | 1 |
3 review(s) available for triazoles and Hypoxia
| Article | Year |
|---|---|
DPP4 inhibitors for diabetes--what next?
Topics: Adamantane; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Hypoxia; Neoplasms; Nitriles; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin | 2008 |
PET of hypoxia: current and future perspectives.
Topics: Etanidazole; Humans; Hydrocarbons, Fluorinated; Hypoxia; Nitroimidazoles; Positron-Emission Tomography; Radioactive Tracers; Triazoles | 2012 |
Hypoxia, PAF, and necrotizing enterocolitis.
Topics: Animals; Azepines; Enterocolitis; Humans; Hypoxia; Intestines; Necrosis; Platelet Activating Factor; Quinolinium Compounds; Triazoles | 1991 |
1 trial(s) available for triazoles and Hypoxia
| Article | Year |
|---|---|
Biodistribution and radiation dosimetry of the hypoxia marker 18F-HX4 in monkeys and humans determined by using whole-body PET/CT.
Topics: Animals; Biomarkers; Female; Haplorhini; Humans; Hypoxia; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Radiometry; Radiopharmaceuticals; Species Specificity; Tomography, X-Ray Computed; Triazoles; Whole Body Imaging | 2010 |
64 other study(ies) available for triazoles and Hypoxia
| Article | Year |
|---|---|
Radiosensitisation of SCCVII tumours and normal tissues in mice by the DNA-dependent protein kinase inhibitor AZD7648.
Topics: Animals; DNA; DNA-Activated Protein Kinase; Head and Neck Neoplasms; Humans; Hypoxia; Mice; Mice, Inbred C3H; Purines; Pyrans; Squamous Cell Carcinoma of Head and Neck; Triazoles | 2022 |
Caffeine Exacerbates Postictal Hypoxia.
Topics: Adenosine; Animals; CA1 Region, Hippocampal; Caffeine; Dose-Response Relationship, Drug; Hypoxia; Kindling, Neurologic; Male; Oxygen; Phenethylamines; Pyrimidines; Rats; Receptors, Adenosine A2; Seizures; Triazoles | 2019 |
The oral hypoxia-inducible factor prolyl hydroxylase inhibitor enarodustat counteracts alterations in renal energy metabolism in the early stages of diabetic kidney disease.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Energy Metabolism; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Mice; N-substituted Glycines; Prolyl-Hydroxylase Inhibitors; Pyridines; Rats; Triazoles | 2020 |
Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.
Topics: Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Hypoxia; Male; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-met; Pyrazines; Pyrrolidinones; Quinolines; Signal Transduction; Temozolomide; Transcriptome; Triazoles | 2021 |
Get use to the -dustats: Roxadustat and molidustat, members of the hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor drug class promote kidney function, perfusion and oxygenation in rats through nitric oxide.
Topics: Animals; Glycine; Hypoxia; Isoquinolines; Kidney; Nitric Oxide; Perfusion; Pharmaceutical Preparations; Prolyl Hydroxylases; Prolyl-Hydroxylase Inhibitors; Pyrazoles; Rats; Triazoles | 2021 |
A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells.
Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Disulfides; Erythrocytes; Hemoglobin, Sickle; Hemoglobins; Humans; Hypoxia; Metallothionein 3; Mice; Mice, Inbred C57BL; Oxygen; Polymerization; Protein Binding; Triazoles | 2018 |
A water soluble donor-acceptor-donor conjugated oligomer as a photosensitizer for mitochondria-targeted photodynamic therapy.
Topics: Antineoplastic Agents; Fluorescent Dyes; HeLa Cells; Humans; Hypoxia; Mitochondria; Organophosphorus Compounds; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen; Triazoles | 2018 |
CLIC4/Arf6 Pathway.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Antihypertensive Agents; Bone Morphogenetic Protein Receptors, Type II; Cells, Cultured; Chloride Channels; Disease Models, Animal; Endothelial Cells; Humans; Hypertension, Pulmonary; Hypoxia; Inflammation Mediators; Mice, Inbred C57BL; Mitochondrial Proteins; Molecular Targeted Therapy; Monocrotaline; Proteomics; Pulmonary Artery; Rats; RNA, Small Interfering; RNAi Therapeutics; Signal Transduction; Triazoles | 2019 |
Detection of Hypoxia-Regulated MicroRNAs in Blood as Potential Biomarkers of HIF Stabilizer Molidustat.
Topics: Animals; Biomarkers; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; MicroRNAs; Protein Stability; Pyrazoles; Rats; Rats, Wistar; Triazoles | 2019 |
Intensity-modulated radiation therapy with hypoxic sensitizer AK-2123 (sanazole) for glioblastoma multiforme using simultaneous integrated boost technique.
Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans; Hypoxia; Middle Aged; Prognosis; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Triazoles | 2013 |
Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia.
Topics: Acridines; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Western; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; DNA Primers; Hep G2 Cells; Humans; Hypoxia; Nitracrine; Pregnane X Receptor; Real-Time Polymerase Chain Reaction; Receptors, Steroid; Triazoles; Up-Regulation | 2013 |
Regulation of rat intrapulmonary arterial tone by arachidonic acid and prostaglandin E2 during hypoxia.
Topics: Animals; Arachidonic Acid; Calcium; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Hypoxia; Male; Muscle Tonus; Oxytocics; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Prostaglandin E; Thiophenes; Triazoles; Vasoconstriction; Xanthones | 2013 |
Mechanisms involved in increased sensitivity to adenosine A(2A) receptor activation and hypoxia-induced vasodilatation in porcine coronary arteries.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Cyclic AMP; Dinoprost; HSP20 Heat-Shock Proteins; Hypoxia; In Vitro Techniques; Oxygen; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilation | 2014 |
Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.
Topics: Animals; Antineoplastic Agents; Autophagy; Drug Screening Assays, Antitumor; Female; Glucose; Glycolysis; HCT116 Cells; HT29 Cells; Humans; Hydrazones; Hypoxia; Mice; Mitochondria; Oxidative Phosphorylation; Spheroids, Cellular; Triazoles; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2014 |
Sex-dependent influence of endogenous estrogen in pulmonary hypertension.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Estrogens; Female; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Mice, Inbred C57BL; Nitriles; Polymerase Chain Reaction; Rats; Rats, Wistar; Sex Factors; Triazoles | 2014 |
CCR5 as a treatment target in pulmonary arterial hypertension.
Topics: Animals; CCR5 Receptor Antagonists; Cell Proliferation; Cells, Cultured; Cyclohexanes; Disease Models, Animal; Familial Primary Pulmonary Hypertension; HIV Fusion Inhibitors; HIV Infections; Humans; Hypertension, Pulmonary; Hypoxia; Macaca mulatta; Macrophages; Male; Maraviroc; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Pulmonary Artery; Receptors, CCR5; Simian Acquired Immunodeficiency Syndrome; Triazoles | 2014 |
Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling.
Topics: Anemia, Sickle Cell; Crystallography, X-Ray; Disulfides; Erythrocytes; Hemoglobin, Sickle; Hemoglobins; Hemolysis; High-Throughput Screening Assays; Humans; Hypoxia; Molecular Structure; Oxygen; Protein Conformation; Small Molecule Libraries; Triazoles | 2014 |
In vivo quantification of hypoxic and metabolic status of NSCLC tumors using [18F]HX4 and [18F]FDG-PET/CT imaging.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Female; Fluorodeoxyglucose F18; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Image Processing, Computer-Assisted; Imidazoles; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Triazoles | 2014 |
Automated radiosynthesis of GMP quality [18F]HX4 for PET imaging of hypoxia.
Topics: Automation; Hypoxia; Nitroimidazoles; Positron-Emission Tomography; Quality Control; Radiochemistry; Triazoles | 2015 |
Feasibility and repeatability of PET with the hypoxia tracer [(18)F]HX4 in oesophageal and pancreatic cancer.
Topics: Aged; Esophageal Neoplasms; Feasibility Studies; Female; Humans; Hypoxia; Imidazoles; Male; Middle Aged; Pancreatic Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Triazoles | 2015 |
Comparison of [18F]-FMISO, [18F]-FAZA and [18F]-HX4 for PET imaging of hypoxia--a simulation study.
Topics: Humans; Hypoxia; Imidazoles; Misonidazole; Models, Theoretical; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Triazoles | 2015 |
Imaging of tumour hypoxia and metabolism in patients with head and neck squamous cell carcinoma.
Topics: Aged; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Imidazoles; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Triazoles | 2015 |
In vitro and in vivo evaluation of technetium-99m-labeled propylene amine oxime complexes containing nitroimidazole and nitrotriazole groups as hypoxia markers.
Topics: Animals; Cell Line, Tumor; Hypoxia; Male; Mice; Nitroimidazoles; Organotechnetium Compounds; Oximes; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution; Triazoles | 2016 |
The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.
Topics: Animals; Azepines; Carbonic Anhydrase IX; Cell Line, Tumor; Cluster Analysis; Disease Models, Animal; Female; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Neovascularization, Pathologic; Promoter Regions, Genetic; Protein Binding; Spheroids, Cellular; Transcriptome; Triazoles; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2017 |
Investigation of cobalt(iii)-triazole systems as prototypes for hypoxia-activated drug delivery.
Topics: Ascorbic Acid; Cobalt; Coordination Complexes; Drug Delivery Systems; Hypoxia; Ligands; Models, Biological; Molecular Structure; Oxidation-Reduction; Oxygen; Prodrugs; Triazoles | 2016 |
Neonatal caffeine induces sex-specific developmental plasticity of the hypoxic respiratory chemoreflex in adult rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Animals, Newborn; Caffeine; Carotid Body; Central Nervous System Stimulants; Female; Gene Expression; Hypoxia; Male; Neural Inhibition; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Reflex; Respiration; RNA, Messenger; Sex Characteristics; Triazines; Triazoles; Tyrosine 3-Monooxygenase | 2008 |
Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Biological Clocks; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Fourier Analysis; Hippocampus; Hypoxia; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Thioinosine; Time Factors; Triazines; Triazoles | 2009 |
Effects of 17beta-estradiol on rat urinary bladder: gender differences in anoxia-glucopenia and reperfusion damage.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Glucose; Hypoxia; In Vitro Techniques; Injections, Subcutaneous; Male; Muscle Contraction; Neuroprotective Agents; Nitriles; Rats; Rats, Wistar; Reperfusion Injury; Sex Factors; Testosterone; Time Factors; Triazoles; Urinary Bladder; Urinary Bladder Diseases | 2009 |
Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Blood Gas Analysis; Blood Glucose; Female; Fetus; Hydrogen-Ion Concentration; Hypoxia; Insulin; Lactates; Pregnancy; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sheep; Triazines; Triazoles; Xanthines | 2009 |
ATP protects, by way of receptor-mediated mechanisms, against hypoxia-induced injury in renal proximal tubules.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Hemolysis; Hypotonic Solutions; Hypoxia; Kidney Tubules, Proximal; Kinetics; L-Lactate Dehydrogenase; Male; Potassium; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Triazoles | 2003 |
Altered production of nitric oxide and reactive oxygen species in rat nodose ganglion neurons during acute hypoxia.
Topics: Acute Disease; Animals; Female; Fluoresceins; Fluorescent Dyes; Hypoxia; Immunohistochemistry; In Vitro Techniques; Male; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nodose Ganglion; Rats; Rats, Wistar; Reactive Oxygen Species; Subcellular Fractions; Triazoles | 2003 |
Mesenteric microvascular inflammatory responses to systemic hypoxia are mediated by PAF and LTB4.
Topics: Animals; Azepines; Capillary Permeability; Cell Adhesion; Fluorescence; Hypoxia; Leukocytes; Leukotriene B4; Male; Microcirculation; Oxidants; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Rhodamines; Splanchnic Circulation; Triazoles; Vasculitis | 2003 |
Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Electric Stimulation; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; Hypoxia; In Vitro Techniques; Ischemic Preconditioning; Male; Oxygen; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Time Factors; Triazines; Triazoles; Xanthines | 2003 |
The effect of caffeine on peripheral vascular resistance in isolated perfused guinea pig hind limbs.
Topics: Adenosine; Animals; Caffeine; Dose-Response Relationship, Drug; Female; Flavins; Guinea Pigs; Hindlimb; Hypoxia; Iliac Artery; Iloprost; Male; Nitrogen; Norepinephrine; Perfusion; Triazines; Triazoles; Vascular Resistance; Vasoconstriction; Vasodilation | 2003 |
LTP-induced depression of response to hypoxia in hippocampus: effects of adenosine receptor activation.
Topics: Adenosine; Animals; Electric Stimulation; Hippocampus; Hypoxia; In Vitro Techniques; Long-Term Potentiation; Male; Membrane Potentials; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Triazines; Triazoles | 2003 |
The role of platelet activating factor in a neonatal piglet model of necrotising enterocolitis.
Topics: Animals; Animals, Newborn; Azepines; Blood Gas Analysis; Blood Pressure; Enterocolitis, Necrotizing; Hypoxia; Intestinal Mucosa; Lipopolysaccharides; Mesenteric Arteries; Models, Animal; Platelet Activating Factor; Regional Blood Flow; Swine; Triazoles; Vascular Resistance | 2004 |
Preparation and preliminary biological evaluation of a 177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Fibrosarcoma; Hypoxia; Lutetium; Mice; Neoplasms; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Triazoles | 2004 |
Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia.
Topics: 5'-Nucleotidase; Adenosine; Animals; Capillary Permeability; Hypoxia; Lung; Mice; Triazines; Triazoles | 2004 |
Adenosine A2A-receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs.
Topics: Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Blood Pressure; Body Temperature; Carbon Dioxide; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Oxygen; Receptor, Adenosine A2A; Respiration; Sheep; Tidal Volume; Time Factors; Triazines; Triazoles; Xanthines | 2005 |
Adenosine concentration in the porcine coronary artery wall and A2A receptor involvement in hypoxia-induced vasodilatation.
Topics: Acetamides; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Glucose; Hypoxia; In Vitro Techniques; Lactates; Purines; Pyruvic Acid; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Swine; Triazines; Triazoles; Vasodilation | 2006 |
A3 adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro.
Topics: Action Potentials; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Hippocampus; Hypoglycemia; Hypoxia; Male; Pyridines; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Synaptic Transmission; Time Factors; Triazoles | 2006 |
Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.
Topics: Adenosine; Animals; Caffeine; Carotid Body; Catecholamines; Central Nervous System Stimulants; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Hypoxia; Immunohistochemistry; Male; Potassium; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Presynaptic; Respiratory Mechanics; Triazines; Triazoles; Xanthines | 2006 |
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic; Sodium Channel Blockers; Tetrodotoxin; Triazines; Triazoles; Xanthines | 2007 |
Platelet-activating factor stimulates ovine foetal pulmonary vascular smooth muscle cell proliferation: role of nuclear factor-kappa B and cyclin-dependent kinases.
Topics: Animals; Azepines; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Female; Flavonoids; Hypoxia; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; Oxygen; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Sheep; Structure-Activity Relationship; Triazoles | 2008 |
Attenuation of hypoxia-induced increases in ventilation by adenosine antagonists in rhesus monkeys.
Topics: Adenosine; Animals; Hypoxia; Macaca mulatta; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinazolines; Respiration; Rolipram; Triazoles | 1995 |
Hypoxia induces PMN adherence to umbilical vein endothelium.
Topics: Antibodies, Monoclonal; Azepines; Cell Adhesion; Culture Techniques; Endothelium, Vascular; Humans; Hypoxia; Intercellular Adhesion Molecule-1; Microscopy, Electron, Scanning; Neutrophil Activation; Neutrophils; Oleic Acid; Oleic Acids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Umbilical Veins | 1995 |
Effects of cytochrome P-450 inhibitors on ionic currents in isolated rat type I carotid body cells.
Topics: Animals; Antifungal Agents; Calcium Channel Blockers; Carotid Body; Cell Separation; Cells, Cultured; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Electric Conductivity; Hypoxia; Imidazoles; Ions; Miconazole; Potassium Channel Blockers; Rats; Rats, Wistar; Reference Values; Triazoles | 1996 |
Is cytochrome P-450 involved in hypoxic inhibition of K+ currents in rat type I carotid body cells?
Topics: Action Potentials; Animals; Carotid Body; Cell Hypoxia; Cells, Cultured; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hypoxia; Ion Transport; Miconazole; Nerve Tissue Proteins; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; Triazoles | 1996 |
Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood-Brain Barrier; Erythrocytes; Hypoxia; Laser-Doppler Flowmetry; Male; Parietal Lobe; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation | 1998 |
Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Gas Analysis; Hydrogen-Ion Concentration; Hypoxia; Male; Muscle, Skeletal; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Respiration; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 1999 |
Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Farnesol; Hypoxia; In Vitro Techniques; Indoles; Maleimides; Nitric Oxide; Prostaglandin Antagonists; Protein Kinase C; Pulmonary Artery; Pulmonary Circulation; Rabbits; Triazoles; Vasoconstriction | 1999 |
Oxygen delivery and oxygen consumption in rat hindlimb during systemic hypoxia: role of adenosine.
Topics: Adenosine; Animals; Hemodynamics; Hindlimb; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxygen Consumption; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Vital Capacity; Xanthines | 2001 |
[1.3-Dipolar cycloaddition products of 8-azidotetrazol[1,5a][1,8]naphthyridines with alkynes].
Topics: Alkynes; Animals; Cyclization; Hypoxia; Methods; Mice; Naphthyridines; Triazoles | 1978 |
PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats.
Topics: Animals; Azepines; Endothelins; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Circulation; Rats; Triazoles; Vasoconstriction | 1992 |
Intact lung cytochrome P-450 is not required for hypoxic pulmonary vasoconstriction.
Topics: Angiotensin II; Animals; Aorta; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electric Stimulation; Hypoxia; In Vitro Techniques; Lung; Male; Metyrapone; Papillary Muscles; Pulmonary Circulation; Rabbits; Rats; Triazoles; Vasoconstriction | 1992 |
Pulmonary vascular reactivity: effect of PAF and PAF antagonists.
Topics: Angiotensin II; Animals; Azepines; Hypoxia; In Vitro Techniques; Male; Phospholipid Ethers; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Edema; Quinolinium Compounds; Rats; Rats, Sprague-Dawley; Triazoles; Vasoconstriction; Vasodilation | 1992 |
[Effects of the PAF antagonist WEB 2086 on hypoxia and angiotensin II-induced pulmonary vasoconstriction in the isolated perfused rat lung].
Topics: Angiotensin II; Animals; Azepines; Hypoxia; Organ Culture Techniques; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Rats; Triazoles; Vasoconstriction | 1991 |
Sustained effects of platelet-activating factor infusion in piglets.
Topics: Animals; Animals, Newborn; Azepines; Female; Hypoxia; Infusions, Intravenous; Male; Platelet Activating Factor; Pulmonary Circulation; Quinolinium Compounds; Swine; Triazoles; Vasoconstriction | 1991 |
Arachidonic acid causes cyclooxygenase-dependent and -independent pulmonary vasodilation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hypoxia; In Vitro Techniques; Male; Perfusion; Prostaglandin-Endoperoxide Synthases; Pulmonary Circulation; Rats; Rats, Inbred Strains; Thromboxane B2; Triazoles; Vasodilation | 1990 |
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Platelet-activating factor: evidence against a role in hypoxic pulmonary vasoconstriction.
Topics: Animals; Azepines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Injections, Intravenous; Male; Platelet Activating Factor; Pulmonary Circulation; Swine; Triazoles; Vascular Resistance; Vasoconstriction | 1990 |
Hypoxia causes ischemic bowel necrosis in rats: the role of platelet-activating factor (PAF-acether).
Topics: Animals; Azepines; Enterocolitis, Pseudomembranous; Hypoxia; Intestine, Small; Male; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Inbred Strains; Triazoles | 1990 |
Evidence against a role for platelet-activating factor in hypoxic pulmonary vasoconstriction in the rat.
Topics: Animals; Azepines; Diterpenes; Ginkgolides; Hypoxia; Lactones; Male; Platelet Activating Factor; Pulmonary Circulation; Rats; Rats, Inbred Strains; Triazines; Triazoles; Vasoconstriction | 1989 |
A comparison of the cobalt, methylene blue, zinc, arsenite and amino triazole effect on erythropoietin production.
Topics: Animals; Arsenic; Biological Assay; Cobalt; Erythropoietin; Female; Hypoxia; Iron; Iron Isotopes; Male; Methylene Blue; Mice; Polycythemia; Rabbits; Stimulation, Chemical; Triazoles; Zinc | 1973 |