Page last updated: 2024-08-23

tobramycin and Aging

tobramycin has been researched along with Aging in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crass, RL; Pai, MP1
Allegaert, K; Brussee, JM; Danhof, M; De Cock, RF; de Hoog, M; Knibbe, CA; Mulla, H; Sherwin, CM; van den Anker, JN1
Holford, N; Kirkpatrick, C; Matthews, I1
Yaffe, SJ1
Bauer, LA; Blouin, RA1
Cipolle, RJ; Seifert, RD; Strate, RG; Zaske, DE1
Wasfi, IA1
Bakker, W; Heijerman, HG; Touw, DJ; Vinks, AA1
Dormans, JA; Dortant, PM; Peters-Volleberg, GW; Speijers, GJ1
Amorusi, P; Dowell, JA; Korth-Bradley, J; Milisci, M; Tantillo, K; Tse, S1
Bertino, JS; Etzel, JV; Nafziger, AN1
Alvestrand, A; Hjelte, L; Larsson, M; Malmborg, AS; Strandvik, B1
Higa, GM; Murray, WE1

Reviews

1 review(s) available for tobramycin and Aging

ArticleYear
Antimicrobial therapy and the neonate.
    Obstetrics and gynecology, 1981, Volume: 58, Issue:5 Suppl

    Topics: Absorption; Aging; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Biological Availability; Biotransformation; Cephalosporins; Chloramphenicol; Gentamicins; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kidney; Penicillins; Protein Binding; Tobramycin

1981

Trials

1 trial(s) available for tobramycin and Aging

ArticleYear
Evaluating possible pharmacokinetic interactions between tobramycin, piperacillin, and a combination of piperacillin and tazobactam in patients with various degrees of renal impairment.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:9

    Topics: Adult; Aged; Aging; Anti-Bacterial Agents; Area Under Curve; beta-Lactamase Inhibitors; Creatinine; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam; Tobramycin

2001

Other Studies

11 other study(ies) available for tobramycin and Aging

ArticleYear
Optimizing Estimated Glomerular Filtration Rate to Support Adult to Pediatric Pharmacokinetic Bridging Studies in Patients with Cystic Fibrosis.
    Clinical pharmacokinetics, 2019, Volume: 58, Issue:10

    Topics: Adolescent; Adult; Aging; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Female; Glomerular Filtration Rate; Humans; Infant; Male; Middle Aged; Models, Biological; Tobramycin; Young Adult

2019
Simultaneous pharmacokinetic modeling of gentamicin, tobramycin and vancomycin clearance from neonates to adults: towards a semi-physiological function for maturation in glomerular filtration.
    Pharmaceutical research, 2014, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Aging; Body Weight; Child; Child, Preschool; Creatinine; Gentamicins; Glomerular Filtration Rate; Humans; Infant; Infant, Newborn; Metabolic Clearance Rate; Models, Biological; Tobramycin; Vancomycin

2014
Quantitative justification for target concentration intervention--parameter variability and predictive performance using population pharmacokinetic models for aminoglycosides.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:1

    Topics: Adult; Aged; Aging; Aminoglycosides; Anti-Bacterial Agents; Body Weight; Creatinine; Female; Gentamicins; Humans; Kidney; Male; Middle Aged; Models, Chemical; Predictive Value of Tests; Tobramycin

2004
Influence of age on tobramycin pharmacokinetics in patients with normal renal function.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:5

    Topics: Adult; Aged; Aging; Anti-Bacterial Agents; Bacterial Infections; Female; Half-Life; Humans; Kidney; Kinetics; Male; Middle Aged; Tobramycin

1981
Systematically individualizing tobramycin dosage regimens.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Aged; Aging; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Female; Humans; Infant; Kinetics; Male; Middle Aged; Time Factors; Tobramycin

1980
The effect of endotoxin on tobramycin pharmacokinetics in young and aged rats.
    Pharmacology, 1993, Volume: 47, Issue:4

    Topics: Aging; Animals; Body Weight; Endotoxins; Escherichia coli; Half-Life; Injections, Intraperitoneal; Male; Rats; Rats, Wistar; Tobramycin

1993
Validation of tobramycin monitoring in adolescent and adult patients with cystic fibrosis.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aging; Cystic Fibrosis; Drug Administration Schedule; Drug Delivery Systems; Drug Monitoring; Female; Humans; Male; Models, Biological; Predictive Value of Tests; Reproducibility of Results; Retrospective Studies; Tobramycin

1993
Ototoxicity of tobramycin in young adult and old rats.
    Toxicology and applied pharmacology, 1996, Volume: 136, Issue:1

    Topics: Aging; Animals; Anti-Bacterial Agents; Cochlea; Dose-Response Relationship, Drug; Female; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Injections, Subcutaneous; Microscopy, Electron, Scanning; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Tobramycin

1996
Variation in the pharmacokinetics of gentamicin and tobramycin in patients with pleural effusions and hypoalbuminemia.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:3

    Topics: Aged; Aging; Body Weight; Female; Fluorescence Polarization Immunoassay; Gentamicins; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pleural Effusion; Prospective Studies; Regression Analysis; Serum Albumin; Tobramycin

1992
Renal function in rats with essential fatty acid deficiency.
    Clinical science (London, England : 1979), 1990, Volume: 79, Issue:4

    Topics: Aging; Animals; Fatty Acids, Essential; Female; Glomerular Filtration Rate; Kidney; Phospholipids; Potassium; Rats; Rats, Inbred Strains; Sodium; Time Factors; Tobramycin; Urea

1990
Alterations in aminoglycoside pharmacokinetics in patients with cancer.
    Clinical pharmacy, 1987, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Aging; Anti-Bacterial Agents; Child; Child, Preschool; Female; Gentamicins; Humans; Infant; Leukocyte Count; Male; Neoplasms; Serum Albumin; Sex Factors; Tobramycin

1987