thyroxine and ADDH
thyroxine has been researched along with ADDH in 26 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of maternal levothyroxine treatment during pregnancy remains unclear." | 8.12 | Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study. ( Cheung, CL; Cheung, ECL; Ge, GM; Ip, P; Kung, AWC; Leung, WC; Li, GHY; Man, KKC; Wong, ICK, 2022) |
| "Severe iodine deficiency during pregnancy can cause intellectual disability, presumably through inadequate placental transfer of maternal thyroid hormone to the fetus." | 7.96 | Maternal Iodine Status During Pregnancy Is Not Consistently Associated with Attention-Deficit Hyperactivity Disorder or Autistic Traits in Children. ( Bath, SC; Dineva, M; Fano, E; Guxens, M; Ibarluzea, JM; Korevaar, TIM; Levie, D; Llop, S; Murcia, M; Peeters, RP; Rayman, MP; Sunyer, J; Tiemeier, H, 2020) |
| " Thyroxine supplementation during pregnancy requires monitoring to avoid overtreatment." | 5.34 | Controlled Antenatal Thyroid Screening II: Effect of Treating Maternal Suboptimal Thyroid Function on Child Behavior. ( Channon, S; Dayan, C; Draman, MS; Gregory, JW; Hales, C; Langley, K; Lazarus, JH; Ludgate, M; McEwan, K; Muller, I; Okosieme, O; Rees, DA; Taylor, PN; Thapar, A, 2020) |
| "The influence of maternal levothyroxine treatment during pregnancy remains unclear." | 4.12 | Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study. ( Cheung, CL; Cheung, ECL; Ge, GM; Ip, P; Kung, AWC; Leung, WC; Li, GHY; Man, KKC; Wong, ICK, 2022) |
| "Severe iodine deficiency during pregnancy can cause intellectual disability, presumably through inadequate placental transfer of maternal thyroid hormone to the fetus." | 3.96 | Maternal Iodine Status During Pregnancy Is Not Consistently Associated with Attention-Deficit Hyperactivity Disorder or Autistic Traits in Children. ( Bath, SC; Dineva, M; Fano, E; Guxens, M; Ibarluzea, JM; Korevaar, TIM; Levie, D; Llop, S; Murcia, M; Peeters, RP; Rayman, MP; Sunyer, J; Tiemeier, H, 2020) |
| "All patients had central hypothyroidism, and twelve were treated with levothyroxine." | 3.83 | Mild deficits in attentional control in patients with the IGSF1 deficiency syndrome. ( Andela, CD; Biermasz, NR; Fliers, E; Joustra, SD; Middelkoop, HA; Oostdijk, W; Pereira, AM; van Trotsenburg, AS; Wit, JM, 2016) |
| "Maternal hypothyroxinemia (n = 127) in early pregnancy was associated with higher scores for ADHD symptoms in children at 8 years of age after adjustments for child and maternal factors (ie, sex, ethnicity, maternal age, maternal educational level, and income) (increase in ADHD scores, 7% [95% CI, 0." | 3.81 | Maternal Mild Thyroid Hormone Insufficiency in Early Pregnancy and Attention-Deficit/Hyperactivity Disorder Symptoms in Children. ( Ghassabian, A; Hofman, A; Jaddoe, VW; Modesto, T; Peeters, RP; Tiemeier, H; Verhulst, FC, 2015) |
| "We failed to find evidence of generalized resistance to thyroid hormone." | 1.29 | ADHD and thyroid abnormalities: a research note. ( Biederman, J; Guite, J; Harding, M; Spencer, T; Wilens, T, 1995) |
Research
Studies (26)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 5 (19.23) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Rotem, RS | 1 |
| Chodick, G | 1 |
| Davidovitch, M | 1 |
| Bellavia, A | 1 |
| Weisskopf, MG | 1 |
| Ge, GM | 1 |
| Cheung, ECL | 1 |
| Man, KKC | 1 |
| Ip, P | 1 |
| Leung, WC | 1 |
| Li, GHY | 1 |
| Kung, AWC | 1 |
| Cheung, CL | 1 |
| Wong, ICK | 1 |
| Hales, C | 1 |
| Taylor, PN | 1 |
| Channon, S | 1 |
| McEwan, K | 1 |
| Thapar, A | 1 |
| Langley, K | 1 |
| Muller, I | 1 |
| Draman, MS | 1 |
| Dayan, C | 1 |
| Gregory, JW | 1 |
| Okosieme, O | 1 |
| Lazarus, JH | 1 |
| Rees, DA | 1 |
| Ludgate, M | 1 |
| Levie, D | 1 |
| Bath, SC | 1 |
| Guxens, M | 1 |
| Korevaar, TIM | 1 |
| Dineva, M | 1 |
| Fano, E | 1 |
| Ibarluzea, JM | 1 |
| Llop, S | 1 |
| Murcia, M | 1 |
| Rayman, MP | 1 |
| Sunyer, J | 2 |
| Peeters, RP | 2 |
| Tiemeier, H | 2 |
| Albrecht, D | 1 |
| Ittermann, T | 1 |
| Thamm, M | 1 |
| Grabe, HJ | 1 |
| Bahls, M | 1 |
| Völzke, H | 1 |
| Kuppili, PP | 1 |
| Pattanayak, RD | 1 |
| Sagar, R | 1 |
| Mehta, M | 1 |
| Vivekanandhan, S | 1 |
| Langrock, C | 1 |
| Hebebrand, J | 1 |
| Radowksi, K | 1 |
| Hamelmann, E | 1 |
| Lücke, T | 1 |
| Holtmann, M | 2 |
| Legenbauer, T | 1 |
| Schmidt, B | 1 |
| Frank, M | 1 |
| Jöckel, KH | 1 |
| Reinehr, T | 1 |
| Çatli, G | 1 |
| Fujisawa, H | 1 |
| Kirbiyik, Ö | 1 |
| Mimoto, MS | 1 |
| Gençpinar, P | 1 |
| Özdemir, TR | 1 |
| Dündar, BN | 1 |
| Dumitrescu, AM | 1 |
| Fetene, DM | 1 |
| Betts, KS | 1 |
| Alati, R | 1 |
| Modesto, T | 1 |
| Jaddoe, VW | 1 |
| Hofman, A | 1 |
| Verhulst, FC | 1 |
| Ghassabian, A | 1 |
| Joustra, SD | 2 |
| Andela, CD | 1 |
| Oostdijk, W | 2 |
| van Trotsenburg, AS | 2 |
| Fliers, E | 2 |
| Wit, JM | 2 |
| Pereira, AM | 2 |
| Middelkoop, HA | 1 |
| Biermasz, NR | 2 |
| Heinen, CA | 1 |
| Schoenmakers, N | 1 |
| Bonomi, M | 1 |
| Ballieux, BE | 1 |
| Turgeon, MO | 1 |
| Bernard, DJ | 1 |
| Losekoot, M | 1 |
| Persani, L | 1 |
| Burman, KD | 1 |
| Simic, N | 1 |
| Asztalos, EV | 1 |
| Rovet, J | 2 |
| Duketis, E | 1 |
| Goth, K | 1 |
| Poustka, L | 1 |
| Boelte, S | 1 |
| Banerjee, J | 1 |
| Bhojani, S | 1 |
| Emcy, N | 1 |
| Anzai, R | 1 |
| Adachi, M | 1 |
| Sho, N | 1 |
| Muroya, K | 1 |
| Asakura, Y | 1 |
| Onigata, K | 1 |
| Stein, MA | 1 |
| Weiss, RE | 1 |
| Alvarez-Pedrerol, M | 1 |
| Ribas-Fitó, N | 1 |
| Torrent, M | 1 |
| Julvez, J | 1 |
| Ferrer, C | 1 |
| Bossowski, AT | 1 |
| Reddy, V | 1 |
| Perry, LA | 1 |
| Johnston, LB | 1 |
| Banerjee, K | 1 |
| Blair, JC | 1 |
| Savage, MO | 1 |
| Spencer, T | 1 |
| Biederman, J | 1 |
| Wilens, T | 1 |
| Guite, J | 1 |
| Harding, M | 1 |
| Hauser, P | 1 |
| Zametkin, AJ | 1 |
| Martinez, P | 1 |
| Vitiello, B | 1 |
| Matochik, JA | 1 |
| Mixson, AJ | 1 |
| Weintraub, BD | 1 |
| Alvarez, M | 1 |
| Ghazi, AA | 1 |
| Refetoff, S | 1 |
| McCune, N | 1 |
| Ritchie, K | 1 |
| Soldin, OP | 1 |
| Nandedkar, AK | 1 |
| Japal, KM | 1 |
| Stein, M | 1 |
| Mosee, S | 1 |
| Magrab, P | 1 |
| Lai, S | 1 |
| Lamm, SH | 1 |
Reviews
1 review available for thyroxine and ADDH
| Article | Year |
|---|---|
Long-term 3,5,3'-triiodothyroacetic acid therapy in a child with hyperthyroidism caused by thyroid hormone resistance: pharmacological study and therapeutic recommendations.
Topics: Adolescent; Adult; Atrial Premature Complexes; Attention Deficit Disorder with Hyperactivity; Child; | 2012 |
Trials
2 trials available for thyroxine and ADDH
| Article | Year |
|---|---|
Controlled Antenatal Thyroid Screening II: Effect of Treating Maternal Suboptimal Thyroid Function on Child Behavior.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Biomarkers; Case-Control Studies; Child; Child | 2020 |
Clinical and endocrine features and long-term outcome of Graves' disease in early childhood.
Topics: Age of Onset; Antithyroid Agents; Attention Deficit Disorder with Hyperactivity; Carbimazole; Child; | 2007 |
Other Studies
23 other studies available for thyroxine and ADDH
| Article | Year |
|---|---|
Maternal Thyroid Anomalies and Attention-Deficit Hyperactivity Disorder in Progeny.
Topics: Attention Deficit Disorder with Hyperactivity; Female; Humans; Mothers; Pregnancy; Prenatal Exposure | 2022 |
Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study.
Topics: Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Cohort Studies; Female; Hum | 2022 |
Maternal Iodine Status During Pregnancy Is Not Consistently Associated with Attention-Deficit Hyperactivity Disorder or Autistic Traits in Children.
Topics: Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Child, Preschool; Creatinin | 2020 |
The association between thyroid function biomarkers and attention deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cross-Sectional Studies; Female; H | 2020 |
Thyroid and Cortisol hormones in Attention Deficit Hyperactivity Disorder: A case-control study.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Biomarkers; Case-Control Studies; Child; | 2017 |
Thyroid Hormone Status in Overweight Children with Attention Deficit/Hyperactivity Disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Cross-Sectional Studies; Female; Humans; Male; | 2018 |
A Novel Homozygous Selenocysteine Insertion Sequence Binding Protein 2 (SECISBP2, SBP2) Gene Mutation in a Turkish Boy.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Humans; Male; Muscle Weakness; Mutagenesis, In | 2018 |
Maternal Prenatal Thyroid Function and Offspring ADHD: Findings From the ALSPAC Cohort.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Iodide Pero | 2018 |
Maternal Mild Thyroid Hormone Insufficiency in Early Pregnancy and Attention-Deficit/Hyperactivity Disorder Symptoms in Children.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Female; Follow-Up Studies; Gestational | 2015 |
Mild deficits in attentional control in patients with the IGSF1 deficiency syndrome.
Topics: Adolescent; Adult; Aged; Attention; Attention Deficit Disorder with Hyperactivity; Case-Control Stud | 2016 |
IGSF1 Deficiency: Lessons From an Extensive Case Series and Recommendations for Clinical Management.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Attention Deficit Disorder with Hyperactivity; Child; Ch | 2016 |
Commentary: discordant measurements of serum triiodothyronine (T4), thyroxine (T3) and thyroid-stimulating hormone (TSH).
Topics: Antibodies, Heterophile; Attention Deficit Disorder with Hyperactivity; Female; Humans; Immunoassay; | 2008 |
Impact of neonatal thyroid hormone insufficiency and medical morbidity on infant neurodevelopment and attention following preterm birth.
Topics: Attention Deficit Disorder with Hyperactivity; Child Development; Developmental Disabilities; Humans | 2009 |
Severe affective and behavioral dysregulation in youth is associated with increased serum TSH.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Anxiety Disorders; Attention Deficit Disord | 2010 |
Co-existence of ADHD, autoimmune hypothyroidism and pituitary macroadenoma presenting in a behaviour clinic: a case report and brief review of the literature.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Autoimmune Diseases; Community Mental Hea | 2011 |
Thyroid function tests and neurocognitive functioning in children referred for attention deficit/hyperactivity disorder.
Topics: Adolescent; Affect; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Behavior; C | 2003 |
TSH concentration within the normal range is associated with cognitive function and ADHD symptoms in healthy preschoolers.
Topics: Attention Deficit Disorder with Hyperactivity; Child, Preschool; Cognition Disorders; Cross-Sectiona | 2007 |
ADHD and thyroid abnormalities: a research note.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Diagnosis, Diffe | 1995 |
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Drug Resistance; Female; Humans; Male; | 1993 |
Thyroid hormone and attention in school-age children with congenital hypothyroidism.
Topics: Attention; Attention Deficit Disorder with Hyperactivity; Child; Congenital Hypothyroidism; Female; | 1996 |
Evaluation of pituitary and peripheral tissue markers of thyroid hormone action in an Iranian family with resistance to thyroid hormone.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Ferritins; Humans; Iran; Male; Pedigree; | 1996 |
ADHD/thyroid dysfunction.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Male; Neurocogniti | 1997 |
Newborn thyroxine levels and childhood ADHD.
Topics: Age Factors; Attention Deficit Disorder with Hyperactivity; Biomarkers; Case-Control Studies; Child; | 2002 |