Page last updated: 2024-11-06

thyroxine and ADDH

thyroxine has been researched along with ADDH in 26 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"The influence of maternal levothyroxine treatment during pregnancy remains unclear."8.12Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study. ( Cheung, CL; Cheung, ECL; Ge, GM; Ip, P; Kung, AWC; Leung, WC; Li, GHY; Man, KKC; Wong, ICK, 2022)
"Severe iodine deficiency during pregnancy can cause intellectual disability, presumably through inadequate placental transfer of maternal thyroid hormone to the fetus."7.96Maternal Iodine Status During Pregnancy Is Not Consistently Associated with Attention-Deficit Hyperactivity Disorder or Autistic Traits in Children. ( Bath, SC; Dineva, M; Fano, E; Guxens, M; Ibarluzea, JM; Korevaar, TIM; Levie, D; Llop, S; Murcia, M; Peeters, RP; Rayman, MP; Sunyer, J; Tiemeier, H, 2020)
" Thyroxine supplementation during pregnancy requires monitoring to avoid overtreatment."5.34Controlled Antenatal Thyroid Screening II: Effect of Treating Maternal Suboptimal Thyroid Function on Child Behavior. ( Channon, S; Dayan, C; Draman, MS; Gregory, JW; Hales, C; Langley, K; Lazarus, JH; Ludgate, M; McEwan, K; Muller, I; Okosieme, O; Rees, DA; Taylor, PN; Thapar, A, 2020)
"The influence of maternal levothyroxine treatment during pregnancy remains unclear."4.12Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study. ( Cheung, CL; Cheung, ECL; Ge, GM; Ip, P; Kung, AWC; Leung, WC; Li, GHY; Man, KKC; Wong, ICK, 2022)
"Severe iodine deficiency during pregnancy can cause intellectual disability, presumably through inadequate placental transfer of maternal thyroid hormone to the fetus."3.96Maternal Iodine Status During Pregnancy Is Not Consistently Associated with Attention-Deficit Hyperactivity Disorder or Autistic Traits in Children. ( Bath, SC; Dineva, M; Fano, E; Guxens, M; Ibarluzea, JM; Korevaar, TIM; Levie, D; Llop, S; Murcia, M; Peeters, RP; Rayman, MP; Sunyer, J; Tiemeier, H, 2020)
"All patients had central hypothyroidism, and twelve were treated with levothyroxine."3.83Mild deficits in attentional control in patients with the IGSF1 deficiency syndrome. ( Andela, CD; Biermasz, NR; Fliers, E; Joustra, SD; Middelkoop, HA; Oostdijk, W; Pereira, AM; van Trotsenburg, AS; Wit, JM, 2016)
"Maternal hypothyroxinemia (n = 127) in early pregnancy was associated with higher scores for ADHD symptoms in children at 8 years of age after adjustments for child and maternal factors (ie, sex, ethnicity, maternal age, maternal educational level, and income) (increase in ADHD scores, 7% [95% CI, 0."3.81Maternal Mild Thyroid Hormone Insufficiency in Early Pregnancy and Attention-Deficit/Hyperactivity Disorder Symptoms in Children. ( Ghassabian, A; Hofman, A; Jaddoe, VW; Modesto, T; Peeters, RP; Tiemeier, H; Verhulst, FC, 2015)
"We failed to find evidence of generalized resistance to thyroid hormone."1.29ADHD and thyroid abnormalities: a research note. ( Biederman, J; Guite, J; Harding, M; Spencer, T; Wilens, T, 1995)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (19.23)18.2507
2000's6 (23.08)29.6817
2010's10 (38.46)24.3611
2020's5 (19.23)2.80

Authors

AuthorsStudies
Rotem, RS1
Chodick, G1
Davidovitch, M1
Bellavia, A1
Weisskopf, MG1
Ge, GM1
Cheung, ECL1
Man, KKC1
Ip, P1
Leung, WC1
Li, GHY1
Kung, AWC1
Cheung, CL1
Wong, ICK1
Hales, C1
Taylor, PN1
Channon, S1
McEwan, K1
Thapar, A1
Langley, K1
Muller, I1
Draman, MS1
Dayan, C1
Gregory, JW1
Okosieme, O1
Lazarus, JH1
Rees, DA1
Ludgate, M1
Levie, D1
Bath, SC1
Guxens, M1
Korevaar, TIM1
Dineva, M1
Fano, E1
Ibarluzea, JM1
Llop, S1
Murcia, M1
Rayman, MP1
Sunyer, J2
Peeters, RP2
Tiemeier, H2
Albrecht, D1
Ittermann, T1
Thamm, M1
Grabe, HJ1
Bahls, M1
Völzke, H1
Kuppili, PP1
Pattanayak, RD1
Sagar, R1
Mehta, M1
Vivekanandhan, S1
Langrock, C1
Hebebrand, J1
Radowksi, K1
Hamelmann, E1
Lücke, T1
Holtmann, M2
Legenbauer, T1
Schmidt, B1
Frank, M1
Jöckel, KH1
Reinehr, T1
Çatli, G1
Fujisawa, H1
Kirbiyik, Ö1
Mimoto, MS1
Gençpinar, P1
Özdemir, TR1
Dündar, BN1
Dumitrescu, AM1
Fetene, DM1
Betts, KS1
Alati, R1
Modesto, T1
Jaddoe, VW1
Hofman, A1
Verhulst, FC1
Ghassabian, A1
Joustra, SD2
Andela, CD1
Oostdijk, W2
van Trotsenburg, AS2
Fliers, E2
Wit, JM2
Pereira, AM2
Middelkoop, HA1
Biermasz, NR2
Heinen, CA1
Schoenmakers, N1
Bonomi, M1
Ballieux, BE1
Turgeon, MO1
Bernard, DJ1
Losekoot, M1
Persani, L1
Burman, KD1
Simic, N1
Asztalos, EV1
Rovet, J2
Duketis, E1
Goth, K1
Poustka, L1
Boelte, S1
Banerjee, J1
Bhojani, S1
Emcy, N1
Anzai, R1
Adachi, M1
Sho, N1
Muroya, K1
Asakura, Y1
Onigata, K1
Stein, MA1
Weiss, RE1
Alvarez-Pedrerol, M1
Ribas-Fitó, N1
Torrent, M1
Julvez, J1
Ferrer, C1
Bossowski, AT1
Reddy, V1
Perry, LA1
Johnston, LB1
Banerjee, K1
Blair, JC1
Savage, MO1
Spencer, T1
Biederman, J1
Wilens, T1
Guite, J1
Harding, M1
Hauser, P1
Zametkin, AJ1
Martinez, P1
Vitiello, B1
Matochik, JA1
Mixson, AJ1
Weintraub, BD1
Alvarez, M1
Ghazi, AA1
Refetoff, S1
McCune, N1
Ritchie, K1
Soldin, OP1
Nandedkar, AK1
Japal, KM1
Stein, M1
Mosee, S1
Magrab, P1
Lai, S1
Lamm, SH1

Reviews

1 review available for thyroxine and ADDH

ArticleYear
Long-term 3,5,3'-triiodothyroacetic acid therapy in a child with hyperthyroidism caused by thyroid hormone resistance: pharmacological study and therapeutic recommendations.
    Thyroid : official journal of the American Thyroid Association, 2012, Volume: 22, Issue:10

    Topics: Adolescent; Adult; Atrial Premature Complexes; Attention Deficit Disorder with Hyperactivity; Child;

2012

Trials

2 trials available for thyroxine and ADDH

ArticleYear
Controlled Antenatal Thyroid Screening II: Effect of Treating Maternal Suboptimal Thyroid Function on Child Behavior.
    The Journal of clinical endocrinology and metabolism, 2020, 03-01, Volume: 105, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Biomarkers; Case-Control Studies; Child; Child

2020
Clinical and endocrine features and long-term outcome of Graves' disease in early childhood.
    Journal of endocrinological investigation, 2007, Volume: 30, Issue:5

    Topics: Age of Onset; Antithyroid Agents; Attention Deficit Disorder with Hyperactivity; Carbimazole; Child;

2007

Other Studies

23 other studies available for thyroxine and ADDH

ArticleYear
Maternal Thyroid Anomalies and Attention-Deficit Hyperactivity Disorder in Progeny.
    American journal of epidemiology, 2022, 02-19, Volume: 191, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Female; Humans; Mothers; Pregnancy; Prenatal Exposure

2022
Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study.
    BMC medicine, 2022, 11-08, Volume: 20, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Cohort Studies; Female; Hum

2022
Maternal Iodine Status During Pregnancy Is Not Consistently Associated with Attention-Deficit Hyperactivity Disorder or Autistic Traits in Children.
    The Journal of nutrition, 2020, 06-01, Volume: 150, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Child, Preschool; Creatinin

2020
The association between thyroid function biomarkers and attention deficit hyperactivity disorder.
    Scientific reports, 2020, 10-26, Volume: 10, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cross-Sectional Studies; Female; H

2020
Thyroid and Cortisol hormones in Attention Deficit Hyperactivity Disorder: A case-control study.
    Asian journal of psychiatry, 2017, Volume: 28

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Biomarkers; Case-Control Studies; Child;

2017
Thyroid Hormone Status in Overweight Children with Attention Deficit/Hyperactivity Disorder.
    Hormone research in paediatrics, 2018, Volume: 89, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Cross-Sectional Studies; Female; Humans; Male;

2018
A Novel Homozygous Selenocysteine Insertion Sequence Binding Protein 2 (SECISBP2, SBP2) Gene Mutation in a Turkish Boy.
    Thyroid : official journal of the American Thyroid Association, 2018, Volume: 28, Issue:9

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Humans; Male; Muscle Weakness; Mutagenesis, In

2018
Maternal Prenatal Thyroid Function and Offspring ADHD: Findings From the ALSPAC Cohort.
    The Journal of nervous and mental disease, 2018, Volume: 206, Issue:11

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Iodide Pero

2018
Maternal Mild Thyroid Hormone Insufficiency in Early Pregnancy and Attention-Deficit/Hyperactivity Disorder Symptoms in Children.
    JAMA pediatrics, 2015, Volume: 169, Issue:9

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Female; Follow-Up Studies; Gestational

2015
Mild deficits in attentional control in patients with the IGSF1 deficiency syndrome.
    Clinical endocrinology, 2016, Volume: 84, Issue:6

    Topics: Adolescent; Adult; Aged; Attention; Attention Deficit Disorder with Hyperactivity; Case-Control Stud

2016
IGSF1 Deficiency: Lessons From an Extensive Case Series and Recommendations for Clinical Management.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Attention Deficit Disorder with Hyperactivity; Child; Ch

2016
Commentary: discordant measurements of serum triiodothyronine (T4), thyroxine (T3) and thyroid-stimulating hormone (TSH).
    Clinical chemistry, 2008, Volume: 54, Issue:7

    Topics: Antibodies, Heterophile; Attention Deficit Disorder with Hyperactivity; Female; Humans; Immunoassay;

2008
Impact of neonatal thyroid hormone insufficiency and medical morbidity on infant neurodevelopment and attention following preterm birth.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Child Development; Developmental Disabilities; Humans

2009
Severe affective and behavioral dysregulation in youth is associated with increased serum TSH.
    Journal of affective disorders, 2010, Volume: 121, Issue:1-2

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Anxiety Disorders; Attention Deficit Disord

2010
Co-existence of ADHD, autoimmune hypothyroidism and pituitary macroadenoma presenting in a behaviour clinic: a case report and brief review of the literature.
    Journal of pediatric endocrinology & metabolism : JPEM, 2011, Volume: 24, Issue:3-4

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Autoimmune Diseases; Community Mental Hea

2011
Thyroid function tests and neurocognitive functioning in children referred for attention deficit/hyperactivity disorder.
    Psychoneuroendocrinology, 2003, Volume: 28, Issue:3

    Topics: Adolescent; Affect; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Behavior; C

2003
TSH concentration within the normal range is associated with cognitive function and ADHD symptoms in healthy preschoolers.
    Clinical endocrinology, 2007, Volume: 66, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Child, Preschool; Cognition Disorders; Cross-Sectiona

2007
ADHD and thyroid abnormalities: a research note.
    Journal of child psychology and psychiatry, and allied disciplines, 1995, Volume: 36, Issue:5

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Diagnosis, Diffe

1995
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone.
    The New England journal of medicine, 1993, Apr-08, Volume: 328, Issue:14

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Drug Resistance; Female; Humans; Male;

1993
Thyroid hormone and attention in school-age children with congenital hypothyroidism.
    Journal of child psychology and psychiatry, and allied disciplines, 1996, Volume: 37, Issue:5

    Topics: Attention; Attention Deficit Disorder with Hyperactivity; Child; Congenital Hypothyroidism; Female;

1996
Evaluation of pituitary and peripheral tissue markers of thyroid hormone action in an Iranian family with resistance to thyroid hormone.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:6

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Ferritins; Humans; Iran; Male; Pedigree;

1996
ADHD/thyroid dysfunction.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1997, Volume: 36, Issue:12

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Male; Neurocogniti

1997
Newborn thyroxine levels and childhood ADHD.
    Clinical biochemistry, 2002, Volume: 35, Issue:2

    Topics: Age Factors; Attention Deficit Disorder with Hyperactivity; Biomarkers; Case-Control Studies; Child;

2002