Page last updated: 2024-11-06

thymidine and Keloid

thymidine has been researched along with Keloid in 3 studies

Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.

Research Excerpts

ExcerptRelevanceReference
" The cytotoxicity and bystander effects of Dm‑dNK combined with cytotoxic nucleoside analogs were both observed in Dm‑dNK+ keloid fibroblasts."1.48Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts. ( Gu, M; Jiang, H; Sun, Y; Zheng, X, 2018)
"A keloid is a pathological overgrowth of scar expanding beyond the boundaries of the initiating skin wound."1.29Increased proliferation in keloid fibroblasts wounded in vitro. ( Banes, AJ; Calderon, M; Lawrence, WT, 1996)
"When indomethacin was added with PMA the delayed peak appeared in normal fibroblasts."1.28Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters. Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered down-regulation of phorbol ester binding sites. ( Myles, ME; Russell, JD; Russell, SB; Smith, JC; Trupin, JS, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, Y1
Jiang, H1
Gu, M1
Zheng, X1
Calderon, M1
Lawrence, WT1
Banes, AJ1
Myles, ME1
Russell, JD1
Trupin, JS1
Smith, JC1
Russell, SB1

Other Studies

3 other studies available for thymidine and Keloid

ArticleYear
Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts.
    Molecular medicine reports, 2018, Volume: 18, Issue:2

    Topics: Adult; Animals; Apoptosis; Arabinonucleosides; Bromodeoxyuridine; Bystander Effect; Cell Proliferati

2018
Increased proliferation in keloid fibroblasts wounded in vitro.
    The Journal of surgical research, 1996, Volume: 61, Issue:2

    Topics: Autoradiography; Cell Count; Cell Division; Cells, Cultured; Fibroblasts; Humans; Keloid; Thymidine;

1996
Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters. Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered down-regulation of phorbol ester binding sites.
    The Journal of biological chemistry, 1992, May-05, Volume: 267, Issue:13

    Topics: Binding Sites; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Dinoprostone; DNA

1992