thymidine has been researched along with Keloid in 3 studies
Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
Excerpt | Relevance | Reference |
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" The cytotoxicity and bystander effects of Dm‑dNK combined with cytotoxic nucleoside analogs were both observed in Dm‑dNK+ keloid fibroblasts." | 1.48 | Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts. ( Gu, M; Jiang, H; Sun, Y; Zheng, X, 2018) |
"A keloid is a pathological overgrowth of scar expanding beyond the boundaries of the initiating skin wound." | 1.29 | Increased proliferation in keloid fibroblasts wounded in vitro. ( Banes, AJ; Calderon, M; Lawrence, WT, 1996) |
"When indomethacin was added with PMA the delayed peak appeared in normal fibroblasts." | 1.28 | Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters. Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered down-regulation of phorbol ester binding sites. ( Myles, ME; Russell, JD; Russell, SB; Smith, JC; Trupin, JS, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sun, Y | 1 |
Jiang, H | 1 |
Gu, M | 1 |
Zheng, X | 1 |
Calderon, M | 1 |
Lawrence, WT | 1 |
Banes, AJ | 1 |
Myles, ME | 1 |
Russell, JD | 1 |
Trupin, JS | 1 |
Smith, JC | 1 |
Russell, SB | 1 |
3 other studies available for thymidine and Keloid
Article | Year |
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Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts.
Topics: Adult; Animals; Apoptosis; Arabinonucleosides; Bromodeoxyuridine; Bystander Effect; Cell Proliferati | 2018 |
Increased proliferation in keloid fibroblasts wounded in vitro.
Topics: Autoradiography; Cell Count; Cell Division; Cells, Cultured; Fibroblasts; Humans; Keloid; Thymidine; | 1996 |
Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters. Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered down-regulation of phorbol ester binding sites.
Topics: Binding Sites; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Dinoprostone; DNA | 1992 |