thalidomide has been researched along with HIV in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
Excerpt | Relevance | Reference |
---|---|---|
"Thalidomide (400 mg) was orally administered to 6 men, and their blood was stimulated ex vivo with LPS, staphylococcal or mycobacterial antigens, or antibody to CD3 or CD28 cells." | 1.31 | Thalidomide suppresses Up-regulation of human immunodeficiency virus coreceptors CXCR4 and CCR5 on CD4+ T cells in humans. ( Juffermans, NP; Olszyna, DP; Speelman, P; van Der Poll, T; van Deventer, SJ; Verbon, A, 2000) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Liu, P | 1 |
Pei, N | 1 |
Liu, X | 1 |
Huang, W | 1 |
Lu, S | 1 |
Agrawal, S | 1 |
Deshpande, A | 1 |
Wolday, D | 1 |
Akuffo, H | 1 |
Demissie, A | 1 |
Britton, S | 1 |
Juffermans, NP | 1 |
Verbon, A | 1 |
Olszyna, DP | 1 |
van Deventer, SJ | 1 |
Speelman, P | 1 |
van Der Poll, T | 1 |
4 other studies available for thalidomide and HIV
Article | Year |
---|---|
Thalidomide in the treatment of human immunodeficiency virus-negative tuberculous meningitis: A case report.
Topics: Adrenal Cortex Hormones; Adult; Antitubercular Agents; Asian People; Brain; Drug Therapy, Combinatio | 2020 |
A unique presentation of multiple myeloma in an HIV patient.
Topics: Aged; HIV; HIV Infections; HIV Seropositivity; Humans; Male; Multiple Myeloma; Radiography; Thalidom | 2013 |
Role of Leishmania donovani and its lipophosphoglycan in CD4+ T-cell activation-induced human immunodeficiency virus replication.
Topics: Adult; Animals; Antigens, Protozoan; Apoptosis; CD4-Positive T-Lymphocytes; Cytokines; Glycosphingol | 1999 |
Thalidomide suppresses Up-regulation of human immunodeficiency virus coreceptors CXCR4 and CCR5 on CD4+ T cells in humans.
Topics: Adult; CD4-Positive T-Lymphocytes; Cells, Cultured; HIV; Humans; Kinetics; Lipopolysaccharides; Male | 2000 |