thalidomide has been researched along with Goiter in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Goiter is relatively common in infants whose mothers were treated with propylthiouracil and other antithyroid drugs, yet they usually show normal thyroid function." | 1.25 | Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs. ( Shirkey, HC, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shirkey, HC | 1 |
| Lenz, W | 1 |
| Wolf, HG | 1 |
3 other studies available for thalidomide and Goiter
| Article | Year |
|---|---|
Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Antithyroid Agents; Contraceptives, Oral; Diethy | 1972 |
Phenocopy.
Topics: Abnormalities, Multiple; Anemia, Aplastic; Arm; Congenital Hypothyroidism; Deafness; Female; Feminiz | 1970 |
[Prenatal and neonatal drug-induced lesions].
Topics: Abnormalities, Drug-Induced; Adult; Androgens; Drug-Related Side Effects and Adverse Reactions; Eryt | 1968 |