Page last updated: 2024-11-05

thalidomide and Goiter

thalidomide has been researched along with Goiter in 3 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).

Research Excerpts

ExcerptRelevanceReference
"Goiter is relatively common in infants whose mothers were treated with propylthiouracil and other antithyroid drugs, yet they usually show normal thyroid function."1.25Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs. ( Shirkey, HC, 1972)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shirkey, HC1
Lenz, W1
Wolf, HG1

Other Studies

3 other studies available for thalidomide and Goiter

ArticleYear
Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs.
    Advances in experimental medicine and biology, 1972, Volume: 27

    Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Antithyroid Agents; Contraceptives, Oral; Diethy

1972
Phenocopy.
    Humangenetik, 1970, Volume: 9, Issue:3

    Topics: Abnormalities, Multiple; Anemia, Aplastic; Arm; Congenital Hypothyroidism; Deafness; Female; Feminiz

1970
[Prenatal and neonatal drug-induced lesions].
    Wiener klinische Wochenschrift, 1968, Jun-21, Volume: 80, Issue:25

    Topics: Abnormalities, Drug-Induced; Adult; Androgens; Drug-Related Side Effects and Adverse Reactions; Eryt

1968