suramin and Leprosy
suramin has been researched along with Leprosy in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| WONG, PC | 2 |
| MA, L | 2 |
| REES, RJ | 1 |
| CHEN, M | 1 |
| TIE, GC | 1 |
Other Studies
3 other studies available for suramin and Leprosy
| Article | Year |
|---|---|
Effect of suramin on serum protein in Mycobacterium lepraemurium-infected mice.
Topics: Animals; Blood Proteins; Leprosy; Mice; Mycobacterium lepraemurium; Suramin | 1963 |
LIMITED MULTIPLICATION OF ACID-FAST BACILLI IN THE FOOT-PADS OF MICE INOCULATED WITH MYCOBACTERIUM LEPRAE.
Topics: Animals; Bacteria; Leprosy; Mice; Mycobacterium leprae; Research; Skin; Suramin | 1964 |
LACTATE DEHYDROGENASE ACTIVITY IN MOUSE LIVER INFECTED WITH MYCOBACTERIUM LEPRAEMURIUM.
Topics: Animals; Clinical Enzyme Tests; L-Lactate Dehydrogenase; Leprosy; Liver; Mice; Mycobacterium lepraem | 1965 |