Page last updated: 2024-11-04

suramin and Heart Failure

suramin has been researched along with Heart Failure in 3 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Blanco-Rivero, J1
Couto, GK1
Paula, SM1
Fontes, MT1
Rossoni, LV1
Wu, Y1
Sun, X1
Ishida, J1
Springer, J1

Other Studies

3 other studies available for suramin and Heart Failure

ArticleYear
Enhanced sympathetic neurotransduction in the superior mesenteric artery in a rat model of heart failure: role of noradrenaline and ATP.
    American journal of physiology. Heart and circulatory physiology, 2021, 02-01, Volume: 320, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Desipra

2021
Suramin against myostatin signaling may be considered to intervene in female patients with advanced heart failure.
    International journal of cardiology, 2017, 11-15, Volume: 247

    Topics: Female; Heart Failure; Humans; Myostatin; Signal Transduction; Suramin

2017
Reply to letter to the editor "suramin against myostatin signaling may be considered to intervene in female patients with advanced heart failure".
    International journal of cardiology, 2017, 11-15, Volume: 247

    Topics: Female; Heart Failure; Humans; Myocardium; Myostatin; Signal Transduction; Suramin

2017