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suprofen and Pain

suprofen has been researched along with Pain in 25 studies

Suprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
suprofen : An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"The role of spontaneous reporting in detecting the suprofen-associated flank pain syndrome was examined, including the specific effect of the "Dear Doctor" letter in accelerating the information-gathering process once the initial signal was generated."9.06The importance of adverse reaction reporting by physicians. Suprofen and the flank pain syndrome. ( Bosco, L; Faich, GA; Rossi, AC; Tanner, A; Temple, R, 1988)
"In a placebo-controlled double-blind trial analgesic effectiveness and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) 300 mg suppositories were evaluated for 45 informed patients suffering from chronic pain due to osteoarthritis; the subjects were treated rectally, t."9.06Double-blind placebo-controlled study of the efficacy and tolerability of suprofen suppositories in patients with osteoarthritic pain. ( Menicanti, V; Michos, N; Nebiolo, M; Sarchi, C; Viara, M, 1986)
"43 patients with osteoarthritis of the knee and/or hip(s) were treated with suprofen 800 mg/day or ibuprofen 1,600 mg/day for 14 days."9.05Comparison of suprofen and ibuprofen in the treatment of pain secondary to osteoarthritis. ( Schuermans, Y, 1983)
"The effectiveness and safety of suprofen 200 mg, aspirin 650 mg, and placebo in the treatment of moderate to severe pain were compared in a 72-hour multiple-dose, double-blind, parallel, randomized study in 75 adults suffering from musculoskeletal pain."9.05Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain. ( Silberman, HM, 1983)
"In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0."9.05Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985)
"Suprofen, a nonsteroidal anti-inflammatory drug, has been associated with the onset of acute flank pain, hematuria, and transient renal dysfunction after the ingestion of one or two doses, particularly in young males."7.67Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain. ( Abraham, PA; Halstenson, CE; Keane, WF; Matzke, GR; Opsahl, JA, 1988)
"Analgesic effect and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) drops were tested in an open study including 51 informed outpatients with moderate to severe postoperative and posttraumatic pain."7.67Open clinical study with suprofen drops in the treatment of postoperative and posttraumatic pain. ( Michos, N; Probst, G, 1986)
"This 4-week, open design study was conducted to evaluate the efficacy and safety of suprofen (200-1,200 mg/day) in the treatment of elderly patients with pain of diverse origin, all of whom suffered from secondary disorders."7.66Clinical evaluation of suprofen in the treatment of elderly patients with pain of diverse etiology. ( de Beer, JM; Denis, FR, 1983)
" Long-term administration of suprofen was at least as well tolerated as that of propoxyphene."6.65Long-term comparison of suprofen and propoxyphene in patients with osteoarthritis. ( Brobyn, RD; Salzman, RT, 1983)
"The role of spontaneous reporting in detecting the suprofen-associated flank pain syndrome was examined, including the specific effect of the "Dear Doctor" letter in accelerating the information-gathering process once the initial signal was generated."5.06The importance of adverse reaction reporting by physicians. Suprofen and the flank pain syndrome. ( Bosco, L; Faich, GA; Rossi, AC; Tanner, A; Temple, R, 1988)
"The analgesic effect and the tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) syrup 200 mg and metamizole syrup 500 mg were compared in a randomized single-blind study including hospitalized patients with severe to moderate chronic pain."5.06Controlled single-blind clinical study of suprofen syrup versus metamizole syrup. ( Michos, N; von Szeged, AV, 1986)
"In a placebo-controlled double-blind trial analgesic effectiveness and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) 300 mg suppositories were evaluated for 45 informed patients suffering from chronic pain due to osteoarthritis; the subjects were treated rectally, t."5.06Double-blind placebo-controlled study of the efficacy and tolerability of suprofen suppositories in patients with osteoarthritic pain. ( Menicanti, V; Michos, N; Nebiolo, M; Sarchi, C; Viara, M, 1986)
"43 patients with osteoarthritis of the knee and/or hip(s) were treated with suprofen 800 mg/day or ibuprofen 1,600 mg/day for 14 days."5.05Comparison of suprofen and ibuprofen in the treatment of pain secondary to osteoarthritis. ( Schuermans, Y, 1983)
"The effectiveness and safety of suprofen 200 mg, aspirin 650 mg, and placebo in the treatment of moderate to severe pain were compared in a 72-hour multiple-dose, double-blind, parallel, randomized study in 75 adults suffering from musculoskeletal pain."5.05Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain. ( Silberman, HM, 1983)
"Suprofen, a new oral peripherally acting analgesic agent, has been shown to be effective in the relief of acute and chronic pain."5.05Suprofen. An overview of long-term safety. ( Gardner, MC; Milak, DM; Raina, M; Smith, KE; Yeadon, A, 1983)
"In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0."5.05Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985)
"Suprofen (sutoprofen) is a non-steroidal anti-inflammatory analgesic, closely related structurally to drugs such as ibuprofen, ketoprofen and naproxen."3.75Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy. ( Heel, RC; Todd, PA, 1985)
"Suprofen, a nonsteroidal anti-inflammatory drug, has been associated with the onset of acute flank pain, hematuria, and transient renal dysfunction after the ingestion of one or two doses, particularly in young males."3.67Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain. ( Abraham, PA; Halstenson, CE; Keane, WF; Matzke, GR; Opsahl, JA, 1988)
"Analgesic effect and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) drops were tested in an open study including 51 informed outpatients with moderate to severe postoperative and posttraumatic pain."3.67Open clinical study with suprofen drops in the treatment of postoperative and posttraumatic pain. ( Michos, N; Probst, G, 1986)
"We describe a unique clinical syndrome of flank pain and acute renal failure that is associated with suprofen, a nonsteroidal anti-inflammatory drug that has recently been made available in the United States."3.67Suprofen-related nephrotoxicity. A distinct clinical syndrome. ( Hart, D; Lifschitz, MD; Ward, M, 1987)
"This 4-week, open design study was conducted to evaluate the efficacy and safety of suprofen (200-1,200 mg/day) in the treatment of elderly patients with pain of diverse origin, all of whom suffered from secondary disorders."3.66Clinical evaluation of suprofen in the treatment of elderly patients with pain of diverse etiology. ( de Beer, JM; Denis, FR, 1983)
"In a randomized double-dummy study a new dosage form of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol), i."2.66Double-dummy comparison of suprofen and indometacin sustained release formulations. ( Höbel, W; Michos, N; Schenker, H, 1986)
" Long-term administration of suprofen was at least as well tolerated as that of propoxyphene."2.65Long-term comparison of suprofen and propoxyphene in patients with osteoarthritis. ( Brobyn, RD; Salzman, RT, 1983)
"Suprofen is a potent, peripherally-acting, non-narcotic analgesic agent."2.37Suprofen: the pharmacology and clinical efficacy of a new non-narcotic peripheral analgesic. ( Capetola, RJ; McGuire, JL; Rosenthale, ME; Tolman, EL, 1984)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199025 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vargha von Szeged, A1
Michos, N6
Schuermans, Y1
Salzman, RT1
Brobyn, RD1
Silberman, HM1
Yeadon, A1
Raina, M1
Gardner, MC1
Milak, DM1
Smith, KE1
Tolman, EL1
Rosenthale, ME1
Capetola, RJ1
McGuire, JL1
Denis, FR1
de Beer, JM1
Colpaert, FC1
De Witte, P1
Maroli, AN1
Awouters, F1
Niemegeers, CJ1
Janssen, PA1
Strom, BL1
West, SL1
Sim, E1
Carson, JL1
Rossi, AC1
Bosco, L1
Faich, GA1
Tanner, A1
Temple, R1
Abraham, PA1
Halstenson, CE1
Opsahl, JA1
Matzke, GR1
Keane, WF1
von Szeged, AV1
Viara, M1
Menicanti, V1
Nebiolo, M1
Sarchi, C1
Wolfe, SM1
Talmud, J1
Davey, J1
Schenker, H1
Höbel, W1
Probst, G1
Hart, D1
Ward, M1
Lifschitz, MD1
Henann, NE1
Morales, JR1
Amantea, B1
Savoia, G1
Belfiore, F1
Esposito, C1
Cuocolo, R1
Weippl, G1
Stocker, H1
Todd, PA1
Heel, RC1

Reviews

2 reviews available for suprofen and Pain

ArticleYear
Suprofen: the pharmacology and clinical efficacy of a new non-narcotic peripheral analgesic.
    Clinics in rheumatic diseases, 1984, Volume: 10, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Drug Evaluation, Preclinical; Fem

1984
Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy.
    Drugs, 1985, Volume: 30, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; D

1985

Trials

12 trials available for suprofen and Pain

ArticleYear
[Experience with suprofen for acute and chronic pain in neurologic practice].
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:9

    Topics: Acute Disease; Adult; Aspirin; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug

1983
Comparison of suprofen and ibuprofen in the treatment of pain secondary to osteoarthritis.
    Pharmacology, 1983, Volume: 27 Suppl 1

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; M

1983
Long-term comparison of suprofen and propoxyphene in patients with osteoarthritis.
    Pharmacology, 1983, Volume: 27 Suppl 1

    Topics: Aged; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Drug Interactions; Female;

1983
Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain.
    Pharmacology, 1983, Volume: 27 Suppl 1

    Topics: Adolescent; Adult; Aged; Aspirin; Bone Diseases; Clinical Trials as Topic; Dose-Response Relationshi

1983
Suprofen. An overview of long-term safety.
    Pharmacology, 1983, Volume: 27 Suppl 1

    Topics: Adult; Aged; Aspirin; Blood Chemical Analysis; Clinical Trials as Topic; Dextropropoxyphene; Double-

1983
The importance of adverse reaction reporting by physicians. Suprofen and the flank pain syndrome.
    JAMA, 1988, Feb-26, Volume: 259, Issue:8

    Topics: Acute Kidney Injury; Clinical Trials as Topic; Data Collection; Drug Industry; Europe; Humans; Pain;

1988
Suprofen.
    The Medical letter on drugs and therapeutics, 1986, May-23, Volume: 28, Issue:714

    Topics: Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Pain; Phenylpropionates; Suprof

1986
Controlled single-blind clinical study of suprofen syrup versus metamizole syrup.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:7

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Methimazole; Middle Ag

1986
Double-blind placebo-controlled study of the efficacy and tolerability of suprofen suppositories in patients with osteoarthritic pain.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:7

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Osteoarthritis; Pain; Ph

1986
Double-dummy comparison of suprofen and indometacin sustained release formulations.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:6

    Topics: Aged; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle A

1986
Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child, Preschool; Drug Combinations; Humans; In

1985
Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy.
    Drugs, 1985, Volume: 30, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; D

1985

Other Studies

12 other studies available for suprofen and Pain

ArticleYear
Clinical evaluation of suprofen in the treatment of elderly patients with pain of diverse etiology.
    Pharmacology, 1983, Volume: 27 Suppl 1

    Topics: Aged; Female; Humans; Male; Middle Aged; Pain; Phenylpropionates; Suprofen; Time Factors

1983
Self-administration of the analgesic suprofen in arthritic rats: evidence of Mycobacterium butyricum-induced arthritis as an experimental model of chronic pain.
    Life sciences, 1980, Sep-15, Volume: 27, Issue:11

    Topics: Animals; Arthritis; Arthritis, Experimental; Chronic Disease; Conditioning, Psychological; Disease M

1980
The epidemiology of the acute flank pain syndrome from suprofen.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:6

    Topics: Acute Kidney Injury; Adult; Asthma; Case-Control Studies; Exercise; Female; Humans; Incidence; Kidne

1989
Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain.
    American journal of nephrology, 1988, Volume: 8, Issue:2

    Topics: Acute Disease; Adult; Humans; Kidney Concentrating Ability; Kidney Diseases; Male; Pain; Phenylpropi

1988
Suprofen-induced transient flank pain and renal failure.
    The New England journal of medicine, 1987, Apr-16, Volume: 316, Issue:16

    Topics: Acute Kidney Injury; Adult; Hip; Humans; Male; Pain; Phenylpropionates; Suprofen; Uricosuric Agents

1987
Suprofen, flank pain and renal involvement: a case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1987, Aug-01, Volume: 72, Issue:3

    Topics: Abdomen; Adult; Humans; Kidney; Male; Pain; Phenylpropionates; Suprofen

1987
Adverse reaction reported with suprofen.
    FDA drug bulletin, 1986, Volume: 16, Issue:1

    Topics: Creatinine; Humans; Pain; Phenylpropionates; Suprofen; United States; United States Food and Drug Ad

1986
Open clinical study with suprofen drops in the treatment of postoperative and posttraumatic pain.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:7

    Topics: Adult; Female; Humans; Male; Middle Aged; Pain; Pain, Postoperative; Phenylpropionates; Suprofen; Wo

1986
Suprofen-related nephrotoxicity. A distinct clinical syndrome.
    Annals of internal medicine, 1987, Volume: 106, Issue:2

    Topics: Abdomen; Acute Kidney Injury; Adolescent; Adult; Female; Humans; Male; Middle Aged; Pain; Phenylprop

1987
Suprofen-induced acute renal failure revisited.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:1 Pt 1

    Topics: Acute Kidney Injury; Adult; Humans; Male; Pain; Phenylpropionates; Suprofen

1987
Suprofen labeling revised.
    FDA drug bulletin, 1986, Volume: 16, Issue:2

    Topics: Back; Drug Labeling; Humans; Kidney Diseases; Pain; Phenylpropionates; Suprofen

1986
[Somatosensory evoked potentials in pain studies].
    Minerva anestesiologica, 1985, Volume: 51, Issue:5

    Topics: Adult; Buprenorphine; Evoked Potentials, Somatosensory; Humans; Morphine; Naloxone; Pain; Recruitmen

1985