sulpiride has been researched along with Drooling in 9 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The beneficial effect of sulpiride augmentation of clozapine therapy for treatment-resistant schizophrenia patients is enhanced by its antisalivatory effect on clozapine-induced hypersalivation (CIH)." | 9.12 | Amisulpride treatment of clozapine-induced hypersalivation in schizophrenia patients: a randomized, double-blind, placebo-controlled cross-over study. ( Kreinin, A; Novitski, D; Weizman, A, 2006) |
| "Amisulpride is suggested for treatment of clozapine-induced sialorrhea." | 7.78 | Atypical antipsychotics--effects of amisulpride on salivary secretion and on clozapine-induced sialorrhea. ( Ekström, J; Godoy, T; Riva, A, 2012) |
| "Clozapine induced sialorrhea is a common and troublesome adverse effect leading to poor treatment compliance." | 7.77 | Amisulpride improved debilitating clozapine-induced sialorrhea. ( Gandotra, S; Praharaj, SK; Ray, P, 2011) |
| "The study was designed as a 6-week, two-center, fixed-dose, comparison study of 400 mg/day of amisulpride versus 300 mg/day of moclobemide as an adjunctive treatment in 53 schizophrenia and schizoaffective disorder patients (diagnosed according to DSM-IV) suffering from CIS." | 5.15 | Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation. ( Bergman, J; Kreinin, A; Lerner, V; Libov, I; Miodownik, C; Shestakova, D; Sokolik, S, 2011) |
| "The beneficial effect of sulpiride augmentation of clozapine therapy for treatment-resistant schizophrenia patients is enhanced by its antisalivatory effect on clozapine-induced hypersalivation (CIH)." | 5.12 | Amisulpride treatment of clozapine-induced hypersalivation in schizophrenia patients: a randomized, double-blind, placebo-controlled cross-over study. ( Kreinin, A; Novitski, D; Weizman, A, 2006) |
| "Amisulpride is suggested for treatment of clozapine-induced sialorrhea." | 3.78 | Atypical antipsychotics--effects of amisulpride on salivary secretion and on clozapine-induced sialorrhea. ( Ekström, J; Godoy, T; Riva, A, 2012) |
| "Clozapine induced sialorrhea is a common and troublesome adverse effect leading to poor treatment compliance." | 3.77 | Amisulpride improved debilitating clozapine-induced sialorrhea. ( Gandotra, S; Praharaj, SK; Ray, P, 2011) |
| "The side effects, especially hypersalivation, disappeared almost entirely, which in turn led to good compliance." | 1.33 | Reduction of side effects by combining clozapine with amisulpride: case report and short review of clozapine-induced hypersalivation-a case report. ( Croissant, B; Hermann, D; Olbrich, R, 2005) |
| "Hypersalivation is a common, troublesome side effect of clozapine treatment." | 1.33 | Sulpiride addition for the treatment of clozapine-induced hypersalivation: preliminary study. ( Epshtein, S; Kreinin, A; Sheinkman, A; Tell, E, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Prljača, E | 1 |
| Bećirović, E | 1 |
| Hasanović, M | 1 |
| Pajević, I | 1 |
| Brigić, A | 1 |
| Praharaj, SK | 2 |
| Sarkar, S | 1 |
| Sinha, VK | 1 |
| Ray, P | 1 |
| Gandotra, S | 1 |
| Aggarwal, A | 1 |
| Sharma, DD | 1 |
| Kreinin, A | 3 |
| Miodownik, C | 1 |
| Sokolik, S | 1 |
| Shestakova, D | 1 |
| Libov, I | 1 |
| Bergman, J | 1 |
| Lerner, V | 1 |
| Godoy, T | 1 |
| Riva, A | 1 |
| Ekström, J | 1 |
| Croissant, B | 1 |
| Hermann, D | 1 |
| Olbrich, R | 1 |
| Epshtein, S | 1 |
| Sheinkman, A | 1 |
| Tell, E | 1 |
| Novitski, D | 1 |
| Weizman, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Benzamide Derivates (Amisulpride, Moclobemide and Tiapride) as Treatment of Clozapine-induced Hypersalivation: Pilot Double Phase Study: Open and Double-blind[NCT00534573] | Phase 3 | 54 participants (Actual) | Interventional | 2008-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for sulpiride and Drooling
| Article | Year |
|---|---|
Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation.
Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Clozapine; Cross-Over Studies; Female; Humans; Male; | 2011 |
Amisulpride treatment of clozapine-induced hypersalivation in schizophrenia patients: a randomized, double-blind, placebo-controlled cross-over study.
Topics: Amisulpride; Antipsychotic Agents; Clozapine; Cross-Over Studies; Double-Blind Method; Female; Human | 2006 |
7 other studies available for sulpiride and Drooling
| Article | Year |
|---|---|
Clozapine-Induced Hypersalivation Treated with Sulpiride - Is It a Solution?
Topics: Antipsychotic Agents; Clozapine; Humans; Schizophrenia; Sialorrhea; Sulpiride | 2021 |
Amisulpride treatment for clozapine-induced sialorrhea.
Topics: Adult; Amisulpride; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Anta | 2009 |
Amisulpride improved debilitating clozapine-induced sialorrhea.
Topics: Antipsychotic Agents; Clozapine; Dopamine Antagonists; Humans; Male; Middle Aged; Randomized Control | 2011 |
Amisulpride for clozapine induced sialorrhea.
Topics: Adult; Amisulpride; Antipsychotic Agents; Clozapine; Female; Humans; Sialorrhea; Sulpiride | 2009 |
Atypical antipsychotics--effects of amisulpride on salivary secretion and on clozapine-induced sialorrhea.
Topics: Amisulpride; Amylases; Animals; Antipsychotic Agents; Autonomic Agents; Bethanechol; Clozapine; Dene | 2012 |
Reduction of side effects by combining clozapine with amisulpride: case report and short review of clozapine-induced hypersalivation-a case report.
Topics: Adult; Amisulpride; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Male; Schizo | 2005 |
Sulpiride addition for the treatment of clozapine-induced hypersalivation: preliminary study.
Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Clozapine; Female; Follow-Up | 2005 |