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sulfamethoxazole and Granulomatosis with Polyangiitis

sulfamethoxazole has been researched along with Granulomatosis with Polyangiitis in 28 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Granulomatosis with Polyangiitis: A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN.

Research Excerpts

ExcerptRelevanceReference
"If the vasculitis is secondary to an underlying disease, such as lymphoma, therapy should be directed at the primary disease."2.37Pulmonary vasculitis. ( Fauci, AS; Leavitt, RY, 1986)
"Wegener's granulomatosis was confirmed by biopsy."1.30[Isolated laryngeal involvement as the first manifestation of Wegener's disease. A case report]. ( Grijalba Uche, M; López Cousillas, A; Medina Sola, JJ; Saiz Calleja, MA, 1997)
"A 50 year old man, affected by a Wegener's granulomatosis limited to lung, is presented."1.28[Trimethoprim-sulfamethoxazole++ in the treatment of a case of localized Wegener's granulomatosis]. ( Callol Sánchez, L; Cuevas Ibáñez, A; Gómez de Terreros, FJ; Moreno Muro, M; Villegas Fernández, FR, 1991)
"We report a patient with Wegener's granulomatosis who was initially stabilized, but later relapsed with multiorgan involvement while taking high oral doses of cyclophosphamide (3."1.28Wegener's granulomatosis: treatment failure on conventional therapy. ( Lindström, FD; Locht, H, 1989)
"Wegener's granulomatosis has traditionally been treated with steroids and cyclophosphamide."1.27Wegener's granulomatosis treated with sulfamethoxazole-trimethoprim. Report of a case. ( Lawson, W; Spiera, H; Weinrauch, H, 1988)
"Because patients with Wegener granulomatosis sometimes respond to trimethoprim-sulfamethoxazole, this therapy deserves careful study and implies that Wegener granulomatosis is an as yet unidentified infection."1.27Wegener granulomatosis and trimethoprim-sulfamethoxazole. Complete remission after a twenty-year course. ( King, JW; Todd, JR; West, BC, 1987)
"Twelve patients with Wegener's granulomatosis were treated with antimicrobial agents, chiefly trimethoprim-sulfamethoxazole."1.27Wegener's granulomatosis: observations on treatment with antimicrobial agents. ( DeRemee, RA; McDonald, TJ; Weiland, LH, 1985)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199018 (64.29)18.7374
1990's9 (32.14)18.2507
2000's1 (3.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Groot, K1
Reinhold-Keller, E1
Tatsis, E1
Paulsen, J1
Heller, M1
Nölle, B1
Gross, WL3
Grijalba Uche, M1
López Cousillas, A1
Medina Sola, JJ1
Saiz Calleja, MA1
Jaffe, IA1
Jolly, M1
Molta, C1
Hoffman, G1
Kondo, H1
Villegas Fernández, FR1
Callol Sánchez, L1
Moreno Muro, M1
Cuevas Ibáñez, A1
Gómez de Terreros, FJ1
Ogawa, M1
Azemoto, R1
Makino, Y1
Mori, Y1
Ueda, S1
Wakashin, M1
Ohto, M1
Colby, TV1
Tazelaar, HD1
Specks, U1
DeRemee, RA3
Rasmussen, N1
Petersen, J1
Remvig, L1
Andersen, V1
Hoen, B1
Aymard, B1
Gerard, A1
Brunet, A1
Mertes, PM1
May, T1
Canton, P1
Dureux, JB1
Locht, H1
Lindström, FD1
Steppat, D2
Boudes, P2
Fukuda, K1
Yuasa, K2
Uchizono, A1
Matsuyama, H1
Shimada, K2
Ohyama, M1
West, BC2
Todd, JR2
King, JC1
Bowden, FJ1
Griffiths, H1
Leavitt, RY2
Fauci, AS2
Tokitsu, M1
Goto, H1
Kato, H1
Hoffman, GS1
Spiera, H1
Lawson, W1
Weinrauch, H1
Israel, HL1
King, JW1
Axelson, JA1
Clark, RH1
Ancerewicz, S1
McDonald, TJ1
Weiland, LH1
Skevas, A1
Schmidt-Bäumler, U1

Reviews

2 reviews available for sulfamethoxazole and Granulomatosis with Polyangiitis

ArticleYear
Wegener's granulomatosis and ANCA syndromes.
    Neurologic clinics, 1997, Volume: 15, Issue:4

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Anti-Infective Agents; Antibodies, Antineutrophil Cytopl

1997
Pulmonary vasculitis.
    The American review of respiratory disease, 1986, Volume: 134, Issue:1

    Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Chlorambucil; Connective Tissue Diseases; Cy

1986

Trials

1 trial available for sulfamethoxazole and Granulomatosis with Polyangiitis

ArticleYear
Treatment of Wegener's granulomatosis with trimethoprim-sulfamethoxazole.
    APMIS. Supplementum, 1990, Volume: 19

    Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Granulomatosis with Polyangiitis; Humans; Sulfamet

1990

Other Studies

25 other studies available for sulfamethoxazole and Granulomatosis with Polyangiitis

ArticleYear
Therapy for the maintenance of remission in sixty-five patients with generalized Wegener's granulomatosis. Methotrexate versus trimethoprim/sulfamethoxazole.
    Arthritis and rheumatism, 1996, Volume: 39, Issue:12

    Topics: Adolescent; Adult; Aged; Child; Drug Therapy, Combination; Female; Granulomatosis with Polyangiitis;

1996
[Isolated laryngeal involvement as the first manifestation of Wegener's disease. A case report].
    Acta otorrinolaringologica espanola, 1997, Volume: 48, Issue:3

    Topics: Aged; Anti-Infective Agents; Drug Combinations; Drug Therapy, Combination; Female; Granulomatosis wi

1997
Wegener's granulomatosis: pitfalls in the management of pulmonary disease: A case of Wegener's granulomatosis with a hilar mass.
    The Journal of rheumatology, 2000, Volume: 27, Issue:10

    Topics: Adult; Cyclophosphamide; Drug Therapy, Combination; Ethambutol; Granulomatosis with Polyangiitis; Hu

2000
[Progress on diagnosis of Wegener's granulomatosis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Nov-10, Volume: 80, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Cyclophosphami

1991
[Trimethoprim-sulfamethoxazole++ in the treatment of a case of localized Wegener's granulomatosis].
    Revista clinica espanola, 1991, Volume: 188, Issue:7

    Topics: Drug Therapy, Combination; Granulomatosis with Polyangiitis; Humans; Male; Middle Aged; Sulfamethoxa

1991
Pneumothorax in a patient with Wegener's granulomatosis during treatment with immunosuppressive agents.
    Journal of internal medicine, 1991, Volume: 229, Issue:2

    Topics: Adolescent; Cyclophosphamide; Drug Therapy, Combination; Female; Glucocorticoids; Granulomatosis wit

1991
Nasal biopsy in Wegener's granulomatosis.
    Human pathology, 1991, Volume: 22, Issue:2

    Topics: Antibodies; Biopsy; Cytoplasm; Granulomatosis with Polyangiitis; Humans; Nasal Mucosa; Necrosis; Neu

1991
Sulfamethoxazole-trimethoprim (SMZ-TMP) as an effective therapy for Wegener's granulomatosis (WG)--three more cases.
    APMIS. Supplementum, 1990, Volume: 19

    Topics: Adult; Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Biomarkers; Dr

1990
Wegener's granulomatosis: treatment failure on conventional therapy.
    The Journal of rheumatology, 1989, Volume: 16, Issue:4

    Topics: Adult; Cyclophosphamide; Granulomatosis with Polyangiitis; Humans; Infusions, Intravenous; Male; Pla

1989
Comment on the article by DeRemee.
    Arthritis and rheumatism, 1989, Volume: 32, Issue:8

    Topics: Clinical Protocols; Granulomatosis with Polyangiitis; Humans; Sulfamethoxazole; Trimethaphan

1989
Wegener's granulomatosis and trimethoprim/sulfamethoxazole treatment.
    Arthritis and rheumatism, 1989, Volume: 32, Issue:8

    Topics: Clinical Protocols; Granulomatosis with Polyangiitis; Humans; Sulfamethoxazole; Trimethaphan

1989
Three cases of Wegener's granulomatosis treated with an antimicrobial agent.
    Archives of otolaryngology--head & neck surgery, 1989, Volume: 115, Issue:4

    Topics: Adult; Anti-Infective Agents; Azathioprine; Drug Combinations; Drug Therapy, Combination; Female; Gr

1989
The treatment of Wegener's granulomatosis with sulfamethoxazole and trimethoprim.
    Archives of internal medicine, 1989, Volume: 149, Issue:6

    Topics: Drug Combinations; Female; Granulomatosis with Polyangiitis; Humans; Sulfamethoxazole; Trimethoprim;

1989
Wegener's granulomatosis.
    Archives of internal medicine, 1989, Volume: 149, Issue:7

    Topics: Drug Combinations; Granulomatosis with Polyangiitis; Humans; Sulfamethoxazole; Trimethoprim; Trimeth

1989
Stage-adapted treatment of Wegener's granulomatosis. First results of a prospective study.
    Klinische Wochenschrift, 1989, Jul-03, Volume: 67, Issue:13

    Topics: Anti-Infective Agents; Cyclophosphamide; Drug Administration Schedule; Drug Combinations; Drug Thera

1989
Co-trimoxazole in the treatment of Wegener's granulomatosis.
    The Medical journal of Australia, 1989, Sep-04, Volume: 151, Issue:5

    Topics: Aged; Anti-Infective Agents; Drug Combinations; Female; Granulomatosis with Polyangiitis; Humans; Su

1989
The treatment of Wegener's granulomatosis with trimethoprim/sulfamethoxazole: illusion or vision?
    Arthritis and rheumatism, 1988, Volume: 31, Issue:8

    Topics: Anti-Infective Agents; Cyclophosphamide; Drug Combinations; Germany; Granulomatosis with Polyangiiti

1988
Wegener's granulomatosis: diagnosis by transbronchial lung biopsy, evaluation by gallium scintigraphy and treatment with sulfamethoxazole/trimethoprim.
    The American journal of medicine, 1988, Volume: 84, Issue:2

    Topics: Anti-Infective Agents; Drug Combinations; Granulomatosis with Polyangiitis; Humans; Male; Middle Age

1988
The role of trimethoprim/sulfamethoxazole in the treatment of Wegener's granulomatosis.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:8

    Topics: Anti-Infective Agents; Drug Combinations; Granulomatosis with Polyangiitis; Humans; Research Design;

1988
Wegener's granulomatosis treated with sulfamethoxazole-trimethoprim. Report of a case.
    Archives of internal medicine, 1988, Volume: 148, Issue:9

    Topics: Anti-Infective Agents; Drug Administration Schedule; Drug Combinations; Granulomatosis with Polyangi

1988
Sulfamethoxazole-trimethoprim therapy for Wegener's granulomatosis.
    Archives of internal medicine, 1988, Volume: 148, Issue:10

    Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Granulom

1988
Wegener granulomatosis and trimethoprim-sulfamethoxazole. Complete remission after a twenty-year course.
    Annals of internal medicine, 1987, Volume: 106, Issue:6

    Topics: Blood Sedimentation; Cyclophosphamide; Drug Combinations; Drug Therapy, Combination; Female; Granulo

1987
Wegener granulomatosis and trimethoprim-sulfamethoxazole.
    Annals of internal medicine, 1987, Volume: 107, Issue:4

    Topics: Adolescent; Drug Combinations; Female; Granulomatosis with Polyangiitis; Humans; Nose Diseases; Sulf

1987
Wegener's granulomatosis: observations on treatment with antimicrobial agents.
    Mayo Clinic proceedings, 1985, Volume: 60, Issue:1

    Topics: Adult; Aged; Cyclophosphamide; Drug Combinations; Drug Therapy, Combination; Female; Granulomatosis

1985
[Treatment of Wegener's granuloma with immunosuppressive and steroid drugs (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1974, Volume: 53, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Cephalothin; Granulomatosis with Polyangiitis; Humans;

1974
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