Page last updated: 2024-08-26

sr 48968 and Cough

sr 48968 has been researched along with Cough in 11 studies

*Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (72.73)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anthes, JC; Billah, M; Carruthers, N; Chapman, RW; Corboz, M; Crawley, Y; Cuss, FM; Eckel, S; Egan, RW; Fernandez, X; Greenfeder, S; Hey, JA; Kreutner, W; McLeod, R; Piwinski, J; Reichard, G; Richard, C; Rizzo, C; Sehring, S; Shih, NY; Ting, P1
El-Hashim, AZ; Lewis, C; Wyss, D1
Advenier, C; Emonds-Alt, X; Girard, V; Naline, E; Vilain, P2
Hirayama, Y; Hiroi, J; Imai, T; Miyayasu, K; Yasumitsu, R1
Advenier, C1
Bolser, DC; DeGennaro, FC; Hey, JA; McLeod, RL; O'Reilly, S1
Advenier, C; Cognon, C; Daoui, S; Emonds-Alt, X; Naline, E1
Dong, F; Hasegawa, S; Iijima, H; Nomura, A; Uchida, Y; Xiang, A; Zhang, MJ1
Beerens, D; Gustin, P; Moreaux, B1
Advenier, C; Beerens, D; Gustin, P; Halloy, D; Moreaux, B; Nemmar, A; Vincke, G1

Reviews

1 review(s) available for sr 48968 and Cough

ArticleYear
Tachykinin NK2 receptors further characterized in the lung with nonpeptide receptor antagonists.
    Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:7

    Topics: Animals; Asthma; Benzamides; Bronchoconstriction; Cough; Humans; Lung; Piperidines; Receptors, Neurokinin-2

1995

Other Studies

10 other study(ies) available for sr 48968 and Cough

ArticleYear
SCH 206272: a potent, orally active tachykinin NK(1), NK(2), and NK(3) receptor antagonist.
    European journal of pharmacology, 2002, Aug-23, Volume: 450, Issue:2

    Topics: Acetamides; Administration, Oral; Animals; Bronchoconstriction; Capillary Permeability; Capsaicin; CHO Cells; Cough; Cricetinae; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Piperidines; Pulmonary Artery; Radioligand Assay; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Vas Deferens

2002
Effect of a novel NK1 receptor selective antagonist (NKP608) on citric acid induced cough and airway obstruction.
    Pulmonary pharmacology & therapeutics, 2004, Volume: 17, Issue:1

    Topics: Airway Obstruction; Animals; Benzamides; Citric Acid; Cough; Guinea Pigs; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Plethysmography; Quinolines

2004
Effect of the two tachykinin antagonists, SR 48968 and SR 140333, on cough induced by citric acid in the unanaesthetized guinea pig.
    The European respiratory journal, 1995, Volume: 8, Issue:7

    Topics: Administration, Inhalation; Aerosols; Albuterol; Animals; Antitussive Agents; Benzamides; Bronchoconstriction; Bronchodilator Agents; Codeine; Cough; Drug Synergism; Female; Guinea Pigs; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Stereoisomerism

1995
Antitussive effect of SR 48968, a non-peptide tachykinin NK2 receptor antagonist.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Animals; Antitussive Agents; Benzamides; Citrates; Citric Acid; Codeine; Cough; Dose-Response Relationship, Drug; Female; Guinea Pigs; Injections, Intraperitoneal; Male; Naloxone; Piperidines; Receptors, Neurokinin-2

1993
Effects of specific tachykinin receptor antagonists on citric acid-induced cough and bronchoconstriction in unanesthetized guinea pigs.
    European journal of pharmacology, 1996, Apr-11, Volume: 300, Issue:3

    Topics: Animals; Antacids; Benzamides; Bronchoconstriction; Citric Acid; Cough; Dipeptides; Guinea Pigs; Indoles; Male; Piperidines

1996
Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat.
    British journal of pharmacology, 1997, Volume: 121, Issue:2

    Topics: Animals; Antitussive Agents; Benzamides; Cats; Central Nervous System; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Piperidines

1997
Involvement of tachykinin NK3 receptors in citric acid-induced cough and bronchial responses in guinea pigs.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:1

    Topics: Animals; Benzamides; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Citric Acid; Cough; Female; Guinea Pigs; Male; Piperidines; Receptors, Neurokinin-2; Receptors, Neurokinin-3

1998
Effects of airway inflammation on cough response in the guinea pig.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:5

    Topics: Animals; Antitussive Agents; Benzamides; Bronchoalveolar Lavage Fluid; Capsaicin; Codeine; Cough; Dipeptides; Female; Guinea Pigs; Indoles; Inflammation; Peptides, Cyclic; Piperidines; Quinuclidines; Receptors, Neurokinin-2; Receptors, Tachykinin; Respiratory Hypersensitivity; Respiratory Tract Diseases

1998
Development of a cough induction test in pigs: effects of SR 48968 and enalapril.
    Journal of veterinary pharmacology and therapeutics, 1999, Volume: 22, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzamides; Citric Acid; Cough; Dose-Response Relationship, Drug; Enalapril; Female; Male; Nebulizers and Vaporizers; Piperidines; Receptors, Neurokinin-2; Swine

1999
Role of substance P and tachykinin receptor antagonists in citric acid-induced cough in pigs.
    European journal of pharmacology, 2000, Nov-24, Volume: 408, Issue:3

    Topics: Animals; Benzamides; Citric Acid; Cough; Female; Lung; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Reflex; Substance P; Swine, Miniature

2000