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spironolactone and Arthritis, Juvenile Chronic

spironolactone has been researched along with Arthritis, Juvenile Chronic in 3 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Research Excerpts

ExcerptRelevanceReference
"Spironolactone therapy was generally well tolerated, although treatment had to be stopped in two adults on concomitant methotrexate therapy."5.32Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis. ( Bendtzen, K; Hansen, PR; Rieneck, K, 2003)
"A rare case of childhood pulmonary haemosiderosis with juvenile idiopathic arthritis is discussed, with particular reference to treatment with hydroxychloroquine and sildenafil for pulmonary hypertension which occurs secondary to this disease."3.74Pulmonary haemosiderosis with juvenile idiopathic arthritis in a Malaysian child. ( Noor, AS; Quah, BS; Rasool, AH; Roberton, D; Wong, AR, 2007)
"Spironolactone therapy was generally well tolerated, although treatment had to be stopped in two adults on concomitant methotrexate therapy."1.32Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis. ( Bendtzen, K; Hansen, PR; Rieneck, K, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wong, AR1
Noor, AS1
Rasool, AH1
Quah, BS1
Roberton, D1
Bendtzen, K2
Hansen, PR2
Rieneck, K2

Other Studies

3 other studies available for spironolactone and Arthritis, Juvenile Chronic

ArticleYear
Pulmonary haemosiderosis with juvenile idiopathic arthritis in a Malaysian child.
    The Medical journal of Malaysia, 2007, Volume: 62, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Female; Hemosideros

2007
Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis.
    Clinical and experimental immunology, 2003, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid

2003
[Spironolactone inhibits production of proinflammatory cytokines, including tumor necrosis factor-alpha and interferon-gamma and has potential effect in the treatment of arthritis].
    Ugeskrift for laeger, 2004, Sep-06, Volume: 166, Issue:37

    Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid

2004
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