silicon has been researched along with Diarrhea* in 4 studies
1 review(s) available for silicon and Diarrhea
Article | Year |
---|---|
[The use of actapulgite for the treatment of acute diarrhea in infants and children. Review of pediatric studies].
Epidemiological data on diarrhea due to Rotavirus are similar enough across different regions of the world to allow the pooling of clinical studies of Actapulgite for the treatment of acute diarrhea in infants and children in France and Africa. A total of 7,616 infants and children were entered into these open or placebo-controlled trials. Most patients were under two years of age, results of the analysis confirmed the antidiarrheal efficacy and safety of Actapulgite. Topics: Acute Disease; Adolescent; Africa; Child; Child, Preschool; Clinical Trials as Topic; Diarrhea; Diarrhea, Infantile; France; Humans; Infant; Infant, Newborn; Magnesium; Magnesium Compounds; Rotavirus Infections; Silicon; Silicon Compounds | 1993 |
2 trial(s) available for silicon and Diarrhea
Article | Year |
---|---|
[Therapeutic evaluation of Mormoiron attapulgite in acute diarrheas of infants and children. A multicenter study in controlled liberal practice versus placebo in 113 patients].
A placebo-controlled multicenter study was carried out to evaluate the effectiveness and safety of Actapulgite in infants and children with acute diarrhea. One hundred and thirteen patients, with a mean age of 28 months, were enrolled by pediatricians in the office. As recommended during acute diarrhea, the dosage of Actapulgite was doubled during the first three treatment days (2 to 4 packets a day according to the patient's weight), and reduced by half thereafter. The main effectiveness criteria was passage of the first normally formed stool, which denotes normalization of intestinal transit time. The first normally formed stool was recorded after two days of treatment with Actapulgite and was followed, on the next day, by a second normal stool, denoting complete recovery. The greater effectiveness of Actapulgite as compared with the placebo was demonstrated by the fact that both the first and the second normally formed stools were passed one day earlier with the active treatment (p = 0.01 and p = 0.002, respectively). In addition, resumption of a normal diet occurred significantly earlier with Actapulgite (4.4 days) than with the placebo (5.1 days). In addition to being effective, the study drug proved remarkably well tolerated. This study is especially valuable because of its office setting and the use of exclusively clinical criteria with a strict methodology. Topics: Acute Disease; Adolescent; Child; Child, Preschool; Diarrhea; Diarrhea, Infantile; Double-Blind Method; Female; Humans; Infant; Magnesium; Magnesium Compounds; Male; Placebos; Silicon; Silicon Compounds | 1992 |
A randomized, open-label comparison of nonprescription loperamide and attapulgite in the symptomatic treatment of acute diarrhea.
The efficacy of nonprescription doses of loperamide hydrochloride (Imodium A-D) was compared with nonfibrous activated attapulgite (Diasorb) in a randomized, parallel, open-label study of adult patients with acute diarrhea. The results of the study showed loperamide to be more effective than attapulgite in the control of diarrhea. Loperamide significantly reduced stool frequency compared with attapulgite, particularly within the first 12-hour period following the start of therapy, and significantly shortened the mean time to last unformed stool (loperamide, 14.2 hours, versus attapulgite, 19.5 hours). Subjective evaluations of severity of enteric symptoms, overall relief following treatment, and overall relief after 48 hours of treatment were equivalent for both drugs. Both treatments were well tolerated, and there was no difference between treatments with respect to the proportion of patients reporting adverse experiences. Topics: Acute Disease; Adult; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Loperamide; Magnesium; Magnesium Compounds; Male; Nonprescription Drugs; Piperidines; Randomized Controlled Trials as Topic; Silicon; Silicon Compounds | 1990 |
1 other study(ies) available for silicon and Diarrhea
Article | Year |
---|---|
The effect of deionization and drying of cane molasses on their laxative action in chickens.
Topics: Animal Feed; Animals; Calcium; Cathartics; Chickens; Chlorides; Diarrhea; Freeze Drying; Hot Temperature; Ion Exchange Resins; Iron; Magnesium; Molasses; Phosphates; Potassium; Poultry Diseases; Silicon; Sodium | 1972 |