Page last updated: 2024-11-04

sevoflurane and Liver Dysfunction

sevoflurane has been researched along with Liver Dysfunction in 19 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
" Previous studies have demonstrated that sevoflurane, a volatile anesthetic, can preserve the endothelial glycocalyx in heart tissues against ischemia-reperfusion injury."7.83Protective effects of sevoflurane in hepatic ischemia-reperfusion injury. ( Li, J; Liu, HQ; Lv, GY; Yuan, T; Zhao, X, 2016)
"After approval by the institutional animal care and use committee, 36 Japanese White rabbits underwent partial hepatic ischemia for 90 min either under sevoflurane or propofol anesthesia."3.88Interaction between anesthetic conditioning and ischemic preconditioning on metabolic function after hepatic ischemia-reperfusion in rabbits. ( Kosugi, S; Kotake, Y; Morisaki, H; Nagata, H; Suzuki, T; Yamada, T, 2018)
"The study shows that sevoflurane postconditioning affects apoptosis of hepatocytes after ischemia-reperfusion injury in patients."3.88Sevoflurane Protects Hepatocytes From Ischemic Injury by Reducing Reactive Oxygen Species Signaling of Hepatic Stellate Cells: Translational Findings Based on a Clinical Trial. ( Beck-Schimmer, B; Booy, C; Köppel, S; Roth Z'graggen, B; Schadde, E; Schläpfer, M; Spahn, DR, 2018)
" Previous studies have demonstrated that sevoflurane, a volatile anesthetic, can preserve the endothelial glycocalyx in heart tissues against ischemia-reperfusion injury."3.83Protective effects of sevoflurane in hepatic ischemia-reperfusion injury. ( Li, J; Liu, HQ; Lv, GY; Yuan, T; Zhao, X, 2016)
"The liver of all rats given halothane (14% O(2)) had extensive centrilobular necrosis and denaturation."3.73Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats. ( Li, Q; Liu, ZQ; Yang, LQ; Yu, WF; Zhou, MT, 2005)
"Hepatic ischemia-reperfusion injury has a significant impact on liver resection and transplantation."1.40Ischemic versus pharmacologic hepatic preconditioning. ( Azambuja, G; Balzan, SM; de Souza, PL; Gava, VG; Horta, JA; Pra, D; Rieger, A; Schopf, L; Trombini, L; Zenkner, FF, 2014)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (21.05)18.2507
2000's2 (10.53)29.6817
2010's8 (42.11)24.3611
2020's5 (26.32)2.80

Authors

AuthorsStudies
Jester, N1
Kang, P1
Steele, M1
Howells, L1
Santer, M1
Sivyer, K1
Lawton, S1
Roberts, A1
Teasdale, E1
Muller, I1
Greenwell, K1
Silva, LP1
Silva, TA1
Moraes, FC1
Fatibello-Filho, O1
Durrani, TS1
Farooqi, A1
Zhang, J3
Xu, C1
Gao, L1
Zhang, D1
Li, C1
Liu, J1
Jiang, PP1
Guo, YX1
Yang, XL1
Xu, J1
Wang, D1
Liu, P1
Zhong, L1
Huang, S1
Gong, L1
Han, D1
Wang, S1
Xiao, M1
Meng, Y1
Kraemer, R1
Smith, HJ1
Matthys, H1
Xin, D1
Bai, Y1
Bi, Y1
He, L1
Kang, Y1
Pan, C1
Zhu, H1
Chen, H1
Qu, L1
Lan, X1
Tong, Y1
Wang, L1
Wang, Q1
Huang, H1
Chen, X1
Zhang, Q1
Li, H3
Sun, N1
Liu, G1
Zhang, B1
Song, F1
Alterovitz, G1
Dai, H1
Zhang, L1
Ji, H1
Zhang, H1
Cheng, Z1
Benoit, L1
Dieu, A1
Foguenne, M1
Bonaccorsi-Riani, E1
Ma, H1
Yang, B1
Yu, L1
Gao, Y1
Ye, X1
Liu, Y1
Li, Z1
Li, E1
Xiao, X1
Liu, D1
Chen, S1
Li, X1
Ge, M1
Huang, W1
Yamada, T1
Nagata, H1
Kosugi, S1
Suzuki, T1
Morisaki, H1
Kotake, Y1
Beck-Schimmer, B3
Roth Z'graggen, B1
Booy, C1
Köppel, S1
Spahn, DR2
Schläpfer, M1
Schadde, E1
Nguyen, TM1
Fleyfel, M1
Boleslawski, E1
M'Ba, L1
Geniez, M1
Ethgen, S1
Béhal, H1
Lebuffe, G1
Balzan, SM1
Gava, VG1
Rieger, A1
Pra, D1
Trombini, L1
Zenkner, FF1
Horta, JA1
Azambuja, G1
Schopf, L1
de Souza, PL1
Li, J1
Yuan, T1
Zhao, X1
Lv, GY1
Liu, HQ1
Granja, TF1
Köhler, D1
Schad, J1
de Oliveira, CB1
Konrad, F1
Hoch-Gutbrod, M1
Streienberger, A1
Rosenberger, P1
Straub, A1
Eichler, K1
Urner, M1
Twerenbold, C1
Kern, S1
Brügger, U1
Ganter, MT1
Slankamenac, K1
Breitenstein, S1
Graf, R1
Puhan, MA1
Clavien, PA1
Yu, WF1
Yang, LQ1
Zhou, MT1
Liu, ZQ1
Li, Q1
Lorsomradee, S2
Cromheecke, S1
De Hert, SG1
Fukuda, H1
Saitoh, K1
Saitoh, J1
Hirabayashi, Y1
Mitsuhata, H1
Kasuda, H1
Shimizu, R1
Bito, H1
Ikeda, K1
Eger, EI1
Gong, D1
Koblin, DD1
Bowland, T1
Ionescu, P1
Laster, MJ1
Weiskopf, RB1
Shichinohe, Y1
Masuda, Y1
Takahashi, H1
Kotaki, M1
Omote, T1
Shichinohe, M1
Namiki, A1

Reviews

2 reviews available for sevoflurane and Liver Dysfunction

ArticleYear
    Public health in practice (Oxford, England), 2021, Volume: 2

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Antifungal Agents; Antirheumatic

2021
Experimental and Clinical Aspects of Sevoflurane Preconditioning and Postconditioning to Alleviate Hepatic Ischemia-Reperfusion Injury: A Scoping Review.
    International journal of molecular sciences, 2023, Jan-25, Volume: 24, Issue:3

    Topics: Humans; Ischemia; Liver Diseases; Reperfusion Injury; Sevoflurane

2023

Trials

4 trials available for sevoflurane and Liver Dysfunction

ArticleYear
    Public health in practice (Oxford, England), 2021, Volume: 2

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Antifungal Agents; Antirheumatic

2021
Economic Evaluation of Pharmacologic Pre- and Postconditioning With Sevoflurane Compared With Total Intravenous Anesthesia in Liver Surgery: A Cost Analysis.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:3

    Topics: Adult; Aged; Anesthesia, Intravenous; Cost-Benefit Analysis; Female; Humans; Length of Stay; Liver D

2017
Effects of sevoflurane on biomechanical markers of hepatic and renal dysfunction after coronary artery surgery.
    Journal of cardiothoracic and vascular anesthesia, 2006, Volume: 20, Issue:5

    Topics: Administration, Inhalation; Aged; Alanine Transaminase; Anesthesia, General; Anesthetics, Inhalation

2006
Renal and hepatic function in surgical patients after low-flow sevoflurane or isoflurane anesthesia.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:1

    Topics: Adult; Aged; Alanine Transaminase; Anesthesia, General; Anesthetics, Inhalation; Aspartate Aminotran

1996

Other Studies

14 other studies available for sevoflurane and Liver Dysfunction

ArticleYear
Role of microRNA‑218‑5p in sevoflurane‑induced protective effects in hepatic ischemia/reperfusion injury mice by regulating GAB2/PI3K/AKT pathway.
    Molecular medicine reports, 2022, Volume: 25, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Ischemia; Liver; Liver Diseases; Male; Mic

2022
Sevoflurane protects the liver from ischemia-reperfusion injury by regulating Nrf2/HO-1 pathway.
    European journal of pharmacology, 2021, May-05, Volume: 898

    Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Heme Oxygenase (Decyclizing); Heme Oxygenase-

2021
Sevoflurane preconditioning activates HGF/Met-mediated autophagy to attenuate hepatic ischemia-reperfusion injury in mice.
    Cellular signalling, 2021, Volume: 82

    Topics: Animals; Apoptosis; Hepatocyte Growth Factor; Hepatocytes; Liver Diseases; Male; Mice; Mice, Inbred

2021
Interaction between anesthetic conditioning and ischemic preconditioning on metabolic function after hepatic ischemia-reperfusion in rabbits.
    Journal of anesthesia, 2018, Volume: 32, Issue:4

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Hemodynamics; Ischemic Precond

2018
Sevoflurane Protects Hepatocytes From Ischemic Injury by Reducing Reactive Oxygen Species Signaling of Hepatic Stellate Cells: Translational Findings Based on a Clinical Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:4

    Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Culture Media, Conditioned; C

2018
Effect of pharmacological preconditioning with sevoflurane during hepatectomy with intermittent portal triad clamping.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2019, Volume: 21, Issue:9

    Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Constriction; Female; Hepatectomy; Humans;

2019
Ischemic versus pharmacologic hepatic preconditioning.
    The Journal of surgical research, 2014, Volume: 191, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Bilirubin; Biomarkers; C-Reactive Protein; DNA Damage; Ischemic Pr

2014
Protective effects of sevoflurane in hepatic ischemia-reperfusion injury.
    International journal of immunopathology and pharmacology, 2016, Volume: 29, Issue:2

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Endothelium; Fe

2016
Adenosine Receptor Adora2b Plays a Mechanistic Role in the Protective Effect of the Volatile Anesthetic Sevoflurane during Liver Ischemia/Reperfusion.
    Anesthesiology, 2016, Volume: 125, Issue:3

    Topics: Adult; Anesthetics, Inhalation; Animals; Disease Models, Animal; Humans; Liver; Liver Diseases; Meth

2016
Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery?
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2012, Volume: 14, Issue:12

    Topics: Administration, Inhalation; Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Anesthetics,

2012
Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats.
    World journal of gastroenterology, 2005, Aug-28, Volume: 11, Issue:32

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Calcium; Chemical and Drug Induced Liver Inj

2005
[Changes in plasma concentrations of human hepatocyte growth factor before and after major intra-abdominal surgery under nitrous oxide-sevoflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:10

    Topics: Abdomen; Aged; Aged, 80 and over; Anesthesia, Inhalation; Ethers; Female; Hepatocyte Growth Factor;

1994
Dose-related biochemical markers of renal injury after sevoflurane versus desflurane anesthesia in volunteers.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Biomarkers; Chemical and Drug Induced Liver Inj

1997
[A case of postoperative hepatic injury after sevoflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:11

    Topics: Anesthesia, Inhalation; Anesthetics; Cross Reactions; Enflurane; Ethers; Humans; Liver Diseases; Mal

1992
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