Page last updated: 2024-11-04
sevoflurane and Ache
sevoflurane has been researched along with Ache in 58 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since the introduction of propofol, several drugs and methods have been used to alleviate the pain on its injection." | 9.15 | Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011) |
| "Omission of fentanyl did not reduce the overall incidence of postoperative nausea and vomiting, but did reduce the incidence of vomiting and/or moderate to severe nausea prior to discharge from 20% and 17% with fentanyl and fentanyl-dexamethasone, respectively, to 5% (P = 0." | 9.13 | Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery. ( Bridgman, S; Smith, I; Walley, G, 2008) |
| "We investigated the early recovery characteristics and pain relief of adult patients during combined anesthesia with (epidural and general), either with propofol or sevoflurane for maintenance in major abdominal surgery." | 9.11 | Propofol and sevoflurane during epidural/general anesthesia: comparison of early recovery characteristics and pain relief. ( Duru, S; Elar, Z; Hepağuşlar, H; Ozkardeşler, S; Ozzeybek, D; Taşdöğen, A, 2004) |
| "The general anesthetic sevoflurane is being repurposed as a topical analgesic for painful chronic wounds." | 8.02 | Cost-effectiveness analysis of domiciliary topical sevoflurane for painful leg ulcers. ( Cortiñas-Sáenz, M; Fernández-Ginés, FD; Gerónimo-Pardo, M; Selva-Sevilla, C, 2021) |
| "To investigate the correlation between the pain rating index (PRi), which is an index derived from processed electroencephalography signals, and the end-tidal sevoflurane concentration (ETsevo)." | 8.02 | Correlation between pain rating index and end-tidal sevoflurane concentration during sevoflurane anesthesia. ( Lv, ZG; Wang, BG; Wang, Z; Zhang, JW; Zhang, WW, 2021) |
| "Recently, it has been reported that topical irrigations of liquid sevoflurane on the bed of painful wounds produce a rapid, intense, and lasting analgesic effect." | 7.96 | Pain reduction of topical sevoflurane vs intravenous opioids in pressure ulcers. ( Agudo-Ponce, D; Cortiñas-Sáenz, M; Fernández-Ginés, FD; Fernández-Sánchez, C; Mateo-Carrasco, H; Morales-Molina, JA; Navajas-Gómez de Aranda, A; Sierra-García, F, 2020) |
| "The aim of this study is to evaluate the use and safety of a sedation protocol with sevoflurane for short painful procedures in newborns." | 7.91 | Sevoflurane for Short Painful Procedures in the Neonatal Intensive Care Unit. ( Cabrera, M; Elorza, MD; Gomez, F; Lopez-Ortego, P; Sanabria, P; Sanchez, L, 2019) |
| "Topical application of sevoflurane to painful wounds produced a rapid, robust, and long-lasting analgesic effect, which allowed for a high degree of wound debridement." | 7.91 | Analgesic effectiveness of topical sevoflurane to perform sharp debridement of painful wounds. ( Gerónimo-Pardo, M; Martínez-Monsalve, A; Selva-Sevilla, C, 2019) |
| " Finally, intrathecal L-arginine alone did not affect the basal pain threshold, but it significantly decreased the antinociceptive response of emulsified sevoflurane against formalin injection and the suppressive effects of sevoflurane on formalin-induced Fos protein expression (P<0." | 7.81 | Intrathecal L-arginine reduces the antinociception of sevoflurane in formalin-induced pain in rats. ( Chen, JQ; Dai, TJ; Tang, QF; Zeng, YM, 2015) |
| "Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia." | 7.78 | Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia. ( Chung, WY; Hong, JY; Kil, HK; Kim, GH; Kim, WO; Seo, H, 2012) |
| "These findings show that sevoflurane administration after ischemia does not provide neuroprotection in rats subjected to incomplete cerebral ischemia." | 7.76 | Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in rats. ( Choi, JH; DO, HS; Jee, DL; Kim, YW; Lee, DH; Lee, HM; Lee, SR; Park, SJ, 2010) |
| "The aim of the present study was to examine the level of unconsciousness measured with bispectral index (BIS) at different minimal alveolar concentration (MAC) levels of sevoflurane, and to study the hemodynamic and BIS reactions during noxious stimulation with transcutaneous electrical nerve stimulation (TENS) and an ice water pain test (IWP)." | 7.74 | Effects of pain stimulation on bispectral index, heart rate and blood pressure at different minimal alveolar concentration values of sevoflurane. ( Axelsson, K; Dahlqvist, A; Sandin, M; Thörn, SE; Wattwil, L; Wattwil, M, 2008) |
| "The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia." | 7.72 | Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004) |
| "Pain caused an increase in prehypoxic baseline ventilation before and during sevoflurane inhalation: C = 13." | 7.69 | Acute pain and central nervous system arousal do not restore impaired hypoxic ventilatory response during sevoflurane sedation. ( Berkenbosch, A; Dahan, A; Olofsen, E; Sarton, E; Teppema, L; van den Elsen, M; van Kleef, J, 1996) |
| "Sevoflurane consumption was lower in PRi group than in SBP group (15." | 7.01 | Comparison of blood pressure and pain rating index used for depth regulation of sevoflurane anaesthesia. ( Bai, L; Lv, Z; Wang, B; Zhang, J, 2021) |
| " However, no significant intergroup differences were observed in the pain score, parental satisfaction, the incidence of propofol rescue and NPOBCs." | 5.69 | Sucking lollipop after awakening from sevoflurane anesthesia reduces the degree of emergence agitation in children undergoing ambulatory surgery: A prospective randomized controlled trial. ( Huang, F; Mo, X; Wu, X; Zeng, J; Zhang, K, 2023) |
| "Since the introduction of propofol, several drugs and methods have been used to alleviate the pain on its injection." | 5.15 | Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011) |
| "To compare the efficacy and safety of sevoflurane deep sedation with glucose and nonnutritive sucking (GNNS) in reducing the duration of the procedure and in preventing pain-related effects during peripherally inserted central catheter (PICC) placement." | 5.14 | Sevoflurane for central catheter placement in neonatal intensive care: a randomized trial. ( DI Marco, JN; Garbi, A; Hassid, S; Lagier, P; Martin, C; Michel, F; Nicaise, C; Thomachot, L; Vialet, R, 2010) |
| "Omission of fentanyl did not reduce the overall incidence of postoperative nausea and vomiting, but did reduce the incidence of vomiting and/or moderate to severe nausea prior to discharge from 20% and 17% with fentanyl and fentanyl-dexamethasone, respectively, to 5% (P = 0." | 5.13 | Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery. ( Bridgman, S; Smith, I; Walley, G, 2008) |
| "We investigated the early recovery characteristics and pain relief of adult patients during combined anesthesia with (epidural and general), either with propofol or sevoflurane for maintenance in major abdominal surgery." | 5.11 | Propofol and sevoflurane during epidural/general anesthesia: comparison of early recovery characteristics and pain relief. ( Duru, S; Elar, Z; Hepağuşlar, H; Ozkardeşler, S; Ozzeybek, D; Taşdöğen, A, 2004) |
| "To investigate the correlation between the pain rating index (PRi), which is an index derived from processed electroencephalography signals, and the end-tidal sevoflurane concentration (ETsevo)." | 4.02 | Correlation between pain rating index and end-tidal sevoflurane concentration during sevoflurane anesthesia. ( Lv, ZG; Wang, BG; Wang, Z; Zhang, JW; Zhang, WW, 2021) |
| "The general anesthetic sevoflurane is being repurposed as a topical analgesic for painful chronic wounds." | 4.02 | Cost-effectiveness analysis of domiciliary topical sevoflurane for painful leg ulcers. ( Cortiñas-Sáenz, M; Fernández-Ginés, FD; Gerónimo-Pardo, M; Selva-Sevilla, C, 2021) |
| "Recently, it has been reported that topical irrigations of liquid sevoflurane on the bed of painful wounds produce a rapid, intense, and lasting analgesic effect." | 3.96 | Pain reduction of topical sevoflurane vs intravenous opioids in pressure ulcers. ( Agudo-Ponce, D; Cortiñas-Sáenz, M; Fernández-Ginés, FD; Fernández-Sánchez, C; Mateo-Carrasco, H; Morales-Molina, JA; Navajas-Gómez de Aranda, A; Sierra-García, F, 2020) |
| "The aim of this study is to evaluate the use and safety of a sedation protocol with sevoflurane for short painful procedures in newborns." | 3.91 | Sevoflurane for Short Painful Procedures in the Neonatal Intensive Care Unit. ( Cabrera, M; Elorza, MD; Gomez, F; Lopez-Ortego, P; Sanabria, P; Sanchez, L, 2019) |
| "Topical application of sevoflurane to painful wounds produced a rapid, robust, and long-lasting analgesic effect, which allowed for a high degree of wound debridement." | 3.91 | Analgesic effectiveness of topical sevoflurane to perform sharp debridement of painful wounds. ( Gerónimo-Pardo, M; Martínez-Monsalve, A; Selva-Sevilla, C, 2019) |
| "Analgesic mouse models were established by intraperitoneal injection of emulsified sevoflurane, and the influence of p-MPPF (a specific antagonist of 5-HT1A Rs) intrathecal injection on the changes in tail-flick latency in tail-withdrawal test, pain threshold in hot-plate test (HPPT), and writhing times in acetic acid-induced writhing test were recorded." | 3.85 | 5-HT1A Receptors Mediate Analgesia Induced by Emulsified Sevoflurane in Thermal Nociception but Have Little Effect on Chemical Nociception. ( Gao, C; Hong, T; Shen, J; Ti-Jun, D; Xin, L; Yan, C; Zhi-Xiu, M, 2017) |
| "This study suggests that sevoflurane, but not intravenous anesthetics, inhibits pain-related anxiety, along with ERK activation in the ACC, probably through inhibition of spinal nociceptive transmission." | 3.81 | Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex. ( Dai, RP; Li, CQ; Luo, C; Luo, W; Xu, JM; Zhang, YL; Zhou, FH, 2015) |
| " Finally, intrathecal L-arginine alone did not affect the basal pain threshold, but it significantly decreased the antinociceptive response of emulsified sevoflurane against formalin injection and the suppressive effects of sevoflurane on formalin-induced Fos protein expression (P<0." | 3.81 | Intrathecal L-arginine reduces the antinociception of sevoflurane in formalin-induced pain in rats. ( Chen, JQ; Dai, TJ; Tang, QF; Zeng, YM, 2015) |
| "Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia." | 3.78 | Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia. ( Chung, WY; Hong, JY; Kil, HK; Kim, GH; Kim, WO; Seo, H, 2012) |
| " Baseline brain activity was altered by inducing anesthesia (sevoflurane end-tidal concentration 1%) in human volunteers and fc-fMRI maps between the pre-anesthetized and anesthetized conditions were compared across different brain networks." | 3.76 | Functional connectivity and alterations in baseline brain state in humans. ( Constable, RT; Martuzzi, R; Qiu, M; Rajeevan, N; Ramani, R, 2010) |
| "These findings show that sevoflurane administration after ischemia does not provide neuroprotection in rats subjected to incomplete cerebral ischemia." | 3.76 | Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in rats. ( Choi, JH; DO, HS; Jee, DL; Kim, YW; Lee, DH; Lee, HM; Lee, SR; Park, SJ, 2010) |
| " After having established the mice model of hypnosis and analgesia by intraperitoneal injections of appropriate doses of enflurane, isoflurane or sevoflurane, we intracerebroventricularly or intrathecally injected different doses of nicotine and then observed the effects on the sleeping time using awaken test and the pain threshold in hot-plate test (HPPT) using hot-plate test." | 3.75 | Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics. ( Dai, TJ; Yan, S; Zeng, YM, 2009) |
| " After having established the mouse model of analgesia by intraperitoneal or subcutaneous injections of appropriate doses of emulsified enflurane, isoflurane or sevoflurane, we injected different doses of AMPA intrathecally and observed effects on the pain threshold using the hot-plate and acetic acid-induced writhing tests." | 3.74 | Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics. ( Dai, TJ; Hang, LH; Shao, DH; Yang, YH; Zeng, YM, 2007) |
| "The aim of the present study was to examine the level of unconsciousness measured with bispectral index (BIS) at different minimal alveolar concentration (MAC) levels of sevoflurane, and to study the hemodynamic and BIS reactions during noxious stimulation with transcutaneous electrical nerve stimulation (TENS) and an ice water pain test (IWP)." | 3.74 | Effects of pain stimulation on bispectral index, heart rate and blood pressure at different minimal alveolar concentration values of sevoflurane. ( Axelsson, K; Dahlqvist, A; Sandin, M; Thörn, SE; Wattwil, L; Wattwil, M, 2008) |
| "The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia." | 3.72 | Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004) |
| "Pain caused an increase in prehypoxic baseline ventilation before and during sevoflurane inhalation: C = 13." | 3.69 | Acute pain and central nervous system arousal do not restore impaired hypoxic ventilatory response during sevoflurane sedation. ( Berkenbosch, A; Dahan, A; Olofsen, E; Sarton, E; Teppema, L; van den Elsen, M; van Kleef, J, 1996) |
| "Sevoflurane consumption was lower in PRi group than in SBP group (15." | 3.01 | Comparison of blood pressure and pain rating index used for depth regulation of sevoflurane anaesthesia. ( Bai, L; Lv, Z; Wang, B; Zhang, J, 2021) |
| "Rocuronium 0." | 2.76 | A short period of inhalation induction with sevoflurane prevents rocuronium-induced withdrawal in children. ( Goo, EK; Hwang, JW; Kim, CS; Kim, JH; Min, SW; Nahm, FS; Oh, AY; Park, SH; Shin, NR, 2011) |
| "Times to early emergence and tracheal extubation were significantly shorter with LFGF SS than TCI (5." | 2.73 | Low fresh gas flow balanced anesthesia versus target controlled intravenous infusion anesthesia in laparoscopic cholecystectomy: a cost-minimization analysis. ( Dobrasinovic, J; Miljkovic, B; Perunovic, R; Petrova, G; Scepanovic, R; Stevanovic, PD; Stojanovic, D, 2008) |
| "Sevoflurane is a volatile liquid from the family of ether-derived alogenated hydrocarbons that is approved for the induction and maintenance of inhalational general anesthesia in the hospital setting." | 2.72 | Topical sevofluran: a galenic experience. ( Cortiñas-Sáenz, M; Fernández-Ginés, FD; Gerónimo-Pardo, M, 2021) |
| "Increasingly more aged people with Alzheimer's disease (AD) must undergo surgery with general anesthesia for various reasons." | 1.40 | Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice. ( Deng, Y; He, Z; Lu, B; Qi, B; Su, D; Tian, J; Wang, X; Xu, H; Zheng, B, 2014) |
| "Sevoflurane MAC was not significantly reduced by N2O and its antinociceptive action was almost completely abolished in KOP-knockout (KO) mice." | 1.40 | κ-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice. ( Fukagawa, H; Fukuda, K; Koyama, T, 2014) |
| "Lidocaine was injected percutaneously at the sciatic nerve in volumes of 0." | 1.32 | The critical role of concentration for lidocaine block of peripheral nerve in vivo: studies of function and drug uptake in the rat. ( Birknes, J; Nakamura, T; Popitz-Bergez, F; Strichartz, GR, 2003) |
Research
Studies (58)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (12.07) | 18.2507 |
| 2000's | 18 (31.03) | 29.6817 |
| 2010's | 23 (39.66) | 24.3611 |
| 2020's | 10 (17.24) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Selva-Sevilla, C | 2 |
| Fernández-Ginés, FD | 3 |
| Cortiñas-Sáenz, M | 4 |
| Gerónimo-Pardo, M | 3 |
| Liang, X | 1 |
| Chen, P | 1 |
| Chen, C | 1 |
| Che, W | 1 |
| Yang, Y | 1 |
| Tan, Z | 1 |
| Li, H | 1 |
| Zhou, Y | 1 |
| Yin, S | 1 |
| To, MK | 1 |
| Niu, Q | 1 |
| Estephan, LE | 2 |
| Sussman, S | 1 |
| Stewart, M | 1 |
| Zhan, T | 1 |
| Thaler, A | 1 |
| Boon, M | 1 |
| Hunt, P | 1 |
| Huntley, C | 1 |
| Sagalow, ES | 1 |
| Kumar, AT | 1 |
| Hwang, M | 1 |
| Krein, H | 1 |
| Heffelfinger, R | 1 |
| Zhou, F | 1 |
| Cui, Y | 1 |
| Cao, L | 1 |
| Mo, X | 1 |
| Zeng, J | 1 |
| Wu, X | 1 |
| Huang, F | 1 |
| Zhang, K | 1 |
| Agudo-Ponce, D | 1 |
| Navajas-Gómez de Aranda, A | 1 |
| Morales-Molina, JA | 2 |
| Fernández-Sánchez, C | 2 |
| Sierra-García, F | 2 |
| Mateo-Carrasco, H | 2 |
| Zhang, JW | 1 |
| Lv, ZG | 1 |
| Zhang, WW | 1 |
| Wang, Z | 1 |
| Wang, BG | 1 |
| Zhang, J | 1 |
| Lv, Z | 1 |
| Bai, L | 1 |
| Wang, B | 1 |
| Yan, C | 1 |
| Ti-Jun, D | 1 |
| Xin, L | 1 |
| Gao, C | 1 |
| Shen, J | 1 |
| Hong, T | 1 |
| Zhi-Xiu, M | 1 |
| Dámaso Fernández-Ginés, F | 1 |
| de Aranda, AN | 1 |
| Navarro-Muñoz, E | 1 |
| Rodríguez-Carmona, R | 1 |
| Imbernon-Moya, A | 2 |
| Ortiz-de Frutos, FJ | 1 |
| Sanjuan-Alvarez, M | 2 |
| Portero-Sanchez, I | 2 |
| Merinero-Palomares, R | 1 |
| Alcazar, V | 1 |
| Ryu, K | 1 |
| Song, K | 1 |
| Kim, J | 1 |
| Kim, E | 1 |
| Kim, SH | 1 |
| Frutos, JO | 1 |
| Gomez, F | 1 |
| Cabrera, M | 1 |
| Sanabria, P | 1 |
| Sanchez, L | 1 |
| Lopez-Ortego, P | 1 |
| Elorza, MD | 1 |
| Martínez-Monsalve, A | 1 |
| Passariello, M | 1 |
| Almenrader, N | 1 |
| Casado, R | 1 |
| Lumbreras, J | 1 |
| de Inocencio, J | 1 |
| Remesal, A | 1 |
| Merino, R | 1 |
| García-Consuegra, J | 1 |
| Xu, H | 1 |
| Lu, B | 1 |
| Zheng, B | 1 |
| Tian, J | 1 |
| Qi, B | 1 |
| Deng, Y | 1 |
| He, Z | 1 |
| Su, D | 1 |
| Wang, X | 1 |
| Fukagawa, H | 1 |
| Koyama, T | 1 |
| Fukuda, K | 1 |
| Wang, LW | 1 |
| Zhou, MY | 1 |
| Jian, HW | 1 |
| Dai, TJ | 5 |
| Chen, JQ | 1 |
| Zeng, YM | 4 |
| Tang, QF | 1 |
| Luo, C | 1 |
| Zhang, YL | 1 |
| Luo, W | 1 |
| Zhou, FH | 1 |
| Li, CQ | 1 |
| Xu, JM | 1 |
| Dai, RP | 1 |
| Kim, HC | 1 |
| Hong, WP | 1 |
| Lim, YJ | 1 |
| Park, HP | 1 |
| Smith, I | 1 |
| Walley, G | 1 |
| Bridgman, S | 1 |
| Stevanovic, PD | 1 |
| Petrova, G | 1 |
| Miljkovic, B | 1 |
| Scepanovic, R | 1 |
| Perunovic, R | 1 |
| Stojanovic, D | 1 |
| Dobrasinovic, J | 1 |
| Yan, S | 1 |
| Martuzzi, R | 1 |
| Ramani, R | 1 |
| Qiu, M | 1 |
| Rajeevan, N | 1 |
| Constable, RT | 1 |
| Lee, HM | 2 |
| Lee, DH | 1 |
| Choi, JH | 1 |
| Lee, SR | 1 |
| Kim, YW | 1 |
| Jee, DL | 1 |
| DO, HS | 1 |
| Park, SJ | 1 |
| Michel, F | 1 |
| Vialet, R | 1 |
| Hassid, S | 1 |
| Nicaise, C | 1 |
| Garbi, A | 1 |
| Thomachot, L | 1 |
| DI Marco, JN | 1 |
| Lagier, P | 1 |
| Martin, C | 1 |
| Park, SH | 1 |
| Oh, AY | 1 |
| Goo, EK | 1 |
| Nahm, FS | 1 |
| Min, SW | 1 |
| Hwang, JW | 1 |
| Kim, CS | 1 |
| Shin, NR | 1 |
| Kim, JH | 1 |
| DeSousa, K | 1 |
| Ali, MS | 1 |
| Kil, HK | 1 |
| Kim, WO | 1 |
| Chung, WY | 1 |
| Kim, GH | 1 |
| Seo, H | 1 |
| Hong, JY | 1 |
| Constant, I | 1 |
| Sabourdin, N | 1 |
| Untergehrer, G | 1 |
| Jordan, D | 1 |
| Eyl, S | 1 |
| Schneider, G | 1 |
| Kohase, H | 1 |
| Miyamoto, T | 1 |
| Umino, M | 1 |
| Sumikura, H | 1 |
| Arendt-Nielsen, L | 1 |
| Nakamura, T | 1 |
| Popitz-Bergez, F | 1 |
| Birknes, J | 1 |
| Strichartz, GR | 1 |
| Hagihira, S | 1 |
| Takashina, M | 1 |
| Mori, T | 1 |
| Ueyama, H | 1 |
| Mashimo, T | 2 |
| Stekiel, TA | 1 |
| J Contney, S | 1 |
| Bosnjak, ZJ | 1 |
| Kampine, JP | 1 |
| Roman, RJ | 1 |
| Stekiel, WJ | 1 |
| Hepağuşlar, H | 1 |
| Ozzeybek, D | 1 |
| Ozkardeşler, S | 1 |
| Taşdöğen, A | 1 |
| Duru, S | 1 |
| Elar, Z | 1 |
| Garcia-Fernandez, J | 1 |
| Parodi, E | 1 |
| Garcia, P | 1 |
| Matute, E | 1 |
| A-Gomez-de-Segura, I | 1 |
| Cediel, R | 1 |
| Gilsanz, F | 1 |
| Zeidan, A | 1 |
| Grover, S | 1 |
| Wilkinson, DJ | 1 |
| Chen, Y | 1 |
| Hang, LH | 1 |
| Shao, DH | 1 |
| Yang, YH | 1 |
| Ihmsen, H | 1 |
| Schywalsky, M | 1 |
| Plettke, R | 1 |
| Priller, M | 1 |
| Walz, F | 1 |
| Schwilden, H | 1 |
| Sandin, M | 1 |
| Thörn, SE | 1 |
| Dahlqvist, A | 1 |
| Wattwil, L | 1 |
| Axelsson, K | 1 |
| Wattwil, M | 1 |
| Eipe, N | 1 |
| Kay, J | 1 |
| Tomi, K | 1 |
| Tashiro, C | 1 |
| Yagi, M | 1 |
| Pak, M | 1 |
| Nishimura, S | 1 |
| Nishimura, M | 1 |
| Yoshiya, I | 1 |
| Sarton, E | 1 |
| Dahan, A | 2 |
| Teppema, L | 2 |
| van den Elsen, M | 1 |
| Olofsen, E | 1 |
| Berkenbosch, A | 1 |
| van Kleef, J | 1 |
| Hao, S | 1 |
| Ogawa, H | 1 |
| Brown, K | 1 |
| Aun, C | 1 |
| Stocks, J | 1 |
| Jackson, E | 1 |
| Mackersie, A | 1 |
| Hatch, D | 1 |
| Shimoda, O | 1 |
| Ikuta, Y | 1 |
| Nishi, M | 1 |
| Uneda, C | 1 |
| Ma, D | 1 |
| Chakrabarti, MK | 1 |
| Whitwam, JG | 1 |
| Masaki, E | 1 |
| Ebisawa, T | 1 |
| Kondo, I | 1 |
| Hayashida, K | 1 |
| Matsumoto, Y | 1 |
| Kawamura, M | 1 |
Clinical Trials (9)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939] | 15 participants (Anticipated) | Interventional | 2021-08-31 | Not yet recruiting | |||
| Comparison of the Effects of Sevoflurane and Desflurane on Prevention of Catheter-related Bladder Discomfort[NCT02096224] | 108 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| Interest of Using the Sevoflurane in the Prevention of Newborns Pain[NCT00420693] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2006-08-31 | Completed | ||
| The Effect of Preoperative Anxiolysis With Intravenous Midazolam on Intraoperative Sevoflurane Gas Consumption: A Prospective Randomized Controlled Study[NCT05371600] | Phase 4 | 80 participants (Anticipated) | Interventional | 2022-12-02 | Recruiting | ||
| A Randomized Prospective Placebo-Controlled Study of the Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Surgery Patients[NCT01837966] | 93 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| EEG-based Depth of Anesthesia-monitoring During General Anesthesia - Effects on Time to Wake-up and Post-operative Cognition[NCT04529304] | 100 participants (Anticipated) | Interventional | 2021-01-08 | Recruiting | |||
| Efficacy of S(+)-Ketamine Administered as a Continuous Infusion for the Control of Postoperative Pain: a Randomized Controlled Trial[NCT02421913] | Phase 4 | 42 participants (Actual) | Interventional | 2012-06-30 | Completed | ||
| Topical Analgesia Before Inhalational Anaesthesia: A Retrospective Observational Study[NCT04959409] | 500 participants (Actual) | Observational | 2020-08-01 | Completed | |||
| Efficacy and Safety of Methoxyflurane Vaporized (PENTHROX®) in the Treatment of Acute Trauma Pain in Pre-hospital Setting and in the Emergency Department in Italy: a Multicentre, Randomized, Controlled, Open-label Study[NCT03585374] | Phase 3 | 272 participants (Actual) | Interventional | 2018-02-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Anxiety Reduction
We hoped to show that lavender aroma therapy reduces preoperative anxiety in patients undergoing breast. The Trait subscale (STAI-TRAID) of the Spielberger State-Trait Anxiety Inventory was administered before and after 10 minutes of aromatherapy treatment pre-surgery. The TRAIT subscale contains 20 questions scored on a Likert scale from 1-4; item scores are summed for a total score ranging from 20 to 80, with higher scores indicating higher anxiety. Change in anxiety was calculated as the score pre-aromatherapy minus the score post-aromatherapy. Higher positive change scores indicate greater reductions in anxiety. (NCT01837966)
Timeframe: 20 minutes before surgery (pre aromatherapy) and 10 minutes before surgery (post aromatherapy)
| Intervention | units on a scale (Mean) |
|---|---|
| Lavender Oil | 0.89 |
| Placebo | .74 |
Reviews
2 reviews available for sevoflurane and Ache
| Article | Year |
|---|---|
Topical sevofluran: a galenic experience.
Topics: Administration, Topical; Analgesics; Humans; Pain; Quality of Life; Sevoflurane | 2021 |
The EEG signal: a window on the cortical brain activity.
Topics: Adult; Aging; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Cerebral Cortex; Child; | 2012 |
Trials
13 trials available for sevoflurane and Ache
| Article | Year |
|---|---|
Total Intravenous Anesthesia Versus Inhaled Sevoflurane in Obstructive Sleep Apnea Surgery: A Randomized Controlled Trial.
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intraveno | 2023 |
The effect of opioid-free anaesthesia on the quality of recovery after endoscopic sinus surgery: A multicentre randomised controlled trial.
Topics: Analgesics, Opioid; Anesthesia; Humans; Pain; Pain, Postoperative; Postoperative Nausea and Vomiting | 2023 |
Sucking lollipop after awakening from sevoflurane anesthesia reduces the degree of emergence agitation in children undergoing ambulatory surgery: A prospective randomized controlled trial.
Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhala | 2023 |
Comparison of blood pressure and pain rating index used for depth regulation of sevoflurane anaesthesia.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Blood Pressure; Humans; Methyl Ethers; Pain; Se | 2021 |
Comparison of the Analgesic Properties of Sevoflurane and Desflurane Using Surgical Pleth Index at Equi-Minimum Alveolar Concentration.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Arthroscopy; Brachial Plexus Block; Desflura | 2017 |
The effect of sevoflurane versus desflurane on postoperative catheter-related bladder discomfort in patients undergoing transurethral excision of a bladder tumour: a randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Desflurane; Female; Humans; Incidence; Isofluran | 2016 |
Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery.
Topics: Adult; Ambulatory Surgical Procedures; Female; Fentanyl; Humans; Male; Methyl Ethers; Nausea; Pain; | 2008 |
Low fresh gas flow balanced anesthesia versus target controlled intravenous infusion anesthesia in laparoscopic cholecystectomy: a cost-minimization analysis.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Chol | 2008 |
Sevoflurane for central catheter placement in neonatal intensive care: a randomized trial.
Topics: Anesthetics, Inhalation; Blood Glucose; Catheterization, Central Venous; Feasibility Studies; Female | 2010 |
A short period of inhalation induction with sevoflurane prevents rocuronium-induced withdrawal in children.
Topics: Androstanols; Anesthesia, Inhalation; Anesthetics, Inhalation; Blinking; Child; Child, Preschool; Fe | 2011 |
Sevoflurane to alleviate pain on propofol injection.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Fentanyl; Humans; Injections, Intr | 2011 |
Propofol and sevoflurane during epidural/general anesthesia: comparison of early recovery characteristics and pain relief.
Topics: Abdomen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia Recovery Period; | 2004 |
A comparison of the respiratory effects of sevoflurane and halothane in infants and young children.
Topics: Anesthetics, Inhalation; Child, Preschool; Extremities; Halothane; Humans; Infant; Infant, Newborn; | 1998 |
Other Studies
43 other studies available for sevoflurane and Ache
| Article | Year |
|---|---|
Cost-effectiveness analysis of domiciliary topical sevoflurane for painful leg ulcers.
Topics: Administration, Topical; Aged; Aged, 80 and over; Analgesics; Bayes Theorem; Cost-Benefit Analysis; | 2021 |
Comprehensive risk assessments and anesthetic management for children with osteogenesis imperfecta: A retrospective review of 252 orthopedic procedures over 5 years.
Topics: Anesthesia, Conduction; Anesthetics; Child; Hemorrhage; Humans; Orthopedic Procedures; Osteogenesis | 2022 |
Recovery Benefit With Total Intravenous Anesthesia in Patients Receiving Rhinoplasty.
Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Hum | 2023 |
Pain reduction of topical sevoflurane vs intravenous opioids in pressure ulcers.
Topics: Administration, Intravenous; Administration, Topical; Adult; Aged; Aged, 80 and over; Analgesics, Op | 2020 |
Correlation between pain rating index and end-tidal sevoflurane concentration during sevoflurane anesthesia.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Humans; Methyl Ethers; Pain; Partial Pressure; | 2021 |
5-HT1A Receptors Mediate Analgesia Induced by Emulsified Sevoflurane in Thermal Nociception but Have Little Effect on Chemical Nociception.
Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Femal | 2017 |
Efficacy and safety of topical sevoflurane in the treatment of chronic skin ulcers.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Anesthetics, Inhalation; Chronic Disease; Female | 2017 |
Healing of chronic venous ulcer with topical sevoflurane.
Topics: Administration, Topical; Aged; Aged, 80 and over; Chronic Disease; Female; Humans; Male; Methyl Ethe | 2017 |
Application of Topical Sevoflurane Before Cleaning Painful Skin Ulcers.
Topics: Administration, Topical; Humans; Pain; Sevoflurane; Skin Ulcer | 2018 |
Sevoflurane for Short Painful Procedures in the Neonatal Intensive Care Unit.
Topics: Anesthetics, Inhalation; Biopsy; Catheterization, Central Venous; Gestational Age; Humans; Infant; I | 2019 |
Analgesic effectiveness of topical sevoflurane to perform sharp debridement of painful wounds.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analgesics; Debridement; Female; Humans; Ma | 2019 |
Anesthesia for a child with Camurati-Engelmann disease.
Topics: Anesthesia, General; Anesthetics, Inhalation; Camurati-Engelmann Syndrome; Child; Colonoscopy; Human | 2013 |
Sedation for intra-articular corticosteroid injections in juvenile idiopathic arthritis: the views of patients and their parents.
Topics: Adolescent; Anesthetics, Inhalation; Arthritis, Juvenile; Child; Conscious Sedation; Data Collection | 2013 |
Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice.
Topics: Aging; Alzheimer Disease; Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Diseas | 2014 |
κ-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice.
Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Isoflurane; Lumbar Vertebrae; Methyl Eth | 2014 |
Relationship between gamma-hydroxybutyric acid receptors and the hypnotic and analgesic effects of emulsified inhalation anesthetics.
Topics: Analgesics; Anesthetics, Inhalation; Animals; Benzocycloheptenes; Enflurane; Female; Hot Temperature | 2014 |
Intrathecal L-arginine reduces the antinociception of sevoflurane in formalin-induced pain in rats.
Topics: Anesthetics, Inhalation; Animals; Arginine; Injections, Spinal; Methyl Ethers; Neurons; Nitric Oxide | 2015 |
Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex.
Topics: Anesthetics, Inhalation; Animals; Anxiety; Behavior, Animal; Extracellular Signal-Regulated MAP Kina | 2015 |
Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics.
Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane; Female; In | 2009 |
Functional connectivity and alterations in baseline brain state in humans.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Brain; Brain Mapping; Female; Humans; Image Processing, | 2010 |
Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Brain Ischemia; Cerebral Cortex; Coloring Agents | 2010 |
Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Anxiety; Consciousness Monitors; Cross-Section | 2012 |
Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Anxiety; Consciousness Monitors; Cross-Section | 2012 |
Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Anxiety; Consciousness Monitors; Cross-Section | 2012 |
Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Anxiety; Consciousness Monitors; Cross-Section | 2012 |
Effects of propofol, sevoflurane, remifentanil, and (S)-ketamine in subanesthetic concentrations on visceral and somatosensory pain-evoked potentials.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intraven | 2013 |
A new method of continuous maxillary nerve block with an indwelling catheter.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Lo | 2002 |
MAC reduction after intrathecal coadministration of GABA(A) agonist and glutamate antagonist in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Inhalation; Animals; Drug Synergism; Excitatory Amino Acid | 2003 |
The critical role of concentration for lidocaine block of peripheral nerve in vivo: studies of function and drug uptake in the rat.
Topics: Anesthetics, Inhalation; Anesthetics, Local; Animals; Behavior, Animal; Dose-Response Relationship, | 2003 |
Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia.
Topics: Adult; Aged; Anesthesia; Anesthetics, Inhalation; Electroencephalography; Female; Fentanyl; Humans; | 2004 |
Reversal of minimum alveolar concentrations of volatile anesthetics by chromosomal substitution.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Chromosomes; Gene Transfer Techniques; Haloth | 2004 |
Clinical actions of subarachnoid sevoflurane administration in vivo: a study in dogs.
Topics: Anesthesia, Spinal; Anesthetics, Inhalation; Animals; Conscious Sedation; Consciousness; Dogs; Dose- | 2005 |
Profound pain due to propofol injection triggered severe bronchospasm in a smoker--A case report.
Topics: Albuterol; Aminophylline; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Inflammatory Agent | 2006 |
Sevoflurane and analgesia.
Topics: Analgesia, Obstetrical; Anesthetics, Inhalation; Female; Humans; Methyl Ethers; Pain; Pregnancy; Sev | 2007 |
Strychnine-sensitive glycine receptors mediate the analgesic but not hypnotic effects of emulsified volatile anesthetics.
Topics: Analgesia; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane; | 2007 |
Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics.
Topics: Acetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inha | 2007 |
Concentration-effect relations, prediction probabilities (Pk), and signal-to-noise ratios of different electroencephalographic parameters during administration of desflurane, isoflurane, and sevoflurane in rats.
Topics: Animals; Brain; Cross-Over Studies; Desflurane; Electric Stimulation; Electroencephalography; Isoflu | 2008 |
Effects of pain stimulation on bispectral index, heart rate and blood pressure at different minimal alveolar concentration values of sevoflurane.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Blood Pressure; Dose-Response Relationship, Drug; Electr | 2008 |
Spontaneously breathing technique for opioid tolerance.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Inhalation; Anti-Inflammatory | 2008 |
Alterations in pain threshold and psychomotor response associated with subanaesthetic concentrations of inhalation anaesthetics in humans.
Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Halothane; Humans; Isoflurane; Male; | 1993 |
Acute pain and central nervous system arousal do not restore impaired hypoxic ventilatory response during sevoflurane sedation.
Topics: Acute Disease; Administration, Inhalation; Adult; Anesthetics, Inhalation; Arousal; Carbon Dioxide; | 1996 |
Sevoflurane suppresses behavioral response in the rat formalin test: combination with intrathecal lidocaine produced profound suppression of the response.
Topics: Anesthetics, Inhalation; Anesthetics, Local; Animals; Behavior, Animal; Drug Synergism; Formaldehyde | 1998 |
Magnitude of skin vasomotor reflex represents the intensity of nociception under general anesthesia.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Electric Stimulation; Humans; Laser-Doppler Flo | 1998 |
The combined effects of sevoflurane and remifentanil on central respiratory activity and nociceptive cardiovascular responses in anesthetized rabbits.
Topics: Action Potentials; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pre | 1999 |
Influence of low-dose anaesthetic agents on ventilatory control: where do we stand?
Topics: Anesthetics, Inhalation; Arousal; Depression, Chemical; Humans; Isoflurane; Methyl Ethers; Pain; Res | 1999 |
P2-purinergic receptor antagonists reduce the minimum alveolar concentration of inhaled volatile anesthetics.
Topics: Adenosine Triphosphate; Anesthesia; Anesthetics, Inhalation; Animals; Antineoplastic Agents; Brain; | 2000 |