rolipram and Pain
rolipram has been researched along with Pain in 6 studies
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Rolipram, a selective PDE IV inhibitor and theophylline a nonspecific PDE inhibitor exerted dose dependent analgesic and anti-inflammatory effect against acetic acid-induced writhing in mice and carrageenan-induced paw edema in rats, respectively." | 3.70 | Analgesic and anti-inflammatory effects of phosphodiesterase inhibitors. ( Jain, NK; Kulkarni, SK; Kumar, A, 2000) |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Blöcher, R | 1 |
| Wagner, KM | 1 |
| Gopireddy, RR | 1 |
| Harris, TR | 1 |
| Wu, H | 1 |
| Barnych, B | 1 |
| Hwang, SH | 1 |
| Xiang, YK | 1 |
| Proschak, E | 1 |
| Morisseau, C | 1 |
| Hammock, BD | 1 |
| Chłoń-Rzepa, G | 1 |
| Ślusarczyk, M | 1 |
| Jankowska, A | 1 |
| Gawalska, A | 1 |
| Bucki, A | 1 |
| Kołaczkowski, M | 1 |
| Świerczek, A | 1 |
| Pociecha, K | 1 |
| Wyska, E | 1 |
| Zygmunt, M | 1 |
| Kazek, G | 1 |
| Sałat, K | 1 |
| Pawłowski, M | 1 |
| Torres-López, JE | 1 |
| Argüelles, CF | 1 |
| Granados-Soto, V | 1 |
| Ouseph, AK | 1 |
| Khasar, SG | 1 |
| Levine, JD | 2 |
| Kumar, A | 1 |
| Jain, NK | 1 |
| Kulkarni, SK | 1 |
| Taiwo, YO | 1 |
| Heller, PH | 1 |
Other Studies
6 other studies available for rolipram and Pain
| Article | Year |
|---|---|
Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain.
Topics: Administration, Oral; Analgesics; Animals; Epoxide Hydrolases; HEK293 Cells; Humans; Inflammation; L | 2018 |
Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain.
Topics: Amides; Analgesics; Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phospho | 2018 |
Participation of peripheral and spinal phosphodiesterases 4 and 5 in inflammatory pain.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic Nucleotide | 2002 |
Multiple second messenger systems act sequentially to mediate rolipram-induced prolongation of prostaglandin E2-induced mechanical hyperalgesia in the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoquinolines; Animals; Calcium; Carrier Proteins; Cyclic | 1995 |
Analgesic and anti-inflammatory effects of phosphodiesterase inhibitors.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageen | 2000 |
Mediation of serotonin hyperalgesia by the cAMP second messenger system.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy- | 1992 |