riluzole and Autism
riluzole has been researched along with Autism in 4 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Riluzole add-on therapy shows several therapeutic outcomes, particularly for improving irritability, in children with autism." | 9.17 | Riluzole as an adjunctive therapy to risperidone for the treatment of irritability in children with autistic disorder: a double-blind, placebo-controlled, randomized trial. ( Akhondzadeh, S; Ashrafi, M; Farokhnia, M; Ghaleiha, A; Hassanzadeh, E; Modabbernia, A; Mohammadi, E; Mohammadi, MR; Yekehtaz, H, 2013) |
| "Riluzole add-on therapy shows several therapeutic outcomes, particularly for improving irritability, in children with autism." | 5.17 | Riluzole as an adjunctive therapy to risperidone for the treatment of irritability in children with autistic disorder: a double-blind, placebo-controlled, randomized trial. ( Akhondzadeh, S; Ashrafi, M; Farokhnia, M; Ghaleiha, A; Hassanzadeh, E; Modabbernia, A; Mohammadi, E; Mohammadi, MR; Yekehtaz, H, 2013) |
| " We evaluated the evidence from randomized controlled trials (RCTs) regarding the use of the glutamatergic drug riluzole in mental illnesses; and conducted preliminary meta-analyses of its effectiveness in treating obsessive-compulsive disorder (OCD) and depression." | 5.01 | Efficacy and tolerability of riluzole in psychiatric disorders: A systematic review and preliminary meta-analysis. ( Amelsvoort, TV; de Boer, JN; Hirdes, M; McAlonan, GM; Vingerhoets, C; Zinkstok, JR, 2019) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| de Boer, JN | 1 |
| Vingerhoets, C | 1 |
| Hirdes, M | 1 |
| McAlonan, GM | 1 |
| Amelsvoort, TV | 1 |
| Zinkstok, JR | 1 |
| Ghaleiha, A | 1 |
| Mohammadi, E | 1 |
| Mohammadi, MR | 1 |
| Farokhnia, M | 1 |
| Modabbernia, A | 1 |
| Yekehtaz, H | 1 |
| Ashrafi, M | 1 |
| Hassanzadeh, E | 1 |
| Akhondzadeh, S | 1 |
| Veenstra-VanderWeele, J | 1 |
| Wink, LK | 1 |
| Erickson, CA | 1 |
| Stigler, KA | 1 |
| McDougle, CJ | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dextromethorphan as an Augmentation Agent in Treatment-resistant Schizophrenia: A Randomized, Group Sequential Adaptive Design, Controlled Clinical Trial[NCT05944510] | Phase 4 | 72 participants (Anticipated) | Interventional | 2023-08-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
1 review available for riluzole and Autism
| Article | Year |
|---|---|
Efficacy and tolerability of riluzole in psychiatric disorders: A systematic review and preliminary meta-analysis.
Topics: Adult; Autistic Disorder; Depressive Disorder; Female; Humans; Male; Mental Disorders; Neuroprotecti | 2019 |
Trials
1 trial available for riluzole and Autism
| Article | Year |
|---|---|
Riluzole as an adjunctive therapy to risperidone for the treatment of irritability in children with autistic disorder: a double-blind, placebo-controlled, randomized trial.
Topics: Antipsychotic Agents; Appetite; Autistic Disorder; Child; Child, Preschool; Double-Blind Method; Dru | 2013 |
Other Studies
2 other studies available for riluzole and Autism
| Article | Year |
|---|---|
Increase in valproic acid levels during riluzole treatment in an adolescent with autism.
Topics: Adolescent; Autistic Disorder; Female; Humans; Riluzole; Valproic Acid | 2010 |
Riluzole in autistic disorder.
Topics: Adolescent; Adult; Autistic Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; E | 2011 |