pyrroles has been researched along with Sarcoma in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.56) | 18.7374 |
| 1990's | 1 (2.56) | 18.2507 |
| 2000's | 11 (28.21) | 29.6817 |
| 2010's | 25 (64.10) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, A; Hirbe, AC; Lee, SM; Manji, GA; Pellicciotta, I; Pradhan, J; Rabadan, R; Raufi, AG; Schwartz, GK; Van Tine, BA | 1 |
| Bhalla, AD; Bolshakov, S; Ingram, DR; Kivlin, CM; Landers, SM; Lazar, AJ; Ma, X; May, CD; Sannaa, GAA; Torres, KE; Wang, WL; Watson, KL | 1 |
| Chang, C; Chen, X; Jiang, H; Lou, D; Qin, Q; Wang, J; Zhang, W; Zhong, D; Zhou, A | 1 |
| Bauer, S; Blay, JY; Gelderblom, H; Guchelaar, HJ; Hogendoorn, PC; Hohenberger, P; Kerst, JM; Leahy, M; Marreaud, S; Ouali, M; Ray-Coquard, I; Rutkowski, P; Seddon, BM; Sleijfer, S; van der Straaten, RJ; Weitman, SD | 1 |
| Ferrari, S; Paioli, A; Palmerini, E | 1 |
| Achen, MG; Chander, S; Choong, PF; Desai, J; Ferris, N; Fox, S; Herschtal, A; Hicks, RJ; Khamly, KK; Lewin, J; Mitchell, C; Ngan, SY; Powell, GJ; Slavin, J; Stacker, SA; Te Marvelde, L; Thomas, DM; Toner, GC; Young, RJ | 1 |
| Ahmed, M; Coleman, CN; Curran, WJ; Dicker, AP; Finkelstein, SE; Houghton, P; Kirsch, DG; Machtay, M; Monjazeb, AM; Teicher, BA; Vikram, B; Wang, D; Wong, P; Xu-Welliver, M | 1 |
| Adenis, A; Bay, JO; Bertucci, F; Blay, JY; Bompas, E; Cassier, P; Chaigneau, L; Chevreau, C; Collard, O; Cropet, C; Cupissol, D; Duffaud, F; Eberst, L; Gentet, JC; Le Cesne, A; Marec-Berard, P; Pautier, P; Penel, N; Piperno-Neumann, S; Ray-Coquard, I; Thyss, A | 1 |
| Blay, JY; Cassier, P; Dufresne, A; Heudel, P; Pissaloux, D; Ray-Coquard, I; Wang, Q | 1 |
| Biasco, G; Chen, L; Demetri, GD; Fly, K; Fumagalli, E; Gelderblom, H; Hurwitz, HI; Kaiser, PE; Kang, YK; Lechuga, MJ; Matczak, E; Reichardt, P; Rosen, LS; Rutkowski, P; Schuette, J; Seddon, B; Williams, CC; Yalcin, S | 1 |
| Hohenberger, P; Jakob, J; Kasper, B; Ronellenfitsch, U; Simeonova, A; Wenz, F | 1 |
| Komarov, YI; Latipova, DH; Novik, AV; Protsenko, SA; Semenova, AI; Teletaeva, GM | 1 |
| Kato, S | 1 |
| Akiyama, R; Anderson, JL; Denny, CT; Federman, N; Park, A; Tap, WD | 1 |
| Hirschberger, J; Holtermann, N; Kiupel, M | 1 |
| Boichuk, S; Dunaev, P; Galembikova, A; Khaibullina, S; Khusnutdinov, R; Lombardi, V; Ramazanov, B; Zykova, S | 1 |
| Hohenberger, P; Jakob, J; Kasper, B; Rauch, G; Ronellenfitsch, U; Simeonova, A; Wenz, F | 1 |
| Akhurst, T; Bhuchar, G; Butrynski, JE; D'Adamo, DR; Demetri, GD; George, S; Harmon, DC; Keohan, ML; Maki, RG; Merriam, P; Morgan, J; O'Mara, MM; Schwartz, GK; Van den Abbeele, AD; Wagner, AJ; Yap, JT | 1 |
| Baek, KH; Dodd, RD; Dreyfuss, JM; Fisher, CJ; Jacks, T; Kirsch, DG; Lee, YJ; Mahmood, U; Nielsen, GP; Park, PJ; Rothrock, C; Ryeom, S; Stangenberg, L; Waterman, PR; Weissleder, R; Yoon, SS | 1 |
| Deville, JL; Duffaud, F; Huynh, T; Salas, S | 1 |
| Garralda Cabanas, E; Hitt, R; Homet Moreno, B | 1 |
| Barbaud, A; Cuny, JF; Granel-Brocard, F; Guyot-Caquelin, P; Marchal, A; Schmutz, JL; Spaeth, D; Trechot, P | 1 |
| Delank, S; Eich, H; Wendtner, CM | 1 |
| Agresta, S; Antonia, S; Calitri, CE; Chiappori, A; D'Amato, G; Dean, M; Garrett, C; Han, G; Mahmood, ST; Schell, MJ; Vigil, CE; Zhao, X | 1 |
| Ishida, H; Ito, H; Itoh, H; Tsuchiyama, K; Yokoyama, O | 1 |
| Bucci, F; Cassinelli, G; Cominetti, D; De Cesare, M; Di Francesco, AM; Lanzi, C; Meco, D; Orlandi, A; Passeri, D; Petrangolini, G; Pisano, C; Riccardi, R; Tortoreto, M; Zaffaroni, N; Zuco, V; Zunino, F | 1 |
| Bagot, M; Basset-Seguin, N; Battistella, M; Bouaziz, JD; Comte, C; Farges, C; Kerob, D; le Maignan, C; Lebbé, C; Madjessli, N; Pagès, C; Penot, P; Vilmer, C | 1 |
| Kummer, G; Schultheis, B; Strumberg, D | 1 |
| Hoekman, K; Kakkar, AK; Kostense, PJ; Kuenen, BC; Levi, M; Meijers, JC; Pinedo, HM; van Hinsbergh, VW | 1 |
| Baselga, J; Cavalli, F; Conte, PF; Deplanque, G; Harris, AL; Hoekman, K; Huisman, H; Kuenen, BC; Madhusudan, S; Pfanner, E; Scigalla, P; Seeber, S; Tabernero, J | 1 |
| von Mehren, M | 1 |
| Connors, S; Davis, DW; Demetri, GD; Desai, J; Fletcher, CD; Folkman, J; Goss, G; Harmon, D; Heymach, JV; Manola, J; McConkey, DJ; Quigley, T; Ryan, DP; Silverman, SG; Van den Abbeele, AD | 1 |
| Benini, S; Croci, S; García-Echeverría, C; Hofmann, F; Lollini, PL; Lukas, S; Manara, MC; Nicoletti, G; Perdichizzi, S; Picci, P; Scotlandi, K; Serra, M; Zambelli, D | 1 |
| Blay, JY; de Balincourt, C; di Paola, ED; Duffaud, F; Fowst, C; Hogendoorn, PC; Judson, I; Le Cesne, A; Leahy, M; Ray-Coquard, I; van Glabbeke, M; Verweij, J | 1 |
| Alberti, L; Blay, JY; Cassier, PA; Dufresne, A; Fayette, J; Ranchere, D; Ray-Coquard, I | 1 |
| Corless, CL; Heinrich, MC | 1 |
| Angelov, L; Guha, A; McMahon, G; Roncari, L; Salhia, B | 1 |
| Ishibashi, F; Iwao, M; Oda, T; Tanabe, S | 1 |
| Grasso, P; Hooson, J; Mattocks, AR | 1 |
10 review(s) available for pyrroles and Sarcoma
| Article | Year |
|---|---|
Emerging therapeutic targets for synovial sarcoma.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bevacizumab; Everolimus; Humans; Indazoles; Indoles; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Pyrimidines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Sarcoma, Synovial; Sirolimus; Sorafenib; Sulfonamides; Sunitinib; TOR Serine-Threonine Kinases | 2014 |
Combining targeted agents with modern radiotherapy in soft tissue sarcomas.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Cell Cycle; Cell Survival; Chemotherapy, Adjuvant; Cyclin-Dependent Kinase 4; Humans; Indazoles; Indoles; Ipilimumab; Molecular Targeted Therapy; Niacinamide; Nivolumab; Phenylurea Compounds; Proto-Oncogene Proteins c-mdm2; Pyrimidines; Pyrroles; Radiotherapy, Adjuvant; Sarcoma; Signal Transduction; Sorafenib; Sulfonamides; Sunitinib; Tumor Microenvironment | 2014 |
[Molecular biology of sarcoma and therapeutic choices].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Benzamides; Bone Neoplasms; Crizotinib; Denosumab; Dermatofibrosarcoma; Gastrointestinal Stromal Tumors; Gene Amplification; Gene Deletion; Giant Cell Tumor of Bone; Humans; Imatinib Mesylate; Indoles; Molecular Targeted Therapy; Phenylurea Compounds; Piperazines; Point Mutation; Prognosis; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sarcoma; Sarcoma, Ewing; Sunitinib; Synovitis, Pigmented Villonodular; Translocation, Genetic | 2015 |
[Molecular targeted drugs for soft tissue sarcoma and neuroendocrine tumor].
Topics: Antibodies, Monoclonal, Humanized; Benzamides; Denosumab; Drug Discovery; Everolimus; Gastrointestinal Neoplasms; Humans; Imatinib Mesylate; Indazoles; Indoles; Molecular Targeted Therapy; Neuroendocrine Tumors; Niacinamide; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sarcoma; Sirolimus; Sorafenib; Sulfonamides; Sunitinib | 2015 |
[Antiangionic drugs in soft tissue sarcoma].
Topics: Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Doxorubicin; Humans; Indazoles; Indoles; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Pyridines; Pyrimidines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Soft Tissue Neoplasms; Sorafenib; Sulfonamides; Sunitinib; Vascular Endothelial Growth Factor A | 2010 |
Tyrosine kinase inhibitors in treating soft tissue sarcomas: sunitinib in non-GIST sarcomas.
Topics: Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Indoles; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sarcoma; Sunitinib | 2010 |
[Multimodality therapy concepts for soft tissue sarcomas].
Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Combined Modality Therapy; Cross-Sectional Studies; Gastrointestinal Stromal Tumors; Humans; Hyperthermia, Induced; Imatinib Mesylate; Indoles; Neoadjuvant Therapy; Palliative Care; Piperazines; Prognosis; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Radiotherapy, Adjuvant; Sarcoma; Soft Tissue Neoplasms; Sunitinib | 2010 |
New therapeutic strategies for soft tissue sarcomas.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Clinical Trials as Topic; Dioxoles; Docetaxel; Epothilones; Guanidines; Humans; Indoles; Isoquinolines; Protein Kinase Inhibitors; Protein Kinases; Pyrazines; Pyrroles; Sarcoma; Sirolimus; Sunitinib; Taxoids; Tetrahydroisoquinolines; TOR Serine-Threonine Kinases; Trabectedin | 2003 |
Emerging drugs for the treatment of soft tissue sarcomas.
Topics: Antineoplastic Agents; Benzamides; Dacarbazine; Doxorubicin; Gastrointestinal Stromal Tumors; Humans; Ifosfamide; Imatinib Mesylate; Indoles; Piperazines; Pyrimidines; Pyrroles; Sarcoma; Sunitinib | 2007 |
Molecular pathobiology of gastrointestinal stromal sarcomas.
Topics: Benzamides; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Indoles; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sarcoma; Sunitinib | 2008 |
14 trial(s) available for pyrroles and Sarcoma
| Article | Year |
|---|---|
Phase I study of the safety, pharmacokinetics and antitumor activity of famitinib.
Topics: Adult; Aged; Angiogenesis Inhibitors; Biotransformation; Carcinoma, Renal Cell; China; Cohort Studies; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Hypertension; Incidence; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasms; Postprandial Period; Protein Kinase Inhibitors; Pyrroles; Receptor Protein-Tyrosine Kinases; Sarcoma; Young Adult | 2013 |
Brostallicin versus doxorubicin as first-line chemotherapy in patients with advanced or metastatic soft tissue sarcoma: an European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group randomised phase II and pharmacogeneti
Topics: Adult; Antibiotics, Antineoplastic; Bone Neoplasms; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Europe; Gene Frequency; Genotype; Glutathione Transferase; Guanidines; Humans; Isoenzymes; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Pharmacogenetics; Polymorphism, Genetic; Pyrroles; Sarcoma; Treatment Outcome | 2014 |
A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cohort Studies; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Humans; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prospective Studies; Pyrroles; Radiotherapy, Adjuvant; Sarcoma; Sunitinib | 2014 |
The off-label use of targeted therapies in sarcomas: the OUTC'S program.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Disease-Free Survival; Drug Delivery Systems; Female; Humans; Indoles; Male; Middle Aged; Niacinamide; Off-Label Use; Phenylurea Compounds; Pyrroles; Registries; Sarcoma; Sirolimus; Sorafenib; Sunitinib; Treatment Outcome; Young Adult | 2014 |
Clinical outcomes of patients with advanced gastrointestinal stromal tumors: safety and efficacy in a worldwide treatment-use trial of sunitinib.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Child; Diarrhea; Disease-Free Survival; Fatigue; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Pyrroles; Sarcoma; Sunitinib; Treatment Outcome; Young Adult | 2015 |
Combined radiation therapy and sunitinib for preoperative treatment of soft tissue sarcoma.
Topics: Adult; Aged; Angiogenesis Inhibitors; Chemoradiotherapy; Extremities; Female; Follow-Up Studies; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Preoperative Care; Prognosis; Prospective Studies; Pyrroles; Radiotherapy, Adjuvant; Retroperitoneal Neoplasms; Sarcoma; Sunitinib | 2015 |
The tyrosine kinase inhibitor toceranib in feline injection site sarcoma: efficacy and side effects.
Topics: Animals; Antineoplastic Agents; Cat Diseases; Cats; Female; Indoles; Injections; Male; Protein-Tyrosine Kinases; Pyrroles; Sarcoma; Soft Tissue Neoplasms | 2017 |
Combined sunitinib and radiation therapy for preoperative treatment of soft tissue sarcoma: results of a phase I trial of the German interdisciplinary sarcoma group (GISG-03).
Topics: Adult; Aged; Antineoplastic Agents; Chemoradiotherapy; Cohort Studies; Female; Follow-Up Studies; Humans; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Prognosis; Pyrroles; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Sarcoma; Sunitinib | 2016 |
Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Disease-Free Survival; Female; Humans; Indoles; Male; Middle Aged; Positron-Emission Tomography; Pyrroles; Sarcoma; Soft Tissue Neoplasms; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2009 |
Phase II study of sunitinib malate, a multitargeted tyrosine kinase inhibitor in patients with relapsed or refractory soft tissue sarcomas. Focus on three prevalent histologies: leiomyosarcoma, liposarcoma and malignant fibrous histiocytoma.
Topics: Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Histiocytoma, Malignant Fibrous; Humans; Indoles; Leiomyosarcoma; Liposarcoma; Male; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrroles; Recurrence; Retreatment; Sarcoma; Sunitinib; Survival Rate | 2011 |
Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients.
Topics: Angiogenesis Inhibitors; Blood Coagulation; Blood Platelets; Carcinoma, Renal Cell; Cell Division; Cell Membrane Permeability; Cell Movement; Drug Administration Schedule; Endothelium, Vascular; Fibrinolysis; Hemostasis; Humans; Indoles; Kidney Neoplasms; Melanoma; Neovascularization, Pathologic; Protein C; Proto-Oncogene Proteins; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Thrombin; Vascular Endothelial Growth Factor Receptor-1 | 2002 |
Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma.
Topics: Adult; Aged; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Indoles; Kidney Neoplasms; Male; Melanoma; Middle Aged; Neovascularization, Pathologic; Protein-Tyrosine Kinases; Pyrroles; Sarcoma; Skin Neoplasms; Treatment Outcome | 2003 |
Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas.
Topics: Adult; Aged; Angiogenesis Inhibitors; Disease-Free Survival; Female; Humans; Indoles; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Proto-Oncogene Proteins c-kit; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Safety; Sarcoma; Survival Rate; Vascular Endothelial Growth Factor A | 2004 |
Brostallicin, an agent with potential activity in metastatic soft tissue sarcoma: a phase II study from the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group.
Topics: Adult; Aged; Antineoplastic Agents; Disease Progression; Female; Gastrointestinal Stromal Tumors; Guanidines; Humans; Infusions, Intravenous; Male; Middle Aged; Pyrroles; Sarcoma; Soft Tissue Neoplasms; Survival Analysis; Treatment Outcome | 2007 |
15 other study(ies) available for pyrroles and Sarcoma
| Article | Year |
|---|---|
A Phase I Study of the Combination of Pexidartinib and Sirolimus to Target Tumor-Associated Macrophages in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors.
Topics: Aminopyridines; Humans; Male; Middle Aged; Neurofibrosarcoma; Pyrroles; Sarcoma; Sirolimus; Tumor-Associated Macrophages | 2021 |
Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; Female; Humans; Imidazoles; Mice; Mice, Hairless; Mice, SCID; Molecular Targeted Therapy; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Quinolines; Receptor, IGF Type 1; Receptors, Somatomedin; Sarcoma; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2017 |
[Systemic therapy of soft tissue sarcomas].
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dacarbazine; Deoxycytidine; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Ifosfamide; Indazoles; Indoles; Male; Molecular Targeted Therapy; Neoadjuvant Therapy; Niacinamide; Palliative Care; Phenylurea Compounds; Polyethylene Glycols; Pyrimidines; Pyrroles; Radiography; Sarcoma; Sorafenib; Sulfonamides; Sunitinib; Treatment Outcome | 2015 |
Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas.
Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Class I Phosphatidylinositol 3-Kinases; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Mechanistic Target of Rapamycin Complex 1; Morpholines; Multiprotein Complexes; Mutation; Osteosarcoma; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridones; Pyrimidines; Pyrimidinones; Pyrroles; Sarcoma; Signal Transduction; TOR Serine-Threonine Kinases | 2015 |
Ethyl-2-amino-pyrrole-3-carboxylates are novel potent anticancer agents that affect tubulin polymerization, induce G2/M cell-cycle arrest, and effectively inhibit soft tissue cancer cell growth in vitro.
Topics: Antineoplastic Agents; Bone Neoplasms; Carboxylic Acids; Cell Death; Cell Growth Processes; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Leiomyosarcoma; M Phase Cell Cycle Checkpoints; Osteosarcoma; Pyrroles; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Tubulin; Tubulin Modulators | 2016 |
Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Combined Modality Therapy; Drug Screening Assays, Antitumor; Indoles; Mice; Mice, Transgenic; Pyrroles; Random Allocation; Receptor, Platelet-Derived Growth Factor beta; Sarcoma; Sunitinib; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
[Leg ulcerations and sunitinib].
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Eruptions; Female; Humans; Indoles; Kidney Neoplasms; Leg Ulcer; Liver Neoplasms; Lung Neoplasms; Pyrroles; Risk Factors; Sarcoma; Sunitinib; Venous Thrombosis | 2010 |
[Advanced sarcomatoid renal cell carcinoma effectively treated with sunitinib: report of a case].
Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Pyrroles; Sarcoma; Sunitinib | 2011 |
The curative efficacy of namitecan (ST1968) in preclinical models of pediatric sarcoma is associated with antiangiogenic effects.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Camptothecin; Chemokine CCL2; Chemokine CXCL16; Chemokines, CXC; DNA Topoisomerases, Type I; Female; Fibroblast Growth Factor 2; Humans; Indoles; Mice; Mice, Nude; Pyrroles; Receptors, Scavenger; Rhabdomyosarcoma; Sarcoma; Sunitinib; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2012 |
Stabilization of multiple metastatic epithelioid sarcoma under treatment with sunitinib malate.
Topics: Adult; Amputation Stumps; Amputation, Surgical; Antineoplastic Agents; Axilla; Drug Administration Schedule; Forearm; Hand; Humans; Indoles; Male; Muscle Neoplasms; Neoplasm Recurrence, Local; Pyrroles; Sarcoma; Skin Neoplasms; Sunitinib; Treatment Outcome; Umbilicus | 2013 |
Sarcomatoid non-small cell lung cancer responding to sunitinib.
Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Follow-Up Studies; Humans; Indoles; Lung Neoplasms; Pyrroles; Sarcoma; Sunitinib; Treatment Outcome | 2013 |
Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Osteosarcoma; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Signal Transduction; Vincristine | 2005 |
Inhibition of angiogenesis by blocking activation of the vascular endothelial growth factor receptor 2 leads to decreased growth of neurogenic sarcomas.
Topics: Angiogenesis Inhibitors; Animals; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Indoles; Lymphokines; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neovascularization, Pathologic; Neurofibromatosis 1; Neurons; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Time Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Synthesis and structure-activity relationship study of lamellarin derivatives.
Topics: Alkaloids; Animals; Chlorocebus aethiops; Coumarins; Dogs; Drug Screening Assays, Antitumor; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Isoquinolines; Kidney; Mitomycin; Molecular Structure; Mollusca; Pyrroles; Rats; Sarcoma; Structure-Activity Relationship; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2002 |
An investigation into the carcinogenicity of monocrotaline pyrrole.
Topics: Carcinogens; Necrosis; Pyrroles; Pyrrolizidine Alkaloids; Sarcoma | 1973 |