pyrroles has been researched along with ADPKD in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Di Mise, A; Pellegrini, L; Torres, VE; Valenti, G; Wang, X; Ye, H | 1 |
| Abe, M; Akiya, Y; Baba, S; Fukuda, N; Kobayashi, H; Matsumoto, T; Tsunemi, A | 1 |
| Howell, BA; Pellegrini, L; Shoda, LKM; Woodhead, JL | 1 |
| Cudzich-Madry, A; Fragiadaki, M; Huang, Z; Patera, F | 1 |
| Chebib, FT; Constans, MM; Pellegrini, L; Torres, VE; Wang, X | 1 |
| Amura, CR; Barry, NP; Brodsky, KS; Doctor, RB; McWilliams, RR | 1 |
| Amura, CR; Brodsky, KS; Doctor, RB; Gattone, VH; Groff, R; Voelkel, NF | 1 |
7 other study(ies) available for pyrroles and ADPKD
| Article | Year |
|---|---|
Pre-clinical evaluation of dual targeting of the GPCRs CaSR and V2R as therapeutic strategy for autosomal dominant polycystic kidney disease.
Topics: Animals; Benzamides; Cyclic AMP; Drug Therapy, Combination; Female; Male; Mice; Mice, Inbred C57BL; Phenethylamines; Polycystic Kidney, Autosomal Dominant; Propylamines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Receptors, Vasopressin | 2021 |
Development of gene silencer pyrrole-imidazole polyamides targeting GSK3β for treatment of polycystic kidney diseases.
Topics: Animals; Colforsin; Cysts; Glycogen Synthase Kinase 3 beta; Imidazoles; Kidney; Mice; Nylons; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Pyrroles | 2023 |
Comparison of the Hepatotoxic Potential of Two Treatments for Autosomal-Dominant Polycystic Kidney DiseaseUsing Quantitative Systems Toxicology Modeling.
Topics: Benzamides; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Models, Theoretical; Polycystic Kidney, Autosomal Dominant; Pyrroles; Tolvaptan | 2020 |
Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis.
Topics: Animals; Cell Line; Cell Proliferation; Curcumin; Disease Models, Animal; Epithelial Cells; Humans; Janus Kinase 2; Kidney; Mice; Phosphorylation; Piperidines; Polycystic Kidney, Autosomal Dominant; Pyrimidines; Pyrroles; TRPP Cation Channels; Up-Regulation | 2019 |
Effect of a Vasopressin V2 Receptor Antagonist on Polycystic Kidney Disease Development in a Rat Model.
Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Benzamides; Creatinine; Cysts; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Kidney; Liver; Liver Diseases; Mutation; Organ Size; Polycystic Kidney, Autosomal Dominant; Pyrroles; Rats; Receptors, Cell Surface; Receptors, Vasopressin | 2019 |
Liver cyst cytokines promote endothelial cell proliferation and development.
Topics: Animals; Cell Proliferation; Cells, Cultured; Cyst Fluid; Cysts; Cytokines; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Liver Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Polycystic Kidney, Autosomal Dominant; Pyrroles; TRPP Cation Channels; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice.
Topics: Animals; Cell Proliferation; Cells, Cultured; Cyst Fluid; Cysts; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Indoles; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Polycystic Kidney, Autosomal Dominant; Protein Kinase Inhibitors; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Time Factors; TRPP Cation Channels; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2007 |