Page last updated: 2024-08-21

pyrazines and Sarcoma

pyrazines has been researched along with Sarcoma in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Gogal, RM; Laver, T; Lee, BM1
Algéo, MP; Chaire, V; Italiano, A; Laroche-Clary, A; Le Loarer, F; Malykh, A; Verbeke, S1
Driessen, C; Gogel, J; Hartmann, JT; Koscielniak, E; Kraus, M; Malenke, E; Müller, H; Ovaa, H; Overkleeft, H; Rückrich, T1
De Becker, A; De Raeve, H; Van Camp, B; Van Riet, I; Vanderkerken, K; Xu, S1
Birdsell, CA; Crosby, NA; Ernstoff, MS; Poklepovic, A; Ramakrishnan, V; Roberts, JD; Winning, M; Youseffian, L; Youssefian, LE1
von Mehren, M1
Antonescu, CR; Kraft, AS; Maki, RG; Scheu, K; Schwartz, GK; Wadler, S; Wright, JJ; Yamada, J1
Benjamin, RS; Burgess, MA; Gray, R; Jenkins, J; Papadopolous, NE; Patel, SR; Plager, C; Sidhu, G1

Reviews

1 review(s) available for pyrazines and Sarcoma

ArticleYear
New therapeutic strategies for soft tissue sarcomas.
    Current treatment options in oncology, 2003, Volume: 4, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Clinical Trials as Topic; Dioxoles; Docetaxel; Epothilones; Guanidines; Humans; Indoles; Isoquinolines; Protein Kinase Inhibitors; Protein Kinases; Pyrazines; Pyrroles; Sarcoma; Sirolimus; Sunitinib; Taxoids; Tetrahydroisoquinolines; TOR Serine-Threonine Kinases; Trabectedin

2003

Trials

3 trial(s) available for pyrazines and Sarcoma

ArticleYear
Phase I trial of bortezomib and dacarbazine in melanoma and soft tissue sarcoma.
    Investigational new drugs, 2013, Volume: 31, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Dacarbazine; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Medication Adherence; Melanoma; Middle Aged; Pyrazines; Radiography; Sarcoma; Treatment Outcome; Young Adult

2013
A multicenter Phase II study of bortezomib in recurrent or metastatic sarcomas.
    Cancer, 2005, Apr-01, Volume: 103, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Boronic Acids; Bortezomib; Drug Administration Schedule; Fatigue; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nervous System Diseases; Proteasome Inhibitors; Pyrazines; Sarcoma; Soft Tissue Neoplasms; Treatment Outcome

2005
Phase II study of CI-980 (NSC 635370) in patients with previously treated advanced soft-tissue sarcomas.
    Investigational new drugs, 1998, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carbamates; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neutropenia; Pyrazines; Pyridines; Sarcoma; Treatment Outcome

1998

Other Studies

4 other study(ies) available for pyrazines and Sarcoma

ArticleYear
Bortezomib inhibits the proteasome, leading to cell death via apoptosis in feline injection site sarcoma cells in vitro.
    American journal of veterinary research, 2022, May-08, Volume: 83, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cat Diseases; Cats; Cell Line, Tumor; Proteasome Endopeptidase Complex; Pyrazines; Sarcoma

2022
ATR Inhibition Broadly Sensitizes Soft-Tissue Sarcoma Cells to Chemotherapy Independent of Alternative Lengthening Telomere (ALT) Status.
    Scientific reports, 2020, 05-04, Volume: 10, Issue:1

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Cell Line, Tumor; DNA Damage; Female; Humans; Isoxazoles; Mice; Mice, Knockout; Neoplasm Proteins; Pyrazines; S Phase Cell Cycle Checkpoints; Sarcoma; Telomere Homeostasis; Xenograft Model Antitumor Assays

2020
Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Boronic Acids; Bortezomib; Cell Death; Cell Line, Tumor; Drug Screening Assays, Antitumor; Endoplasmic Reticulum; G2 Phase; Humans; Neoplasm Proteins; Proteasome Inhibitors; Protein Biosynthesis; Protein Folding; Protein Subunits; Pyrazines; Ritonavir; Sarcoma

2008
In vitro expanded bone marrow-derived murine (C57Bl/KaLwRij) mesenchymal stem cells can acquire CD34 expression and induce sarcoma formation in vivo.
    Biochemical and biophysical research communications, 2012, Aug-03, Volume: 424, Issue:3

    Topics: Animals; Antigens, CD34; Bone Marrow Cells; Boronic Acids; Bortezomib; Cell Transformation, Neoplastic; Female; Hydroxamic Acids; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Pyrazines; Receptors, Notch; Sarcoma; Vorinostat; Wnt Proteins

2012