pyrazines has been researched along with Anxiety in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, S; Chew, LA; Jiang, Y; Jin, Y; Khanna, R; Ruan, Y; Wen, C; Xu, Z; Yu, J; Zhong, K | 1 |
| Arihara, K; Ohata, M; Yada, Y; Yokoyama, I; Zhou, L | 1 |
| de Andrade, TGCS; Hernandes, PM; Sant'Ana, AB; Vicente, MA; Vilela-Costa, HH; Zangrossi, H | 1 |
| Vicente, MA; Zangrossi, H | 1 |
| Bègue, L; Bell, R; Duke, AA; Gilmore, PE; Page, D | 1 |
| Bates, BS; Blobaum, AL; Byers, FW; Conn, PJ; Daniels, JS; Emmitte, KA; Felts, AS; Jones, CK; Lawson, KP; Lindsley, CW; Morrison, RD; Niswender, CM; Rodriguez, AL; Venable, DF | 1 |
| Der-Ghazarian, T; Neisewander, JL; Pentkowski, NS; Pockros-Burgess, LA | 1 |
| Deeva, OA; Gudasheva, TA; Mokrov, GV; Seredenin, SB; Yarkov, SA; Yarkova, MA | 1 |
| Fleshner, M; Greenwood, BN; Strong, PV | 1 |
| Eller, M; Foreman, MM; Hanania, T | 1 |
| Gomes, KS; Nunes-De-Souza, RL | 1 |
| Buell, DR; Dine, J; Eder, M; Herrmann, L; Holsboer, F; Ionescu, IA; Landgraf, R; Schmidt, U; Yen, YC | 1 |
| Combs, AP; Dzierba, CD; Gilligan, PJ; Kasireddy-Polam, P; Lelas, S; Li, YW; McElroy, JF; Molski, TF; Peng, Y; Rafalski, M; Takvorian, AG; Taub, RA; Trainor, GL; Wong, H; Zaczek, RC; Zhang, G | 1 |
| Davis, M; Donovan, JL; Hamdy, FC; Lane, JA; Metcalfe, C; Mills, N; Neal, DE; Peters, TJ; Ronsmans, C; Sterne, JA | 1 |
| Amstislavskaya, TG; Bulygina, VV; Kuznetsova, EG; Popova, NK; Tibeikina, MA | 1 |
| Caignard, DH; Delagrange, P; Guardiola-Lemaitre, B; Hamon, M; Lancelot, JC; Misslin, R; Pfeiffer, B; Prunier, H; Rault, S; Renard, P; Robba, M | 1 |
| Delagrange, P; Misslin, R; Pfeiffer, B; Rault, S; Renard, P; Seale, TW | 1 |
| Al-Shaltchi, B; Brändli, A; Fleischhauer, J | 1 |
18 other study(ies) available for pyrazines and Anxiety
| Article | Year |
|---|---|
Tetramethylpyrazine Reduces Epileptogenesis Progression in Electrical Kindling Models by Modulating Hippocampal Excitatory Neurotransmission.
Topics: Animals; Anticonvulsants; Anxiety; CA1 Region, Hippocampal; Calcium Channel Blockers; Calcium Channels; Convulsants; Disease Progression; Electric Stimulation; Electroshock; Epilepsy, Complex Partial; Excitatory Postsynaptic Potentials; Exploratory Behavior; Ion Transport; Kindling, Neurologic; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Pentylenetetrazole; Pyrazines; Recognition, Psychology; Seizures; Sodium Channels | 2019 |
2,3-Dimethylpyrazine (3DP) and 2,5-dimethyl-4-hydroxy-3(2
Topics: Anger; Anxiety; Autonomic Nervous System; Central Nervous System; Female; Food; Furans; Glucose; Glycine; Humans; Maillard Reaction; Male; Odorants; Pyrazines; Young Adult | 2020 |
Role of 5-HT2C receptors of the dorsal hippocampus in the modulation of anxiety- and panic-related defensive responses in rats.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Ethylamines; Hippocampus; Imipramine; Indoles; Male; Maze Learning; Microinjections; Panic; Piperazines; Punishment; Pyrazines; Rats; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists | 2019 |
Involvement of 5-HT2C and 5-HT1A receptors of the basolateral nucleus of the amygdala in the anxiolytic effect of chronic antidepressant treatment.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Avoidance Learning; Exploratory Behavior; Fluoxetine; Imipramine; Male; Maze Learning; Panic; Piperazines; Pyrazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists | 2014 |
Anxiolytic-like effects observed in rats exposed to the elevated zero-maze following treatment with 5-HT2/5-HT3/5-HT4 ligands.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Male; Maze Learning; Oxazines; Piperidines; Propane; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides | 2014 |
Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety.
Topics: Allosteric Site; Animals; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Humans; Male; Mice; Molecular Structure; Picolinic Acids; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Structure-Activity Relationship | 2014 |
Effects of the 5-HT2C receptor agonist CP809101 in the amygdala on reinstatement of cocaine-seeking behavior and anxiety-like behavior.
Topics: Aminopyridines; Amygdala; Animals; Anxiety; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Indoles; Male; Maze Learning; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Serotonin 5-HT2 Receptor Agonists | 2014 |
Design, synthesis and anxiolytic-like activity of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides.
Topics: Amides; Animals; Anti-Anxiety Agents; Anxiety; Binding Sites; Diazepam; Dose-Response Relationship, Drug; Drug Design; Gene Expression; Isoquinolines; Ligands; Male; Maze Learning; Mice; Mice, Inbred BALB C; Motor Activity; Protein Binding; Pyrazines; Receptors, GABA; Structure-Activity Relationship | 2015 |
The effects of the selective 5-HT(2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats.
Topics: Aminopyridines; Animals; Anxiety; Escape Reaction; Freezing Reaction, Cataleptic; Helplessness, Learned; Indoles; Injections, Intraperitoneal; Male; Piperazines; Pyrazines; Rats; Rats, Inbred F344; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological | 2009 |
Anxiolytic effects of lamotrigine and JZP-4 in the elevated plus maze and in the four plate conflict test.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Lamotrigine; Male; Maze Learning; Mice; Punishment; Pyrazines; Triazines | 2009 |
Implication of the 5-HT2A and 5-HT2C (but not 5HT1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Microinjections; Motor Activity; Periaqueductal Gray; Pyrazines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reproducibility of Results; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents | 2009 |
Intranasally administered neuropeptide S (NPS) exerts anxiolytic effects following internalization into NPS receptor-expressing neurons.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; CA1 Region, Hippocampal; Carbocyanines; Cell Line, Transformed; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Humans; In Vitro Techniques; Intravitreal Injections; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurofilament Proteins; Neurons; Neuropeptides; Oxazolidinones; Protein Transport; Pyrazines; Receptors, AMPA; Receptors, Neuropeptide; Rhodamines; RNA, Messenger; Synapsins; Transfection | 2012 |
Synthesis, structure-activity relationships, and in vivo properties of 3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-ones as corticotropin-releasing factor-1 receptor antagonists.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding, Competitive; Dogs; Frontal Lobe; Half-Life; In Vitro Techniques; Male; Pyrazines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Corticotropin-Releasing Hormone; Structure-Activity Relationship | 2004 |
A comparison of socio-demographic and psychological factors between patients consenting to randomisation and those selecting treatment (the ProtecT study).
Topics: Aged; Anxiety; Depression; Follow-Up Studies; Humans; Hydrazines; Male; Middle Aged; Patient Satisfaction; Patient Selection; Prostatic Neoplasms; Pyrazines; Quinolines; Randomized Controlled Trials as Topic; Socioeconomic Factors | 2006 |
Effect of 5HT2C-receptor agonist MK-212 on blood corticosterone level and behavior in mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression, Chemical; Male; Mice; Mice, Inbred CBA; Motor Activity; Pyrazines; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists | 2006 |
Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cattle; Cell Membrane; Corpus Striatum; Darkness; Frontal Lobe; Guanidine; Guanidines; Hippocampus; Light; Male; Molecular Structure; Pyrazines; Pyridines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Structure-Activity Relationship; Swine | 1997 |
Effects of S-21007, a potent 5-HT3 partial agonist, in mouse anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Male; Mice; Mice, Inbred BALB C; Piperazines; Pyrazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists | 1999 |
[Report on a preliminary open clinical study of mianserin (GB 94), a tetracyclic antidepressant].
Topics: Adult; Aged; Animals; Antidepressive Agents; Anxiety; Azepines; Bipolar Disorder; Conflict, Psychological; Depression; Depressive Disorder, Major; Dopamine Antagonists; Electroencephalography; Feeding and Eating Disorders; Female; Humans; Mental Fatigue; Mice; Middle Aged; Pyrazines; Rats; Serologic Tests; Sleep Wake Disorders | 1973 |