Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and ATLL

pyrazines has been researched along with ATLL in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (75.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambinder, RF; Forde, PM; Gladstone, DE; Hourigan, CS1
Bamford, RN; Conlon, KC; Ju, W; Maeda, M; Nakagawa, M; Petrus, MN; Waldmann, TA; Yu, P; Zhang, M1
Ishitsuka, K; Katsuya, H; Kunami, N; Nogami, R; Tamura, K1
Ding, J; Iida, S; Inagaki, A; Ishida, T; Ito, A; Komatsu, H; Kusumoto, S; Ri, M; Ueda, R; Utsunomiya, A; Yano, H1
Brady, JN; Dohoney, K; Janik, JE; Lee, MJ; Morris, JC; O'Mahony, D; Pise-Masison, CA; Radonovich, M; Trepel, J; Waldmann, TA1
Chen, Z; Gong, S; Lü, S; Wang, J; Xu, X; Yang, J; Zhou, H1
Koya, Y; Matsuoka, M; Nosaka, K; Satou, Y; Toyokuni, S; Yasunaga, JI1
Hatake, K; Mishima, Y; Terui, Y1
Matsuoka, M; Satou, Y1
Arnulf, B; Bazarbachi, A; Bex, F; Dbaibo, G; de Thé, H; El-Sabban, ME; Hermine, O; Karam, JA; Kfoury, Y; Lepelletier, Y; Nasr, R1
Utsunomya, A1
Tan, C; Waldmann, TA1

Reviews

3 review(s) available for pyrazines and ATLL

ArticleYear
[Proteasome inhibitors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:7

    Topics: Boronic Acids; Bortezomib; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cysteine Endopeptidases; Humans; Kidney Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Multienzyme Complexes; Multiple Myeloma; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines

2004
[Proteasome inhibitor, bortezomib (Vercade), potently inhibits the growth of adult T-cell leukemia cells].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62, Issue:7

    Topics: Adult; Antineoplastic Agents; Boronic Acids; Bortezomib; Cysteine Endopeptidases; Humans; Leukemia-Lymphoma, Adult T-Cell; Multienzyme Complexes; Proteasome Endopeptidase Complex; Pyrazines

2004
[Clinical and hematological characteristics of adult T-cell leukemia/lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2006, Volume: 47, Issue:12

    Topics: Benzamides; Boronic Acids; Bortezomib; Carrier State; Cyclohexanones; HIV Protease Inhibitors; Human T-lymphotropic virus 1; Humans; Infectious Disease Transmission, Vertical; Leukemia-Lymphoma, Adult T-Cell; NF-kappa B; Protease Inhibitors; Pyrazines; Ritonavir; Stem Cell Transplantation; Transplantation, Homologous

2006

Other Studies

9 other study(ies) available for pyrazines and ATLL

ArticleYear
Bortezomib salvage therapy in refractory acute adult T-cell leukemia/lymphoma.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:11

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Humans; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Pyrazines; Salvage Therapy; Treatment Outcome

2013
Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model.
    Leukemia, 2015, Volume: 29, Issue:3

    Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents; Benzodiazepinones; beta 2-Microglobulin; Biomarkers, Tumor; Boronic Acids; Bortezomib; Depsipeptides; Disease Models, Animal; Drug Therapy, Combination; Gene Expression Regulation, Leukemic; Humans; Interleukin-2 Receptor alpha Subunit; Leukemia-Lymphoma, Adult T-Cell; Mice; Mice, Inbred NOD; Mice, SCID; NF-kappa B; Pyrazines; Receptor, Notch1; Signal Transduction; Tumor Burden

2015
Promise of combining a Bcl-2 family inhibitor with bortezomib or SAHA for adult T-cell leukemia/lymphoma.
    Anticancer research, 2014, Volume: 34, Issue:10

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Biphenyl Compounds; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Leukemia-Lymphoma, Adult T-Cell; Nitrophenols; Piperazines; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Sulfonamides; Vorinostat

2014
Bortezomib-induced apoptosis in mature T-cell lymphoma cells partially depends on upregulation of Noxa and functional repression of Mcl-1.
    Cancer science, 2009, Volume: 100, Issue:2

    Topics: Adult; Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Proliferation; Humans; Immunoprecipitation; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, T-Cell, Cutaneous; Membrane Potential, Mitochondrial; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation

2009
Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability.
    Blood, 2009, Apr-23, Volume: 113, Issue:17

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Boronic Acids; Bortezomib; CD4-Positive T-Lymphocytes; Cell Survival; Daclizumab; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin G; Inhibitor of Apoptosis Proteins; Leukemia-Lymphoma, Adult T-Cell; Male; Microtubule-Associated Proteins; Middle Aged; Pyrazines; RNA Interference; Survivin; Transcription Factor 4; Transcription Factors; Tumor Cells, Cultured

2009
Different mutants of PSMB5 confer varying bortezomib resistance in T lymphoblastic lymphoma/leukemia cells derived from the Jurkat cell line.
    Experimental hematology, 2009, Volume: 37, Issue:7

    Topics: Antineoplastic Agents; Base Sequence; Boronic Acids; Bortezomib; DNA Primers; Drug Resistance, Neoplasm; Humans; Jurkat Cells; Leukemia-Lymphoma, Adult T-Cell; Mutation; Proteasome Endopeptidase Complex; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction

2009
Proteasome inhibitor, bortezomib, potently inhibits the growth of adult T-cell leukemia cells both in vivo and in vitro.
    Leukemia, 2004, Volume: 18, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Division; Cell Line, Transformed; Cell Line, Tumor; Cysteine Endopeptidases; HTLV-I Infections; Humans; Leukemia-Lymphoma, Adult T-Cell; Mice; Mice, SCID; Multienzyme Complexes; Neoplasm Transplantation; NF-kappa B; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Transplantation, Heterologous

2004
Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma.
    Oncogene, 2005, Jan-13, Volume: 24, Issue:3

    Topics: Adult; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Ceramides; Humans; Jurkat Cells; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, T-Cell; Protease Inhibitors; Proteasome Inhibitors; Pyrazines

2005
Proteasome inhibitor PS-341, a potential therapeutic agent for adult T-cell leukemia.
    Cancer research, 2002, Feb-15, Volume: 62, Issue:4

    Topics: Adult; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cysteine Endopeptidases; Daclizumab; DNA-Binding Proteins; DNA, Neoplasm; Drug Synergism; Humans; I-kappa B Proteins; Immunoglobulin G; Leukemia-Lymphoma, Adult T-Cell; Mice; Mice, Inbred NOD; Mice, SCID; Monocytes; Multienzyme Complexes; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Receptors, IgG

2002