purine and Gout
purine has been researched along with Gout in 51 studies
1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.
Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Recently it has been identified that hypertension are frequently associated with myogenic hyperuricemia converted from overproduced hypoxanthine in the skeletal muscles." | 8.84 | [Idiopathic hyperuricemia with overproduction of uric acid]. ( Hisatome, I; Igawa, O; Mizuta, E, 2008) |
| "Patients with system lupus erythematosus, rheumatic arthritis, chronic active hepatitis and gout were found to have considerable hyperuricemia and be decreased in aminoacides content, which are the predecessors of purine." | 7.73 | [Hyperuricemia and disorders in content of amino acids-purine precursors in patients with autoimmune diseases and gout]. ( Anan'eva, MN; Dubiaga, VV; Nikolenko, IuI; Nikolenko, VIu; Shchukin, IN; Siniachenko, OV, 2005) |
| "Various purine-rich foods and high protein intake have long been thought to be risk factors for gout." | 7.72 | Purine-rich foods, dairy and protein intake, and the risk of gout in men. ( Atkinson, K; Choi, HK; Curhan, G; Karlson, EW; Willett, W, 2004) |
| "Ten women with crystal-proved primary gout and normal serum creatinine levels (below 116 mmol/L) were studied while they were on a purine-restricted diet and taking no medications known to influence uric acid metabolism." | 7.69 | Purine metabolism in women with primary gout. ( de Miguel, E; Gil, AA; Mateos, FA; Miranda, ME; Pérez de Ayala, C; Puig, JG; Torres, RJ, 1994) |
| " Recently it has been identified that hypertension are frequently associated with myogenic hyperuricemia converted from overproduced hypoxanthine in the skeletal muscles." | 4.84 | [Idiopathic hyperuricemia with overproduction of uric acid]. ( Hisatome, I; Igawa, O; Mizuta, E, 2008) |
| "Low-purine food is not only the focus of gout patients, but also the focus of contemporary green diet development." | 3.96 | Effect of allicin and its mechanism of action in purine removal in turbot. ( Li, J; Li, Q; Li, T; Ren, L; Song, M; Wang, D, 2020) |
| "The purine contents of animal foods are becoming widely concerned because excess intake of purine increases the risk of hyperuricemia and gout." | 3.88 | Effects of breeds, tissues and genders on purine contents in pork and the relationships between purine content and other meat quality traits. ( Huang, L; Huang, Y; Ji, J; Ma, J; Xiao, S; Zheng, M, 2018) |
| "The purine contents of alcoholic beverages were determined in order to utilize them in the dietary care of gout and hyperuricemia." | 3.75 | Determination of purine contents of alcoholic beverages using high performance liquid chromatography. ( Fujimori, S; Kaneko, K; Yamanobe, T, 2009) |
| "Patients with system lupus erythematosus, rheumatic arthritis, chronic active hepatitis and gout were found to have considerable hyperuricemia and be decreased in aminoacides content, which are the predecessors of purine." | 3.73 | [Hyperuricemia and disorders in content of amino acids-purine precursors in patients with autoimmune diseases and gout]. ( Anan'eva, MN; Dubiaga, VV; Nikolenko, IuI; Nikolenko, VIu; Shchukin, IN; Siniachenko, OV, 2005) |
| "Various purine-rich foods and high protein intake have long been thought to be risk factors for gout." | 3.72 | Purine-rich foods, dairy and protein intake, and the risk of gout in men. ( Atkinson, K; Choi, HK; Curhan, G; Karlson, EW; Willett, W, 2004) |
| "Ten women with crystal-proved primary gout and normal serum creatinine levels (below 116 mmol/L) were studied while they were on a purine-restricted diet and taking no medications known to influence uric acid metabolism." | 3.69 | Purine metabolism in women with primary gout. ( de Miguel, E; Gil, AA; Mateos, FA; Miranda, ME; Pérez de Ayala, C; Puig, JG; Torres, RJ, 1994) |
| "The characteristic phenomena of acute gouty arthritis are acute arthritis in a middle-aged male, associated with serum uric acid above 6 mg." | 3.63 | Diagnosis and treatment of gouty arthritis. ( TALBOTT, JH, 1953) |
| "Gout is among the most common causes of acute monoarticular arthritis." | 2.43 | Purine metabolism and hyperuricemic states. 'The point of view of the rheumatologist'. ( Peronato, G, 2005) |
| "Gout is the typical feature of GAstrV infection in goslings." | 1.56 | Goose astrovirus infection affects uric acid production and excretion in goslings. ( Bao, E; Lv, Y; Wu, W; Xu, R, 2020) |
Research
Studies (51)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (50.98) | 18.7374 |
| 1990's | 4 (7.84) | 18.2507 |
| 2000's | 13 (25.49) | 29.6817 |
| 2010's | 2 (3.92) | 24.3611 |
| 2020's | 6 (11.76) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fukuuchi, T | 2 |
| Itahashi, I | 1 |
| Takayanagi, F | 2 |
| Yamaoka, N | 2 |
| Kaneko, K | 3 |
| Sabolová, M | 1 |
| Kulma, M | 1 |
| Petříčková, D | 1 |
| Kletečková, K | 1 |
| Kouřimská, L | 1 |
| Jia, Q | 1 |
| Yang, Z | 1 |
| Wang, Q | 1 |
| Yang, H | 1 |
| Tang, X | 1 |
| Zhang, H | 1 |
| Cao, L | 1 |
| Zhang, G | 2 |
| Wu, W | 1 |
| Xu, R | 1 |
| Lv, Y | 1 |
| Bao, E | 1 |
| Yasuda, M | 1 |
| Mawatari, KI | 1 |
| Fujimori, S | 2 |
| Li, T | 1 |
| Ren, L | 1 |
| Wang, D | 2 |
| Song, M | 1 |
| Li, Q | 1 |
| Li, J | 1 |
| Zheng, M | 1 |
| Huang, Y | 1 |
| Ji, J | 1 |
| Xiao, S | 1 |
| Ma, J | 1 |
| Huang, L | 1 |
| Rong, S | 1 |
| Zou, L | 1 |
| Zhang, Y | 1 |
| Li, X | 1 |
| Li, M | 1 |
| Yang, F | 1 |
| Li, C | 1 |
| He, Y | 1 |
| Guan, H | 1 |
| Guo, Y | 1 |
| Cui, X | 1 |
| Ye, H | 1 |
| Liu, F | 1 |
| Pan, H | 1 |
| Yang, Y | 1 |
| Yamanobe, T | 1 |
| Hayman, S | 1 |
| Marcason, W | 1 |
| Yamamoto, T | 2 |
| Iwatani, M | 1 |
| Morisaki, T | 1 |
| GUTMAN, AB | 3 |
| YU, TF | 3 |
| TALBOTT, JH | 2 |
| WEISSMANN, B | 2 |
| WYNGAARDEN, JB | 2 |
| LUCCHELLI, PE | 1 |
| CROSTI, PF | 1 |
| BEGUIRISTAIN, MA | 1 |
| GARDA, EA | 1 |
| BISHOP, C | 1 |
| RANKINE, DM | 1 |
| HITCHINGS, GH | 1 |
| FRANCOMANERA, R | 1 |
| GASPARDY, G | 1 |
| SCHULHOF, O | 1 |
| VIDA, M | 1 |
| RIVERA, JV | 1 |
| DELBARRE, F | 2 |
| ROBECCHI, A | 1 |
| HALL, AP | 1 |
| HOLLOWAY, VP | 1 |
| SCOTT, JT | 1 |
| GALMICHE, P | 1 |
| ALVSAKER, JO | 1 |
| AUSCHER, C | 1 |
| LABROUSSE, C | 1 |
| GERYA, DE | 1 |
| KLINENBERG, JR | 2 |
| GOLDFINGER, SE | 1 |
| SEEGMILLER, JE | 2 |
| GOLDFINGER, S | 1 |
| SEGAL, S | 1 |
| BRAMIGK, F | 1 |
| Johnson, RJ | 1 |
| Rideout, BA | 1 |
| Choi, HK | 2 |
| Atkinson, K | 1 |
| Karlson, EW | 1 |
| Willett, W | 1 |
| Curhan, G | 1 |
| Peronato, G | 1 |
| Nikolenko, IuI | 1 |
| Siniachenko, OV | 1 |
| Anan'eva, MN | 1 |
| Nikolenko, VIu | 1 |
| Dubiaga, VV | 1 |
| Shchukin, IN | 1 |
| Mount, DB | 1 |
| Reginato, AM | 1 |
| Taniguchi, A | 1 |
| Kamatani, N | 1 |
| Mizuta, E | 1 |
| Igawa, O | 1 |
| Hisatome, I | 1 |
| Wisner, DE | 1 |
| Simkin, PA | 1 |
| Gutensohn, W | 1 |
| Nuki, G | 1 |
| MacDermot, KD | 1 |
| Allsop, J | 1 |
| Watts, RW | 1 |
| Puig, JG | 1 |
| Mateos, FA | 1 |
| Miranda, ME | 1 |
| Torres, RJ | 1 |
| de Miguel, E | 1 |
| Pérez de Ayala, C | 1 |
| Gil, AA | 1 |
| Higashino, K | 1 |
| Moriwaki, Y | 1 |
| Curto, R | 1 |
| Voit, EO | 1 |
| Cascante, M | 1 |
| Nishioka, K | 1 |
| Kummer, H | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dietary Interventions Evaluating Transport of Uric Acid Across the Tubules[NCT00474396] | 59 participants (Actual) | Interventional | 2005-04-30 | Completed | |||
| A Three Arms, Randomized, Double-blind Controlled Trial of the Efficacy of Amway Uric Acid Lowering Product on Hyperuricemia[NCT06084585] | 180 participants (Anticipated) | Interventional | 2023-10-23 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
12 reviews available for purine and Gout
| Article | Year |
|---|---|
[Effect of foods on serum uric acid level].
Topics: Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Drinking; Food; Food Analysis; Gout; Hu | 2003 |
[Effect of ethanol on uric acid level].
Topics: Acetaldehyde; Animals; Erythrocytes; Ethanol; Gout; Humans; Hyperuricemia; Purines; Pyrazinamide; Ur | 2003 |
[Diet therapy for management of hyperuricemia and gout].
Topics: Adult; Alcoholic Beverages; Diet, Reducing; Gout; Humans; Hyperuricemia; Male; Obesity; Purines; Tem | 2003 |
[Animal models for abnormal purine metabolism].
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; AMP Deaminase; Animals; Disease Models, Anim | 2003 |
[DISEASES OF THE METABOLISM OF PURINES AND PYRIMIDINES].
Topics: Gout; Humans; Metabolic Diseases; Orotic Acid; Purines; Pyrimidines; Uric Acid; Urine; Xanthines | 1963 |
Purine metabolism and hyperuricemic states. 'The point of view of the rheumatologist'.
Topics: Gout; Humans; Hyperuricemia; Purines | 2005 |
Pathogenesis of gout.
Topics: Cardiovascular Diseases; Crystallization; Diet; Gout; Humans; Hyperuricemia; Inflammation; Insulin R | 2005 |
[Genetic testing and gene-based testing for hyperuricemia and gout].
Topics: Carrier Proteins; Genetic Diseases, Inborn; Gout; Humans; Hyperuricemia; Hypoxanthine Phosphoribosyl | 2005 |
[Idiopathic hyperuricemia with overproduction of uric acid].
Topics: Antihypertensive Agents; Gout; Humans; Hypertension; Hyperuricemia; Hypoxanthine; Muscle, Skeletal; | 2008 |
Human purine metabolism: some recent advances and relationships with immunodeficiency.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Glycogen Storage Disease Type I; Gout; Human | 1983 |
[Pharmacological agents affecting uric acid metabolism].
Topics: Allopurinol; Diuretics; Fructose; Gout; Gout Suppressants; Humans; Inosine; Kidney Diseases; Niacin; | 1996 |
[New concept of the pathogenesis of gout and hyperuricemia].
Topics: Energy Metabolism; Gout; Purines; Uric Acid | 1991 |
Other Studies
39 other studies available for purine and Gout
| Article | Year |
|---|---|
Determination of total purine and free purine content in milk, soymilk, and enteral nutritional supplements to assist nutritional therapy for hyperuricemia and gout.
Topics: Aged; Animals; Gout; Humans; Hyperuricemia; Milk; Purines; Uric Acid | 2022 |
Changes in purine and uric acid content in edible insects during culinary processing.
Topics: Animals; Edible Insects; Gout; Gryllidae; Humans; Insecta; Purines; Uric Acid; Xanthine | 2023 |
A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.
Topics: Animals; Arthritis, Gouty; Chromatography, High Pressure Liquid; Gout; Lycium; Purines; Rats; Tandem | 2023 |
Goose astrovirus infection affects uric acid production and excretion in goslings.
Topics: Animals; Astroviridae Infections; Avastrovirus; Avian Proteins; Carrier Proteins; Disease Models, An | 2020 |
Determination of total purine and purine base content of 80 food products to aid nutritional therapy for gout and hyperuricemia.
Topics: Food Analysis; Gout; Hyperuricemia; Purines | 2020 |
Effect of allicin and its mechanism of action in purine removal in turbot.
Topics: Adsorption; Animals; Chromatography, High Pressure Liquid; Cooking; Disulfides; Flatfishes; Food Han | 2020 |
Effects of breeds, tissues and genders on purine contents in pork and the relationships between purine content and other meat quality traits.
Topics: Adipose Tissue, White; Animals; Animals, Inbred Strains; China; Crosses, Genetic; Dietary Fats; Fema | 2018 |
Determination of purine contents in different parts of pork and beef by high performance liquid chromatography.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Gout; Hyperuricemia; Meat; Purines; Red Meat; | 2015 |
Determination of purine contents of alcoholic beverages using high performance liquid chromatography.
Topics: Alcoholic Beverages; Chromatography, High Pressure Liquid; Gout; Guanine Deaminase; Humans; Hyperuri | 2009 |
Gout: is a purine-restricted diet still recommended?
Topics: Alcohol Drinking; Evidence-Based Medicine; Gout; Humans; Purines; Treatment Outcome; Uric Acid | 2009 |
Gout, a derangement of purine metabolism.
Topics: Gout; Humans; Metabolic Networks and Pathways; Purines | 1952 |
Diagnosis and treatment of gouty arthritis.
Topics: Arthritis; Arthritis, Gouty; Colchicine; Gout; Humans; Hyperuricemia; Male; Middle Aged; Probenecid; | 1953 |
The concept of secondary gout; relation to purine metabolism in polycythemia and myeloid metaplasia.
Topics: Anemia, Myelophthisic; Gout; Humans; Myeloproliferative Disorders; Polycythemia; Primary Myelofibros | 1956 |
The concept of secondary gout; relation to purine metabolism in polycythemia and myeloid metaplasia.
Topics: Anemia, Myelophthisic; Gout; Humans; Myeloproliferative Disorders; Polycythemia; Primary Myelofibros | 1956 |
The concept of secondary gout; relation to purine metabolism in polycythemia and myeloid metaplasia.
Topics: Anemia, Myelophthisic; Gout; Humans; Myeloproliferative Disorders; Polycythemia; Primary Myelofibros | 1956 |
The concept of secondary gout; relation to purine metabolism in polycythemia and myeloid metaplasia.
Topics: Anemia, Myelophthisic; Gout; Humans; Myeloproliferative Disorders; Polycythemia; Primary Myelofibros | 1956 |
Intermediary purine metabolism and the metabolic defects of gout.
Topics: Gout; Humans; Metabolic Networks and Pathways; Purines | 1957 |
[Excretion of purine bodies in urine in subjects of gout; chromatographic and spectrophotometric study].
Topics: Gout; Humans; Purines | 1958 |
[Nutrition in gout. Purine-free and low-purine diet].
Topics: Diet; Gout; Humans; Nutrition Assessment; Purines | 1961 |
Purine metabolism in blood of gouty humans.
Topics: Gout; Humans; Metabolic Networks and Pathways; Purines | 1961 |
SUMMARY OF INFORMAL DISCUSSION ON THE ROLE OF PURINE ANTAGONISTS.
Topics: Antimetabolites; Gout; Humans; Leukemia; Mercaptopurine; Pharmacology; Psoriasis; Purines; Pyrazoles | 1963 |
[OUR EXPERIENCES WITH THE TREATMENT OF GOUT].
Topics: Blood Chemical Analysis; Body Fluids; Colchicine; Dietary Carbohydrates; Dietary Fats; Dietary Prote | 1964 |
EXHIBIT ON GOUT.
Topics: Colchicine; Exhibitions as Topic; Gout; Humans; Metabolism; Probenecid; Purines; Sulfinpyrazone; Uri | 1964 |
NEW PROSPECTS IN THE TREATMENT OF GOUTY DYSPURINIA.
Topics: Azaserine; Blood; Drug Therapy; Enzyme Inhibitors; Gout; Leucine; Metabolism; Orotic Acid; Oxidoredu | 1964 |
[CORTICOSTEROID THERAPY OF GOUT].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Drug Therapy; Gout; Humans; Indoles; Indometha | 1964 |
4-HYDROXYPYRAZOLO (3,4-D) PYRIMIDINE (HPP) IN THE TREATMENT OF GOUT: PRELIMINARY OBSERVATIONS.
Topics: Blood; Colchicine; Diet; Diet Therapy; Drug Therapy; Enzyme Inhibitors; Geriatrics; Gout; Humans; Pr | 1964 |
[THE PRACTITIONER AND THE PATIENT WITH GOUT].
Topics: Adrenal Cortex Hormones; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Colchicine; Diagnosis; | 1965 |
URIC ACID IN HUMAN PLASMA. I. INVESTIGATIONS ON THE PRESENCE OF PURINES IN HUMAN BLOOD.
Topics: Blood; Colorimetry; Gout; Humans; Hypoxanthines; Leukemia; Liver Cirrhosis; Oxidoreductases; Purines | 1965 |
[TREATMENT OF GOUTY DYSPURINIA BY PARAMETABOLITES AND, ESPECIALLY, BY A XANTHINE OXIDASE INHIBITOR].
Topics: Drug Therapy; Enzyme Inhibitors; Gout; Humans; Purines; Pyrimidines; Spectrophotometry; Urine; Xanth | 1965 |
THE EFFECTIVENESS OF THE XANTHINE OXIDASE INHIBITOR ALLOPURINOL IN THE TREATMENT OF GOUT.
Topics: Allopurinol; Blood Chemical Analysis; Drug Therapy; Enzyme Inhibitors; Gout; Humans; Metabolism; Pur | 1965 |
THE RENAL EXCRETION OF OXYPURINES.
Topics: Enzyme Inhibitors; Fluids and Secretions; Gout; Hypoxanthines; Kidney; Pharmacology; Physiology; Pro | 1965 |
Plasma glutamine and oxypurine content in patients with gout.
Topics: Blood; Glutamine; Gout; Humans; Plasma; Purines | 1955 |
Impressions of gout.
Topics: Gout; Humans; Purines; Social Behavior; Uric Acid | 1950 |
Uric acid and diet--insights into the epidemic of cardiovascular disease.
Topics: Dairy Products; Diet; Dietary Proteins; Female; Gout; History, 17th Century; History, 18th Century; | 2004 |
Purine-rich foods, dairy and protein intake, and the risk of gout in men.
Topics: Adult; Aged; Alcohol Drinking; Biological Availability; Body Mass Index; Dairy Products; Diet; Diet | 2004 |
[Hyperuricemia and disorders in content of amino acids-purine precursors in patients with autoimmune diseases and gout].
Topics: Amino Acids; Autoimmune Diseases; Gout; Humans; Hyperuricemia; Lipid Peroxides; Purines; Uric Acid; | 2005 |
Management of gout and hyperuricemia.
Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Gout; Humans; Indomethacin; Kidney; Patient Educa | 1984 |
Inherited disorders of purine metabolism--underlying molecular mechanisms.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Gout; Humans; Hypoxanthine Phosphoribosyltra | 1984 |
The rate of purine synthesis de nova in blood mononuclear cells in vitro from patients with familial hyperuricaemic nephropathy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Erythrocytes; Female; Gout; Humans; Kidney Disease | 1984 |
Purine metabolism in women with primary gout.
Topics: Aged; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Prospective | 1994 |
Analysis of abnormalities in purine metabolism leading to gout and to neurological dysfunctions in man.
Topics: Adenylosuccinate Lyase; Aminoimidazole Carboxamide; AMP Deaminase; Gout; Humans; Hypoxanthine Phosph | 1998 |
[Hyperuricemia: explain, ignore or treat?].
Topics: Coronary Disease; Female; Gout; Humans; Hypertension; Kidney Calculi; Male; Purines; Risk; Uric Acid | 1986 |